Preliminary Program. strokeconference.org. Education. Inspiration. Illumination.

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1 Preliminary Program Nursing Symposium: February 23 Sessions: February Exhibits: February San Antonio, Texas strokeconference.org Education. Inspiration. Illumination.

2 State-of-the-Art Stroke Nursing Symposium Tuesday, Feb. 23 The American Heart Association/American Stroke Association is grateful to the members of the State-of-the-Art Stroke Nursing Symposium 2010 Program Committee for their dedication and leadership provided throughout the year planning the program. Program Committee Rosemarie King, RN, PhD, FAHA, Co-Chair Debbie Summers, RN, MSN, FAHA, ARNP, Co-Chair Tamilyn Bakas, DNS, RN, FAHA, FAAN Terrie Black, MBA, BSN, RN, BC, CRRN Jennifer Cohn, MS, BSN, MSN Lisa Davis, MSN, RN, CCRC Wende Fedder, RN, BSN, MBA, FAHA Sharon Ostwald, PhD, RN Sue Wehner, PhD, RN, MSN, NP (ISC Program Committee Liaison) For a list of the Nursing Symposium abstract graders, please go to strokeconference.org, State-of-the-Art Stroke Nursing Symposium page. For Registration and Housing information, please go to strokeconference.org, Registration and Housing page. Please note that there is a separate registration fee to attend the Nursing Symposium. Symposium Description The State-of-the-Art Stroke Nursing Symposium is a forum designed to provide the most current information to nursing and other healthcare professionals who treat patients and families in all phases of stroke treatment from the emergency department through rehabilitation. The symposium will update and inform the audience about nursing issues along the continuum of stroke care (ischemic and hemorrhagic stroke management, rehabilitation and stroke program development.) The goal of the program is to share innovative best clinical practices that have been developed to optimize patient outcomes throughout the stroke continuum of care. A plenary program and break-out sessions are planned to meet the educational needs for nurses and healthcare professionals at various levels of skill. Learning Objectives 1. Compare and contrast the difference in stroke symptoms between women and men 2. Explain the stroke systems of care networking: metro vs. rural; telemedicine vs. telephone 3. Describe hypothermia including its pathophysiology 4. Utilize advanced stroke concepts to: a. Translate clinical research into clinical practice b. Assess clinical trials c. Analyze case studies in research-based endovascular treatment of acute ischemic stroke and nursing implications 5. Summarize the essentials of standard clinical practice and stroke center development including: a. Neurovascular anatomy and pathophysiology for nursing practice b. Primary and secondary stroke prevention: teaching concepts c. Stroke center recertification 6. Analyze rehabilitation and recovery components including: a. Bio markers and depression b. Avoiding medicare denials c. Evidence of the value of today s virtual presence for caregivers 7. Create an individualized professional development plan to include: a. Writing an abstract b. Preparing a poster c. Publishing an article Continuing Education Accreditation Nurses Please visit strokeconference.org, CME/CE link under Online Tools for information regarding CE credit. Register Today strokeconference.org

3 Nursing Symposium Program Tuesday, Feb. 23 8:30 am 5:30 pm 8:30 am 12:05 pm Plenary Session Moderators: Rosemarie King, RN, PhD, FAHA, Chicago, IL Debbie R Summers, MSN, RN, CNRN, CCRN, FAHA, Kansas City, MO Opening Remarks Sandra Dunbar, RN, FAHA, FAAN, Atlanta, GA Program Announcements Tamilyn Bakas, RN, FAHA, Indianapolis, IN Council Award Presentation Stroke Symptoms: Comparing Women With Men Lynda Lisabeth, PhD, FAHA, Ann Arbor, MI Stroke Systems of Care Networking: Metro vs. Rural and Telemedicine vs. Telephone Phillip Scott, MD, FAHA, Ann Arbor, MI Session 10:20 am 10:40 am Hypothermia Pathophysiology Nicole R Gonzales, MD, Houston, TX Hypothermia: A Nursing Perspective Karen Rapp, RN, La Jolla, CA Session 12:05 pm 1:30 pm Lunch 1:30 pm 5:30 pm Concurrent A Advanced Stroke Concepts: Topics in Clinical Research and Practice Moderator: Susan E Wehner, PhD, RN, MSN,NP, Lansing, MI Translating Clinical Research into Monday Morning Clinical Practice Nicol Korner-Bitensky, OTR, PhD, DDO, Quebec, Canada Update on Clinical Trials Lisa Davis, MSN, RN, CCRC, Bethesda, MD 3:15 pm 3:45 pm Case Studies in Research-Based Endovascular Treatment of Acute Ischemic Stroke and Nursing Implications Jennifer Cohn, RN, MSN, CCRN, Indianapolis, IN Session 1:30 pm 5:30 pm Concurrent B Essentials of Standard Clinical Practice and Stroke Center Development Moderator: Debbie R Summers, MSN, RN, CNRN, CCRN, FAHA, Kansas City, MO Neurovascular Anatomy and Pathophysiology for Nursing Practice Linda R Littlejohns, RN, MSN, CCRN, CNRN, San Juan Capistrano, CA Primary and Secondary Stroke Prevention: Teaching Concepts Bernadette Boden-Albala, MPH, DrPH, New York, NY 3:15 pm 3:45 pm Stroke Center Recertification Lori M Massaro, MSN, CRNP, Pittsburgh, PA Session 1:30 pm 5:30 pm Concurrent C Rehabilitation and Recovery: An Ongoing Process Moderator: Rosemarie King, RN, PhD, FAHA, Chicago, IL Bio Markers and Depression Pamela H Mitchell, RN, Seattle, WA Avoiding Medicare Denials: Documenting Evidence of Nursing Care Terrie Black, MBA, BSN, RN, BC, CRRN, Williamsville, NY 3:15 pm 3:45 pm Being There for Caregivers: Evidence of the Value of Today s Virtual Presence Linda L Pierce, PhD, RN, CNS, CRRN, FAHA, Toledo, OH Session 1:30 pm 5:30 pm Concurrent D Professional Development Please note this session is limited to 45 participants only. Moderator: Tamilyn Bakas, DNS, RN, FAHA, FAAN, Indianapolis, IN Writing an Abstract Tamilyn Bakas, DNS, RN, FAHA, FAAN, Indianapolis, IN Preparing a Poster Sharon K Ostwald, PhD, RN, FGSA, Houston, TX Publishing Elaine T Miller, DNS, RN, CRRN, FAHA, FAAN, Cincinnati, OH Individual and Group Mentoring Roundtables Table Monitors: Tamilyn Bakas, DNS, RN, FAHA, FAAN, Indianapolis, IN Patricia Clark, PhD, RN, FAHA, Atlanta, GA Barbara Lutz, RN, PhD, CRRN, Gainesville, FL Elaine T Miller, DNS, RN, CRRN, FAHA, FAAN, Cincinnati, OH Sharon K Ostwald, PhD, RN, FGSA, Houston, TX 3:15 pm 3:45 pm Individual and Group Mentoring Roundtables (cont.) Session

