CURRICULUM VITÆ 1. Personal data 2. Academic degrees 3. Previous activity and current status 4. Experience as scientific adviser
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1 CURRICULUM VITÆ 1. Personal data Name: Clara Cecília Santana Sousa Birth date: 18 of May 1978 Adress: Rua de Jorge Viterbo Ferreira, N Porto 2. Academic degrees In 2011 finished the integrated Master in Pharmaceutical Sciences at Faculty of Pharmacy, University of Porto. In 2008 finished the PhD in Chemistry at Faculty of Sciences, University of Porto. In 2004 finished the Maser Degree in Chemistry at Faculty of Sciences, University of Porto. In 2001 finished the degree in Chemistry at Faculty of Sciences, University of Porto. 3. Previous activity and current status From July 2011 to the present: Post-doctoral researcher at REQUIMTE-Faculty of Pharmacy, University of Porto. From July 2009 to July 2011: Post-doctoral researcher at CIQ-Faculty of Sciences, University of Porto. June 2009: Teacher at Catholic University of Portugal. October 2004 to September 2004: PhD research grant from Fundação para a Ciência e Tecnologia. May 2004 to September 2004: researcher at CIQ-Faculty of Sciences, University of Porto. May 2003 to November 2003: Quality control supervisor at HANNA-Instruments. 4. Experience as scientific adviser PhD co-supervisor of João Francisco Tomaz Santos Botelho. Thesis: Development of spectroscopic methods (MALDI-TOF MS and FTIR) for rapid identification of Acinetobacter spp. and clonal lineages of A. baumannii. PhD co-supervisor of Liliana de Jesus Vieira da Silva (SFRH/BD/88028/2012). Thesis: Drivers of Acinetobacter baumannii population dynamics and virulence. Co-supervisor of several ungraduated students working in the subject of spectroscopic techniques FTIR and MALDI-TOF MS. 1
2 5. Participation in R&D projects: As a principal researcher: 1- Exploratory FCT project (EXPL/DTP-SAP/1797/2013)- Optimization of MALDI-TOF MS for the assessment of bacterial cell viability towards a potential application in food industry. The amount granted is EUR ; Duration: 1 year (February February 2015) As a researcher: 2- Exploratory FCT project (EXPL/DTP-EPI/0196/2012)- Validation and optimization of MALDI-TOF for identification and tracking of clinically relevant Escherichia coli clones and antibiotic resistance mechanisms: a translational approach. The amount granted is EUR ; Duration: 1 year (April April 2014) 3- ESCMID Research Grant 2012 Validation and optimization of high-throughput methods (MALDI-TOF, FT-IR) to identify and track Escherichia coli clinically relevant clones. The amount granted is EUR ; Duration: 2 years (September August 2014) 4- FCT Project (PTDC/AAC-AMB/103386/2008)- Estarão as aquaculturas a produzir mais do que peixe? Detecção de resistência a agentes antimicrobianos num nicho ecológico pouco estudado. The amount granted is EUR ; Duration: 1 year (January June 2013) 5- Multidisciplinary Project funded by Reitoria da Universidade do Porto- Genotypic and high-troughput methodologies for tracing the emerging pathogen Escherichia albertii. The amount granted is EUR 3500; Duration: 1 year (January December 2011) 6. Published works 6.1. Chapter in book 1. Sousa C, Lopes J Infrared spectroscopy detection coupled to chemometrics to characterize foodborne pathogens at a sub-species level. In: Mathematical and Statistical Methods in Food Science and Technology, Chapter 20, pp , edited by Daniel Granato and Gaston Ares, John Wiley & Sons, Ltd (in press) 6.2. Papers in international scientific periodicals with referees 1. Sousa C, Novais Â, Magalhães A, Lopes J, Peixe L Widespread high-risk B2 and D Escherichia coli clones depicted by Fourier Transform Infrared Spectroscopy. Scientific Reports, 3: Sousa C, Matos M, Morais V Energetics and stability of azulene: from experimental to high-level quantum chemical calculations. Journal of Chemical Thermodynamics. DOI: /j.jct
