Big Data Medical Imaging. Brett Cowan Centre for Advanced MRI University of Auckland

Size: px
Start display at page:

Download "Big Data Medical Imaging. Brett Cowan Centre for Advanced MRI University of Auckland"

Transcription

1 Big Data Medical Imaging Brett Cowan Centre for Advanced MRI University of Auckland

2 Overview Medical Imaging 2/40 1. Medical imaging and Big Data Medical imaging is producing huge quantities of complex and high quality data what do we do with it all? 2. Big Data in action the Cardiac Atlas Project International collaboration, data ownership, data sharing and infrastructure 3. Data Analysis New statistical analyses of shape, disease classifiers, and new and improved diagnostic accuracy 4. A new approach to clinical trials? Can we get more for less out of international clinical trials?

3 Magnetic Resonance Imaging (MRI) Medical Imaging 3/40 in just 20 years, MRI has revolutionised medical imaging without radiation, without any known harmful effects and without even touching the patient, MRI produces diagnostic images of virtually photographic quality the Auckland District Health Board PACS system has 15 TB on-line (one year of imaging), 27 TB near-line (3 years of imaging) and 40 TB off-line ten years ago, one year of imaging was <1 TB, now it is 15 TB

4 Faster Image Acquisition Medical Imaging 4/ FLASH (25 seconds) 2005 SSFP (14 seconds) 2010 Accelerated (5 seconds) 2013 Realtime (1 second)

5 Neurological MRI Medical Imaging 5/40 T1 weighted T2 weighted

6 Tractography and fmri Medical Imaging 6/40 Tractography fmri

7 Data or Information or Knowledge? Medical Imaging 7/40 in medical imaging, the data are usually grey scale pixel values they are not demographics (52 years old), blood pressure (155/95), a genetic sequence (ACAT), they are just numbers representing grey scale (or colour) in an image this data is not information in the sense of many other datasets we must align images into a common reference frame, segment features of interest, measure distances, thickness, volume and define shapes or regions of interest this process is time consuming relative to scan acquisition time (the acquisition to analysis ratio)

8 Image Processing Medical Imaging 8/40 Edge detection Non-rigid registration Feature tracking a wide range of image processing techniques are used such as machine learning, finite element modeling - and human interaction these are computationally (or time) intensive

9 The Cardiac Atlas Project (CAP) CAP Project 9/40 collecting data is expensive and it is reusable the cardiac atlas project (CAP) is an international Big Data project funded by the NIH, led from Auckland subcontracts were awarded to collaborators at Johns Hopkins, UCLA, and a Los Angeles supercomputing centre (Centre for Computational Biology) aim to collate cardiac (image) data from large international clinical trials into a web accessible big data database for reuse by any legitimate researcher other aims were to create an infrastructure for managing approval for data use. and to create advanced statistical analysis and display tools the first two contributing clinical trials were the MESA and DETERMINE trials Fonseca et al. Bioinformatics 27(16): ; 2011

10 CAP Project Case Study CAP Project 10/40 1. The overall rationale and strategy 2. Ownership of data 3. Project infrastructure 4. Data analysis and results

11 The Big Data Strategy CAP Project 11/40 Data Acquisition RADIOLOGY Heart Modelling BIOENGINEERING Patient Diagnosis MEDICINE Statistical Analysis BIG DATA Software Development COMPUTER SCIENCE

12 Ownership and Rights to Big Data CAP Project 12/40

13 Data Ownership Data Has Value CAP Project 13/40 Who owns the rights to medical imaging trial data? Who can use it and for what purpose? Participant has rights, certainly they must provide informed consent, informed in that they fully understand the risks and benefits, and what the information will be used for ethics committees will not usually give permission for the data to be used by anyone for anything in the future Researcher has rights, often jealously guarded as a strategic advantage for publication and career progression Institution has rights, but what is an individual leaves the University, do they have the right to take all of the data with them? Funder has rights, especially when they are a commercial entity such as Big Pharma, or if there are valuable patents at stake

14 Ethical Approval (IRB) CAP Project 14/40 Individual consent required Application to IRB required Investigator can make the decision Not human subjects research Low IRB requirements High

15 HIPAA and Anonymisation of Metadata CAP Project 15/40 the convenience and power of electronic data is also its Achilles heel the DICOM standard allows for the inclusion of private information, which is not HIPAA (1996) compliant in many cases.

16 Project Infrastructure CAP Project 16/40

17 Database CAP Project 17/40

18 Calculation of Volume and Mass CAP Project 18/40 Complete mathematical representation of the left ventricle

19 Creation of a Mathematical Model CAP Project 19/40 Using image processing (and operator input), the raw images are converted into a beating mathematical heart in the database. This allows any parameter to be determined without further analysis.

20 Reproducibility and Accuracy CAP Project 20/40 Scan rescan variability 25 patients with moderate to severe MR Scanned twice at a six week interval Coefficient of variation 3% LVM difference -1.1 ± 5.7 g (~ 0.6%) Accuracy 12 animals (9 dogs, 3 pigs) Data courtesy David Fieno and Paul Finn LVM determined by weight at autopsy LVM difference 2.1 ± 4.3 g (~3%) Difference (g) Difference (g) Average LVM (g) Postmortem (g)

21 Segmentation Challenge CAP Project 21/40 (a) Basal slice (b) Mid-ventricular slice (c) Apical slice Suinesiaputra et al. Medical Image Analysis In press 2013

22 Modal Analysis CAP Project 22/40 Lewandowski et al. Circulation 2013;127:

23 Identification of Myocardial Infarction CAP Project 23/40 Anterior Lateral Septal L L L P A P A P A S S S Medrano-Gracia et al. JCMR 15:80 ; 2013

24 Modeling of Stiffness, Stress and Strain CAP Project 24/40 Normal Non-Ischaemic HF Vicky Wang, Martyn Nash, STACOM

25 Classification of Disease CAP Project 25/40 Does the patient have the disease?? Medrano-Gracia, PhD thesis, 2013

26 Data Analysis CAP Project 26/40 How bad is the disease?? Medrano-Gracia, PhD thesis, 2013

27 A Second Example the Coronary Arteries CAP Project 27/40 Image data Clinical problem Database Statistics

28 Catalonia Prospective trials 28/40

29 Cardiovascular Risk in Catalonia Prospective trials 29/40 If we wanted to determine the cardiovascular risk profile in Catalonia, how would we do this? Specific Generic 1. Recruit 5,000 normal Catalonians (preferably in 1948) and follow them for 50 years (similar to the definitive Framingham study) 2. Recruit 5,000 normal Catalonians and follow them for five years (an abbreviated Framingham study) 3. Use the Framingham results and add local correction factors from small studies where there are obvious discrepancies 4. Read the Framingham publications and speculate on how the data applies locally High cost Low cost