4 Stroke Journal Pre-conference Symposium As Stroke Turns 40 Committing to a Stroke Global Action Plan Monday, Feb. 22 and Tuesday, Feb. 23 This pre-conference symposium is being organized by the Stroke journal in celebration of the Stroke journal s 40th anniversary. This synergium * will devise and rank new ways of accelerating progress in stroke treatment, rehabilitation and prevention by innovations, partnerships and synergies and committing the major stroke organizations to a global, prioritized and unbiased action plan. * Synergium: A forum for working synergistically together. Please note that there is a separate registration fee to attend this pre-conference symposium. Monday, Feb. 22 4:30 pm 9:00 pm Reception/Buffet Dinner Welcome and Commitment What Lessons Have We Learned in the Past 40 Years? Henry JM Barnett, Mark Dyken A Cardiologist Looks at Stroke Valentin Fuster Opportunities in the Changing Worlds of Academia, Industry and Government Allen Roses Tuesday, Feb. 23 7:00 am 5:30 pm Continental Breakfast Background and Overview of the Day s Program Vladimir Hachinski Meeting of the Individual Working Groups: 1. Basic Science, Drug Development and Technology: Opportunities and Imperatives for Translational Research 2. Acute Stroke Management: Applying and Expanding What We Know 3. Stroke Prevention: Broadening Our Approach and Intensifying Our Efforts 4. Brain Recovery and Rehabilitation: Harnessing the Regenerative Powers of the Brain and the Individual 5. Into the 21st Century. The Web, Technology and Communications: New Tools for Progress 6. Opportunities for Partnerships, Patients, Organizations, Communities, Government, Industry and Academia 7. Educating and Energizing Professionals, Patients, the Public and Policy Makers 10:20 am 11:00 am Round-Robin of all seven Working Groups 12:00 pm 1:00 pm Lunch (Chairs update their presentations in light of the round-robin.) Presentations by Each Group 3:00 pm 3:20 pm General Final Recommendations Summing Up Vladimir Hachinski Closing Remarks Ralph Sacco, President Elect, American Heart Association Support and Funding Financial support for the symposium is provided by: American Heart Association/American Stroke Association World Federation of Neurology World Stroke Organization European Stroke Organization European Stroke Conference Canadian Stroke Network Heart & Stroke Foundation Centre for Stroke Recovery Lippincott Williams & Wilkins International Stroke Conference 2010 C A L L F O R S C I E N C E Submit Abstracts Late-Breaking Science and Ongoing Clinical Trials Abstracts Submission opens: Oct. 5, 2009, 8:00 am CDT* Deadline: Nov. 2, 2009, 5:00 pm CST *Each submission must include a non-refundable $30 (US) online payment. Visit strokeconference.org, Submit Late-Breaking/Ongoing Clinical Trials page for criteria and further information. Science and Technology Hall (Exhibits) Wednesday and Thursday, Feb , 12:00 noon 6:30 pm For further information on Exhibits, please go to strokeconference.org, Exhibits page.

5 ISC Program Information The American Heart Association/American Stroke Association is grateful to the members of the ISC 2010 Program Committee for their dedication and leadership provided throughout the year in planning the program. Program Committee Patricia D Hurn, PhD, FAHA, Chair Lewis B Morgenstern, MD, FAHA, Vice Chair Andrei Alexandrov, MD Kyra Becker, MD Cheryl Bushnell, MD, MHS, FAHA Colin Derdeyn, MD, FAHA Alexander Dromerick, MD, FAHA Pamela Duncan, PhD, PT, FAHA Frank M Faraci, PhD, FAHA Larry Goldstein, MD, FAAN, FAHA Steven Greenberg, MD, PhD Philip B Gorelick, MD, MPH, FACP, FAHA, Past Chair Murat Gunel, MD, FACS Brian Hoh, MD Rebecca Ichord, MD David F Kallmes, MD Italo Linfante, MD Louise D McCullough, MD Pearse Morris, MD Bruce Ovbiagele, MD, FAHA Miguel A Perez-Pinzon, PhD Gustavo C Roman, MD, FACP Phillip A Scott, MD, FAHA Sue Wehner, PhD, RN, MSN, NP Lawrence Wong, MD, FAHA Gregory J Zipfel, MD Program Description This 2½-day conference provides a forum in which to present recent scientific work related to stroke and cerebrovascular disease. More than 900 abstract presentations, lectures and debates will be featured. This year, special symposia and debates will focus on numerous topics including: brain repair after stroke; state-of-the-art surgical and endovascular treatment for intracranial occlusive disease; the economics of stroke (debate); subarachnoid hemorrhage: current protocols and future prospective; new approaches to the decision to anticoagulate; vascular cognitive impairment and Alzheimer Disease; HIV and cerebrovascular disease; comprehensive stroke centers: the future of stroke care; informed consent: have we gone too far or not far enough? (debate); controversies in the management of cerebral arteriovenous malformations: where we are and can ARUBA help? (debate); and emerging new mechanisms for ionic imbalance and cell death in ischemic brain damage. Sessions in clinical categories will center on diagnosis, acute management, in-hospital treatment, rehabilitation and recovery, pediatric stroke, prevention, community/risk factors, nursing, emergency medicine, outcomes and vascular cognitive impairment. Sessions in surgical and interventional categories will focus on aneurysm, carotid revascularization, intracranial atherosclerotic occlusive disease, ischemic stroke intervention, SAH management and vascular malformations. Target Audience/Program Objectives The conference provides an educational experience for neurologists, neurosurgeons, neurointerventionalists, neuroradiologists, endovascular specialists, physiatrists, emergency medicine specialists, nurses, pharmacists, allied health professionals and basic researchers in the major fields of cerebrovascular disease and stroke: experimental models and translational research, physiology, pathology, diagnosis, treatment, prevention