Breast cancer and normal cell lines
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1 The Essentials of Life Science Research Globally Delivered Breast cancer and normal cell lines ATCC No. Name Tissue Cell Type Disease Oganism Age Ethnicity Genes Expressed CRL-7227 Hs 281.T CRL-7245 Hs 343.T CRL-7253 Hs 362.T HTB-132 HTB-27 CRL-2351 HTB-22 HTB-26 HTB-128 HTB-130 HTB-21 HTB-30 MDA-MB-468 MDA-MB-361 AU565 [AU-565] MCF7 MDA-MB-231 MDA-MB-415 MDA-MB-436 CAMA-1 SK-BR-3 : brain : malignant pleural : pleural : pleural : pleural : pleural : pleural : pleural 37 years 47 years 78 years 51 years Black 40 years wnt7h + 43 years 69 years 51 years 38 years, 43 years tubulin; actin Blood Type AB; HLA Aw23, Aw30, B27, Bw35, Cw2, Cw4 (patient) her2/neu + (overexpressed); her3 +; her4 +; p53 + insulin-like growth factor binding proteins (IGFBP) BP-2; BP-4; BP-5, Blood Type O; Rh+ amelogenin (X chromosome)(amelex), Blood Type O 51 years Blood type O; Rh +; HLA A10, A11, B12, B18 43 years Blood Type A; Rh+; HLA A11, Bw22(+/-), B40, B18
2 CRM-HTB-26 MDA-MB-231 : pleural CRL-2116 JC mammary gland, -like CRL MAT B III mammary gland CRL-1743 NMU mammary gland CRL-1747 RBA mammary gland CRL-3127 CRL-3180 CRM-HTB- 26D UACC-1179 UACC-2087 MDA-MB-231 CRL-7222 Hs 274.T CRL-7477 Hs 739.T CRL-7480 Hs 741.T ; derived from metastatic site: pleural fluid : pleural -like CRL-6602 SMT/2A LNM mammary gland CRL-7486 Hs 748.T HTB-125 HTB-126 HTB-19 CRL-7347 CRL-1897 HTB-121 HTB-122 Hs 578Bst Hs 578T BT-20 Hs 579.Mg UACC-812 BT-483 BT-549 CRL-7345 Hs 574.T HTB-20 BT-474 /duct /duct, Myo fibroblast cancer Carcinoma Carcinoma Carcinoma ductal ductal ductal ductal ductal 51 years 1.5 years 50 days 50 days 61 years 51 years 51 years 66 years 52 years Asian 47 years 48 years 74 years 74 years collagen (Type IV); plasminogen activator; prostaglandins; keratin keratin 74 years HLA A1, Bw16 (+/-) 43 years 23 years 72 years 60 years 2 Order online at call , , or contact your local distributor.
3 CRL-1500 CRL-2865 HTB-133 HTB-23 HTB-25 CRL-1504 ZR-75-1 T47D-KBluc T-47D MDA-MB-134-VI MDA-MB-175-VII ZR /duct: ascites /duct: pleural /duct: pleural /duct: pleural /duct: pleural : ascites transfected with reporter plasmid ductal ductal ductal ductal ductal ductal CRL-3121 UACC-2648 /duct -like ductal CRL CRL CRL CRL-7329 CRL-2983 MCF 10A MCF 10F MCF-10-2A Hs 564(E).Mg UACC-3199 CRL-7236 Hs 319.T CRL-2988 CRL-3166 UACC-3133 UACC-732 / duct: axillary lymph node : pleural ; derived from metastatic site: pleural fluid, Myo -like fibrocystic disease fibrocystic disease fibrocystic disease infiltrating ductal infiltrating ductal of the infiltrating ductal cell infiltrating lobular of inflammatory of the CRL-2755 EMT6 mammary HTB-24 HTB-131 MDA-MB-157 MDA-MB-453 /medulla : pericardial medulallary metastatic 63 years 54 years 54 years 47 years 56 years Black 47 years Black 58 yrs 36 years 36 years 36 years 53 years 58 years 42 years 52 years 33 years 44 years Black 48 years mucin (apomucin, MUC-1, MUC-2) Blood Type O; Rh+ cytokeratin 19. The cells are positive for cytokeratins and milk fat globule antigen. c-erbb-2 positive Blood Type B; Rh- Order online at call , , or contact your local distributor. 3
4 CRL-8400 CSMalphabeta6C [CSMab6C] mammary gland fibroblast Papilloma CRL-8399 CMH1a mammary gland Papilloma, hepatitis, hepatitis CRL-8401 CRL-1902 CMalphabeta1h [CMab1h] UACC-893 CRL-7482 Hs 742.T mammary gland fibroblast Papilloma, Papilloma, Papilloma CRL T1 mammary gland CRL-2324 CRL-2338 CRL-2320 CRL-2321 CRL-2322 CRL-2335 CRL-2329 HCC1395 HCC1954 HCC1008 HCC1143 HCC1187 HCC1806 HCC1500 /duct /duct /duct: lymph node /duct /duct /duct, lymphoblast primary ductal scirrhous This tumor is an animal stage IV human cancer. TNM stage I, grade 3, primary ductal TNM stage IIA, grade 3, ductal TNM stage IIA, grade 3, ductal TNM stage IIA, grade 3, primary ductal TNM stage IIA, grade 3, primary ductal TNM stage IIB, grade 2, primary acantholytic squamous cell TNM stage IIB, grade 2, primary ductal 57 years 71 years 43 years 61 years 67 years 52 years 41 years, East Indian Black, 60 years Black 32 years Black glycoprotein hormones, alpha polypeptide(chorionic gonadotropin, alpha polypeptide, luteinizing hormone alpha) [CGA], chorionic