30 The VERIFICA Study Prospective trials 30/40 The Framingham function adapted to local population characteristics accurately and reliably predicted the 5-year CHD risk for patients aged years, in contrast with the original function, which consistently overestimated the actual risk. about 60% was observed in the United Kingdom; however, this is far from the >260% overestimation observed in Spain

31 The Catalonian Risk Table Prospective trials 31/40

32 Cost-Benefit Ratio of Clinical Trials Prospective trials 32/40 Cost Benefit Not fundable Fundable NZ Specific data Generic data Trial performed in New Zealand Can we do better in this range? Trial performed Overseas

33 The MESA Trial Prospective trials 33/40 The Multi-Ethnic Study of Atherosclerosis (MESA) is a study of the characteristics of subclinical cardiovascular disease and the risk factors that predict progression to clinical disease. 6,814 asymptomatic men and women aged have been recruited. (38% are white, 28% African- American, 22% Hispanic, and 12% Asian).

34 MESA Investigations Prospective trials 34/40 extensive physical exam to determine coronary calcification ventricular mass and function by MRI flow-mediated endothelial vasodilation carotid intimal-medial wall thickness and presence of echogenic lucencies in the carotid artery lower extremity vascular insufficiency arterial wave forms electrocardiographic (ECG) measures standard coronary risk factors socio-demographic factors lifestyle factors, and psychosocial factors blood samples are being assayed for putative biochemical risk factors and stored for case-control studies DNA are being extracted and lymphocytes immortalized for study of candidate genes and possibly, genome-wide scanning participants are being followed for identification and characterization of cardiovascular disease events, including acute myocardial infarction and other forms of coronary heart disease (CHD), stroke, and congestive heart failure; for cardiovascular disease interventions; and for mortality

35 The Jackson Heart Study Prospective trials 35/40 The objective of the Jackson Heart Study is to investigate the causes of cardiovascular disease (CVD) in African Americans (n=5301) with an emphasis on manifestations related to hypertension (such as remodeling of the left ventricle of the heart, coronary artery disease, heart failure, stroke and renal vascular disease). The MESA and Jackson Heart Studies are using software developed in Auckland to analyse all of their cardiac MRI image data. The data and results are fully compatible with all of the work already done here.

36 New Zealand Fingerprinting Prospective trials 36/40 could we perform the baseline MESA investigations on a group of 100 participants in New Zealand? this group could be defined geographically, by age, gender, a specific risk factor,. this would provide a mean and standard deviation for each investigation there would also be a profile for each individual participant together these data would represent a fingerprint for this group in New Zealand it is highly likely that some participants (and groups of participants) in MESA will have a similar group (and individual) fingerprint could we then follow them in the MESA trial?

37 Matching Prospective trials 37/40 Fingerprinting Matching n =100 n =1000

38 Future Overall of Clinical Trials Prospective trials 38/40 Outcomes for New Zealand data which reflects NZ subgroups direct application of results amplification of sample size by 10 X trial cost met internationally prospective study design international collaboration and engagement development of fingerprinting and matching technologies 20 year outcomes 15 year outcomes 10 year outcomes 5 year outcomes NZ cohort followed in trial New Zealand Sample (n=100) Fingerprint Statistical matching NZ cohort identified in baseline data (n=1000) Local (New Zealand) Global

39 Big Data Summary 39/40 What is big data for us in Medical Imaging? it is large and expanding medical imaging databases, preferably shared internationally there are issues of data ownership, appropriate ethical consents, data anonymisation and access control computationally intensive image processing is required to convert data into useful information computational and statistical anatomy and pathology (rather than feature labeling, or calculation of simple distance or volumes) image data may be represented using mathematical models to recreate physiological and pathophysiological shape, features and motion statistical analyses of shape, disease classifiers, calculation of new parameters (like stress) become possible clinical trial focus devices and pharmaceuticals

40 Thank you to - Summary 40/40 Alistair Young Avan Michael Jae Do Randall Carissa Lana Agustín Ben John Yingmin Pau Wenchao Paul Finn

2016 PQRS OPTIONS FOR INDIVIDUAL MEASURES: CLAIMS, REGISTRY

2016 PQRS OPTIONS FOR INDIVIDUAL MEASURES: CLAIMS, REGISTRY Measure #317: Preventive Care and Screening: Screening for High Blood Pressure and Follow-Up Documented National Quality Strategy Domain: Community / Population Health 2016 PQRS OPTIONS F INDIVIDUAL MEASURES:

More information

Cohort Studies. Sukon Kanchanaraksa, PhD Johns Hopkins University

Cohort Studies. Sukon Kanchanaraksa, PhD Johns Hopkins University This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this

More information

Specific Basic Standards for Osteopathic Fellowship Training in Cardiology

Specific Basic Standards for Osteopathic Fellowship Training in Cardiology Specific Basic Standards for Osteopathic Fellowship Training in Cardiology American Osteopathic Association and American College of Osteopathic Internists BOT 07/2006 Rev. BOT 03/2009 Rev. BOT 07/2011

More information

Coronary Artery Disease leading cause of morbidity & mortality in industrialised nations.

Coronary Artery Disease leading cause of morbidity & mortality in industrialised nations. INTRODUCTION Coronary Artery Disease leading cause of morbidity & mortality in industrialised nations. Although decrease in cardiovascular mortality still major cause of morbidity & burden of disease.

