7 th WACBE World Congress on Bioengineering

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1 世 界 華 人 生 物 醫 學 工 程 協 會 World Association for Chinese Biomedical Engineers 7 th WACBE World Congress on Bioengineering 6 th - 8 th July 205 Singapore Organised & Hosted by Department of Biomedical Engineering Faculty of Engineering

2 世 界 華 人 生 物 醫 學 工 程 協 會 World Association for Chinese Biomedical Engineers Organised & Hosted by Department of Biomedical Engineering Faculty of Engineering Endorsed by Sponsor Supporters FOREWORD On behalf of the Organizing Committee of the WACBE World Congress on Bioengineering 205 (WACBE 205), we would like to warmly welcome you to this meeting. This congress is part of a series that began in 2002 and we had six meetings thus far. This year s meeting is jointly organized by the Department of Biomedical Engineering of the National University of Singapore (NUS) and the Biomedical Engineering Society (Singapore) (BES). This congress is also endorsed by the International Federation for Medical and Biological Engineering (IFMBE). We are glad to report that we have more than 250 participants from 7 countries. In this congress, we have received close to 300 abstracts with 50 being keynote/invited presentations. The rest of the contributed abstracts were peer-reviewed, with 24 accepted for oral and 99 accepted for poster presentations. Out of these accepted abstracts, we received 55 final papers submitted for the proceedings, with 2 being invited papers, 25 oral presentation papers and 28 Poster papers. We are very honoured to have Prof Kam Leong as the inaugural Savio Woo Distinguished Lecturer, as well as other very prominent speakers as our Plenary and Keynote Speakers. Each of these speakers is an authority in their field of research and we are grateful that they are able to participate in this congress. We do know that the success of a congress lies in the participation of the delegates and the quality of papers presented. Nevertheless, we also know that this will not be possible without the help and effort put in by the volunteers, reviewers, as well as the members of the Organizing Committee, Scientific Committee and the International Advisory Committee. Their dedicated contributions to this meeting are very much acknowledged and appreciated. We would also like to sincerely thank our sponsors, supporters and exhibitors for contributing to the success of this congress. Finally, we would like to thank the staff of INMEET CMS Pte Ltd who has ensured the smooth running of the congress. Finally, to all our delegates, I hope this WACBE 205 meeting will not only be one where excellent scientific ideas are exchanged and shared, but also friendships are renewed and new friends made. Do enjoy the congress as well as the sights and sounds of Singapore! Best wishes Prof James Goh Chairman Prof Chwee Teck LIM Scientific Program Chair WACBE 205 Organizing Committee 7th WACBE World Congress on Bioengineering

3 Table of Contents Foreword Committees 3-4 Themes & Topics 5 Speakers 6 General Information 8 Programme App 9 Venue Floorplan & Activity Locator 0- Programme Monday, 6 July Tuesday, 7 July Wednesday 8 July List of Posters 36 Organising Committee Chairman: GOH James, Vice Chair: TOH Siew Lok, Secretary: LIM Sierin, Nanyang Technological University, Singapore Treasurer: BUIST Martin, International Advisory Committee Chair: CHEW Yong Tian, Scientific Programme Chair: LIM Chwee Teck, Scientific Programme Co-Chair: ZHANG Yong, International Advisory Committee Members: AN Kai-Nan, Mayo Clinic, USA CHENG Cheng-Kung, National Yang Ming University, Taiwan CHENG Dong, Penn State University, USA CHIEN Shu, University of California, San Diego, USA FAN Yubo, Beihang University, China GUO Edward, Columbia University, USA HSING I-Ming, The Hong Kong University of Science and Technology, Hong Kong JI Baohua, Beijing Institute of Technology, China KING Albert, Wayne State University, USA LEE Abraham, University of California, Irvine, USA LEE Peter Vee Sin, The University of Melboume, Australia LEONG Kam W., Columbia University, USA LI Guoan, Massachusetts General Hospital / Harvard Medical School, USA LI Zong-Ming, Cleveland Clinic, USA LIN Feng-Huei, National Taiwan University, Taiwan LIN Kang-Ping, Chung Yuan Christian University, Taiwan LU Helen, Columbia University, USA LU William, The University of Hong Kong, Hong Kong MAK Arthur FT, The Chinese University of Hong Kong, Hong Kong NING Gangmin, Zhejiang University, China OUYANG Hongwei, Zhejiang University, China PHEE Louis, Nanyang Technological University, Singapore SU Fong-Chin, National Cheng Kung University, Taiwan SUNG Hsing-Wen, National Tsing-Hua University, Taiwan TEOH Swee Hin, Nanyang Technological University, Singapore WANG Jawlin, National Taiwan University, Taiwan WU Benjamin, University of California, Los Angeles, USA YANG Changhuei, California Institute of Technology, USA ZHANG Fan, Fudan University, China ZHANG Ming, The Hong Kong Polytechnic University, Hong Kong Committees 7th WACBE World Congress on Bioengineering 3

