International Workshop TRANSLATIONAL RESEARCH ON MALIGNANT GLIOMAS: FROM DISCOVERY TO CLINIC

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1 TRANSLATIONAL RESEARCH ON MALIGNANT GLIOMAS: Università degli Studi di Napoli Federico II Consiglio Nazionale delle Ricerche Gruppo Neuro-Oncologico Campano th th Naples, February 18-19, 2010 Villa Doria D'Angri Via Petrarca 80 Under the auspices of: Associazione Italiana di Radioterapia Oncologica Lega Italiana Tumori Sezione di Napoli

2 Scientific Committee Sossio Cirillo (Naples) Francesco Maiuri (Naples) Paolo Muto (Naples) Gianfranco Peluso (Naples) Guido Pettinato (Naples) Riccardo Soffietti (Turin) Scientific Secretariat dott. Orsola Petillo Consiglio Nazionale delle Ricerche Tel.: Organizers Francesco Maiuri (Naples) Gianfranco Peluso (Naples) Organizing Committee Francesco Briganti (Naples) Maria Laura Del Basso De Caro (Naples) Mario Muto (Naples) Roberto Pacelli (Naples) Carmela Peca (Naples) Mosè Rossi (Naples) Organizing Secretariat Collage Congressi - Branch Office Napoli Centro Direzionale - Isola G1 - Scala D Tel Fax segreteria.napoli@collagecongressi.it Web:

3 Dear colleagues and friends, it is our great pleasure to organise in Naples an International Workshop on Translational research on malignant gliomas; from discovery to clinic. This event occurs two years after the international meeting on New diagnostic and therapeutic approaches and future perspectives in neuro-oncology, which has resulted in good scientific interest and participation, thus confirming the activity of neuro-oncologic group. The workshop discusses the more recent acquisitions of the biomolecular research and focuses their applications to the diagnosis and surgical, radiotherapic and chemotherapic management of malignant gliomas. Infact, the progress of molecular biology on the angiogenesis, invasion and cell metabolism of malignant gliomas have significantly improved both the magnetic resonance and nuclear medicine diagnosis and the management, particularly thank to the introduction of new biological therapies. Other discussed interesting topics include the role of the stem cells and the environemental and genetic impact of malignant gliomas. The speakers are among the most experts in each field. We hope that the scientific and clinic interest of the workshop and the presence of many expert speakers will favour a wide participation of specialists devoted to the neuro-oncology and fruitful exchanges of information and opinions. See you in Naples Francesco Maiuri Gianfranco Peluso

4 FACULTY Brunetti A. (Naples) Cao Y. (Stockholm, Swe) Carapella C.M. (Rome) Ciceri E. (Milan) Cirillo S. (Naples) Claus E. (New Haven, USA) De Berardinis R. (Dallas, USA) de Divitiis E. (Naples) Del Basso De Caro M.L. (Naples) Delfini R. (Rome) De Maria R. (Rome) De Paula U. (Rome) DiMeco F. (Milan) Donato V. (Rome) Fabi A. (Rome) Falini A. (Milan) Ferro M. (Campobasso) Giangaspero F. (Rome) Gottlieb E. (Glasgow, UK) Grosu A.L. (Freiburg, Ger) Hegi M. (Lousanne, Swiz) Iacoangeli M. (Ancona) Jacobs A.H. (Cologne, Ger) Krengli M. (Novara) Levi A. (Rome) Lodi R. (Bologna) Maiuri F. (Naples) Melone M.A.B. (Naples) Muto M. (Naples) Muto P. (Naples) Neri G. (Rome) Pace A. (Rome) Peluso G. (Naples) Pettinato G. (Naples) Plate K.H. (Munchen, Ger) Pollo B. (Milan) Rudà R. (Turin) Salmaggi A. (Milan) Salvati M. (Rome) Salvatore M. (Naples) Sanson M. (Paris, Fr) Scerrati M. (Ancona) Schiffer D. (Vercelli - Monza) Silvani A. (Milan) Soffietti R. (Turin) Tomasello F. (Messina)