More information

Systolic Blood Pressure Intervention Trial (SPRINT) Principal Results

Systolic Blood Pressure Intervention Trial (SPRINT) Principal Results Systolic Blood Pressure Intervention Trial (SPRINT) Principal Results Paul K. Whelton, MB, MD, MSc Chair, SPRINT Steering Committee Tulane University School of Public Health and Tropical Medicine, and

More information

Magnetic Resonance Quantitative Analysis. MRV MR Flow. Reliable analysis of heart and peripheral arteries in the clinical workflow

Magnetic Resonance Quantitative Analysis. MRV MR Flow. Reliable analysis of heart and peripheral arteries in the clinical workflow Magnetic Resonance Quantitative Analysis MRV MR Flow Reliable analysis of heart and peripheral arteries in the clinical workflow CAAS MRV Functional Workflow Designed for imaging specialists, CAAS MRV

More information

STROKE April 2011 Dr Amer Jafar A delay in recognizing early warning signs (WS) and risk factors (RF) of ischemic stroke causes a delay in treatment Evaluated: knowledge of RF and WS and the impact of

More information

THE INTERNET STROKE CENTER PRESENTATIONS AND DISCUSSIONS ON STROKE MANAGEMENT

THE INTERNET STROKE CENTER PRESENTATIONS AND DISCUSSIONS ON STROKE MANAGEMENT THE INTERNET STROKE CENTER PRESENTATIONS AND DISCUSSIONS ON STROKE MANAGEMENT Stroke Prevention in Atrial Fibrillation Gregory Albers, M.D. Director Stanford Stroke Center Professor of Neurology and Neurological

More information

DISCLOSURES RISK ASSESSMENT. Stroke and Heart Disease -Is there a Link Beyond Risk Factors? Daniel Lackland, MD

DISCLOSURES RISK ASSESSMENT. Stroke and Heart Disease -Is there a Link Beyond Risk Factors? Daniel Lackland, MD STROKE AND HEART DISEASE IS THERE A LINK BEYOND RISK FACTORS? D AN IE L T. L AC K L AN D DISCLOSURES Member of NHLBI Risk Assessment Workgroup RISK ASSESSMENT Count major risk factors For patients with

More information

Main Effect of Screening for Coronary Artery Disease Using CT

Main Effect of Screening for Coronary Artery Disease Using CT Main Effect of Screening for Coronary Artery Disease Using CT Angiography on Mortality and Cardiac Events in High risk Patients with Diabetes: The FACTOR-64 Randomized Clinical Trial Joseph B. Muhlestein,

More information

Version 1 2015. Module guide. Preliminary document. International Master Program Cardiovascular Science University of Göttingen

Version 1 2015. Module guide. Preliminary document. International Master Program Cardiovascular Science University of Göttingen Version 1 2015 Module guide International Master Program Cardiovascular Science University of Göttingen Part 1 Theoretical modules Synopsis The Master program Cardiovascular Science contains four theoretical

More information

SECTION I: Request. SECTION II: Need. Program Description

SECTION I: Request. SECTION II: Need. Program Description SECTION I: Request This is a formal request for the Utah CARMA Center to be formally recognized by the University of Utah as a large, collaborative medical and academic center whose focus is on comprehensive

More information

RITMIR024 - STEM CELL RESEARCH IN CARDIOLOGY

RITMIR024 - STEM CELL RESEARCH IN CARDIOLOGY 1. SCOPE AND METHODOLOGY 2. REPORT SYNOPSIS 2.1 General Definitions Myoblasts Pluripotent Cells Multipotent Cells Progenitor Cells Role of Stem Cells in Repairing the Heart Stem Cell Therapy Stem Cells

More information

MYOCARDIAL PERFUSION COMPUTED TOMOGRAPHY PhD course in Medical Imaging. Anne Günther Department of Radiology OUS Rikshospitalet

MYOCARDIAL PERFUSION COMPUTED TOMOGRAPHY PhD course in Medical Imaging. Anne Günther Department of Radiology OUS Rikshospitalet MYOCARDIAL PERFUSION COMPUTED TOMOGRAPHY PhD course in Medical Imaging Anne Günther Department of Radiology OUS Rikshospitalet CORONARY CT ANGIOGRAPHY (CTA) Accurate method in the assessment of possible

More information

UNIVERSITY OF MEDICINE AND PHARMACY CRAIOVA DOCTORAL SCHOOL DOCTORATE THESIS. - Summary

UNIVERSITY OF MEDICINE AND PHARMACY CRAIOVA DOCTORAL SCHOOL DOCTORATE THESIS. - Summary UNIVERSITY OF MEDICINE AND PHARMACY CRAIOVA DOCTORAL SCHOOL DOCTORATE THESIS - Summary CHRONIC COMPLICATIONS IN PATIENTS WITH TYPE 1 DIABETES MELLITUS - Epidemiological study - PhD Manager: Professor PhD.

More information

COMMITTEE FOR HUMAN MEDICINAL PRODUCTS (CHMP) DRAFT GUIDELINE ON THE EVALUATION OF MEDICINAL PRODUCTS FOR CARDIOVASCULAR DISEASE PREVENTION

COMMITTEE FOR HUMAN MEDICINAL PRODUCTS (CHMP) DRAFT GUIDELINE ON THE EVALUATION OF MEDICINAL PRODUCTS FOR CARDIOVASCULAR DISEASE PREVENTION European Medicines Agency London, 19 July 2007 Doc. Ref. EMEA/CHMP/EWP/311890/2007 COMMITTEE FOR HUMAN MEDICINAL PRODUCTS (CHMP) DRAFT GUIDELINE ON THE EVALUATION OF MEDICINAL PRODUCTS FOR CARDIOVASCULAR

More information

Stress is linked to exaggerated cardiovascular reactivity. 1) Stress 2) Hostility 3) Social Support. Evidence of association between these

Stress is linked to exaggerated cardiovascular reactivity. 1) Stress 2) Hostility 3) Social Support. Evidence of association between these Psychosocial Factors & CHD Health Psychology Psychosocial Factors 1) Stress 2) Hostility 3) Social Support Evidence of association between these psychosocial factors and CHD Physiological Mechanisms Stress

More information

COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE (CHMP) GUIDELINE ON THE EVALUATION OF MEDICINAL PRODUCTS FOR CARDIOVASCULAR DISEASE PREVENTION

COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE (CHMP) GUIDELINE ON THE EVALUATION OF MEDICINAL PRODUCTS FOR CARDIOVASCULAR DISEASE PREVENTION European Medicines Agency Pre-Authorisation Evaluation of Medicines for Human Use London, 25 September 2008 Doc. Ref. EMEA/CHMP/EWP/311890/2007 COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE (CHMP) GUIDELINE

More information

Absolute cardiovascular disease risk assessment

Absolute cardiovascular disease risk assessment Quick reference guide for health professionals Absolute cardiovascular disease risk assessment This quick reference guide is a summary of the key steps involved in assessing absolute cardiovascular risk

More information

Prevention of Cardiovascular Disease in Children with Diabetes

Prevention of Cardiovascular Disease in Children with Diabetes Prevention of Cardiovascular Disease in Children with Diabetes Stephen R. Daniels, MD, PhD Department of Pediatrics University of Colorado School of Medicine The Children s Hospital Anschutz Medical Campus

More information

Diagnostic and Therapeutic Procedures

Diagnostic and Therapeutic Procedures Diagnostic and Therapeutic Procedures Diagnostic and therapeutic cardiovascular s are central to the evaluation and management of patients with cardiovascular disease. Consistent with the other sections,

More information

Image Area. View Point. Medical Imaging. Advanced Imaging Solutions for Diagnosis, Localization, Treatment Planning and Monitoring. www.infosys.

