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1 BRAND PROFILE DATASHEET DASSAULT SYSTEMES, BIOVIA Headquartered in San Diego, California, Dassault Systèmes Biovia Corp. (BIOVIA) provides a scientific collaborative environment for advanced biological, chemical and materials experiences supporting science- and process-based industries.

2 BIOVIA VIRTUAL BIOSPHERE AND MATERIALS BIOVIA solutions create an unmatched scientific innovation environment that can help science- and process-driven companies develop better products faster and more cost effectively. The industry-leading BIOVIA portfolio integrates the diversity of science, experimental processes and information requirements from discovery to manufacturing with proven capabilities in: Collaborative Science Faster discovery through improved multi-disciplinary collaboration, modeling and simulation, data management/informatics and decision making for biologics, chemicals and materials Unified Lab Management Increased efficiency and compliance through standardized, role-based, end-to-end laboratory workflows built on a single technology foundation. This enables scientific teams to manage laboratory resources, processes and interfaces while sharing data and information internally across the organization and externally with partners Process Production Operations Improved understanding of critical process drivers with validation-ready process and quality data access, aggregation, contextualization, analysis and reporting Quality and Regulatory Management Enhanced support for global quality content, policies and procedures along with comprehensive document and process management capabilities BIOVIA solutions are used by more than 2,000 companies in the Life Sciences, Energy/Process/Utilities, Consumer Packaged Goods/Retail, Transportation/Mobility and High Technology sectors, as well as academic and government entities. Customers include 10 of the top 10 pharmaceutical companies, 20 of the top 25 biotech companies, 7 of the top 10 chemical companies, 4 of the top 5 consumer packaged goods companies, 5 of the top 10 oil and gas companies and 5 of the top 5 aerospace companies. PRODUCTS AND SERVICES BIOVIA Foundation The BIOVIA Foundation (previously Accelrys Enterprise Platform) is the basis of our software and services offerings and is central to our strategy to develop and deliver scientific product lifecycle management software. The BIOVIA Foundation s open, scientifically aware, serviceoriented architecture allows organizations to integrate and deploy broad scientific solutions spanning data management and informatics, enterprise lab management, modeling and workflow automation. The BIOVIA Foundation leverages our deep domain expertise in chemistry, biology and materials science, informatics, predictive science, digital laboratory management, process data analytics and regulatory compliance and quality. BIOVIA s foundational technology manages structured and unstructured information encountered early in the innovation cycle, as well as highly structured data from quality and manufacturing. Collaborative Science Scientific Workflow Authoring/Automation BIOVIA Pipeline Pilot: Built on the BIOVIA Foundation, BIOVIA Pipeline Pilot enables scientists to rapidly create, test and publish scientific services that automate the process of accessing, analyzing and reporting scientific data. Pipeline Pilot protocols automate the scientific analysis of data and enable researchers to rapidly explore, visualize and report results. BIOVIA Component Collections: Extensive scientific Component Collections rapidly and cost-effectively deliver advanced imaging, modeling and analytics capabilities supporting scientific workflows from discovery to manufacturing. Modeling and Simulation BIOVIA Modeling and Simulation Software allows scientists to perform computations of chemical, biological and materials properties; to simulate, visualize and analyze chemical and biological systems; and to communicate the results to other scientists. Scientists can investigate and test hypotheses in silico prior to costly experimental implementation, thus reducing the time and expense involved in bringing products to market. BIOVIA Discovery Studio: This life science modeling and simulation application, which is built on the BIOVIA Foundation, enables scientists to engage in scientific exploration from target identification to lead optimization using a wealth of trusted life science modeling and simulation tools. BIOVIA Materials Studio: This materials modeling and simulation application, now also integrated with the BIOVIA Foundation, enables researchers in materials science and chemistry to predict and understand the relationships of a material s atomic and molecular structure with its properties and behavior. Data Management and Informatics BIOVIA is also a leading provider of software-based solutions designed to capture, store, manage and mine scientific data and information, both on premises and in the Cloud. Through this combined portfolio, we provide comprehensive data visualization and analysis software enabling scientists to search, retrieve and use chemical structures, biological and chemical data, experiment data, registration information and more. BIOVIA Insight: This next-generation Life Sciences informatics solution for interactive searching, browsing and visualizing data lets scientists filter data and results by scientifically relevant criteria, accelerating query refinement across a broad range of scientific objects. With increased insight into their data, scientists can make fast, informed decisions about how to move research projects forward. BIOVIA Registration: A flexible, fully featured, out-ofthe-box solution for building, managing, and searching a corporate substance and batch database and for defining, registering, querying, and reporting on biological entities. BIOVIA Chemical Content Databases: This comprehensive, integrated and cross-referenced collection of factual databases and reference works covers chemical sourcing, molecular properties and bioactivity (metabolism and