and rehabilitation. At the conclusion of the conference, learners should be able to: Examine recent advances in basic models of stroke and translational research Evaluate recent advances in the diagnosis, treatment, prevention and rehabilitation of stroke and cerebrovascular disease Analyze new and ongoing clinical research advances through late-breaking science and ongoing clinical trials sessions Create a forum for the exchange of new research, treatment and intervention by scientists and investigators working in all areas of stroke and cerebrovascular disease Learning Objectives After attending the International Stroke Conference, participants will be able to: Describe the most recent stroke clinical trials that may impact the specialties of stroke care Interpret neurovascular treatments and interventions that are new in stroke care Appraise key findings in translational and clinical stroke research Compare and contrast stroke in women, children and minorities Debate epigenetics and stroke prevention Assess stroke systems of care networking through technology Summarize novel areas of clinical and experimental stroke recovery and rehabilitation CME/CE Disclosure All faculty participating in CME/CE activities sponsored by the American Heart Association /American Stroke Association will disclose to the audience (1) significant financial relationships with the manufacturer(s) of products from the commercial supporter(s) and/or the manufacturer(s) of products or devices discussed in their presentation and (2) unlabeled/unapproved uses of drugs or devices discussed in their presentation. Such disclosures will be made in writing in the course presentation materials. Continuing Education Accreditation Physicians, physician assistants, nurses and pharmacists may earn continuing education credits. For full CME/CE accreditation information on the International Stroke Conference, please visit strokeconference.org, CME/CE link under Online Tools. Legal Disclaimer The International Stroke Conference is a scientific and educational meeting for the purpose of exchanging and discussing research results and scientific developments in the field of cerebrovascular disease. Accordingly, the American Heart Association/American Stroke Association cannot and does not offer any assurance or warranty of the accuracy, truthfulness or originality of the information presented at the conference.

6 ISC Preliminary Program Please note that sessions are subject to change. For the most current program information, go to strokeconference.org, Program Information page. Wednesday, Feb. 24 7:30 am 9:00 am Brain Repair After Stroke (Basic and Translational Neuroscience of Stroke Recovery) Moderators: Steven C Cramer, MD, Orange, CA Randolph J Nudo, PhD, Kansas City, KS Brain Rewiring After Stroke Randolph J Nudo, PhD, Kansas City, KS Cellular and Molecular Mechanisms of Promoting Stroke Michael Chopp, PhD, Detroit, MI Behavioral Experience and Brain Remodeling After Stroke Theresa A Jones, PhD, Austin, TX Human Studies in Post-stroke Brain Repair Steven C Cramer, MD, Orange, CA Dissections of the Carotid and Vertebral Arteries Revisited (Acute Management) Moderator: Scott E Kasner, MD, MSCE, Philadelphia, PA Advances in the Diagnosis of Dissection: What Is the Best Test? Greg Zaharchuk, MD, PhD, Palo Alto, CA Anti-Thrombotic Therapy for Prevention of Stroke in Dissection: What Is the Evidence? Dimitrios Georgiadis, MD, Zürich, Switzerland When in Doubt, Randomize: The CADISS Trial Hugh Markus, DM, FRCP, London, United Kingdom Is There a Role for Aggressive Endovascular Treatment of Dissection? Alex Abou-Chebl, MD, Louisville, KY HIV and Cerebrovascular Disease (Community/Risk Factors) Moderators: Mitchell Elkind, MD, MS, FAAN, New York, NY Souvik Sen, MD, MS, Chapel Hill, NC Epidemiology of Stroke in HIV-infected Patients Alejandro Rabinstein, MD, ANP, Rochester, MN Neuroimaging for HIV Associated Cerebrovascular Disease William J Powers, MD, Chapel Hill, NC Association of HAART and Cerebrovascular Disease Souvik Sen, MS, MD, Chapel Hill, NC Prevention of Stroke in HIV-infected Patients Mitchell Elkind, MD, MS, FAAN, New York, NY s: Emergency Medicine s: Diagnosis s: Nursing 9:00 am 9:15 am 9:15 am 10:45 am Cutting Edge and Future Treatment of Unruptured Aneurysms (Aneurysm) Moderators: Philip M Meyers, MD, FAHA, New York, NY Cameron G McDougall, MD, Phoenix, AZ Treatments Based on Microsurgical Techniques (Clip Reconstruction, Bypass, Etc) Michael Lawton, MD, San Francisco, CA Embolic Materials in Treatment Saruhan Cekirge, Ankara, Turkey Flow Diversion Techniques Pedro Lylyk, MD, Buenos Aires, Argentina Biology and Genetics Based Treatments Murat Gunel, MD, New Haven, CT Are We Ready Now for a New Definition for Cerebrovascular Disease? (Diagnosis) Moderators: Lawrence Wong, MD, Shatin, Hong Kong Louis R Caplan, MD, Boston, MA Historical Perspective on Defining the Categories of Cerebrovascular Disease Louis R Caplan, MD, Boston, MA The New Definition of Transient Ischemic Attack Gregory W Albers, MD, Palo Alto, CA The New Definition of Cerebral Infarction Jeffrey L Saver, MD, FAHA, FAAN, Los Angeles, CA The New Definition of Stroke Scott E Kasner, MD, MSCE, Philadelphia, PA Whole Genome Association Studies in Stroke: Collaboration and the American Stroke Association-Bugher Foundation Centers for Stroke Prevention Model (Community/Risk Factors) Moderators: Karen L Furie, MD, MPH, FAHA, Boston, MA Hugh Markus, DM, FRCP, London, United Kingdom Small Vessel-type Intracranial Disease Risk Larry B Goldstein, MD, FAHA, FAAN, Durham, NC Genomics and Genetics of TIAs and Stroke S Claiborne Johnston, MD, FAHA, San Francisco, CA Determinants and Outcomes of WM Hyperintensity Natalia S Rost, MD, MA, Boston, MA Race, Sex and Stroke: What Really Matters? Piero Verro, MD, Sacramento, CA s: Acute Management s: Basic and Translational Neuroscience of Stroke Recovery s: Hemorrhage Intraparenchymal 10:45 am 11:00 am For the most current program information, please visit strokeconference.org, Program Information page.

