Northern Illinois. proton therapy facility

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1 Northern Illinois proton therapy facility February, 2007

2 Northern Illinois proton therapy facility 2 Projected 16-State Service Area The Need Scale Legend Potential service region Existing proton therapy centers In Development proton therapy centers Northern Illinois proton therapy facility Potential Patient Population Total population in 16-state service region: 69,305,256 Total cancer cases eligible for radiation therapy: 377,714 Radiation cases eligible for proton therapy (15%): 56,657 Annual capacity of Northern Illinois proton center: 1,500

3 Northern Illinois proton therapy facility 3 What is Proton Therapy? The Treatment The most precise form of radiation treatment available. Proton therapy radiates primarily the tumor site, leaving surrounding healthy tissue and organs intact and unharmed. Non-invasive and painless. Proton therapy maintains quality of lifestyle during the treatment process on an out-patient basis. Minimal side effects. Highly effective treatment for tumors in the head, brain, neck, lung and prostate. Proton therapy is often used in conjunction with other cancer treatment modalities. Quickly becoming radiation therapy of choice for pediatric cancers. Duration of Treatment A typical patient is treated for minutes once a day over five to eight weeks, on an out-patient basis. Proton Therapy Is Used to Treat Many Cancers Uveal Melanoma (eye) Skull-base Sarcomas (head) Meningiomas (brain) Paranasal Sinus Carcinoma (sinus/nasal) Nasopharyngeal Carcinoma (throat) Pediatric Malignancy Paraspinal Tumors (spinal) Prostate Craniopharyngioma (brain) Acoustic Neuromas (ear) Large AVM (brain) Pituitary - functioning, retreatment (brain) Metastases selected Gliomas - selected, boosts (brain) Proton Therapy Shows Promise in Other Areas Breast irradiation Lung Rectal carcinoma Advanced gynecological disease

4 Northern Illinois proton therapy facility 4 How It Works The Treatment Protons deposit their radiation differently than X-rays. Compared to an X-ray beam, a proton beam has a low entrance dose, a high dose designed to cover the entire tumor, and no exit dose beyond the tumor. The point where the highest energy release occurs is called the Bragg peak. The Bragg Peak Dose (arb units) Depth in Tissue (cm) Images courtesy of M.D. Anderson The Clinical Benefits of Proton Cancer Therapy Precise targeting unique to charged particles Radio-surgical precision Reproducible treatments Fewer acute and chronic side effects Increased dosage possible Reduced normal tissue damage Decreased risk of radiation-induced tumors (important to pediatric oncology)

5 Northern Illinois proton therapy facility 5 Facility and Site Plans The Facility 15-to-20-acre site contiguous to northern boundary with Fermilab - 11-to-13-acres for building & grounds - additional land for future patient/family lodging facility 100,000 square feet 4 separate treatment rooms 1 dedicated research room 2 gantries (190 tons each) 2 fixed-beam rooms 1 eye beam room for ophthalmological treatment $120 million cost shared by - federal government - state government - private investors Images provided by BSA LifeStructures

6 Northern Illinois proton therapy facility 6 Equipment The Facility An accelerator In this case, a synchrotron, the heart of the acceleration process, contains a ring of magnets that restricts protons on a set path inside the high vacuum chamber. After many cycles through the chamber, the protons reach the energy required by a specific treatment plan and are extracted from the ring into the beam transport line, which then directs the proton beam to the patient in a treatment room. Photo courtesy of F. Carter Smith, FCS Photos Beam delivery to the gantries The facility includes rotating gantries and fixed beam rooms. Each three-story 200-ton steel gantry revolves 360 degrees around a patient so the proton beam can be delivered at any angle. In the fixed beam rooms, the patient is seated in a special chair or couch which is moved around the beam to a precise position. Inside the gantry The proton delivery system is positioned to place the beam exactly in the tumor. The patient feels nothing during the treatment. isocentric gantry Photo courtesy of F. Carter Smith, FCS Photos

7 Northern Illinois proton therapy facility 7 Proposed Site Location The Facility DuPage County Airport 38 DuPage National Technology Park Fabyan Pkwy Farnsworth Ave Fermilab 88 Fabyan Pkwy Cornerstone Architects Existing U.S. Proton Therapy Centers Loma Linda University Medical Center, southern California Midwest Proton Radiotherapy Institute at Indiana University, Bloomington M.D. Anderson Cancer Center s Proton Center, Houston, Texas Francis H. Burr Proton Therapy Center at Massachusetts General Hospital, Boston The University of Florida Proton Therapy Institute, Jacksonville