Image Area. View Point. Medical Imaging. Advanced Imaging Solutions for Diagnosis, Localization, Treatment Planning and Monitoring. www.infosys. Image Area View Point Medical Imaging Advanced Imaging Solutions for Diagnosis, Localization, Treatment Planning and Monitoring www.infosys.com Over the years, medical imaging has become vital in the early

More information

Detection of Heart Diseases by Mathematical Artificial Intelligence Algorithm Using Phonocardiogram Signals

Detection of Heart Diseases by Mathematical Artificial Intelligence Algorithm Using Phonocardiogram Signals International Journal of Innovation and Applied Studies ISSN 2028-9324 Vol. 3 No. 1 May 2013, pp. 145-150 2013 Innovative Space of Scientific Research Journals http://www.issr-journals.org/ijias/ Detection

More information

The Role of Insurance in Providing Access to Cardiac Care in Maryland. Samuel L. Brown, Ph.D. University of Baltimore College of Public Affairs

The Role of Insurance in Providing Access to Cardiac Care in Maryland. Samuel L. Brown, Ph.D. University of Baltimore College of Public Affairs The Role of Insurance in Providing Access to Cardiac Care in Maryland Samuel L. Brown, Ph.D. University of Baltimore College of Public Affairs Heart Disease Heart Disease is the leading cause of death

More information

Preparation iagnostic Medical Sonographer Overview"

Preparation iagnostic Medical Sonographer Overview Diagnostic Medical Sonographer Overview The Field - Preparation - Specialty Areas - Day in the Life - Earnings - Employment - Career Path Forecast - Professional Organizations The Field Diagnostic imaging

More information

NHS Imaging and Radiodiagnostic activity in England. 2012/13 Release. August 2013

NHS Imaging and Radiodiagnostic activity in England. 2012/13 Release. August 2013 NHS Imaging and Radiodiagnostic activity in England 2012/13 Release August 2013 Commentary This National Statistics release covers Imaging and Radiodiagnostic examinations or tests carried out in the NHS

More information

Measure #236 (NQF 0018): Controlling High Blood Pressure National Quality Strategy Domain: Effective Clinical Care

Measure #236 (NQF 0018): Controlling High Blood Pressure National Quality Strategy Domain: Effective Clinical Care Measure #236 (NQF 0018): Controlling High Blood Pressure National Quality Strategy Domain: Effective Clinical Care 2016 PQRS OPTIONS F INDIVIDUAL MEASURES: CLAIMS, REGISTRY DESCRIPTION: Percentage of patients

More information

Listen to your heart: Good Cardiovascular Health for Life

Listen to your heart: Good Cardiovascular Health for Life Listen to your heart: Good Cardiovascular Health for Life Luis R. Castellanos MD, MPH Assistant Clinical Professor of Medicine University of California San Diego School of Medicine Sulpizio Family Cardiovascular

More information

HeAT: A Software Assistant for the Analysis of LV Remodeling after Myocardial Infarction in 4D MR Follow-Up Studies

HeAT: A Software Assistant for the Analysis of LV Remodeling after Myocardial Infarction in 4D MR Follow-Up Studies HeAT: A Software Assistant for the Analysis of LV Remodeling after Myocardial Infarction in 4D MR Follow-Up Studies D. Säring 1, A. Stork 2, S. Juchheim 2, G. Lund 3, G. Adam 2, H. Handels 1 1 Department

More information

Osama Jarkas. in Chest Pain Patients. STUDENT NAME: Osama Jarkas DATE: August 10 th, 2015

Osama Jarkas. in Chest Pain Patients. STUDENT NAME: Osama Jarkas DATE: August 10 th, 2015 STUDENT NAME: Osama Jarkas DATE: August 10 th, 2015 PROJECT TITLE: Analysis of ECG Exercise Stress Testing and Framingham Risk Score in Chest Pain Patients PRIMARY SUPERVISOR NAME: Dr. Edward Tan DEPARTMENT:

More information

Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults. Learn and Live SM. ACCF/AHA Pocket Guideline

Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults. Learn and Live SM. ACCF/AHA Pocket Guideline Learn and Live SM ACCF/AHA Pocket Guideline Based on the 2010 ACCF/AHA Guideline Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults November 2010 Guideline for Assessment of Cardiovascular

More information

U.S. Bureau of Labor Statistics. Radiology Tech

U.S. Bureau of Labor Statistics. Radiology Tech From the: U.S. Bureau of Labor Statistics Radiology Tech What They Do Radiologic technologists (RTs) perform diagnostic imaging examinations, such as x rays, on patients. Duties RTs typically do the following:

More information

HeartScore Web - based version users guide TABLE OF CONTENTS. 1. Preamble... 2. 2. Benefits of using HeartScore... 2. 3. Accessing HeartScore...

HeartScore Web - based version users guide TABLE OF CONTENTS. 1. Preamble... 2. 2. Benefits of using HeartScore... 2. 3. Accessing HeartScore... TABLE OF CONTENTS 1. Preamble... 2 2. Benefits of using HeartScore... 2 3. Accessing HeartScore... 2 4. HeartScore Web Based Homepage... 3 5. Patient Card... 4 6. Create a new examination... 6 7. Examination

More information

Majestic Trial 12 Month Results

Majestic Trial 12 Month Results Majestic Trial 12 Month Results S.Müller-Hülsbeck, MD, EBIR, FCIRSE, FICA ACADEMIC HOSPITALS Flensburg of Kiel University Ev.-Luth. Diakonissenanstalt zu Flensburg Knuthstraße 1, 24939 FLENSBURG Dept.