7 11:00 am 12:30 pm Plenary Session I Moderators: Patricia D Hurn, PhD, FAHA, Portland, OR Lewis B Morgenstern, MD, FAHA, Ann Arbor, MI Conference Opening Patricia D Hurn, PhD, FAHA, Portland, OR American Heart Association/American Stroke Association President s Remarks Clyde W Yancy, MD, Dallas, TX Stroke Council Chair s Update on ASA Stroke Public Policy and Advocacy Initiatives Jeffrey L Saver, MD, FAHA, FAAN, Los Angeles, CA Pierre B Fayad, MD, FAHA, Omaha, NE Thomas Willis Lecture Siekert and Globus Award Presentations Stroke Care in Emergency Medicine Award Presentation William M Feinberg Award for Excellence in Clinical Stroke 12:30 pm 12:45 pm 12:45 pm 2:00 pm Science and Technology Hall (Exhibits) and Lunch Break Professor-Led Poster Tours by Category Session I: Moderated Q&A with Poster Presenters Nursing and Rehabilitation Professions Luncheon (ticket required; seating is limited) Fellow and Early Career/Stroke Leader Luncheon (ticket required; seating is limited) 2:00 pm 3:30 pm Emerging New Mechanisms for Ionic Imbalance and Cell Death in Ischemic Brain Damage (Experimental Mechanisms and Models) Moderators: Dandan Sun, MD, PhD, Madison, WI Michael Tymianski, MD, PhD, FRCSC, Toronto, ON, Canada NMDA and AMPA Glutamate Receptors in Stroke Michael Tymianski, MD, PhD, FRCSC, Toronto, ON, Canada Acid Sensing Ion Channels: Novel Therapeutic Targets for Ischemic Brain Injury Zhigang Xiong, MD, PhD, Portland, OR NCX1 and NCX3 Knocking Down and Knocking Out Increases Ischemic Brain Damage: Transductional and Transcriptional Implications Lucio Annunziato, MD, Naples, Italy Concerted Role of Na+/H+ Exchanger and Na+/Ca2+ Exchanger in Ischemic Brain Injury Dandan Sun, MD, PhD, Madison, WI Management of Acute Intracerebral Hemorrhage: An Update (Hemorrhage Intraparenchymal) Moderators: Rafael J Tamargo, MD, Baltimore, MD Darin Zahuranec, MD, Ann Arbor, MI Medical Treatment of Acute ICH Craig Anderson, MD, PhD, Sydney, NSW, Australia Surgical Treatment of Acute ICH Joseph Broderick, MD, FAHA, Cincinnati, OH Prognosis and Withdrawal of Technological Support J Claude Hemphill, MD, MS, FAAN, San Francisco, CA Recovery and Prevention of Recurrence Steven M Greenberg, MD, PhD, Boston, MA Physiologic Imaging of Brain Perfusion (Carotid Revascularization) Moderators: Rocco A Armonda, MD, Bethesda, MD Pearse Morris, MD, Winston-Salem, NC Cerebrovascular Perfusion Imaging, CTA, CTP, ASL, BOLD, Cerebrovascular Reserve and Reactivity David Mikulis, MD, Toronto, ON, Canada Intraoperative Cerebral Blood Flow, Emboli and Brain Imaging David A Stump, PhD, Winston Salem, NC What Has PET Taught Us About Cerebrovascular Reserve in EC-IC Bypass? Colin Derdeyn, MD, FAHA, St Louis, MO Advanced MRI Techniques for MRI Evaluation of Perfusion Gil Gonzalez, MD, PhD, Boston, MA s: Pediatric Stroke s: Preventive Strategies s: Vascular Cognitive Imapirment 3:30 pm 4:00 pm Break/Science and Technology Hall (Exhibits)

8 ISC Preliminary Program 4:00 pm 5:30 pm Is Ischemic Preconditioning Ready for Clinical Trials? (Experimental Mechanisms and Models) Moderators: Frank Sharp, BS, MD, Sacramento, CA Miguel A Perez-Pinzon, PhD, Miami, FL EPO and Hypoxia Preconditioning Myriam Bernaudin, PhD, F Caen Cedex, France Thrombin Preconditioning Guohua Xi, MD, Ann Arbor, MI Preconditioning in Clinic? Brian Silver, MD, Detroit, MI Therapeutic Implications of Preconditioning: Induced P450 Epoxygenase Nabil J Alkayed, MD, PhD, FAHA, Portland, OR Neurohospitalists: Bridging Gaps in Patient Care (In-Hospital Treatment) Moderators: William D Freeman, MD, Jacksonville, FL Gary Gronseth, MD, Kansas City, KS What Is a Neurohospitalist and Do We Need One? David Likosky, MD, Kirkland, WA Neurohospitalists and Stroke Outcomes: Are We Getting the Job Done? S Andrew Josephson, MD, San Francisco, CA Neurohospitalists in Academic vs Community Medical Centers: Where Is the Best Fit? Arshad Majid, MD, Lansing, MI Neurohospitalists: Debates in Stroke Call Coverage Kevin M Barrett, MD, Jacksonville, FL Ischemic Stroke Is Treatable: Intra-arterial Recanalization Therapy (Ischemic Stroke Intervention) Moderators: Ajay K Wakhloo, MD, Boston, MA Nobuyuki Sakai, MD, DMSc, Kobe, Japan An Evidence-based Assessment of Intra-arterial Therapy in 2010 Wade Smith, MD, PhD, San Francisco, CA Mechanical Thrombectomy Merci vs Penumbra Italo Linfante, MD, Miami, FL Acute Angioplasty and Stenting and Future Development Elad I Levy, MD, Buffalo, NY s: Community/Risk Factors s: Outcomes, Quality and Health Services Research s: Vascular Malformations 5:30 pm 6:30 pm Professor-Led Poster Tours by Category Session II: Moderated Q&A with Poster Presenters Science and Technology Hall (Exhibits) Thursday, Feb. 25 7:30 am 9:00 am Acute Stroke with a Twist: To Treat or Not To Treat? (Emergency Medicine) Moderators: Peter D Panagos, MD, St Louis, MO Edward C Jauch, MD, MS, FAHA, FACEP, Charleston, SC Shake, Rattle, Let s Roll: Seizures