3 3. Sousa C, Santos L, Matos M, Morais V Energetics of 2- and 3-coumaranone isomers: a combined calorimetric and computational study. Journal of Chemical Thermodynamics, 67: Vaz M, Meirinhos-Soares L, Sousa C, Ramirez M, Melo-Cristino J, Lopes J Serotypes discrimination of encapsulated Streptococcus pneumoniae strains by Fouriertransform infrared spectroscopy. Journal of Microbiological Methods, 93(2): Sousa C, Matos M, Morais V Experimental and Computational Thermochemistry of 6,7-Dihydro-4(5H)-benzofuranone. Journal of Chemical Thermodynamics, 56: Sousa C, Grosso F, Meirinhos-Soares L, Peixe L, Lopes J Identification of carbapenem-resistant Acinetobacter baumannii clones using infrared spectroscopy. Journal of Biophotonics, DOI: /jbio IF: Sousa C, Matos M, Morais V Calorimetric and computational study of 7- hydroxycoumarin. Journal of Chemical Thermodynamics, 43: IF: Sousa C, Matos M, Morais V When theory and experiment hold hands: The thermochemistry of -pyrone derivatives. Journal of chemical Thermodynamics, 43: IF: Sousa C, Morais V, Matos M Energetics of the isomers: 3- and 4- hydroxycoumarin. Journal of Chemical Thermodynamics, 42: IF: Matos M, Sousa C, Morais V Experimental and Computational Study of the Energetics of Methoxycoumarins. Journal of Molecular Structure: THEOCHEM, 946: IF: Matos M, Sousa C, Morais V Thermochemistry of chromone- and coumarin-3- carboxylic acid. Journal of Thermal Analysis and Calorimetry, 100: IF: Matos M, Sousa C, Miranda M, Morais V, Liebman J Energetics of Coumarin and Chromone. Journal of Physical Chemistry B, 113(32): IF: Sousa C, Matos M, Morais V Energetics of Flavone and Flavanone. Journal of Chemical Thermodynamics, 41(12): IF: Matos M, Sousa C, Morais V Energetics of Hydroxytetralones: A calorimetric and computational thermochemical study. Journal of Chemical Engineering Data, 54(8): IF: Matos M, Sousa C, Morais V Experimental and Computational Thermochemistry of the Isomers: Chromanone, 3-isochromanone and Dihydrocoumarin. Journal of Chemical Thermodynamics, 41: IF: Matos M, Sousa C, Morais V Thermochemical Study of Some Methoxytetralones. Journal of Chemical Thermodynamics, 41: IF: Matos M, Sousa C, Morais V Experimental and Theoretical Thermochemistry of -tetralone. Journal of Chemical Thermodynamics, 40: IF:
4 18. Matos M, Sousa C, Morais V Experimental and Computational Thermochemistry of 1,4-benzodioxan and its 2-R derivatives. Journal of Chemical Thermodynamics, 40 (10): IF: Matos M, Sousa C, Morais V Experimental and Computational Thermochemistry of 1,4-Benzodioxan and its 6-R derivatives. Journal of Physical Chemistry A, 112 (34): IF: Matos M, Morais V, Sousa C, Roux M, Notario R, Liebman J The Energetics of Naphthalene Derivatives, IV: A calorimetric and calculational thermochemical study of the isomeric naphthalenemethanols. Journal of Molecular Physics, 105 (13-14): Matos M, Sousa C, Morais V Combined Experimental and Computational Study of the Thermochemistry of 1,3-benzodioxol derivatives. Journal of chemical Engeneering Data, 52 (3): Matos M, Sousa C, Monte M, Almeida A, Morais V Thermodynamic study of sesamol, piperonyl alcohol, piperonyl acid and homopiperonylic acid: a combined experimental and theoretical investigation. Organic & Biomolecular Chemistry, 2 (6): Communications in scientific meetings 7.1. Oral 1. Morais V, Matos C, Sousa C. Energetics and stability of azulene from experimental thermochemistry and from high-level quantum chemical calculations, 10 th Mediterranean Conference on Calorimetry and Thermal Analysis, MEDICTA 2011, Porto- Portugal Posters in conferences 1. Botelho J, Sousa C, Silva L, Grosso F, Nemec A, Lopes A, Peixe L. Acinetobacter calcoaceticus-acinetobacter baumannii complex species depicted by MALDI-TOF MS and multivariate data analysis. 