More information

Whitepapers on Imaging Infrastructure for Research Paper 1. General Workflow Considerations

Whitepapers on Imaging Infrastructure for Research Paper 1. General Workflow Considerations Whitepapers on Imaging Infrastructure for Research Paper 1. General Workflow Considerations Bradley J Erickson, Tony Pan, Daniel J Marcus, CTSA Imaging Informatics Working Group Introduction The use of

More information

EDITORIAL MINING FOR GOLD : CAPITALISING ON DATA TO TRANSFORM DRUG DEVELOPMENT. A Changing Industry. What Is Big Data?

EDITORIAL MINING FOR GOLD : CAPITALISING ON DATA TO TRANSFORM DRUG DEVELOPMENT. A Changing Industry. What Is Big Data? EDITORIAL : VOL 14 ISSUE 1 BSLR 3 Much has been written about the potential of data mining big data to transform drug development, reduce uncertainty, facilitate more targeted drug discovery and make more

More information

CHAPTER 9 DISEASES OF THE CIRCULATORY SYSTEM (I00-I99)

CHAPTER 9 DISEASES OF THE CIRCULATORY SYSTEM (I00-I99) CHAPTER 9 DISEASES OF THE CIRCULATORY SYSTEM (I00-I99) March 2014 2014 MVP Health Care, Inc. CHAPTER 9 CHAPTER SPECIFIC CATEGORY CODE BLOCKS I00-I02 Acute rheumatic fever I05-I09 Chronic rheumatic heart

More information

Open & Big Data for Life Imaging Technical aspects : existing solutions, main difficulties. Pierre Mouillard MD

Open & Big Data for Life Imaging Technical aspects : existing solutions, main difficulties. Pierre Mouillard MD Open & Big Data for Life Imaging Technical aspects : existing solutions, main difficulties Pierre Mouillard MD What is Big Data? lots of data more than you can process using common database software and

More information

Emory University RT to Bachelor of Medical Science Degree Medical Imaging

Emory University RT to Bachelor of Medical Science Degree Medical Imaging Emory University RT to Bachelor of Medical Science Degree Medical Imaging Courses: All RT-BMSc students must complete all of the program s core courses and the courses specific to their selected minor

More information

New Cholesterol Guidelines: Carte Blanche for Statin Overuse Rita F. Redberg, MD, MSc Professor of Medicine

New Cholesterol Guidelines: Carte Blanche for Statin Overuse Rita F. Redberg, MD, MSc Professor of Medicine New Cholesterol Guidelines: Carte Blanche for Statin Overuse Rita F. Redberg, MD, MSc Professor of Medicine Disclosures & Relevant Relationships I have nothing to disclose No financial conflicts Editor,

More information

FACULTY OF ALLIED HEALTH SCIENCES

FACULTY OF ALLIED HEALTH SCIENCES FACULTY OF ALLIED HEALTH SCIENCES 102 Naresuan University FACULTY OF ALLIED HEALTH SCIENCES has focused on providing strong professional programs, including Medical established as one of the leading institutes

More information

M110.726 The Nucleus M110.727 The Cytoskeleton M340.703 Cell Structure and Dynamics

M110.726 The Nucleus M110.727 The Cytoskeleton M340.703 Cell Structure and Dynamics of Biochemistry and Molecular Biology 1. Master the knowledge base of current biochemistry, molecular biology, and cellular physiology Describe current knowledge in metabolic transformations conducted

More information

Use of Glycated Hemoglobin and Microalbuminuria in the Monitoring of Diabetes Mellitus

Use of Glycated Hemoglobin and Microalbuminuria in the Monitoring of Diabetes Mellitus Agency for Healthcare Research and Quality Evidence Report/Technology Assessment Number 84 Use of Glycated Hemoglobin and Microalbuminuria in the Monitoring of Diabetes Mellitus Summary Overview Clinical

More information

Q1: Global risk assessment using PROCAM, SCORE, FRAMINGHAM or REYNOLDS ecc is sufficient YES NO NEED MORE DATA DISCUSS within Taskforce Your Comments

Q1: Global risk assessment using PROCAM, SCORE, FRAMINGHAM or REYNOLDS ecc is sufficient YES NO NEED MORE DATA DISCUSS within Taskforce Your Comments Site ID: Q1: Global risk assessment using PROCAM, SCORE, FRAMINGHAM or REYLDS ecc is sufficient Q2: The value of an emerging test is best assessed using C - statistics Q3: Atherosclerosis imaging may be

More information

Clinical Training for Visage 7 Cardiac. Visage 7

Clinical Training for Visage 7 Cardiac. Visage 7 Clinical Training for Visage 7 Cardiac Visage 7 Overview Example Usage 3 Cardiac Workflow Examples 4 Remove Chest Wall 5 Edit Chest Wall Removal 6 Object Display Popup 7 Selecting Optimal Phase 8 Thick

More information

Journal Club: Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy by the AIM-HIGH Investigators

Journal Club: Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy by the AIM-HIGH Investigators Journal Club: Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy by the AIM-HIGH Investigators Shaikha Al Naimi Doctor of Pharmacy Student College of Pharmacy Qatar University

More information

Christopher M. Wright, MD, MBA Pioneer Cardiovascular Consultants Tempe, Arizona

Christopher M. Wright, MD, MBA Pioneer Cardiovascular Consultants Tempe, Arizona Christopher M. Wright, MD, MBA Pioneer Cardiovascular Consultants Tempe, Arizona Areas to be covered Historical, current, and future treatments for various cardiovascular disease: Atherosclerosis (Coronary

More information

Translating Science to Health Care: the Use of Predictive Models in Decision Making

Translating Science to Health Care: the Use of Predictive Models in Decision Making Translating Science to Health Care: the Use of Predictive Models in Decision Making John Griffith, Ph.D., Associate Dean for Research Bouvé College of Health Sciences Northeastern University Topics Clinical

More information

CARDIO-VASCULAR SYSTEM MODULE. Academic Year 2004-2005 Study Guide

CARDIO-VASCULAR SYSTEM MODULE. Academic Year 2004-2005 Study Guide CARDIO-VASCULAR SYSTEM MODULE Academic Year 2004-2005 Study Guide CVS Objectives At the end of this part of the course the student should be able to recognize: 1. The histology and ultra-structure of the

More information

Prognostic impact of uric acid in patients with stable coronary artery disease

Prognostic impact of uric acid in patients with stable coronary artery disease Prognostic impact of uric acid in patients with stable coronary artery disease Gjin Ndrepepa, Siegmund Braun, Martin Hadamitzky, Massimiliano Fusaro, Hans-Ullrich Haase, Kathrin A. Birkmeier, Albert Schomig,