in the Acute Stroke Patient Too Sweet to Treat: Extremes of Glucose in the Setting of TPA Karen Johnston, MD, FAHA, Charlottsville, VA Under Pressure: How Aggressive Is too Aggressive When Lowering BP in Acute Stroke Jamary Oliveira-Filho, MD, PhD, Salvador, Brazil Too Good To Be True: Rapid Improvement in Acute Stroke Will It Last? Eric E Smith, MD, Calgary, AB, Canada Dysphagia After Stroke (Multidisciplinary Clinical Rehabilitation) Moderators: Stephanie K Daniels, PhD, Houston, TX Marlis Gonzalez-Fernandez, MD, PhD, Baltimore, MD Management of Dysphagia After Stroke Stephanie K Daniels, PhD, Houston, TX Neural Basis of Swallowing Disorders After Stroke Ianessa Humbert, PhD, Baltimore, MD Dysphagia After Stroke: The Effect of Respiration on Swallowing Marlis Gonzalez-Fernandez, MD, PhD, Baltimore, MD Bedside Evaluation of Dysphagia: Stroke Specific Tools Giselle Mann, MPH, PhD, Gainesville, FL State-of-the-Art Surgical and Endovascular Treatment for Intracranial Occlusive Disease (Intracranial Atherosclerotic Occlusive Disease) Moderators: Sepideh Amin Hanjani, MD, FACS, Chicago, IL Raul G Nogueira, MD, Boston, MA Endovascular Revascularization of Intracranial Complete Occlusions Felipe Albuquerque, MD, Phoenix, AZ Lessons Learned from WASID and Implications for SAMMPRIS Marc I Chimowitz, MD, FAHA, Charleston, SC Cerebral Hemodynamics for Patients with Carotid Occlusion: An Update from the Carotid Occlusion Surgery Study (COSS) Gregory J Zipfel, MD, Saint Louis, MO Flow Dynamics, Modeling and Stenting in Intracranial Occlusive Disease Ajay K Wakhloo, MD, Worcester, MA s: In-Hospital Treatment s: Ischemic Stroke Intervention s: Neurovascular Unit in Ischemia: Basic Science 9:00 am 9:15 am For the most current program information, please visit strokeconference.org, Program Information page.

9 9:15 am 10:15 am Do We Really Need PFO Closure Trials? (Debate) (Preventive Strategies) Moderator: Richard W Smalling, MD, PhD, FAHA, Houston, TX PFOs Should Be Closed Only if RCTs Demonstrate Safety and Efficacy Mauro Moscucci, MD, MBA, Miami, FL No Need to Wait for Data, PFO Closure Is Here to Stay Aimee Armstrong, MD, Ann Arbor, MI Informed Consent: Have We Gone Too Far or Not Far Enough? (Debate) (Emergency Medicine) Moderators: Phillip Scott, MD, FAHA, Ann Arbor, MI Lee H Schwamm, MD, FAHA, Boston, MA Can We Truly Obtain Informed Consent in Acute Stroke? A Bioethics Perspective Donna T Chen, MD, MPH, Charlottesville, VA Clinical Justice: Balancing the Rights of the Patient Before You with the Need to Perform Clinical Research for the Benefit of All Patients Thomas I Cochrane, MD, Boston, MA Exception from Informed Consent: Ethical, Legal, and Practical Considerations Jeffrey L Saver, MD, FAHA, FAAN, Los Angeles, CA Intravenous vs Intra-arterial Therapy for Acute Ischemic Stroke (Debate) (Acute Management) Moderator: Kyra Becker, MD, Seattle, WA Evidence Doesn t Identify Either Intravenous or Intra-arterial Therapy as Clearly Superior Thomas A Kent, MD, Houston, TX Evidence to Support the Use of Intra-arterial Therapy Peter Schellinger, MD, PhD, Erlangen, Germany What to Do in the Hour Time Window? Werner Hacke, MD, FAHA, Heidelberg, Germany What Should Be the Standard of Care for Asymptomatic Carotid Stenosis? (Debate) (Carotid Revascularization) Moderator: Seemant Chaturvedi, MD, Detroit, MI The Standard of Care for Aymptomatic Carotid Stenosis Should Be Randomisation to Stenting or Surgery Alison Halliday, MS, FRCS, Oxford, United Kingdom The Standard of Care for Asymptomatic Carotid Stenosis is Stenting Pierre B Fayad, MD, FAHA, Omaha, NE The Standard of Care for Asymptomatic Carotid Stenosis is Intensive Medical Therapy J David Spence, MD, London, ON, Canada Controversies in the Management of Cerebral Arteriovenous Malformations: Where We Are and Can ARUBA Help? (Debate) (Vascular Malformations) Moderator: Murat Gunel, MD, New Haven, CT Who to Treat and When M Christopher Wallace, MD, MSc, FRCSC, FACS, Toronto, ON, Canada ARUBA Will Help Answer These Questions Robert D Brown, MD, MPH, Rochester, MN ARUBA Will Not Help Answer These Questions Kevin Cockroft, MD, MSc, FACS, Hershey, PA Q&A The Economics of Stroke (Debate) (Outcomes, Quality and Health Services Research) Moderators: Joseph Broderick, MD, FAHA, Cincinnati, OH Thomas G Brott, MD, Jacksonville, FL The Economics of Aneurysm Coiling and Clipping Brian Hoh, MD, Gainesville, FL The Impact of New DRGs for t-pa, Concentric and Penumbra on Acute Stroke Therapy in the US David Tirschwell, MD, MSc, Seattle, WA Arterial Stenting and Closure Devices: CMS s Role in Randomized Clinical Trials Anthony J Furlan, MD, Cleveland, OH Devices in Stroke: Striking a Balance Between Innovation and Clinical Effectiveness A Proposal Thomas G Brott, MD, Jacksonville, FL 10:15 am 11:00 am Break 11:00 am 12:30 pm Vascular Cognitive Impairment and Alzheimer Disease: Is There a Common Mechanism? (Vascular Cognitive