3 toxicology) information. These resources can be accessed through ELN, data management and informatics applications or via the Internet through the DiscoveryGate portal. BIOVIA ScienceCloud: With no software to manage and no hardware to maintain, this technologically innovative information management and collaboration workspace in the Cloud enhances operational excellence and collaborative discovery for globally networked drug research partners. Unified Lab Management The following BIOVIA software solutions support rapid process development, optimization, validation and scale-up all the way to highly efficient process execution for manufacturing and product commercialization, connecting lab-to-plant workflows and information across the innovation and commercialization lifecycle. BIOVIA Workbook: BIOVIA Workbook is a multi-disciplinary electronic lab notebook (ELN) for documenting and managing the flow of information, tasks and materials within and between labs. BIOVIA Workbook includes strong integration capabilities and workflow support in addition to authoring, collaboration and IP protection capabilities. The notebook offers scientists across multiple disciplines the opportunity to streamline experiment planning, design, execution, analysis and reporting, particularly in regulated environments. BIOVIA Notebook: BIOVIA Notebook is an easy-to-deploy, easy-to-use ELN for organizations focused on intellectual property capture and information sharing, process documentation and overall lower total cost of ownership. It is offered as both an enterprise level, on-premises, serverbased installation and via a SaaS model targeted for smalland medium-sized businesses and academic markets. BIOVIA Laboratory Execution System (LES): An electronic environment for procedure execution in the laboratory, removing paper processes and automating the interaction with methods, instruments and supplies that scientists and analysts use every day in regulated environments. BIOVIA Electronic Batch Records (EBR): An out-of-thebox system that automates the execution and review of batch records. BIOVIA EBR improves regulatory compliance for smaller organizations or sites while avoiding the large overhead of a complex Manufacturing Execution System. BIOVIA Laboratory Information Management System (LIMS): BIOVIA s process- and execution-driven approach to LIMS deployments is fundamentally different from the sample-driven approach of traditional LIMS and eliminates the complexities, excessive customization and lengthy associated validation requirements inherent with legacy LIMS. Applications include: environmental monitoring, inventory management, instrument metrology/calibration management, sample management, stability management and work request management. BIOVIA Experiment Knowledge Base (EKB): Designed specifically for research and development, BIOVIA Experiment Knowledge Base enables scientists to efficiently plan and execute experiments, record and analyze data with powerful queries and visualization, generate flexible reports and rapidly mine knowledge from experiments and data from almost any source. The EKB software provides interoperability with existing lab equipment and applications and offers features for improving experimentation management and collaboration. BIOVIA CISPro: Offered as both an on-premises and a Cloud-based solution, the BIOVIA CISPro Chemical Inventory Management System makes current, real-time chemical safety and inventory data available on-demand, helping to drive safe chemical handling, storage and management. This EH&S compliance software helps companies adhere to federal, state and regional regulatory and safety requirements, supporting the sustainability initiatives of customers in almost every industry. Process Production Operations Process Production Operations software from BIOVIA drives improved quality and process robustness through product and process monitoring and continued process verification (CPV) to improve quality and lower compliance costs. BIOVIA Discoverant: This solution provides process development, quality, and manufacturing specialists with self-service, on-demand access to process and quality data from disparate databases and paper records. The software automatically aggregates and contextualizes the data, enabling ad hoc statistical investigations with automated validation-ready workflows for teams across different organizations. Improved visibility into process data improves overall process understanding. Quality and Regulatory Management Available as SaaS, private Cloud or on-premises deployments, BIOVIA s comprehensive document and process management capabilities scale to thousands of users and millions of documents, while supporting externalized collaboration with third parties and partner communities. BIOVIA QUMAS EDMS: Electronic Document Management (EDM) applications with related R&D submission and QA documentation packages deliver proven regulatory compliance practices for document control and related training across the business. Based on customer and industry requirements and best practices, these BIOVIA QUMAS EDM applications eliminate the cost and complexity of managing paper-based as well as disparate or legacy process management applications. BIOVIA QUMAS Process Management: By centralizing the management of all regulatory content and the associated change control processes, companies can consistently enforce standards across multiple locations. BIOVIA QUMAS s Process Management suite manages a wide variety of processes including: audits, IT change control, event tracking and resolution, license and registrations tracking, CAPAs (corrective actions/preventive actions), quality checks, customer complaints and many others.