gonadotropin, beta polypeptide, glycoprotein hormones, alpha polypeptide surface antigen [sag] glycoprotein hormones, alpha polypeptide(chorionic gonadotropin, alpha polypeptide, luteinizing hormone alpha) [CGA], chorionic gonadotropin, beta polypeptide, glycoprotein hormones, alpha polypeptide glycoprotein 2 (EGP2), cytokeratin 19, her2/neu -, p53 +, The cells are negative for expression of Her2-neu but positive for expression of p53., The cells are negative for expression of estrogen receptors (ER -) according to depositor and negative for expression of progesterone receptors (PR -). HCC1954 overexpresses her2/neu and is positive for the cell specific marker Glycoprotein 2 and for cytokeratin 19, and is negative for expression of estrogen receptor (ER) and progesterone receptor (PR). glycoprotein 2 (EGP2), cytokeratin 19, her2/ neu +, p53 +, The cells are positive for expressions of Her2-neu and p53 oncogenes., The cells are negative for expression of estrogen receptor (ER) and for expression of progesterone receptor (PR). glycoprotein 2 [EGP2]; cytokeratin 19, her2/ neu -; p53 +, The cells are negative for expression of Her2-neu but positive for expression of p53., HCC1143 is positive for the cell specific marker Glycoprotein 2 and for cytokeratin 19, and is negative for expression of estrogen receptor (ER) and progesterone receptor (PR). glycoprotein 2 (EGP2), cytokeratin 19, her2/neu -, p53 + glycoprotein 2 [EGP2]; cytokeratin 19, her2/neu -, p53 -, The cells are negative for expression of Her2-neu and for expression of p53., The cells are negative for expression of estrogen receptor (ER) and for expression of progesterone receptor (PR). glycoprotein 2 (EGP2), cytokeratin 19, her2/ neu -, p53 +, The cells are negative for expression of Her2-neu but positive for expression of p53., The cells are positive for expression of estrogen receptor (ER) and for expression of progesterone receptor (PR). 4 Order online at call , , or contact your local distributor.
5 CRL-2314 CRL-2336 CRL-2340 CRL-2316 CRL-2331 CRL-2326 CRL-2343 CRL-2315 CRL-2330 HCC38 HCC1937 HCC2157 HCC202 HCC1599 HCC1419 HCC2218 HCC70 HCC1569 /duct /duct /duct /duct /duct /duct /duct lymphoblast,, lymphoblast, lymphoblast TNM stage IIB, grade 3, primary ductal TNM stage IIB, grade 3, primary ductal TNM stage IIIA, grade 2, primary ductal TNM stage IV, grade 3, primary metaplastic 50 years 23 years 48 years 82 years 44 years, Black,, 42 years Hispanic 38 years, 49 years Black 70 Black The cells are negative for expression of Her2-neu but positive for expression of p53, HCC38 is positive for the cell specific marker Glycoprotein 2 [EGP2] and for cytokeratin 19, and is negative for expression of estrogen receptor (ER) and progesterone receptor (PR). glycoprotein 2 (EGP2), cytokeratin 19, BRCA1 (mutated, insertion C at nucleotide 5382), her2/neu -, p53 -, The cells are negative for expression of Her2-neu and for expression of p53., The cells are negative for expression of estrogen receptor (ER) and progesterone receptor (PR) glycoprotein 2 [EGP2]; cytokeratin 19, her2/neu +, p53 +, The cells are positive for expression of Her2-neu and for expression of p53., The cells are negative for expression of estrogen receptor (ER -), but positive for expression of progesterone receptor (PR +). glycoprotein 2 [EGP2]; cytokeratin 19, her2/neu +, p53 -, The cells are positive for expression of Her2-neu, but are negative for expression of p53., The cells are negative for expression of estrogen receptor (ER -) and progesterone receptor (PR -). glycoprotein 2 [EGP2]; cytokeratin 19, her2/neu -, p53 -, The cells are negative for expression of Her2-neu and for expression of p53., The cells are negative for expression of estrogen receptor (ER) and for expression of progesterone receptor (PR). glycoprotein 2 [EGP2]; cytokeratin 19, her2/ neu +, p53 -, The cells overexpress Her2-neu but are negative for expression of p53. HCC1419 is positive for the cell specific marker glycoprotein 2 (EGP2) and for cytokeratin 19. The cells are negative for expression of estrogen receptor (ER) and for expression of progesterone receptor (PR). glycoprotein 2 [EGP2]; cytokeratin 19, her2/ neu +, p53 +, The cells are highly positive for