MIR Software Comparison Table. Multilanguage (18 Languages)

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1 Multilanguage (18 Languages) Test Type Fvc PRE Fvc POST Bronchodilator Fvc Bronchial Challenge 4 4 Vc Mvv 4 4 Generic Oximetry Sleep Oximetry Minute Walking Test Oximetry 4 4 Real Time Spirometry Test Spirometry Test Downloading From Device Real Time Oximetry Test Real Time Plethysmographic Curve 4 Oximetry Test Downloading From Device Pediatric Incentive Program Physical Activity Analysis 4 4 Test Results Management Calculation Of Reference Values LLN And ULN Reference Values 4 4 GLI Standard Supported 4 4 Nhanes III Standard Supported Automatic Interpretation Repeatability Quality Control Grade Quality Control Messages Diagnosis/Comment (free text) Codified Comment 4 4 Customizable Spirometry Parameters 4 4 FVC Cronology 4 4 Delete Single Test Disable Single Test 4 4 Define Manually The Best Spirometry Test 4 4 Define And Mark Artefacts On Oximetry Curve 4 4 Parameters Trend On The Oximetry Test 4 4 Parameters Trend On The Diagnostic Monitoring 4 4

2 Printing FVC Printout Bronchial Challenge Printout 4 4 Sleep Oximetry Printout MINUTE WALKING TEST Printout 4 4 FVC Cronology Printout 4 4 Calibration Printout Multiple FVC printout 4 4 Home Care Printout 4 4 Telemedicine Home Care Monitoring 4 4 Download Data from the Telemedicine Server 4 4 Parameters Trend On The Home Care Monitoring 4 4 ediary 4 4 Data Sharing Database Sharing between workstations 4 Database Import 4 4 Database Export 4 4 Printout Export In Word (.Doc) Format Printout Export In Pdf Format Integration Integration with EMR via FILE OR WEB SERVICE in HL7 format Integration with EMR via TCP SOCKET in HL7 format 4 4 Integration with EMR via FILE in XML format Integration with EMR via FILE in GDT format 4 4 Integration with EMR via FILE in BDT format 4 4 Integration with EMR via FILE in txt format Device Management Device Customization and Configuration 4 4 Updating of the device internal sofware Calibration of the turbine Reusable Turbine FlowMIR Disposable Turbine (MIR International Patent) Connectivity

3 USB BLUETOOTH 4 4 RS232 (SERIAL PORT) 4 4 Spirometry Parameters FVC FEV PEF FEF FEF FET 4 4 PEFF 4 4 FVVC 4 4 FVV1 4 4 FEV1/FVC FEV FEV3 4 4 FEV1/FEV6 4 4 FEF FEF EVol 4 4 FIVC FIV1 4 4 FIV1/FIVC 4 4 PIF 4 4 FEV1/VC FEV3/FVC 4 4 EVC IVC IC 4 4 VC 4 4 ERV 4 4 TV 4 4 VE 4 4 RR 4 4 ti 4 4 te 4 4 TV/tI 4 4 ti/ttot 4 4

4 MVV 4 4 PEF 4 4 PIF 4 4 ELA MVV(cal) 4 4 DTPEF 4 4 FEV FEV05% 4 4 FEV FEV075% 4 4 FEV2 4 4 FEV2% 4 4 FEF FIF FIF FIF R IRV 4 4 Oximetry Parameters Baseline SpO2 (SpO2 Average in first three minutes) 4 4 Mean SpO2 (SpO2 Average during period of analysis) Min SpO2 (SpO2 Minimum during period of analysis) Max SpO2 (SpO2 Maximum during period of analysis) Delta Index [12 s] (Index of SpO2 fluctuation calculated in intervals of 12 seconds) SpO2 <89% Events (Fall of SpO2 below 89% for at least 20 seconds) 4 4 T90 [t<= 89%] (Time passed with SpO2 < 90 % ) T89 [t<= 88%] (Time passed with SpO2 < 89 % ) T88 [t<= 87%] (Time passed with SpO2 < 88 % ) 4 4 T87 [t<= 86%] (Time passed with SpO2 < 87 % ) 4 4 T5 [Δ >5%] (Time passed with SpO2 <= 5 % with respect to SpO2 Mean) Baseline Pulse Rate (Average pulse frequency in the first 3 minutes) 4 4 Mean Pulse Rate (Average pulse frequency during the period of analysis) Min Pulse Rate (Minimum pulse frequency during the period of analysis) 4 4 4

