Colon cancer and normal cell lines

Transcription

1 The Essentials of Life Science Research Globally Delivered Colon cancer and normal cell lines ATCC No. Name Tissue Cell Type Disease Oganism Age Ethnicity Genes Expressed CRL-2577 RKO Carcinoma CRL-2579 RKO-AS45-1 Carcinoma HTB-38 HT-29 CCL-238 SW1417 [SW-1417] CCL-237 SW948 [SW-948] CCL-221 DLD-1 epithelial CCL-228 SW480 [SW-480] grade III, grade III, Dukes' type B, 44 years Caucasian 53 years Caucasian 81 years Caucasian 50 years Caucasian p53 + (wild type) p53 + (underexpressed) secretory component of IgA; carcinoembryonic antigen (CEA); transforming growth factor beta binding protein; mucin, myc +; ras +; myb +; fos +; sis +; p53 +; abl -; ros -; src -, Blood Type A; Rh+; HLA A1, A3, B12, B17, Cw5, HT-29 cells are negative for CD4, but there is cell surface expression of galactose ceramide (a possible alternative receptor for HIV). carcinoembryonic antigen (CEA) 362 ng/10 exp6 cells/10 days; keratin, myc +; ras +; fos +; sis +; p53 -; myb -; abl -; ros -; src -, blood type B; Rh+, The cells are positive for keratin by immunoperoxidase staining., The line is positive for expression of c-myc, H-ras, sis and fos oncogenes. carcinoembryonic antigen (CEA) 7 ng/10 exp6 cells/10 days; specific antigen (CSAp) 750 units in 0.5 ml cell sonicate; keratin, myc +; myb +; ras +; fos +; p53 +; sis -; abl -; ros -; src -, blood type O; Rh+, The cells are positive for keratin by immunoperoxidase staining., The line is positive for expression of c-myc, K-ras, H-ras, N-ras, myb and fos oncogenes. carcinoembryonic antigen (CEA) 0.5 ng/10 exp6 cells/10 days; antigen 3; keratin, myc +; myb + ; ras +; fos +; sis +; p53 +; abl -; ros -; src -, blood type O, DLD-1 cells are positive for p53 antigen expression (the p53 antigen produced has a C -> T mutation resulting in Ser -> Phe at position 241)., The cells are positive for keratin by immunoperoxidase staining., The line is positive for expression of c-myc, K-ras, H-ras, N-ras, myb, sis and fos oncogenes. carcinoembryonic antigen (CEA) 0.7 ng/10 exp6 cells/10 days; keratin; transforming growth factor beta, myc +; myb + ; ras +; fos +; sis +; p53 +; abl -; ros -; src -, HLA A2, B8, B17; blood type A; Rh+, The cells are positive for keratin by immunoperoxidase staining., The line is positive for expression of c-myc, K-ras, H-ras, N-ras, myb, sis and fos oncogenes.