13º Congresso Nacional de Microbiologia e Biotecnologia, MICROBIOTEC13, Aveiro-Portugal Silva L, Sousa C, Grosso F, Peixe L. First description of Acinetobacter pittii clinical isolates harboring bla OXA-58 and bla OXA-23 in a Portuguese Hospital. 13º Congresso Nacional de Microbiologia e Biotecnologia, MICROBIOTEC13, Aveiro-Portugal Branquinho R, Sousa S, Osório H, Meirinhos-Soares L, Lopes J, Abdulmawjood A, Klein G, Pintado ME, Peixe L. Bacillus invictus sp. nov., a new species isolated from medicinal products in Portugal. 13º Congresso Nacional de Microbiologia e Biotecnologia, MICROBIOTEC13, Aveiro-Portugal
5 4. Sousa C, Rodrigues C, De Scheerder V, Machado E, Novais Â, Peixe L. Fourier Transform Infrared Spectroscopy (FTIR) as an alternative epidemiological typing tool for discrimination of Klebsiella pneumoniae clones. 10 th International Meeting on Microbial Epidemiological Markers (IMMEM-10), Paris- França Sousa C, Botelho J, Silva L, Grosso F, Nemec A, Lopes A, Peixe L. Improvement on the discrimination of the Acinetobacter calcoaceticus-acinetobacter baumannii complex species by a combined MALDI-TOF MS and chemometric approach. 10 th International Meeting on Microbial Epidemiological Markers (IMMEM-10), Paris- França Sousa C, Silva L, Grosso F, Lopes J, Peixe L. Fast Identification of clinically relevant Acinetobacter baumannii clones by Fourier Transform Infrared Spectroscopy. Acinetobacter 2013, Colónia- Alemanha Sousa C, Silva L, Nemec A, Lopes J, Peixe L. Rapid and accurate identification of the species of Acinetobacter calcoaceticus-acinetobacter baumannii complex spp. by Fourier Transform Infrared Spectroscopy (FTIR). European Congress of Clinical Microbiology and Infectious Diseases, ECCMID2013, Berlin- Alemanha Sousa C, Novais Â, Magalhães A, Lopes J, Peixe L. Quick and reliable discrimination of clinically relevant Escherichia coli clones by Fourier Transform Infrared Spectroscopy (FTIR). European Congress of Clinical Microbiology and Infectious Diseases, ECCMID2013, Berlin- Alemanha Novais Â, Sousa C, Fernandez-Olmos A, Lopes J, Coque TM, Cantón R, Peixe L. Discrimination of major Escherichia coli clones by Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). European Congress of Clinical Microbiology and Infectious Diseases, ECCMID2013, Berlin- Alemanha Magalhães A, Sousa C, Novais Â, Lopes J, Peixe L. Discrimination of Escherichia coli clones by Fourier Transform Infrared Spectroscopy. Congresso Nacional de Jovens Investigadores da Universidade do Porto, IJUP2013, Porto- Portugal Sousa C, Grosso F, Peixe L. Motility in non-flagellate multi-drug resistant Acinetobacter baumannii lineages: the answer for its persistence? International Congress of the Society for Microbial Ecology and Disease, SOMED2012, Valencia- Spain Sousa C, Pires J, Novais Â, Peixe L. Tracing the emerging pathogen Escherichia albertii. Congresso Nacional de Jovens Investigadores da Universidade do Porto, IJUP2012, Porto- Portugal Leirosa S, Sousa C, Sottomayor MJ, Pinto M. Interaction of 3,4-dihydroxyxanthone with double stranded DNA. Congresso Nacional de Jovens Investigadores da Universidade do Porto, IJUP2012, Porto- Portugal