Impairment) Moderators: Patrick Pullicino, MD, PhD, FAHA Canterbury, United Kingdom Randolph Marshall, MD, New York, NY Regional Hypoperfusion and Focal Cognitive Deficits Argye E Hillis, MD, Baltimore, MD Cognitive Impairment from Global Hypoperfusion: Cardiac Disease Ronald M Lazar, PhD, New York, NY Neurovascular Alterations in Alzheimer Disease Berislav V Zlokovic, MD, PhD, Rochester, NY Cognitive Outcomes in Stroke Clinical Trials: Treatment of Cerebral Hypoperfusion Randolph S Marshall, MD, New York, NY Secondary Prevention Adherence: Identifying Barriers and Novel Strategies for Improvement (Preventive Strategies) Moderators: Cheryl Bushnell, MD, FAHA, Winston Salem, NC Bruce Ovbiagele, MD, FAHA, Los Angeles, CA Race-ethnic and Regional Patterns of Stroke Prevention Adherence: The REGARDS Data David Brenner, MD, Birmingham, AL Patient-centric Factors Related to 12-month Adherence to Stroke Prevention Medication: The AVAIL Registry Dai-Wai Olson, PhD, RN, CCRN, Durham, NC

10 ISC Preliminary Program Access to Secondary Stroke Prevention Medications: Novel Strategies to Decrease Barriers from the National Health Interview Survey Deborah Levine, MD, MPH, Ann Arbor, MI Improving Behavioral Lifestyle Change Strategies After Stroke in Veterans: Data From the VA QUERI Teresa Damush, PhD, Indianapolis, IN Subarachnoid Hemorrhage: Current Protocols and Future Prospective (SAH Management) Moderators: Brian Hoh, MD, Gainesville, FL Italo Linfante, MD, Miami, FL SAH Epidemiology and Outcomes Matthew L Flaherty, MD, Cincinnati, OH NICU Management of SAH: Current Protocols and Future Directions Stephan A Mayer, MD, FAHA, New York, NY Microsurgical Clipping: Special Considerations in Treatment of Ruptured Aneursysms B Gregory Thompson, MD, Ann Arbor, MI Coil Embolization of Ruptured Aneurysms: Review of the Evidence Giuseppe Lanzino, MD, FAHA, Rochester, MN s: Experimental Mechanisms and Models s: Intracranial Atherosclerotic Disease s: Multidisciplinary Clinical Rehabilitation 12:30 pm 12:45 pm 12:45 pm 2:00 pm Science and Technology Hall (Exhibits) and Lunch Break Professor-Led Poster Tours by Category Session III: Moderated Q&A with Poster Presenters Fellow and Early Career Luncheon (ticket required; seating is limited) 2:00 pm 3:30 pm Stroke Prevention Among the Young with Heart Disease: Controversies in the Use of Antithrombotic Therapy (Pediatric Stroke) Moderators: Neil Friedman, MD, Cleveland, OH Stephen Ashwal, MD, Loma Linda, CA The Changing Landscape of Morbidity Among Long-term Survivors of Congenital Heart Disease: Factors Affecting Risk for Stroke Across the Life Span J William Gaynor, MD, Philadelphia, PA Role of Thrombophilia and Controversies in Antithrombotic for Stroke Prevention in CHD Ulrike Nowak-Gottl, MD, Munster, Germany Overview of Incidence and Pathophysiology of Ischemic Stroke in Congenital Heart Disease Controversies in the Management of PFO in Secondary Stroke Prevention Steve Messe, MD, Philadelphia, PA Burning Issues in Quality of Life in Stroke Survivors and Caregivers (Nursing) Moderators: Janice L Hinkle, RN, PhD, FAHA, Little More, United Kingdom Tamilyn Bakas, RN, FAHA, Indianapolis, IN Overview of the Burning Issues in Quality of Life Research of Stroke Survivors and Caregivers Rosemarie King, RN, PhD, FAHA, Chicago, IL Depression and Quality of Life Pamela H Mitchell, RN, Seattle, WA Quality of Life and the Marital Dyad After Stroke Teri Green, BS, PhD, Calgary, AB, Canada Quality of Life for Caregivers Joan Grant, RN, Birmingham, AL Stroke: Committing to a World Stroke Agenda (Stroke journal session) Moderators: Vladimir Hachinski, MD, FRCPC, DSc, London, ON, Canada Marc Fisher, MD, Worcester, MA s: SAH Management s: Diagnosis II s: Community/Risk Factors II 3:30 pm 4:00 pm Break/Science and Technology Hall (Exhibits) 4:00 pm 5:30 pm Activity-dependent Plasticity in Stroke Rehabilitation: Lessons from the Developing Brain (Pediatric Stroke) Moderators: Sabrina E Smith, MD, PhD, Philadelphia, PA Jerome Yager, MD, Edmonton, AB, Canada Basic Principles of Activity-dependent in the Developing Corticospinal System: Implications for Therapy J Martin, PhD, New York, NY TMS Studies in Congenital Hemiplegia: Abnormalities in Cortical Excitability as a Therapeutic Opportunity Prospects for TMS in Treatment of Childhood Stroke Adam Kirton, MD, MSc, FRCPC, Calgary, AB, Canada TMS in Stroke Rehabilitation: Lessons from Adult Studies Leonardo G Cohen, MD, Bethesda, MD The Tipping Point: New Approaches to the Decision to Anticoagulate (Hemorrhage Intraparenchymal) Moderators: Mark H Eckman, MD, Cincinnati, OH Steven M Greenberg, MD, PhD, Boston, MA Who ISN T Being Anticoagulated? Daniel Singer, MD, Boston, MA Who SHOULDN T Be Anticoagulated? Robert G Hart, MD, San Antonio, TX Can Genetics Help? Jonathan Rosand, MD, Boston, MA For the most current program information, please visit strokeconference.org, Program Information page.