More information

BASIC STANDARDS FOR RESIDENCY TRAINING IN CARDIOLOGY

BASIC STANDARDS FOR RESIDENCY TRAINING IN CARDIOLOGY BASIC STANDARDS FOR RESIDENCY TRAINING IN CARDIOLOGY American Osteopathic Association and the American College of Osteopathic Internists Specific Requirements For Osteopathic Subspecialty Training In Cardiology

More information

GUIDE TO SETTING UP AN MRI RESEARCH PROJECT

GUIDE TO SETTING UP AN MRI RESEARCH PROJECT GUIDE TO SETTING UP AN MRI RESEARCH PROJECT Formal requirements and procedures OVERVIEW This document is intended to help a principle investigator set up a research project using magnetic resonance imaging

More information

DIAGNOSTIC CRITERIA OF STROKE

DIAGNOSTIC CRITERIA OF STROKE DIAGNOSTIC CRITERIA OF STROKE Diagnostic criteria are used to validate clinical diagnoses. Here below MONICA diagnostic criteria are reported. MONICA - MONItoring trends and determinants of CArdiovascular

More information

Imaging of Thoracic Endovascular Stent-Grafts

Imaging of Thoracic Endovascular Stent-Grafts Imaging of Thoracic Endovascular Stent-Grafts Tariq Hameed, M.D. Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana Disclosures: No relevant financial

More information

Distance Learning Program Anatomy of the Human Heart/Pig Heart Dissection Middle School/ High School

Distance Learning Program Anatomy of the Human Heart/Pig Heart Dissection Middle School/ High School Distance Learning Program Anatomy of the Human Heart/Pig Heart Dissection Middle School/ High School This guide is for middle and high school students participating in AIMS Anatomy of the Human Heart and

More information

Embedded Systems in Healthcare. Pierre America Healthcare Systems Architecture Philips Research, Eindhoven, the Netherlands November 12, 2008

Embedded Systems in Healthcare. Pierre America Healthcare Systems Architecture Philips Research, Eindhoven, the Netherlands November 12, 2008 Embedded Systems in Healthcare Pierre America Healthcare Systems Architecture Philips Research, Eindhoven, the Netherlands November 12, 2008 About the Speaker Working for Philips Research since 1982 Projects

More information

ESC/EASD Pocket Guidelines Diabetes, pre-diabetes and cardiovascular disease

ESC/EASD Pocket Guidelines Diabetes, pre-diabetes and cardiovascular disease Diabetes, prediabetes and cardiovascular disease Classes of recommendations Levels of evidence Recommended treatment targets for patients with diabetes and CAD Definition, classification and screening

More information

Now bring the advantages of digital workflow to cardiology

Now bring the advantages of digital workflow to cardiology CARESTREAM Cardiology PACS Now bring the advantages of digital workflow to cardiology The single system advantage Now there s ONE Solution. 2 A large and growing number of health care facilities are benefiting

More information

First floor, Main Hospital North Services provided 24/7 365 days per year

First floor, Main Hospital North Services provided 24/7 365 days per year First floor, Main Hospital North Services provided 24/7 365 days per year General Radiology (X-ray) Fluoroscopy Ultrasound (Sonography) Nuclear Medicine P.E.T. imaging Computed Tomography (CT scan) Magnetic

More information

Neuroimaging module I: Modern neuroimaging methods of investigation of the human brain in health and disease

Neuroimaging module I: Modern neuroimaging methods of investigation of the human brain in health and disease 1 Neuroimaging module I: Modern neuroimaging methods of investigation of the human brain in health and disease The following contains a summary of the content of the neuroimaging module I on the postgraduate

More information

GENERAL HEART DISEASE KNOW THE FACTS

GENERAL HEART DISEASE KNOW THE FACTS GENERAL HEART DISEASE KNOW THE FACTS WHAT IS Heart disease is a broad term meaning any disease affecting the heart. It is commonly used to refer to coronary heart disease (CHD), a more specific term to

More information

CLINICAL & FINANCIAL BENEFITS OF ECG MANAGEMENT

CLINICAL & FINANCIAL BENEFITS OF ECG MANAGEMENT How Will an ECG Management System with Electronic Storage and Recall Benefit my Facility? ECG management has been available in the industry for over twenty- five years. Until now it has been both expensive

More information

INTRODUCTION TO EECP THERAPY

INTRODUCTION TO EECP THERAPY INTRODUCTION TO EECP THERAPY is an FDA cleared, Medicare approved, non-invasive medical therapy for the treatment of stable and unstable angina, congestive heart failure, acute myocardial infarction, and

More information

Signal-averaged electrocardiography late potentials

Signal-averaged electrocardiography late potentials SIGNAL AVERAGED ECG INTRODUCTION Signal-averaged electrocardiography (SAECG) is a special electrocardiographic technique, in which multiple electric signals from the heart are averaged to remove interference

More information

Imaging of Acute Stroke. Noam Eshkar, M.D New Jersey Neuroscience Institute JFK Medical Center Edison Radiology Group

Imaging of Acute Stroke. Noam Eshkar, M.D New Jersey Neuroscience Institute JFK Medical Center Edison Radiology Group Imaging of Acute Stroke Noam Eshkar, M.D New Jersey Neuroscience Institute JFK Medical Center Edison Radiology Group Modalities Non Contrast CT (NCCT) Contrast CT Angiography MRI MR Angiography Perfusion

More information

EMR Tutorial Acute Coronary Syndrome

EMR Tutorial Acute Coronary Syndrome EMR Tutorial Acute Coronary Syndrome How to find the Acute Coronary Syndrome AAA Home Page 1 of 26 Master Tool Bar Icon When the Template button is clicked you will be presented with the preference list.

More information

GE Healthcare CASE. Cardiac Assessment System for Exercise Testing. Connecting hearts and minds.