2 CCL-233 SW1116 [SW 1116, SW-1116] CL-188 LS 174T CCL-218 WiDr CCL-220 COLO 320DM CCL COLO 320HSR [COLO 320 HSR] CCL-225 HCT-15 CCL-230 SW403 [SW-403] CCL-231 SW48 [SW-48] CCL-244 HCT-8 [HRT-18] Dukes' type A, grade III, Dukes' type B, grade III, grade IV, ileocecal CCL-247 HCT 116 carcinoma CCL-255 LS123 Epithelial CL-187 LS 180 Dukes' type B, Dukes' type B, CRL HX [HT1080 xeno] fibrosarcoma CRL HP [HT1080 poly] fibrosarcoma CRL-1459 CCD-18Co normal CRL-1539 CCD-33Co CRL-1541 CCD-112CoN CRL-1790 CCD 841 CoN epithelial 73 years Caucasian 58 years Caucasian 55 years Caucasian 55 years Caucasian 51 years Caucasian 82 years Caucasian 67 years carcinoembryonic antigen (CEA) 2654 ng/10 exp6 cells/10 days; keratin, myc +; myb + ; ras +; fos +; sis +; p53 +; abl -; ros -; src -, blood type O; Rh+, The cells are positive for keratin by immunoperoxidase staining., The line is positive for expression of c-myc, K-ras, H-ras, myb, sis and fos oncogenes. carcinoembryonic antigen (CEA), interleukin 10 (IL-10), interleukin 6 (IL-6), mucin, myc +; myb + ; ras +; fos +; p53 +; sis -; abl -; ros -; src -, serologically defined cancer antigen 3;, expressed, HLA A2, B13, B50; Blood type O, The line is positive for expression of c-myc, N-myc, H-ras, N-ras. serotonin; norepinephrine; epinephrine; adrenocorticotropic hormone (ACTH); parathyroid hormone serotonin; norepinephrine; epinephrine; adrenocorticotropic hormone (ACTH); parathyroid hormone carcinoembryonic antigen (CEA) 5.4 ng/10<sup>6</sup> cells/10 days. The cells are positive for keratin by immunoperoxidase staining. carcinoembryonic antigen (CEA) 155 ng/10 exp6 cells/10 days; keratin, blood type O, The cells are positive for keratin by immunoperoxidase staining. carcinoembryonic antigen (CEA) 0.6 ng/10 exp6 cells/10 days; keratin, HLA A32, A33, B27, B35; blood type AB; Rh+, The cells are positive for keratin by immunoperoxidase staining. carcinoembryonic antigen (CEA) 0.5 ng/10 exp6 cells/10 days; alkaline phosphatase; keratin, The cells are positive for keratin by immunoperoxidase staining. carcinoembryonic antigen (CEA) 1 ng per 10<sup>6</sup> cells per 10 days. 65 years Caucasian carcinoembryonic antigen (CEA), 9 ng/ml per 10 exp6 cells per 10 days; mucin 58 years Caucasian 35 years Caucasian 35 years Caucasian 2.5 months Black 7 years Caucasian 22 weeks 21 weeks fetus carcinoembryonic antigen, interleukin 10, interleukin 6, mucin, HLA A2, B13, B50; Blood type O, serologically defined cancer antigen 3;, expressed 2 Order online at call , , or contact your local distributor.

3 CRL-1807 CCD 841 CoTr CRL-1831 FHC Epithelial CRL-1923 Ramos.2G6.4C10 B CRL-2102 C2BBe1 [clone of Caco-2 (ATCC HTB-37)] Enterocyte Burkitt's lymphoma (American) CRL-2578 RKO-E6 Carcinoma, Papilloma, CRL-2780 ATRFLOX [Mutatect] epithelial carcinoma CRL-7213 Hs 255.T CRL-7214 Hs 257.T CRL-7400 Hs 675.T cancer HTB-37 Caco-2 Epithelial HTB-39 SK-CO-1 : ascites CCL-224 COLO 201 : ascites CCL-222 COLO 205 : ascites CRL-7435 Hs 698.T CCL-229 LoVo : connective tissue : left supraclavicular region Dukes' type D, Dukes' type D, grade IV, CCL-248 T84 : lung carcinoma CCL-227 CRL-5972 SW620 [SW-620] SNU-C1 : lymph node : peritoneum 21 weeks 13 weeks 3 years Caucasian immunoglobulin (surface and secreted), CD years Caucasian 46 years Caucasian 71 years Caucasian 72 years Caucasian 65 years Caucasian ataxia telangiectasia and Rad3 related Caucasian keratin, retinoic acid binding protein 1, retinol binding protein 2 myc +; ras +; myb +; fos +; sis +; p53 +; abl -; ros -; src -, Blood Type O; Rh+; HLA A1, A3, B7, B13 70 years Caucasian myc +; ras + ; myb + ; fos +; sis +; p53 +; abl -; ros -; src - 70 years Caucasian 70 years 56 years 72 years American Indian 51 years Caucasian 71 years Asian carcinoembryonic antigen (CEA) 1.5 to 4.1 ng/10 exp6 cells/10 days; keratin; interleukin 10 (IL-10, interleukin-10), The cells are positive for keratin by immunoperoxidase staining. carcinoembryonic antigen (CEA) 908 ng/10 exp6 cells/10 days, myc +; myb + ; ras +; fos +; p53 +; sis -; abl -; ros -; src -, HLA A11, B15, B17, Cw1, Cw3; blood type B, The cells are negative for expression of CSAp (CSAp-) and antigen 3., The line is positive for expression of c-myc, K-ras, H-ras, N-ras, Myb, sis and fos oncogenes. carcinoembryonic antigen (CEA), 600 ng/ml per 10 exp6 cells per 10 days; keratin, The cells are positive for keratin by immunoperoxidase staining. carcinoembryonic antigen (CEA) 0.15 ng/10 exp6 cells/10 days; transforming growth factor alpha; keratin; matrilysin, myc +; myb + ; ras +; fos +; sis +; p53 +; abl -; ros -; src -, blood type A; Rh+, The cells are negative for expression of CSAp (CSAp-) and antigen 3, negative., The cells are positive for keratin by immunoperoxidase staining., The line is positive for expression of c-myc, K-ras, H-ras, N-ras, Myb, sis and fos oncogenes. Order online at call , , or contact your local distributor. 3

