Summer School Program. Date: 4th - 8th July, 2016 Venue: Schlosswirtschafthotel, Herrenchiemsee, Prien am Chiemsee, Germany. Monday, July 4th, 2016

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1 Summer School Program NEURAL CIRCUITS OF PAIN AND THEIR REORGANISATION IN CHRONIC PAIN Date: 4th - 8th July, 2016 Venue: Schlosswirtschafthotel, Herrenchiemsee, Prien am Chiemsee, Germany Monday, July 4th, :45-09:00 Registration, welcome and orientation 09:00-10:30 REFRESHER COURSE: BASIC CIRCUIT MODULE - I 09:00-09:45 Martin Schmelz, Heidelberg University, Germany: Distinct classes of nociceptors - functional and structural differentiation. 9:45-10:30 Stefan Lechner, Heidelberg University, Germany: Spinal circuits of 11:00-12:30 REFRESHER COURSE: NEUROBIOLOGY MODULE 11:00-11:45 Rohini Kuner, Heidelberg University, Germany: Neurobiology of 11:45-12:30 Simon Beggs, University of Toronto, Canada: Glia, signaling mediators. 12:30-14:00 Lunch and registration for workshops 14:00-15:30 REFRESHER COURSE: CLINICAL PAIN SYNDROMES MODULE 14:00-14:45 Rolf-Detlef Treede, Heidelberg University, Germany: Neuropathic 14:45-15:30 Hans-Georg Schaible, University of Jena, Germany: Phenotype and neuronal mechanisms of inflammatory 15:30-16:30 Coffee break and registration for workshops 16:30-18:00 REFRESHER COURSE: BASIC CIRCUIT MODULE - II 16:30-17:15 Herta Flor, Central Institute of Mental Health, Mannheim, Germany: Representation of pain in brain. 17:15-18:00 Frauke Nees, Central Institute of Mental Health, Mannheim, Germany: Expectancy, salience network. 18:00-18:45 REFRESHER COURSE: PAIN RHYTHMS - I 18:00-18:45 Alexander Groh, Technical University, Munich, Germany: Pain processing in the thermocortical system.

2 Tuesday, July 5th, :00-13:00 SESSION 1: SENSORY CIRCUITS AND PLASTICITY 09:00-09:45 Paul Heppenstall, EMBL, Italy: Mapping peripheral neural circuits. 09:45 10:30 Martin Schmelz, Heidelberg University, Germany: Excitability changes of nociceptors in patients with hereditary erythromelalgia. 11:00-11:45 Rolf-Detlef Treede, Heidelberg University, Germany: Central sensitization. 11:45-12:30 Hilmar Bading, Heidelberg University, Germany: Excitationtranscription coupling in the spinal cord: role in the chronification of 12:30-13:00 2 Datablitz trainee talks: Nikita Khovanov & Louise Gorham 14:00-15:00 Parallel methods workshops 15:00-17:00 Free time // Coffee available from 16:00-17:00 17:00-18:45 SESSION 2: PAIN AND THE BRAIN 17:00-17:45 Rainer Spanagel, Central Institute of Mental Health, Mannheim, Germany: Neuroplasticity in corticolimbic dopaminergic and glutamatergic pathways. 17:45-18:30 Herta Flor, Central Institute of Mental Health, Mannheim, Germany: Neural mechanisms involved in phantom limb 18:30-18:45 Datablitz trainee talk: Christopher Milde

3 Wednesday, July 6th, :00-13:00 SESSION 3: NEUROBIOLOGY 09:00-09:45 Jan Siemens, Heidelberg University, Germany: TRP channels in pain and temperature sensation. 09:45-10:30 Carla Nau, University of Lübeck, Germany: Voltage-gated sodium channels and pain - a human disease. 11:00-11:45 Hans-Georg Schaible, University of Jena, Germany: The role of cytokines in 11:45-12:30 Jeffrey Mogil, McGill University, Canada: Sex differences in pain from both sides of the syringe. 12:30-13:00 2 Datablitz trainee talks;: Thomas Klein & Kieran Boyle 14:00-15:00 Parallel methods workshops 15:00-17:00 Free time // Coffee available from 16:00-17:00 17:00-18:45 SESSION 4: REORGANIZATION IN THE BRAIN 17:00-17:45 Thomas Kuner, Heidelberg University, Germany: In vivo imaging of cortical structural plasticity in neuropathic 17:45-18:00 Datablitz trainee talk: Livia Asan 18:00-18:45 Trainee Debates 1 & 2, moderated by faculty 19:30-21:00 Dinner (for faculty at Yacht club in Gollenshausen; for trainees at Hotel Luitpold am See, House 2)

4 Thursday, July 7th, :45-13:00 SESSION 5: SPINAL CORD 08:45-09:30 Mike Salter, University of Toronto, Canada: From receptors to pain: the molecular dynamics of 09:30-10:15 Yves De Koninck, Laval University, Quebec, Canada: Decoding pain circuit processing with optical approaches. 10:15-10:45 Coffee break 10:45-11:30 Norbert Weidner, Heidelberg University, Germany: Central neuropathic pain in spinal cord injury. 11:30-12:00 2 Datablitz trainee talks: Oscar Retana & Adriano Franciosi 12:00-12:30 Lunch 12:45 Ferry and optional trip to Berchtesgaden/Obersalzberg

5 Friday, July 8th, :00-13:00 SESSION 6: REWARD LEARNING AND COGNITIVE FACTORS 09:00-09:45 Sigrid Eisenbruch, University of Essen, Germany: Behavioural and neural mechanisms of human visceral 09:45-10:30 Karin Davis, University of Toronto, Canada: Individual differences in the dynamic pain connectome underlie intrinsic attention to pain, mindwandering and prioritizing cognitive demands while in 11:00-11:45 Petra Schweinhardt, McGill University, Canada: Mesolimbic dopamine signalling in acute and chronic pain: Implications for motivation analgesia and addiction? 11:45-12:30 Sabine Herpertz, Heidelberg University, Germany: Oxytocin and social behaviour. 12:30-13:00 2 Datablitz trainee talks: Alexandra Tinnermann & Joshua Cheng 14:00-15:30 SESSION 7: PAIN RHYTMS - II 14:00-14:45 Markus Ploner, Technical University Munich, Germany: Neural gamma oscillations and the perception of 14:45-15:30 Ulf Baumgärtner, Heidelberg University, Germany: Evoked phasic versus ongoing pain and their correlates in the time-frequency domain. 15:30-16:30 Coffee available 16:30-17:30 Trainee Debates 3 & 4, moderated by faculty 17:30-18:30 Exercise in planning your own research project, divided into 4-5 groups, moderated by faculty :40 Break and rearrangement of groups 18:40-18:45 Closing remarks

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