4 DELIVERING SCIENTIFIC INNOVATION IN THE AGE OF EXPERIENCE Dassault Systèmes signed a definitive merger agreement to acquire Accelrys on January 30, 2014 with an all-cash tender offer for all of the outstanding shares of Accelrys common stock. The tender offer process was completed on April 29, 2014 with Accelrys filing the Certification and Notice of Termination of Registration with the SEC on May 9, meaning Accelrys is no longer a publicly traded company. Dassault Systèmes announced the creation of BIOVIA on May 21, 2014, describing the new company as a combination of Dassault Systèmes own activities in BioIntelligence, its collaborative 3DEXPERIENCE technologies and the leading life sciences and material sciences applications resulting from the acquisition of Accelrys. In today s experience economy, the capability to develop, simulate and produce breakthrough experiences at the molecular level delivers transformational value for enterprises of all industries, and has the promise to provide exponential value to consumers. BIOVIA is committed to enhancing and speeding innovation, improving productivity and compliance, reducing costs and accelerating product development from discovery through manufacturing for science- and processdriven enterprises of all industries. Integrating BIOVIA s strong suite of scientific informatics solutions with Dassault Systèmes 3DEXPERIENCE Platform will create significant opportunities for BIOVIA to support and develop systemic collaboration, project management, data and content reuse, traceability and other processes, applications and integrations that are absolutely critical to science- and process-driven industries. COMPANY BACKGROUND AND HISTORY Accelrys was founded in 2001 from the combination of five companies: Molecular Simulations Inc. (MSI, itself a result of the combination of Biodesign, Cambridge Molecular Design, Polygen and, later, Biocad and Biosym Technologies), Synopsys Scientific Systems, Oxford Molecular, the Genetics Computer Group (GCG), and Synomics Ltd. In 2004, Accelrys acquired SciTegic, the developer of Pipeline Pilot data pipelining and scientific workflow authoring software. In July 2010, Accelrys merged with Symyx Technologies, Inc. This merger combined the Accelrys portfolio of scientific informatics solutions with the market-leading Symyx electronic laboratory notebook (ELN), now BIOVIA Workbook. The Symyx ELN had developed from Symyx s acquisition of two ELN companies, IntelliChem, Inc. and Synthematix, Inc., in The Accelrys-Symyx merger also extended Accelrys product offerings with certain software and content products from MDL Information Systems, Inc., which Symyx had acquired from Elsevier, Inc. in This acquisition included software products such as MDL Notebook, ISIS and its successor Isentris data access, analysis and decision support system, as well as the Direct data cartridge, Draw chemical drawing tool and comprehensive bioactivity and chemical sourcing databases including the well-known Available Chemicals Directory (ACD). MDL had been a premier scientific software vendor for over 25 years with critical software solutions deployed across approximately 750 organizations. Subsequently, Accelrys extended its ELN capabilities through the acquisition of Contur Software AB in May The Contur ELN, now BIOVIA Notebook, improves information sharing and reuse, data protection, process documentation and overall productivity in paperless environments with rapidly deployable on-premises and Cloud deployment options. Accelrys broadened its process management and compliance capabilities through the acquisition of VelQuest Corporation in January VelQuest s industry-leading data capture and laboratory execution software extends notebook usability into the critical QA/QC phase of product development in Good Manufacturing Practices (GMP) environments. Accelrys further expanded its capabilities in new product development and commercial manufacturing and quality operations through the acquisition of Colorado-based Aegis Analytical Corporation in October 2012 with its industryleading Discoverant operations intelligence solution for compliance-intensive industries. In January of 2013 Accelrys solidified its market leadership in the laboratory informatics space with the acquisition of Vialis AG, a leading informatics system integrator based in Liestal, Switzerland serving the pharmaceutical, biotechnology, chemicals and agro-science industries. This team offers professional consulting services in business analysis, laboratory process excellence, multi-moment analysis, business case justification, vendor solution selection, integration consulting and solution support across the entire value and knowledge creation chain from research to production. In September 2013, Accelrys acquired ChemSW, Inc., a leading Environmental Health & Safety (EH&S) compliance solutions provider. This acquisition enabled Accelrys to provide CISPro solutions for managing and tracking the source, use and disposal of chemicals along the entire lab-to-plant value chain. The ability to manage chemicals across the full product lifecycle helps organizations across industries enhance compliance with increasingly complex global, national and local environmental health and safety regulations, and is critical to advancing sustainability strategies. In December 2013 Accelrys acquired QUMAS, a Cork Ireland-based company that focuses on controlled document management. This acquisition added targeted governance, risk management and compliance solutions to Accelrys portfolio, positioning Accelrys to deliver comprehensive enterprise quality management offerings. QUMAS customers include approximately 250 life sciences companies including manufacturers and clinical contract research organizations. Accelrys deliberate merger and acquisition strategy made the company one of the largest, most comprehensive scientific informatics companies in the world with a clear focus on creating, driving and delivering comprehensive scientific product lifecycle management solutions across the research, development, QA/QC and manufacturing phases of product development.