expression of Her2/neu, and are also positive for expression of p53., The cells are negative for expression of estrogen receptor (ER -). glycoprotein 2 [EGP2]; cytokeratin 19, her2/neu -, p53 + (overexpressed), The cells overexpress p53, and are negative for the expression of Her2-neu oncogenes., The depositor of CRL-2315 initially reported the cells were positive for estrogen receptors. glycoprotein 2 [EGP2]; cytokeratin 19, her2/ neu +, p53 -, positive for expression of Her2-neu and negative for expression of p53., The cells are negative for expression of estrogen receptor (ER) and for expression of progesterone receptor (PR) by immunohistochemistry, but PR expression was detectable at a low level by cytosolic protein assay. Order online at call , , or contact your local distributor. 5
6 CRL-2327 HCC1428 mammary gland; : and pleural CRL-1616 C127I mammary gland CRL CRL CRL-2713 MCF-12A MCF-12F MDA-kb2 CRL-7365 Hs 605.T CRL-7940 HTB-123 CRL-8798 CRL-8799 SW527 [SW 527, SW-527] DU A1 184B5 CRL-7721 MB 157 /epithelium /epithelium /pleural : pleural CRL-6299 CMMT mammary gland CCL-51 MMT mammary gland CRL-1615 CL-S1 mammary gland CRL-1636 NMuMG mammary gland CRL-1804 C127: LT mammary gland CRL-6376 MM3MG mammary gland TNM stage IV, grade 4, visualization of sarcoma virus-induced foci and for an in vitro quantitative assay for bovine papilloma virus. Host for transfection with plasmids containing bovine papilloma virus DNA., visualization of sarcoma virusinduced foci and for an in vitro quantitative assay for bovine papilloma virus. Host for transfection with plasmids containing bovine papilloma virus DNA., transfection with plasmids containing bovine papilloma virus DNA., s for transformation with bovine papilloma virus DNA plasmid Macaca mulatta 49 years 60 years, 60 years 48 years 61 years HCC1428 cells are positive for the expression of glycoprotein 2 [EGP2]; cytokeratin 19 mucin, milk fat globule membrane antigen, sialomucin, The cells are positive for cytokeratins 8, 14 and 18, and negative for cytokeratin 19. Cells derived from a floating population are available (see MCF-12F, ATCC CRL-10783). luciferase, androgen receptor 70 years blood type A; Rh+ 70 years 21 years 21 years 48 years Black plasminogen activator (low amounts) 6 Order online at call , , or contact your local distributor.
7 CRL-6378 MM5MTC mammary gland CRL /+ MGT mammary gland CRL-2283 LA7 mammary gland CRL-6599 Rn2T mammary gland CRL-6230 CF37.Mg mammary gland CRL-6232 CF41.Mg mammary gland CRL-7336 Hs 566(B).T CRL-7368 Hs 606.T CRL-3063 Eph4Ev Mammary Epithelium CRL-3069 B-MEKDD 116 Mammary CRL-3071 Eph Mammary CRL-3086 M158 Mammary CRL-3090 NF639 Mammary CRL-3092 Ac 711 Mammary CRL-1637 Mm5MT mammary gland CRL-7242 Hs 329.T CRL-7256 Hs 371.T CRL-7145 Hs 190.T CRL-7246 Hs 344.T CRL-7248 Hs 350.T CRL-7379 Hs 617.Mg CRL-7574 Hs 841.T CRL-7583 Hs 849.T CRL-7584 Hs 851.T Canis familiaris Canis familiaris 2 years 2 years 10 years 35 years 44 years 54 years 28 years 11 years 49 years 55 years 71 years 48 years 41 years 61 years mouse mammary tumor virus (MMTV) and MMTV antigens Order online at call , , or contact your local distributor. 7
8 CRL-7596 Hs 861.T CRL-7612 Hs 875.T CRL-6373 MM2MT mammary gland CRL-6449 RIIIMT mammary gland CRL-6598 Rn1T mammary gland CRL-6231 CF38.Mg mammary gland CRL-6228 CF34.Mg spontaneous tumor Canis familiaris Canis familiaris 42 years 21 years 2 years 2 years 10 years PHONE tech@atcc.org WEB CB American Type Culture Collection. The ATCC trademark and trade name, any and all ATCC catalog numbers and any other trademarks listed in this publication are trademarks of the American Type Culture Collection unless indicated otherwise. These products are for laboratory use only. Not for human or diagnostic use. ATCC products may not be res, modified for resale, used to provide commercial services or to manufacture commercial products without prior ATCC written approval.
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The Essentials of Life Science Research Globally Delivered Colon cancer and normal cell lines ATCC No. Name Tissue Cell Type Disease Oganism Age Ethnicity Genes Expressed CRL-2577 RKO Carcinoma CRL-2579
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