11th International Life Science Meeting IMC University of Applied Sciences Krems

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1 11th International Life Science Meeting IMC University of Applied Sciences Krems March 25 th - 26 th, 2014 in partnership with BioNanoMed 5th International Conference March 26-28, 2014 Location: IMC University of Applied Sciences, International Meeting Centre, Krems Since the beginning of the study program Medical and Pharmaceutical Biotechnology in 2002, International Life Science Meetings have been held every year at the IMC University of Applied Sciences Krems. More than 120 guest lecturers from 25 countries and around 200 scientists, clinicians and representatives from Austrian universities, academic institutions and biotech industry have been in Krems in order to discuss with our students, biotech team and our R&D partners. The International Nano-Biotechnology Congress about Scientific and Clinical Applications of Magnetic Carriers at our University in 2006 was our largest conference. It brought together 380 foreign scientists, engineers and clinicians from 43 countries with our 220 biotechnology students. This year s 11 th International Life Science Meeting will focus on the mean topics of the degree programme Medical and Pharmaceutical Biotechnology as well as on our current research topics. Until now governmental projects, EC-grants and collaborations with 18 biotech companies have been completed. The research activities resulted in total funding of around 7,5 Mio. and more than 30 students did finish their bachelor- or master thesis in house. Till present our biotechnology department has more than 500 graduates. 60% of them working in biomedical research fields and 40% in the industrial area. More than 100 graduates are in PhD programs or finished their PhD-thesis in international research- or industrial institutions as Harvard, Cambridge, London, Stockholm, Groningen or in German and Austrian Universities. We can proudly announce that the Wednesday Afternoon Session will be hosted by graduates from our study program. They will share their world-wide experiences from industrial R&D projects as well as those related to PhD-studies in Austria and other countries. The meeting is also our great opportunity to thank our partners and lecturers for their support throughout the last years.

2 March 25, 2014 Room: Main Lecture Hall, FH Krems 10:00 Opening Ceremony H. Hundsberger, Prof.(FH) Dr. Head of Deptartment of Biotechnology, IMC FH Krems Session: Secondary Metabolites of & Protein Based Technologies Chair: Tamara Zmölnig and Barbara Greil, Biotech Students 10:05 Extremophilic Bacteria From Omani Deserts: Novel Processes and Potential to Biotechnology R. M. M. Abed Prof. Dr. Department of Biology, Sultan Qaboos University of Oman 10:25 Cyanobacteria: Promising Source of Bioactive Metabolites J. Kopecky, Dr. Institute of Microbiology, Academy of Sciences of the Czech Republic, Trebon * Research Partner 10:45 Natural Products and their Derivatives as Biological Active Compounds U. Rinner, Dr. Institute of Organic Chemistry, University of Vienna *Lecturer 11:05 Engineering of Lipid Accumulation in Yeasts M. Certik, Prof. Dr.; P. Gajdos Dept. Biochemical Technology, Slovak Univ. of Technology, Bratislava * Research Partner 11:25 Charybdotoxin Unbinding from the mkv1.3 Potassium Channel: A Combined Computational and Experimental Study R. Ettrich, Prof. Dr. Director Institute of Nanobiology and Structural Biology of GCRC Academy of Sciences of the Czech Republic, Nove Hrady *Lecturer, Research Partner 11:45 Wine & Beer & Fructose the (Fatty) Liver Takes It All Missbichler Dr. C.E.O. Sciotec GmbH * Research Partner 12:05 Lunch Break Session: Towards Novel Anti Cancer Approaches Chair: Johanna Wallner and Klemens Weitenthaler, Biotech Students