8 Northern Illinois proton therapy facility 8 Clinical The Partners Illinois Medical Centers Regional Proton Treatment Facilities Hospital Systems Oncology Physicians Research Illinois Medical Schools Research Universities International and National Proton Treatment Facilities Education Illinois Medical Schools Universities Community Colleges in northern Illinois region International and National Proton Treatment Facilities The Timeline Begin architectural planning Groundbreaking Start installing equipment Begin treatment The Funding Project Cost Federal Support (FY08 - FY11) State Support (FY08 - FY11) Private Equity, NIU Bonding $120 Million $20 million $20 million $80 million

9 Northern Illinois proton therapy facility 9 The Economic Impacts Construction Start-up Operation Full Operation Employment Employee compensation $39 million over $2.2 million over $6.5 million Gross County Product $53 million over $2.8 million over $8.8 million The NIU Connection Northern Illinois University has a nationally-recognized program of long-standing in the area of accelerator physics: - NIU physicists helped discover elusive top quark in NIU took over Fermilab neutron therapy program in 2004; fixed beam accelerator used to treat several rare types of cancer. - NIU chosen to develop next generation of particle accelerators in partnership with Fermi and Argonne; awarded $6.2 million to create and run Northern Illinois Center for Accelerator and Detector Development (NICADD). Of the many spin-offs from particle physics research, none are as promising as those in medicine particularly cancer treatment. NIU s physics program has strong emphasis in medical physics, with new degrees and emphases currently under development. Strong programs in allied health areas further complement NIU offerings in particle therapy. Nursing, counseling, physical therapy, nutrition and speech/language/hearing programs are all developing new degrees and emphases in oncology. NIU s College of Engineering and Engineering Technology is working on new programs in medical engineering the creation, maintenance and operation of new, cutting-edge medical devices and machines used in advanced cancer treatment and rehabilitation. The College of Education and several other NIU colleges involved in teacher preparation are developing special tutoring and education programs for pediatric cancer patients. No other proton therapy treatment center provides this extent of layered services for patients and families. Dedicated research space and access to accelerator beam provide extensive research opportunities in physics, chemistry, biology, engineering and all of the allied health areas; also expanded educational opportunities for students.

10 Radiation Oncology Physicians with Expertise in Proton Therapy in Illinois and Midwest Allan F. Thornton, M.D. Medical Director Midwest Proton Radiotherapy Institute at Indiana University/Bloomington Primary Phone Contact: Having devoted his career to addressing the health care needs of patients with potentially lifethreatening cancers, Dr. Thornton s work currently focuses on the benefits of proton therapy in extending life and health. As Medical Director of the Midwest Proton Radiotherapy Institute, he is working with physicians and researchers, other proton therapy centers and healthcare organizations in research trials and clinical protocols to explore models of proton therapy care and treatment. MaryAnne Marymont, M.D. Children s Memorial Hospital, Chicago Director of Pediatric Radiation Oncology Assistant Professor of Clinical Radiology, Northwestern University s Feinberg School of Medicine Primary Phone Contact: Nuclear Oncology, S.C. Alexander Phillips, M.D. (Chairman) K. Saroja, M.D. Dennis Galinsky, M.D. R. Bendre, M.D West Ogden Ave Berwyn, IL Primary Phone Contact: In practice at DuPage Oncology Center (Winfield), NOMC/MacNeal Radiation Therapy-Berwyn Radiation Oncology Center, North Shore Radiation Oncology Center (Skokie) and Raymond G. Scott Cancer Care Center (Geneva) Midwest Radiation Oncology Consultants, Ltd. Terrence J. Bugno, M.D., FACR Geoffrey L. Smoron, M.D., FACR 77 North Airlite Elgin, IL Primary Phone Contact: In practice at Centegra Sage Cancer Center, Northern Illinois Medical Center (McHenry) and Regional Cancer Care Center at St. Joseph Hospital (Elgin)

11 Radiation Oncology Physicians with Expertise in Proton Therapy in Illinois and Midwest (continued) Ross A. Abrams, M.D. Radiation Oncology Department Rush University Medical Center Primary Phone Contact: Robert T. Woodburn, III, M.D. Radiation Oncologist Cancer Treatment Group Oncology Institute of Methodist Hospital Merrillville, Indiana Primary Phone Contact: Philip Connell, M.D. Assistant Professor of Radiation & Cellular Oncology Department of Radiation Oncology The University of Chicago Hospitals Primary Phone Contact: Patrick W. McLaughlin, M.D. Professor & Chief, Department of Radiation Oncology University of Michigan Health Systems Primary Phone Contact: Bharat B. Mittal M.D. FACR Professor & Chairman Radiation Oncology Northwestern University / Northwestern Memorial Hospital Primary Phone Contact: Stewart Goldmann, M.D. Medical Director, Neuro-oncology Gus Foundation Chair of Neuro-oncology Children s Memorial Hospital

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