FROM OLD RISK FACTORS TO EMERGING DIAGNOSTIC AND THERAPEUTIC OPPORTUNITES

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1 NEW STRATEGIES FOR REDUCING CARDIOVASCULAR RISK: FROM OLD RISK FACTORS TO EMERGING DIAGNOSTIC AND THERAPEUTIC OPPORTUNITES FEDERICO II UNIVERSITY MEDICAL SCHOOL Naples (Italy) 2017 February 9 th - 11 th Organized by: Department of Advanced Biomedical Sciences Federico II University of Naples (Italy) Course Director Pasquale Perrone Filardi Department of Advanced Biomedical Sciences Federico II University of Naples (Italy) Congress Chairs: Pasquale Perrone Filardi Bruno Trimarco

2 COURSE DIRECTOR: Prof. Pasquale Perrone Filardi Professor of Cardiovascular Diseases Department of Advanced Biomedical Sciences Federico II University, Naples, Italy PROMOTED BY: Fondazione Internazionale Menarini Centro Direzionale Milanofiori Rozzano (Milan, Italy) Edificio L - Strada 6 Phone: Fax milan@fondazione-menarini.it - website: ORGANIZING SECRETARIAT AND PROVIDER: Contatto S.r.l. ECM ECM ID 126 Via Vincenzo Lancia, 27 - I Turin (Italy) Phone: / Fax: info@contatto.tv Web site:

3 GENERAL INFORMATION Meeting venue Federico II University Medical School, Via Partenope, 36 - Naples Registration hours The Registration Desk will be open during the following hours: Thursday 9th February 2017: to Friday 10th February 2017: to Saturday 11th February 2017: to Official language English. Simultaneous translation will not be provided. Registrations Registration is free of charge. Please confirm your participation to the Organizing Secretariat (Fondazione Internazionale Menarini Phone: Fax: milan@fondazione-menarini.it) within June 1st, Italian CME Accreditation The Meeting has obtained 14 CME Credits for Italian Physicians. The CME credits will be recognized only after full attendance of all sessions and a minimum score of 75% of correct answers in the learning questionnaires. Completion of the Registration Form, the Learning & Assessment questionnaires are compulsory. European CME Accreditation The event has been accredited by the European Board for Accreditation in Cardiology (EBAC) for tbc European CME Credits covering the whole programme. Technical facilities A Slide Centre with PCs (Windows and Macintosh operating systems) will be available for Speakers to preview and finalize their presentations. Speakers are kindly requested to submit their presentations on USB flash drive, CD or DVD to the Slide Centre technicians at least one hour before their talks. Slide Centre opening hours Thursday 9th February 2017: to Friday 10th February 2017: to Saturday 11th February 2017: to Lunches and coffee breaks Lunches and coffee breaks will be provided within the conference premises. Attendance certificate The attendance certificate will be issued at the accreditation/registration desk following full attendance at the Conference.

4 PROGRAMME Day One Thursday 9 th February :00 Welcome address Prof. Luigi Califano Dean of Medicine and Surgery School University negli Studi Federico II, Naples 15:30 Presentation of Educational Needs 16:00 Lecture: New insights in the pathophysiology of hypertension Bruno Trimarco (Federico II University, Naples, Italy) 17:00 Discussion and Question Time on New insights in the pathophysiology of hypertension 17:30 Lecture: Heart Failure and Diabetes epidemiology, pathophysiology and management options Stefan Anker (University Medical Center Göttingen, Germany) 18:30 Discussion and Question Time on Heart Failure and Diabetes epidemiology, pathophysiology and management options 19:00 Closing remarks of the day Chair: Pasquale Perrone Filardi (Federico II University, Naples, Italy)