3 13:30 Identification and Development of Novel Drugs for the Treatment of Cancer and Inflammatory Diseases A. Eger, Prof.(FH) PD Dr. Head of R&D, Dept. Biotechnology, IMC FH Krems 13:50 Current Advances in Applied Molecular Oncology: Research Topics of the RECAMO Institution B. Vojtesek, Dr., D. Valik, Dr. RECAMO Directors, Masaryk Memorial Cancer Inst., Brno Mechanisms to Combat Cancer Progression W. Mikulits, Prof. Dr. Medical University Vienna, Institute of Cancer Research * Lecturer, PTS Coach, PhD Supervisor, R&D Partner 14:30 Development of Protein Kinase Inhibitors with Purine Core M. Strnad, Prof. Dr., V. Krystof, Dr. Lab. Growth Regulators, Inst. Exp. Botany, Olomouc 14:50 Neural Crest-Derived Cells: From Melanoma Cells to Schwann Cells M. Mikula, Prof. Dr. Medical University Vienna * Lecturer, PTS Coach, PhD Supervisor, R&D Partner 15:10 Cytotoxicity and COX-2 Inhibition Activities of Novel Benzaxozoles R. J. Abdel-Jalil, Prof. Dr. Department of Chemistry, Sultan Qaboos University of Oman * R&D Partner 15:30 Personalized Medicine Perspective from a Practicing Pathologist S.K. Kraeft, Dr. Dana Farber Cancer Inst., Harvard Medical School, Boston ( ) Inst. Pathology Wyoming ( ) and Inst. Pathology, Univ. Rostock 15:50 BET inhibitors, new Compounds for the Treatment of Cancer G. Damante, Dipartimento di Scienze Mediche e Biologiche, Università degli Studi di Udine * Joint Master program 16:10 BREAK 16:30-18:00 Board meeting: Working Title ETZ Interreg Austria-Czech Republic: Innovative Technologies in Drug Discovery for Cancer and Inflammatory Diseases Session: International Partners from Science and Industry Chair: Judith Bezgovsek and Petko Petkov, Biotech Students 17:00 Induction of unwanted immune responses a major challenge in the development of new biologics B. Reipert, Priv. Doz. Dr. Director Immunology, Research & Innovation, Baxter Bioscience, Vienna *Lecturer, Supervisor of Master- and PhD thesis, Employer of IMC graduates

4 17:20 Folding and Fibrillogenis of Amyloidogenic Proteins A. Corazza, Prof. Dr. Dipartimento di Scienze Mediche e Biologiche, Università degli Studi, Udine * Double degree Master program 18:00 Influenza- and Coronaviruses of Animal Origin A Threat for Mankind or a Chance for Vaccines? O. Kistner, Dr. Senior Director, Clinical Virology & Scientific Affairs, Baxter Bioscience, Vienna, Member of WHO Commission * Lecturer, PTS Coach, Employer of IMC-Graduates 18:20 Ex vivo Deconstruction of the Stem Cell Niche in Human Interfollicular Epidermis G. Walko, Dr. King's College London, School of Medicine, Centre for Stem Cells and Regenerative Medicine *Lecturer 19:15 Heuriger Müllner Students, Lecturers, Coaches and R&D Partners

5 March 26, 2014 Room: Int. Conf. Hall, IMC FH Krems 9:00 Opening Ceremony of the International Conference BioNanoMed Chair: D. Falkenhagen, Univ.-Prof. Dr. Biotec Area Krems and Danube University Krems H. Hundsberger, Prof.(FH) Dr. Department of Biotechnology, IMC University of Applied Sciences Krems and Biotec Area Krems Plenary Lectures 9:20 Nanomedicine Becomes Reality in Europe P. Boisseou, Prof. Dr. CEA-Leti, Business Development Nanomedicine, Chairmen of European technology Platform Nanomedicine (ETPN), Grenoble (France) 10:00 Neurogenic and Tolerogenic LIF-Nanotherapy to Support Primary Human Fetal Cell Transplants for Parkinson s Disease Su Metcalfe, Dr. Department of Neurology, Brain Repair Centre, University of Cambridge 10:15 Investigating Sialic Acid-Functionalized Nanoparticles as a Novel Anti- InflammatoryTherapy Baljinder Bains, Dr. Queen s University, Molecular Therapeutics Group, Belfast 10:30 TiO2 Nanoparticles Stimulate Human Peripheral Blood Mononuclear Cells D. Fuchs, Dr. Biocenter Innsbruck, Division of Biological Chemistry, Medical University Innsbruck 10:45 Novel Thermoresponsive Polymer Coatings for Controlling Cell Behavior C. Duschl, Dr. Fraunhofer Institut für Biomedizinische Technik, Potsdam 11:00 Break Room: Main Lecture Hall, FH Krems