GE Healthcare CASE. Cardiac Assessment System for Exercise Testing. Connecting hearts and minds. GE Healthcare CASE Cardiac Assessment System for Exercise Testing Connecting hearts and minds. Stressing better outcomes. Proven clinical excellence. Productivity-enhancing applications and features. Expanded

More information

STUDY PLAN FOR THE CERTIFICATE OF THE HIGHER SPECIALIZATION IN ( Diagnostic Radiology)

STUDY PLAN FOR THE CERTIFICATE OF THE HIGHER SPECIALIZATION IN ( Diagnostic Radiology) STUDY PLAN FOR THE CERTIFICATE OF THE HIGHER SPECIALIZATION IN ( Diagnostic Radiology) plan number :15/11/97/NT I-GENERAL RULES AND CONDITIONS: 1- This plan conforms to the regulations of granting the

More information

Whitehall II Data Collection Procedure Phases 11 and 12

Whitehall II Data Collection Procedure Phases 11 and 12 Whitehall II Data Collection Procedure Phases 11 and 12 Version 2 March 2015 Dr Aida Sanchez With the collaboration of Therese Butler, Beverly Milne, Stephanie Smith Whitehall II Department of Epidemiology

More information

CardioSoft * Diagnostic System

CardioSoft * Diagnostic System GE Healthcare CardioSoft * Diagnostic System Connecting Hearts and Minds Clinically connected. Simply smart. CardioSoft Diagnostic System from GE Healthcare is more than a software program it is a data

More information

Information for patients and the public and patient information about DNA / Biobanking across Europe

Information for patients and the public and patient information about DNA / Biobanking across Europe Information for patients and the public and patient information about DNA / Biobanking across Europe BIOBANKING / DNA BANKING SUMMARY: A biobank is a store of human biological material, used for the purposes

More information

Test Content Outline Effective Date: February 6, 2015. Cardiac-Vascular Nursing Board Certification Examination

Test Content Outline Effective Date: February 6, 2015. Cardiac-Vascular Nursing Board Certification Examination Effective Date: February 6, 2015 Board Certification Examination There are 175 questions on this examination. Of these, 150 are scored questions and 25 are pretest questions that are not scored. Pretest

More information

Acquired, Drug-Induced Long QT Syndrome

Acquired, Drug-Induced Long QT Syndrome Acquired, Drug-Induced Long QT Syndrome A Guide for Patients and Health Care Providers Sudden Arrhythmia Death Syndromes (SADS) Foundation 508 E. South Temple, Suite 202 Salt Lake City, Utah 84102 800-STOP

More information

The Field. Radiologic technologists take x-rays and administer nonradioactive materials into patients' bloodstreams for diagnostic purposes.

The Field. Radiologic technologists take x-rays and administer nonradioactive materials into patients' bloodstreams for diagnostic purposes. Radiologic Technologist Overview The Field - Specialty Areas - Preparation - Day in the Life - Earnings - Employment - Career Path Forecast - Professional Organizations The Field Radiologic technologists

More information

Personalisation of health in HF and CAD patients via closed loop systems

Personalisation of health in HF and CAD patients via closed loop systems Personalisation of health in HF and CAD patients via closed loop systems // Compliance and Effectiveness in HF and CHD Closed loop Management // phealth 2009 Conference - Oslo Sergio Guillén Institute

More information

Māori Pathways to and Through Health Care for STEMIs in New Zealand. Summer Studentship Research by Ellie Tuzzolino- Smith

Māori Pathways to and Through Health Care for STEMIs in New Zealand. Summer Studentship Research by Ellie Tuzzolino- Smith Māori Pathways to and Through Health Care for STEMIs in New Zealand Summer Studentship Research by Ellie Tuzzolino- Smith Terminology & Current Practice STEMI: S-T elevation Myocardial Infarction. Determined

More information

OEM MAXNIBP Frequently Asked Questions

OEM MAXNIBP Frequently Asked Questions Frequently Asked Questions Why does the monitor sometimes inflate the BP cuff, then shortly thereafter reinflate the cuff? How will I know if the monitor is experiencing motion artifact during a measurement?

More information

900 Clock Hours 90 Quarter Credits

900 Clock Hours 90 Quarter Credits Medical Office Management Associate of Applied Science Degree 900 Clock Hours 90 Quarter Credits Course # CouRSE clock Hours Credits MBAS101 Introduction to Medical Administrative Duties 40 4.0 MBAS103

More information

Biotechnical Engineering (BE) Course Description

Biotechnical Engineering (BE) Course Description Biotechnical Engineering (BE) Course Description The major focus of the Biotechnical Engineering TM (BE) course is to expose students to the diverse fields of biotechnology including biomedical engineering,

More information

The VITamin D and OmegA-3 TriaL (VITAL)

The VITamin D and OmegA-3 TriaL (VITAL) The VITamin D and OmegA-3 TriaL (VITAL) JoAnn E. Manson, MD, DrPH Principal Investigator, VITAL Brigham and Women's Hospital Professor of Medicine and the Michael and Lee Bell Professor of Women s Health

More information

NIHI Big Data in Healthcare Research Case Study

NIHI Big Data in Healthcare Research Case Study NIHI Big Data in Healthcare Research Case Study Professor Rob Doughty Heart Foundation Chair of Heart Health National Institute for Health Innovation and the Dept of Medicine, University of Auckland &

More information

990 Clock Hours 91 Quarter Credits

990 Clock Hours 91 Quarter Credits Medical BILLING ADMINISTRATIVE SPECIALISTS PROGRAM 990 Clock Hours 91 Quarter Credits Course # CouRSE clock Hours Credits MBAS101 Introduction to Medical Administrative Duties 40 4.0 MBAS103 Medical Terminology

More information

Cardiovascular Endpoints

Cardiovascular Endpoints The Malmö Diet and Cancer Study Department of Clinical Sciences Malmö University Hospital Lund University The Malmö Diet and Cancer Study CV-cohort Cardiovascular Endpoints End of follow-up: 31 Dec * Report:

More information

Your Guide to Express Critical Illness Insurance Definitions

Your Guide to Express Critical Illness Insurance Definitions Your Guide to Express Critical Illness Insurance Definitions Your Guide to EXPRESS Critical Illness Insurance Definitions This guide to critical illness definitions will help you understand the illnesses

More information

Voxar 3D TM. A suite of advanced visualization and analysis software tools

Voxar 3D TM. A suite of advanced visualization and analysis software tools Voxar 3D TM A suite of advanced visualization and analysis software tools The power to deliver advanced visualization throughout the enterprise To effectively manage the rapid growth of large volumetric

More information

Ultrasound Simulators

Ultrasound Simulators Ultrasound Simulators Tripp Bell, MD University of South Carolina School of Medicine Objectives Give a brief history of simulation in medicine Describe the types of ultrasound simulators Show how ultrasound