4 CL-177 XB-2 epithelial keratinocyte teratoma CRL-1838 M-NFS-60 virus induced myelogenous leukemia CRL-2638 CT26.WT Carcinoma CRL-2639 CT26.CL25 Carcinoma, Leukemia HB-8240 HB-8248 HB-8247 CLT 85 [SKI 294/CLT 85] HT 29/36 [SKI 294/HT 29/36] HT 29/26 [SKI 294/HT 29/26],, Tissue,, Tissue, intestine, Tissue,, CRL NS-3d, spleen HB PCA 31.1, spleen HB PCA 33.28, spleen HB NS-19-9, spleen HB-9397 HB E12H12 CLT 152 [SKI 294/CLT 152], spleen,, Epithelium, Tissue Cancer, Adenocarcinoma, Cancer Cancer, Adenocarcinoma, Cancer Cancer, Cancer Adenocarcinoma Carcinoma, Carcinoma Carcinoma, Carcinoma Carcinoma, Cancer Cancer, Cancer CRL TAC-1 fibroblast CCL-242 GPC-16 Saguinus oedipus Cavia porcellus 6 years old H-2d beta galactosidase (beta-gal), H-2d, The lethal subclone CT26.CL25 (ATCC CRL-2639) was selected for use in all in vitro and in vivo studies because of its stable high expression of both beta-gal and the class I molecule H-2 Ld. immunoglobulin; monoclonal antibody; against human immunoglobulin; monoclonal antibody; against human immunoglobulin; monoclonal antibody; against a dalton glycoprotein (gp29) expressed in human cells immunoglobulin; monoclonal antibody; against carcinoembryonic antigen (CEA) immunoglobulin; monoclonal antibody; against human carcinoma associated antigens (CCAA) immunoglobulin; monoclonal antibody; against human carcinoma associated antigens (CCAA) immunoglobulin; monoclonal antibody; against carcinoma monosialoganglioside immunoglobulin; monoclonal antibody; against human 40 kda ic protein immunoglobulin; monoclonal antibody; against a dalton protein expressed in human epithelial cells of the gastrointestinal tract mucosa (stomach, small intestine, esophagus and ) keratin, The cells are positive for keratin by immunoperoxidase staining. 4 Order online at call , , or contact your local distributor.

5 PHONE WEB CB American Type Culture Collection. The ATCC trademark and trade name, any and all ATCC catalog numbers and any other trademarks listed in this publication are trademarks of the American Type Culture Collection unless indicated otherwise. These products are for laboratory use only. Not for human or diagnostic use. ATCC products may not be resold, modified for resale, used to provide commercial services or to manufacture commercial products without prior ATCC written approval.