6 11:10 Artificial Organs. When the Movies were Young! J. Vienken, Prof. Dr. * Lecturer, PTS-Coach, Member of Scientific Advisory Board of Dept. Biotechnology 11:50 Lunch Break Session: Medical Biotechnology Chair: Rahaf Qamou and Stefan Lichtenberger, Biotech Students 12:30 Cartilage Repair Do we need Cells? St. Nehrer, Univ.-Prof. Dr. Dean, Danube University Krems * Lecturer, PTS-Coach 12:50 Cardiac Tissue Scar Remodeling and Ventricular Support after Bioactive Implant Application in Sheep C. E. Semino, Univ.-Prof. Dr. IQS-School of Engineering, Bioengineering Department, Ramon Llull University, Barcelona * Lecturer, PTS-Coach Polymers for Extracorporeal Blood Purification: Relation between Physico-chemical Properties and Blood Compatibility V. Weber, Prof. Dr. Vice Rector of Danube University Krems * Lecturer, PTS- and PhD-Coach, Employer of IMC-Graduates, R&D Partner 13:30 How can we Overcome the Stagnation in Artificial Liver Support D. Falkenhagen, Prof. Dr. and S. Harm, J. Hartmann, Former Head of Dept. Clinical Medicine & Biotechnology, Danube University Krems * Co-Initiator of the Biotechnology Program, Lecturer, PTS- and PhD-Coach, Employer of IMC-Graduates, R&D Partner 13:50 New Adsorber for the Effective Treatment of Severe Asthma Patients when Standard Therapies do not Help H.-P. Leinenbach, Dr. Head of R&D, Fresenius Medical Care Adsorber Tec GmbH, Krems * PTS Coach, R&D Partner 14:10 Ageing: Biology and Pathology H. Nizze, Univ.-Prof. Dr. Former Head of Institute of Pathology, University of Rostock 14:30 Break Session: Pharmaceutical Biotechnology Chair: Raimond Stroe and Kerstin Wiegand, Biotech Students 15:00 Manufacturing of Human Blood Plasma Derived Pharmaceuticals K. Hofbauer Prof. DI. Baxter Bioscience, Plasma Manufacturing Vienna & Support CE, Vienna 15:20 Advancing Novel Antibody Biologics F. Rüker, Prof. DI Dr. University of Natural Resources and Life Sciences, Vienna

7 15:40 Next Generation of Allergy Vaccines F. Ferreira, Prof. Dr. Vice Rector for Research, University Salzburg 16:00 Nanofiltration A. Jungbauer, Univ.-Prof. Dr. University of Natural Resources and Life Sciences, Vienna *Member of Scientific Advisory Board of Dept. Biotechnology 16:20 Enzymes Based Strategies in Medical Applications G. Gübitz, Univ.-Prof. Dr. University of Natural Resources and Life Sciences, Inst. Environmental Ecology, Tulln *Lecturer 16:40 Concepts for Integrated Bioprocess Design T. Langemann Dr., Ch. Herwig, Univ.-Prof. Dr. Vienna University of Technology, Research Area Biochemical Engineering *Lecturer 17:00 Watching Molecules Interact: Biophysical Methods in Drug Discovery K. Rumpel, Dr. Lab Leader, Structural Research, FEC, Boehringer-Ingelheim, RCV Vienna 17:20 Coffee Break Krems Graduates in Industry and Universities Chair: U. Schlokat, Prof. (FH), Dr., Kuala Lumpur Sentinext Therapeutics; Director at Board Sentinext Mediomics (Portugal) and PRiME Biologics (Singapore) 18:00 Being a Drug Safety Officer at Octapharma St. März, Dr. OctaPharma, Vienna 18:15 Translational Research in Cardiac Surgery I. Werner, Dr., Johann Wolfgang Goethe University, Frankfurt 18:30 Validation of Multiplex Detection of Inflammatory Mediators Using the New Hybcell Technology A. Schildberger, Dr. Christian Doppler Laboratory for Innovative Therapy Approaches in Sepsis, Danube University Krems 18:45 Neuroscience in the 21st Century J.Passecker, Dr. Medical University Vienna

8 Experiences presented by Graduates: (to be continued at the following Dinner) R. Fedra, VELALabs, Vienna Ch. Kefeder, AGES Vienna C. Deinhammer, Fresenius Medical Care, Krems F. Astelbauer, Baxter, Vienna N. Gredelj, Eppendorf AG, Hamburg D. Rainer, PhD-Stud., University Graz S. Wöckinger, Nycomed, Linz K. Kaineder, Vienna St. Schwarzmair, ArsElectronica Center, Vienna M. Hirschler, Baxter Bioscience, Vienna B. Robl, PhD-Stud., Medical University Vienna T. Block, Baxter Vienna A. Koppensteiner, IMC Krems 18:45 Meeting of the International Scientific Advisory Board Department of Biotechnology 19:30 Dinner with the Graduates, Lecturers and Guests at the Heuriger Siedler March 27 and 28, :00 17:00 Room: Int. Conf. Hall, IMC FH Krems BioNanoMed International Conference Attendance of all Biotech Students See Program: IMC BioTeam: H. Hundsberger, A. Eger, B. Entler, D. Mezricky, M. Pflüger, D. Schild, B. Klausgraber, E. Hofmann, C. Klein, N. Jacobi, E. Garschall, P. Lang, K. Lichtenwagner and W. Schütt (em.) Information: *) Partnership of lecturers with students and team of the Department of Biotechnology