More information

The P Wave: Indicator of Atrial Enlargement

The P Wave: Indicator of Atrial Enlargement Marquette University e-publications@marquette Physician Assistant Studies Faculty Research and Publications Health Sciences, College of 8-12-2010 The P Wave: Indicator of Atrial Enlargement Patrick Loftis

More information

BIPOLAR LIMB LEADS UNIPOLAR LIMB LEADS PRECORDIAL (UNIPOLAR) LEADS VIEW OF EACH LEAD INDICATIVE ECG CHANGES

BIPOLAR LIMB LEADS UNIPOLAR LIMB LEADS PRECORDIAL (UNIPOLAR) LEADS VIEW OF EACH LEAD INDICATIVE ECG CHANGES BIPOLAR LIMB LEADS Have both a distinctive positive and negative pole. Lead I LA (positive) RA (negative) Lead II LL (positive) RA (negative) Lead III LL (positive) LA (negative) UNIPOLAR LIMB LEADS Have

More information

ASSOCIATE OF APPLIED SCIENCE IN DIAGNOSTIC MEDICAL SONOGRAPHY (DMS AAS) 130 quarter credit units / 2,160 clock hours / 84 weeks (20-32 hours per

ASSOCIATE OF APPLIED SCIENCE IN DIAGNOSTIC MEDICAL SONOGRAPHY (DMS AAS) 130 quarter credit units / 2,160 clock hours / 84 weeks (20-32 hours per ASSOCIATE OF APPLIED SCIENCE IN DIAGNOSTIC MEDICAL SONOGRAPHY (DMS AAS) 130 quarter credit units / 2,160 clock hours / 84 weeks (20-32 hours per week) Educational Objective: The Associate of Applied Science

More information

Cardiovascular Endpoints

Cardiovascular Endpoints The Malmö Diet and Cancer Study Department of Clinical Sciences Skåne University Hospital, Malmö Lund University The Malmö Diet and Cancer Study CV-cohort Cardiovascular Endpoints End of follow-up: 30

More information

CARDIAC NURSING. Graduate Diploma in Nursing Science. Overview. Entry Requirements. Fees. Contact. Teaching Methods.

CARDIAC NURSING. Graduate Diploma in Nursing Science. Overview. Entry Requirements. Fees. Contact. Teaching Methods. Graduate Diploma in Nursing Science CARDIAC NURSING Overview The Graduate Diploma in Nursing Science (Cardiac Nursing) is designed to develop advanced theoretical knowledge and specialist skills essential

More information

Spirometry, COPD and lung cancer

Spirometry, COPD and lung cancer Spirometry, COPD and lung cancer Associate Professor Robert Young BMedSc, MBChB, DPhil (Oxon), FRACP, FRCP University of Auckland, New Zealand Spirometry for those with smoking and dust exposures Risk

More information

Normal ranges of left ventricular global longitudinal strain: A meta-analysis of 2484 subjects

Normal ranges of left ventricular global longitudinal strain: A meta-analysis of 2484 subjects Normal ranges of left ventricular global longitudinal strain: A meta-analysis of 2484 subjects Teerapat Yingchoncharoen MD. Shikar Agarwal MD. MPH. Thomas H. Marwick MBBS. Ph.D. MPH. Cleveland Clinic Foundation

More information

Imaging Markers of Brain Network Dysfunction in Multiple Sclerosis

Imaging Markers of Brain Network Dysfunction in Multiple Sclerosis Faculty of Medicine & Health Sciences School of Medicine Radiological Sciences Research Group The University of Nottinham University Park Nottingham NG7 2RD t: +44 (0)115 823 0018 f: +44 (0)115 823 0004

More information

DEVELOPMENT OF AN IMAGING SYSTEM FOR THE CHARACTERIZATION OF THE THORACIC AORTA.

DEVELOPMENT OF AN IMAGING SYSTEM FOR THE CHARACTERIZATION OF THE THORACIC AORTA. DEVELOPMENT OF AN IMAGING SYSTEM FOR THE CHARACTERIZATION OF THE THORACIC AORTA. Juan Antonio Martínez Mera Centro Singular de Investigación en Tecnoloxías da Información Universidade de Santiago de Compostela

More information

MEDICAL BREAKTHROUGHS RESEARCH SUMMARY TOPIC: MAMMOGRAM FOR THE HEART: CORONARY CALCIUM SCORE REPORT: MB #4014

MEDICAL BREAKTHROUGHS RESEARCH SUMMARY TOPIC: MAMMOGRAM FOR THE HEART: CORONARY CALCIUM SCORE REPORT: MB #4014 MEDICAL BREAKTHROUGHS RESEARCH SUMMARY TOPIC: MAMMOGRAM FOR THE HEART: CORONARY CALCIUM SCORE REPORT: MB #4014 BACKGROUND: Heart disease is a term that can refer to several types of heart conditions. Coronary

More information

U.K. Familial Ovarian Cancer Screening Study (UK FOCSS) Phase 2 Patient Information Sheet

U.K. Familial Ovarian Cancer Screening Study (UK FOCSS) Phase 2 Patient Information Sheet U.K. Familial Ovarian Cancer Screening Study (UK FOCSS) Phase 2 Patient Information Sheet 1. Invitation You are being invited to take part in a research study. Before you decide it is important for you

More information

Summary Evaluation of the Medicare Lifestyle Modification Program Demonstration and the Medicare Cardiac Rehabilitation Benefit

Summary Evaluation of the Medicare Lifestyle Modification Program Demonstration and the Medicare Cardiac Rehabilitation Benefit The Centers for Medicare & Medicaid Services' Office of Research, Development, and Information (ORDI) strives to make information available to all. Nevertheless, portions of our files including charts,

More information

Atrial Fibrillation An update on diagnosis and management

Atrial Fibrillation An update on diagnosis and management Dr Arvind Vasudeva Consultant Cardiologist Atrial Fibrillation An update on diagnosis and management Atrial fibrillation (AF) remains the commonest disturbance of cardiac rhythm seen in clinical practice.

More information

Gene Therapy. The use of DNA as a drug. Edited by Gavin Brooks. BPharm, PhD, MRPharmS (PP) Pharmaceutical Press

Gene Therapy. The use of DNA as a drug. Edited by Gavin Brooks. BPharm, PhD, MRPharmS (PP) Pharmaceutical Press Gene Therapy The use of DNA as a drug Edited by Gavin Brooks BPharm, PhD, MRPharmS (PP) Pharmaceutical Press Contents Preface xiii Acknowledgements xv About the editor xvi Contributors xvii An introduction

More information