11 Where Is the Tipping Point in the Decision to Anticoagulate? Mark H Eckman, MD, Cincinnati, OH The Science of Behavior Change for Stroke Prevention and Acute Treatment (Outcomes, Quality and Health Services Research) Moderators: Walter Koroshetz, MD, Bethesda, MD Lewis B Morgenstern, MD, FAHA, Ann Arbor, MI Behavior Change Is Science, Not Advertising Kathleen Conley, PhD, Ypsilanti, MI Strategies for Prevention vs Acute Treatment Bernadette Boden-Albala, MPH, DrPH, New York, NY Targeting High-Risk Groups Devin L Brown, MD, FAHA, Ann Arbor, MI Putting a Team Together for Behavior Change Research Dawn Kleindorfer, MD, FAHA, Cincinnati, OH Brain Lipids Pro and Con: What Are LOX and COX Doing in the Ischemic Brain? (Neurovascular Unit in Ischemia: Basic Science) Moderators: Louise D McCullough, MD, PhD, Farmington, CT Anna M Planas, PhD, Barcelona, Spain Cyclooxygenases and the Risk of Stroke 12/15-Lipoxygenase and Brain Damage Following Stroke Klaus Van Leyen, PhD, Charlestown, MA Prostaglandin Receptors I: EP2 and EP4 Are Good Katrin Andreasson, MD, Stanford, CA Prostaglandin Receptors II: EP1 and EP3 Are Bad Sylvain Dore, PhD, Baltimore, MD Neuroprotective Implications of Lipid Signaling Nicolas G Bazan, MD, PhD, New Orleans, LA Genetic Cerebral Vasculopathies: New Insights in Pathogenesis and New Avenues for Interventions? (Pediatric Stroke) Moderators: Steven Pavlakis, MD, Brooklyn, NY Mark Mackay, MBBS, DipRACOG, FRACP, Melbourne, Australia Overview of Vasculopathies in Childhood Stroke Vijeya Ganesan, MD, London, United Kingdom The Role of Defects in NOTCH Signaling in Alagilleassociated Vasculopathy Binita Kamath, MD, Toronto, ON, Canada The Molecular/Genetic Mechanisms in NF-associated Vasculopathy David A Ingram, MD, Indianaopolis, IN The Role of Defects of Elastin Gene Signaling Disordered Vasculogenesis in Williams Syndrome 5:30 pm 6:30 pm Professor-Led Poster Tours by Category Session IV: Moderated Q&A with Poster Presenters Science and Technology Hall (Exhibits) Friday, Feb. 26 8:00 am 9:30 am Nursing Interventions in Acute Stroke (Nursing) Moderators: Wende N Fedder, RN, BSN, MBA, FAHA, Chicago, IL Nancy D Ashley, RN, MSN, Louisville, KY Communicating Across the Chasm: Coordinating Acute Stroke in Telemedicine Systems Connie F Parliament, MSN, RN, Pontiac, MI What Can We Learn from Nurses Experience in Expediting MI Reperfusion? Tom Quinn, RN, MN, FESC, Guildford, United Kingdom Care of the Cooled Brain: Nursing Care for Hypothermia in Acute Stroke Anne Alexandrov, PhD, RN, CCRN, FAAN, Birmingham, AL Assessing for Risk: Depression in Acute Stroke Margaret Kelly-Hayes, EdD, RN, FAAN, Boston, MA What Do They Know? Evidence-based Guidelines for Educating Stroke Patients After Discharge Sharon K Ostwald, PhD, RN, FGSA, Houston, TX Epigenetics and Stroke Protection and Recovery: From Molecules to Man (Experimental Mechanisms and Models) Moderators: Sean I Savitz, MD, FAHA, Houston, TX Rajiv R Ratan, MD, PhD, White Plains, NY Overview of Epigenetics in Stroke Rajiv R Ratan, MD, PhD, White Plains, NY Sirtuins, Regulators of Aging and Ischemic Precondition Miguel A Perez-Pinzon, PhD, Miami, FL Class I and II HDAC Inhibitors as Neuroprotective and Neurorestorative Agents Brett Langley, PhD, White Plains, NY Epigenetic and Stem Cell Differentiation for Stroke Repair Defending the Stroke Guidelines (Forum) Moderators: Scott E Kasner, MD, MS, FAHA, Philadelphia, PA Colin Derdeyn, MD, FAHA, St. Louis, MO Guideline and Scientific Statement Development Scott E Kasner, MD, MS, FAHA, Philadelphia, PA Subarachnoid Hemorrhage Joshua B Bederson, MD, New York, NY Expansion of the Time Window for Treatment of Acute Ischemic Stroke with Intravenous Tissue Plasminogen Activator Gregory J del Zoppo, MD, MS, FAHA, Seattle, WA Definition and Evaluation of Transient Ischemic Attack J Donald Easton, MD, FAHA, Providence, RI Prevention of Stroke in Patients with Stroke and TIA Karen L Furie, MD, MPH, FAHA, Boston, MA

12 ISC Preliminary Program Topics Under Development (Race-Ethnic Disparities in Stroke Care, Cerebral Vein Thrombosis, Vascular Dementia, Primary Prevention, Intracerebral Hemorrhage) Colin Derdeyn, MD, FAHA, St. Louis, MO Dissemination and Implementation of Guidelines and Statements: Professional Education Dawn Kleindorfer, MD, FAHA, Cincinnati, OH s: Aneurysm s: Chairs Choice s: Acute Management II 9:30 am 9:45 am 9:45 am 11:15 am Crossing the Barrier: Drug Delivery to the Ischemic Brain (Neurovascular Unit in Ischemia: Basic Science) Moderators: Midori A Yenari, MD, FAHA, San Francisco, CA Thomas P Davis, MD, Tucson, AZ Physiology and Pathology of the BBB Thomas P Davis, MD, Tucson, AZ Clinical Challenges of Drug Delivery to the Brain Edward Neuwelt, MD, Portland, OR Imaging the BBB in Stroke Gary A Rosenberg, MD, Albuquerque, NM Novel Nano-agents for Drug Delivery and in Vivo Imaging Comprehensive Stroke Centers: The Future of Stroke Care (Outcomes, Quality and Health Services Research) Moderators: Mark J Alberts, MD, FAHA, Chicago, IL Adnan I Qureshi, MD, FAHA, Minneapolis, MN Comprehensive