5 Thursday, February Welcome address and workshop opening Session I: Angiogenesis Chairpersons: R. Delfini (Rome) - P. Muto (Naples) - G.Pettinato (Naples) Tumor pathology and angiogenesis K.H. Plate (Munchen, Ger) Modulation of angiogenesis Y. Cao (Stockholm, Swe) The advanced MR imaging for angiogenesis E. Ciceri (Milan) Radiotherapy and angiogenesis M. Krengli (Novara) Antiangiogenic drugs R. Soffietti (Turin) Discussant M. Scerrati (Ancona) Clinical cases: V. Donato (Rome) - R. Rudà (Turin) Discussion Lunch

6 Session II: Metabolism Chairpersons: A. Brunetti (Naples) - U. De Paula (Roma) Molecular basis for the reprogramming of cancer cell metabolism R. De Berardinis (Dallas, USA) Assessing metabolism of malignant gliomas by MR spectroscopy R. Lodi (Bologna) Advanced PET studies for planning the management of malignant gliomas A.H. Jacobs (Cologne, Ger) Radiotherapy and metabolism A. L. Grosu (Freiburg, Ger) Metabolism as target therapy E. Gottlieb (Glasgow, UK) Discussant R. Soffietti (Turin) Clinical cases: M. Ferro (Campobasso) - A. Salmaggi (Milan) M. Salvati (Rome) Discussion

7 Friday, February 19 Session III: Migration and invasion Chairpersons: M. Salvatore (Naples) D. Schiffer (Vercelli - Monza) Biological basis of local invasion in malignat gliomas F. Giangaspero (Rome) Assessing invasion of malignant gliomas with magnetic resonance A. Falini (Milan) Invasion and migration as target therapy M. Sanson (Paris, Fr) Local gene therapy A. Levi (Rome) Discussant E. Gottlieb (Glasgow, UK) Clinical cases: A. Fabi (Rome) - M. Muto (Naples) - B. Pollo (Milan) Discussion Coffee-break

8 Session IV: Cancer stem cells Chairpersons:ML Del Basso De Caro (Naples) - G. Peluso (Naples) Cancer stem cells: an overview R. De Maria (Rome) Locoregional stem cell therapy in malignant glioma: state of art F. Di Meco (Milan) Discussant A. Silvani (Milan) Discussion Lunch

9 Session V: Epidemiology and clinic Chairpersons: E. de Divitiis (Milan) F. Tomasello (Messina) Malignant gliomas: environemental and non inherited endogenous factors E. Claus (New Haven, USA) The impact of genetic and counseling G. Neri (Rome) Translational research in malignant gliomas: its role in the clinical decision and prediction of the therapeutic response M. Hegi (Lousanne, Swiz) The impact of the translational research on the surgical conduct C.M. Carapella (Rome) Discussant F. Maiuri (Naples) Clinical cases: M. Iacoangeli (Ancona )- M.A.B. Melone (Naples) A. Pace (Rome) Discussion Closing remarks F. Maiuri (Naples) G. Peluso (Naples)

10 GENERAL INFORMATION CONGRESS VENUE Villa Doria D'Angri Via Petrarca,80 Napoli REGISTRATION Before 31/01/ ,00 After 01/02/ ,00 Students: free of charge MODALITA' DI PAGAMENTO -Payment by Banker Account ** [**Credito Emiliano - Ag.6 Palermo Abi Cab c/c 010/ Iban IT89 R ] -Payment by cash/cheque -Payment sponsored by pharmaceutical company, hospital, electro-medical company (please disclose the name of the company in question at the secretariat desk) SCIENTIFIC INFORMATION Official languages: The official languages of the congress are Italian and English. A simultaneous translation service will be available.

11 CONTINUING MEDICAL EDUCATION (ECM) Accreditation has been requested for the following disciplines: Neurosurgery, Neuroradiology, Oncology, Pathology, Radiotherapy, Clinical Biochemistry. ATTENDANCE CERTIFICATE At the end of the meeting the attendance certificate will be given to all registred participants AUDIOVISUAL EQUIPMENT PC projection (Only POWER POINT file on CD or on a memory stick, USB port or DVD) will be provided in the meeting rooms. Speakers are kindly requested to contact the slide center to upload their presentation and to test all the audiovisual material at least one hour before the lecture. THE USE OF PERSONAL LAPTOPS WLL NOT BE ALLOWED.

12 Supported by Platinum Sponsor fondazione muto onlus Civitas Hippocratica Salerno Web Site:

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