6 14. Sousa C, Grosso F, Peixe L, Lopes J. High-throughput methodologies for tracing Acinetobacter baumannii. 11º Congresso Nacional de Microbiologia e Biotecnologia, MICROBIOTEC 11, Braga- Portugal Sousa C, Matos M, Morais V. Experimental and theorethical thermochemistry of 6,7- dihydro-5(5h)benzofuranone. 10 th Mediterranean Conference on Calorimetry and Thermal Analysis, MEDICTA 2011, Porto- Portugal Sousa C, Matos M, Morais V. Estudo experimental e computacional da energética dos isómeros 2- e 3-coumaranona. XXII Encontro Nacional da Sociedade Portuguesa de Química, Braga- Portugal Grosso F, Sousa C, Quinteira S, Meirinhos-Soares L, Lopes J, Peixe L. Characterization of carbapenem-resistant Acinetobacter baumannii population using genomic-based typing methods and FTIR spectroscopy. 9 th International Meeting on Microbial Epidemiological Markers, Alemanha Morais V, Sousa C, Matos A. The energetics of methoxycoumarins. 9º Encontro Nacional de Química-Física da Sociedade Portuguesa de Química, 1 st Iberian Meeting on Ionic Liquids, Aveiro- Portugal Sousa C, Matos M, Morais V. Experimental and Theoretical Thermochemistry of - tetralone. 19 th IUPAC Conference on Physical Organic Chemistry, Santiago de Compostela- Espanha Sousa C, Matos M, Morais V. Experimental and Theoretical Thermodynamic Study of Methylxantines with Pharmacological Interest. 19 th IUPAC Conference on Physical Organic Chemistry, Santiago de Compostela- Espanha Sousa C, Matos M, Morais V. Estudo termoquímico, experimental e teórico, de algumas hidroxi-tetralonas. XXI Encontro da Sociedade Portuguesa de Química, Porto- Portugal Sousa C, Sampaio C. HUNTINGTON, APOMORFINA E DIETA, HIPO OU HIPERCALÓRICA? IV as Jornadas Monográficas de Química Farmacêutica, I as Jornadas Monográficas de Alimentação Humana, Porto- Portugal Sousa C, Matos M, Morais V. Experimental and theorthical thermochemistry of coumarin and 7-hydroxycoumarin (umbeliferone). 8 th Mediterranean Conference on Calorimetry and Thermal Analysis, Palermo- Itália Sousa C, Matos M, Morais V. Comparative Thermochemistry of 1,4-Benzodioxan and 1,3- Benzodioxole Derivatives. 8º Encontro Nacional de Química-Fsica, SPQ, Luso- Portugal Sousa C, Matos M, Morais V. Experimental and theorethical thermochemistry of 1,4- benzodioxan and some derivatives. 9 th European Symposium on Thermal Analysis and Calorimetry, ESTAC, Cracóvia- Polónia
7 26. Sousa C, Matos M, Morais V. Experimental and theorethical thermochemistry of chromone and two acid derivatives. Calorimetry and Thermal Analysis Conference, CALCAT 06, Santiago de Compostela- Espanha Sousa C, Matos M, Morais V. Thermodynamic study of 1,4-benzodioxane derivatives: a combined experimental and theoretical investigation. 7th Mediterranean Conference on Calorimetry and Thermal Analysis, MEDICTA 2005, Thessaloniki- Grécia Sousa C, Matos M, Morais V, Liebman J. Thermodynamic study of 1-naphthalene- and 2-naphthalenemethanol: a combined experimental and theoretical investigation. 7º Encontro Nacional de Química-Fsica, SPQ, Porto- Portugal Sousa C, Matos M, Morais V. O efeito anomérico em derivados do 1,2- metilenodioxibenzeno. XIX Encontro Nacional da Sociedade Portuguesa de Química, Coimbra- Portugal Sousa C, Matos M, Morais V, Ribeiro da Silva M. Calorimetrical and Theoretical Study of (Methilenedioxy)benzene Derivatives. 6º Encontro Nacional de Química-Física, SPQ, Lisboa- Portugal Matos M, Monte M, Almeida R, Sousa C, Morais V, Ribeiro da Silva M. Vapour Pressures, Enthalpies of Combustion and Formation of (Methilenedioxybenzene) Alcohols and Acids: an Experimental and Theoretical Approach. 6 th Mediterranean Conference on Calorimetry and Thermal Analysis, MEDICTA 2003, Porto- Portugal
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