Stroke Centers: An Overview Mark J Alberts, MD, FAHA, Chicago, IL Interaction Between Primary and Comprehensive Stroke Centers and the Community: Theoretical and Practical Models Pooja Khatri, MD, Cincinnati, OH Endovascular Component in the Comprehensive Stroke Center: Policies, Standards and Oversight Adnan I Qureshi, MD, FAHA, Minneapolis, MN Neurosurgical Component in the Comprehensive Stroke Center: Policies, Standards and Oversight Kevin Cockroft, MD, MSc, FACS, Hershey, PA Stroke and the Law: Legal Issues in Cerebrovascular Disease Moderators: Mark Fisher, MD, Irvine, CA John Cole, MD, MSEE, Baltimore, MD Principles of Legal Medicine in Stroke Mark Fisher, MD, Irvine, CA Informed Consent, tpa Use, and Legal Aspects of Acute Stroke Treatment Justin Zivin, MD, PhD, FAHA, La Jolla, CA The Expert Witness in Stroke Cases Stark, EMTALA, and Stroke Patient Transfers s: Carotid Revascularization s: Outcomes, Quality and Health Services Research II s: Experimental Mechanisms and Models II 11:15 am 11:30 am 11:30 am 1:00 pm Plenary Session II Poster Viewing Hours To provide additional hours for poster viewing, the Poster Hall will be open during these hours: Wednesday, Feb. 24 9:00 am 6:30 pm Thursday, Feb. 25 9:00 am 6:30 pm NEW THIS YEAR: Professor-Moderated Poster Tours! Leaders in the stroke field will take groups of attendees around speaker-attended posters for a Q&A with the poster presenters. Poster tours will be arranged by category. Professor-moderated poster tours are scheduled as follows: Wednesday, Feb :45 pm 1:45 pm and 5:30 pm 6:30 pm Thursday, Feb :45 pm 1:45 pm and 5:30 pm 6:30 pm Please go to strokeconference.org, Program Information page. E-posters E-posters will be viewable in the Poster Hall from 9:00 am 6:30 pm. Registered attendees can also view the E-posters at strokeconference.org. For the most current program information, please visit strokeconference.org, Program Information page.

13 Registration and Housing Registration and Housing for ISC, the Nursing Symposium and the Stroke journal pre-con will open as follows: FAHA Members* Oct. 12 AHA/ASA Members* Oct. 19 Nonmembers Oct. 26 Join AHA/ASA Professional Membership and Save on Registration! As a Member you can potentially receive the following savings on registration:** Stroke Professionals, save up to $300 on ISC registration. Nurses, save up to $100 on Stroke Nursing Symposium registration and $320 on ISC registration. * Must become a member on or before Sept. 30, 2009 to qualify for priority registration and housi ng. ** Must be a member on or before Jan. 29, 2010 to receive registratio n discounts. Registration savings dependent on membership tier. Become an AHA/ASA Professional Member Today! Visit my.americanheart.org Promo Code D9J163ZZ HOW TO REGISTER Web: Book your hotel and register online at strokeconference.org. Promo Code DM501 Phone, Fax or Mail: For registration instructions and downloadable forms, go to strokeconference.org and click on Registration and Housing. A one-time $10 service charge will be assessed if you choose one of these options. On-Site Registration: On-site registrants must have a photo ID. For security reasons, you cannot register another attendee or pick up another attendee s registration materials. Please visit strokeconference.org, Registration and Housing page, for the following information: International Information Registration Reminders/Deadlines Membership Information Registration Refund/Cancellation Policy Hotel Information Including Cancellation Policy, Conference Hotels and the Hotel Map Onsite Registration Information and Registration Hours Additional General Event Policies Registration Fees: International Stroke Conference Advance On Site Registration Categories Until Jan. 29 After Jan. 29 Premium Professional Plus Member $490 $590 Premium Professional Member $490 $590 General Professional Member $790 $890 Emeritus Member $75 $175 Early Career Member $490 $590 Nurse Premium Professional Plus Member $305 $405 Nurse Premium Professional Member $305 $405 Nurse General Professional Member $325 $425 Student/Trainee Member $290 $390 EMT/Paramedic Premium Professional Plus Member $305 $405 EMT/Paramedic Premium Professional Member $305 $405 EMT/Paramedic General Professional Member $325 $425 Technician Member $290 $390 One Day Only (Wednesday/Thursday) Member $275 $375 One Day Only (Friday) Member $200 $300 Nonmember $790 $890 Early Career Nonmember $7 90 $890 Nurse Nonmember $625 $725 Student/Trainee Nonmember $390 $490 EMT/Paramedic Nonmember $625 $725 Technician Nonmember $390 $490 One Day Only (Wednesday/Thursday) Nonmember $375 $475 One Day Only (Friday) Nonmember $300 $400 Spouse/Adult Family Member (Exhibits Only) $100 $200 Registration Fees: State-of-the-Art Stroke Nursing Symposium Member $100 $200 Nonmember $200 $300 Registration Fees: Stroke journal pre-conference symposium: As Stroke Turns 40 Committing to a Stroke Global Action Plan Member and Nonmember $250 $250 Register Online Today! strokeconference.org Promo Code DM501

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