5 COMPANY LOCATIONS BIOVIA global headquarters is located in San Diego CA. The company currently employs approximately 750 people in software development, quality assurance, customer support, consulting, sales, marketing, accounting, finance and legal. Corporate Headquarters BIOVIA, Inc Wateridge Vista Drive, San Diego, CA 92121, Tel: Fax: European Headquarters BIOVIA Limited Registered office: 334 Cambridge Science Park, Cambridge CB4 0WN Registered in England: Tel: Fax: Asia Headquarters BIOVIA KK Kasumigaseki Tokyu Bldg 17F 3-7-1, Kasumigaseki, Chiyoda-ku, Tokyo, , Japan Tel: Fax: Bangalore, India Dassault Systèmes India Private Limited, The Leela Galleria, Commercial Block, 7th Floor, No. 23, Old Airport Road, Bangalore , India. Telephone: Fax : Basel, Switzerland Aeschenvorstadt Basel Switzerland Tel: Fax.: Bedminster, New Jersey, 135 US Highway 202/206, 1 FL Bedminster, NJ Tel: Fax: Bend, Oregon, 755 SW Bonnett Way, Suite 2100 Bend, OR Tel: Fax: Boulder, Colorado, 1380 Forest Park Circle Suite 200 Lafayette, CO Tel: Fax: Boston, 200 Wheeler Road South Tower, 2nd Floor Burlington, MA , Tel: Fax: Durham, North Carolina, 2511 Old Cornwallis Rd., Ste 280 Durham, NC Tel: Milford, Massachusetts, #9 Industrial Rd. Suite 4 Milford, MA Tel: Paris, France Parc Club Orsay Université 20, Rue Jean Rostand, Orsay Cedex France Tel: Fax: Pleasant Hill, California, 3480 Buskirk Avenue, Suite 300 Pleasant Hill, CA Tel: Fax: Seoul, Korea Sampyeong-dong, Korea BioPark Bldg C-602, Bundang-gu, Seongnam-si, Gyeonggi-do, , Korea Tel: Fax: Singapore 80 Robinson Rd. #02-00 Singapore Stockholm, Sweden Birger Jarlsgatan 33, 2 tr Stockholm Sweden Tel: Fax: Cork, Ireland Cleve Business Park Monahan Road, Cork Ireland Tel: Fax: Cologne, Germany Hohenzollernring 84 D Cologne Germany

6 Our 3DEXPERIENCE platform powers our brand applications, serving 12 industries, and provides a rich portfolio of industry solution experiences. Dassault Systèmes, the 3DEXPERIENCE Company, provides business and people with virtual universes to imagine sustainable innovations. Its world-leading solutions transform the way products are designed, produced, and supported. Dassault Systèmes collaborative solutions foster social innovation, expanding possibilities for the virtual world to improve the real world. The group brings value to over 190,000 customers of all sizes in all industries in more than 140 countries. For more information, visit Dassault Systèmes. All rights reserved. 3DEXPERIENCE, the Compass icon and the 3DS logo, CATIA, SOLIDWORKS, ENOVIA, DELMIA, SIMULIA, GEOVIA, EXALEAD, 3D VIA, 3DSWYM, BIOVIA, NETVIBES, and 3DEXCITE are commercial trademarks or registered trademarks of Dassault Systèmes or its subsidiaries in the U.S. and/or other countries. All other trademarks are owned by their respective owners. Use of any Dassault Systèmes or its subsidiaries trademarks is subject to their express written approval. Dassault Systèmes Corporate Dassault Systèmes 175 Wyman Street Waltham, Massachusetts BIOVIA Corporate Americas BIOVIA 5005 Wateridge Vista Drive, San Diego, CA BIOVIA Corporate Europe BIOVIA 334 Cambridge Science Park, Cambridge CB4 0WN England DS

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