5 PROGRAMME Day Two Friday 10 th February 2017 SESSION I: IDENTIFYING HIGH RISK ASYMPTOMATIC PATIENTS: EMERGING RISK FACTORS AND STRATEGIES Chairpersons: Francesco Fedele (La Sapienza University, Rome); Marco Metra (University of Brescia, Italy) 09:10 Refining CV risk in asymptomatic subjects: the role of biomarkers Massimo Volpe (Sapienza University, Rome, Italy) Subclinical organ damage: the role of imaging Paolo Colonna (Polyclinic of Bari) Epicardial adipose tissue: an emerging opportunity for risk stratification Dario Leosco (Federico II University, Naples, Italy) 10:40 Epigenetic and CV risk profiling Giuseppe Mercuro (University of Cagliari, Italy) 11:10 Discussion 11:30 Coffee Break SESSION II: FACING CARDIOVASCULAR RISK: FOCUS ON GLYCEMIA Chair: Dario Giugliano (Secon University of Naples, Italy) Vincenzo Mollace (Magna Graecia University, Catanzaro, Italy) 11:50 Metabolic syndrome, insulin resistance and CV risk Stefania Paolillo (Federico II University, Naples, Italy) How low glycated haemoglobin should be in the high risk patient? Giorgio Sesti (MagnaGraecia University, Catanzaro)

6 PROGRAMME 12:50 Anti-diabetic drugs and CV events: what the cardiologist did not expect Francesco Cosentino (Karolinska Medical school, Stockholm, Sweden) Mediterranean diet, olive oil and CV risk Katherine Esposito (Second University of Naples, Italy) Discussion Light lunch III SESSION: FACING CARDIOVASCULAR RISK: FOCUS ON LIPIDS Chairs: Paolo Golino (Second University of Naples, Italy); Giovanni Esposito (Federico II university, Naples, Italy) 14:40 Targeting LDL in high risk patients: how low we should get? How? Paolo Calabrò (Second University of Naples, Italy) Beyond LDL: are there additional lipid parameters we should focus on? Alberico Catapano (University of Milan, Italy) New pharmacologic anti-lipidic strategies on the horizon Maurizio Averna (University of Palermo, Italy) CV risk prevention in patients at intermediate risk: the message from the HOPE 3 trial Pasquale Perrone Filardi (Federico II University, Naples, Italy) Discussion Refreshments

7 PROGRAMME IV SESSION: FACING CARDIOVASCULAR RISK: FOCUS ON BLOOD PRESSURE Chairs: Gianfranco Parati (Istituto Auxologico, University of Milan, Italy), Marino Scherillo (Rummo Hospital, Benevento, Italy) 16:30 Reconcilying SPRINT and HOPE3 trials: is intensively reducing blood pressure useful? Giuseppe Mancia (University Milano-Bicocca, Italy) 17:00 Hyperuricemia, blood pressure and metabolic syndrome: linking uric acid to CV events Claudio Borghi (University of Bologna, Italy) 17:20 Traveling through the anti-hypertensive drug combinations: how the choice should be guided Claudio Ferri (University of L Aquila, Italy) 17:40 Discussion 18:00 Closing Remarks of the Day

8 PROGRAMME Day Three Saturday 11 th February 2017 SESSION V: FACING CARDIOVASCULAR RISK: FOCUS ON PLATELETS Chairs: Ciro Indolfi (Magna Greacia University, Catanzaro, Italy), Scipione Carerj (University Messina, Italy) Introduction to Day 3 s Topics and Chairman Pasquale Perrone Filardi (Federico II University, Naples, Italy) Prolonging DAPT in the chronic patients: in whom? For how long? Federico Piscione (Salerno University, Italy) 10:00 The need for DAPT after last generation DES Davide Capodanno (University of Catania, Italy) Questions on 1 st to presentations Coffee break The role of thrombin receptor antagonists Giuseppe Ambrosio (University of Perugia, Italy) Aspirin in primary prevention: what more we need to know Carlo Patrono (Rome, Italy) Panel Discussion: Facing Cardiovascular Risk - Focus on Platelets Closing Remarks and adjourn Test CME

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