5 Max Pulse Rate (Maximum pulse frequency during the period of analysis) T40 (Time passed with pulse frequency < 40 BPM) T120 (Time passed with pulse frequency > 120 BPM) Tachycardia Event (Tachycardia event of at least increase in pulse frequency above 120 BPM 20 seconds) 4 4 Tachycardia Events (Tachycardia events during the entire period of analysis) 4 4 Tachycardia Duration (Total duration of tachycardia events during the entire period of analysis) 4 4 Bradycardia Event (Bradycardia event Fall of pulse frequency below 40 BPM for at least 20) 4 4 Bradycardia Events (Bradycardia events in the entire period of analysis ) 4 4 Bradycardia Duration (Total duration of the bradycardia events during the entire period of analysis) 4 4 Total Desaturation Events (Desaturation events during the entire period of the analysis) ODI - Desaturation Index (1/h) (Desaturation events by hour of analysis) ODI - in Supine Position ODI - in Non Supine Position Mean Duration (s) (Average duration of desaturation events) Longest Duration (s) (of desaturation events) Desaturation Peak [Nadir] (%) (Minimum Sp02 during desaturation events) 4 4 Mean Desaturation (%) (Average desaturation peak) 4 4 Mean Drop [Delta SpO2 %] (Average SpO2 fall with respect to baseline during the desaturation events) 4 4 Maximum Fall (Delta SpO2 %) (Maximum fall of SpO2 with respect of baseline during the desaturation events) Total Pulse Rate Variation (Variation of pulse frequency events during the entire period of the analysis) Pulse Rate Variation Index (1/h) (Variation of pulse frequency by hour of analysis) NOD 4 [Δ SpO2 >=4%] (Time passed with SpO2 < 4 % with respect to SpO2 base for continual periods above 5 minutes) 4 4 NOD 89 [NOD <=88% Nadir <=85%] (Time passed with SpO2 < 89 % for continued periods above 5 minutes with minimum value <86 % (Nadir)) 4 4 4

6 NOD 90 [NOD <=89%] (Time passed with SpO2 < 90 % for continual periods above 5 minutes ) Initial SpO2 (SpO2 average before Postwalk SpO2 (SpO2 after Initial Pulse Rate (Average pulse frequency before Postwalk Pulse Rate (Pulse frequency after T2 [ΔSpO2>= 2%] (Time passed during walking test with SpO2 < 2 % with respect to SpO2 base) 4 4 T4 [ΔSpO2>= 4%] (Time passsed during SpO2 walking test < 4 % with respect to SpO2 base) 4 4 Total Distance Walked (Distance covered during AUC/Distance (Area under SpO2 curve base relative to distance covered) 4 4 Initial Dyspnea (Grade of dyspnea before Postwalk Dyspnea (Grade of dyspnea after Dyspnea CHG (Variation in grade of dyspnea during Initial Fatigue (Level of fatigue before Fatigue at end of test (Level of fatigue after Fatigue CHG (Variations in level of fatigue during Predicted Distance (Theoretical standard distance) 4 4 % Predicted (% in variations of the distance covered with respect to theoretical standard distance) 4 4 Min Predicted Distance (Theoretical minimum distance) 4 4 % Min Predicted (% of variations of distance covered with respect to theoretical minimum distance) 4 4 Devices Spirotel Spirodoc Spirobank II Minispir Minispir Light 4 Spirobank G Spirobank USB 4 Spirolab III 4 4

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