4 Scientific Program Committee Themes and Topics Chair: LIM Chwee Teck, Co-Chair: ZHANG Yong, Members: CHEN Chia Hung, CHEN Nanguang, CORRIAS Alberto, HUANG Zhiwei, KAH Chen Yong James, KANCHANAWONG Pakorn Tony, LI Jun, LEO Hwa Liang, MUSIB Mrinal Kanti, REN Hongliang, TAN Kian Lee, TOH Siew Lok, YEN Shih Cheng, YIM Evelyn, YU Haoyong, Bioimaging and Biosignals Bioelectronics Biosignal Processing Image Guided Intervention Medical Imaging Optical Imaging Biophotonics Biomaterials and Tissue Engineering Biological Materials Biopolymers Bioceramics Biometals Nanobiomaterials Composite Materials Biomaterial-tissue Interaction Implant Materials Regenerative Medicine Biomechanics and Computational Bioengineering Biomimetics Mechanobiology Molecular Biomechanics Cell Mechanics Tissue Mechanics Cardiovascular Mechanics Organ Mechanics Musculoskeletal Mechanics Orthopaedics Sports Mechanics Insect and Animal Biomechanics Computational Mechanics Biomedical and Micro/Nano-Devices Biosensors BioMEMS Microarrays Organ-on-Chip Lab-on-a-Chip Micro/Nanofluidics Micro/Nanofabrication Micro-Total Analysis Systems Diagnostic Devices Implantable Devices Surgical Tools Interventional Devices Biomedical Device Innovation Nanomedicine Nanomaterial Design and Synthesis Nanotoxicology Diagnosis and Imaging Controlled/Targeted Drug Delivery Controlled Gene Delivery Therapeutic Applications Theranostics Biomedical Robotics and Surgical Technology Bio- and Medical Robotics Bioinstrumentation and Control Soft Robotics Computer Aided Surgery Healthcare Information Sensing and Analytics Wireless Sensors E-Health System Neural and Rehabilitation Engineering Clinical and Translational Neuroengineering Cognitive Engineering Neurotechnology Neurotherapeutics Assisted Technologies Rehabilitation Special Topics Bioet hics Biomedical Engineering Education Manuscript Writing Medical Device Regulation 4 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 5

5 SPEAKERS Savio Woo Distinguished Lecture Speaker Plenary Speakers Kam W. LEONG Samuel Y. Sheng Professor Columbia University, USA Bioengineering of Direct Cellular Reprogramming Monday, 6 July 205 9:45 am - 0:45 am Auditorium Hsueh-Chia CHANG Bayer Professor of Engineering Director, Center for Microfluidics and Medical Diagnostics Department of Chemical and Biomolecular Engineering University of Notre Dame, USA A BioChip Platform for Point-of-Care Diagnostic Devices Monday, 6 July 205 :5 am - 2:00 pm Auditorium Michael SHEETZ Director, Mechanobiology Institute Distinguished Professor of the Department of Biological Sciences, National University of Singapore & Professor of the Department of Biological Sciences, Columbia University, USA Rigidity Sensing Through Pinching Sarcomeres Tuesday, 7 July 205 9:30 am - 0:5 am Auditorium Guang-Zhong YANG Director and Co-founder of the Hamlyn Centre for Robotic Surgery Deputy Chairman of the Institute of Global Health Innovation, Imperial College, UK Robotic Surgery Current State-of-the-Art and Emerging Trends Wednesday, 8 July 205 9:30 am - 0:5 am Auditorium Keynote Speakers Peter SO Professor of Mechanical Engineering and Biological Engineering, Massachusetts Institute of Technology, USA Advances in Quantitative Phase Microscopy for Cell Mechanics Measurements Monday, 6 July 205 :30 pm - 2:00 pm Auditorium Nitish THAKOR Director SINAPSE, Frontiers of Neurotechnology Monday, 6 July 205 4:5 pm - 4:45 pm Auditorium Dong SUN Chair Professor of Biomedical Engineering, City University of Hong Kong, Hong Kong Single Cell Fusion with Optical Tweezers Manipulation System Tuesday, 7 July 205 0:45 am - :5 am Auditorium Yubo FAN Professor of Biological and Medical Engineering, Beihang University, China Computational Methodology in Biomechanics Tuesday, 7 July 205 2:30 pm - 3:00 pm Auditorium Kirk SHUNG Dean s Professor in Biomedical Engineering, University of Southern California, USA High Frequency Ultrasound and Its Biomedical Applications Wednesday, 8 July 205 0:45 am - :5 am Auditorium Guy GENIN Professor, Washington University in St. Louis, USA Reattaching Tendon to Bone Wednesday, 8 July 205 2:00 pm to 2:30 pm Auditorium 6 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 7

6 General Information Programme App Conference Venue Town Plaza, University Town (UTown) National University of Singapore Registration Desk Opening Hours Level, Town Plaza, UTown Foyer of Auditorium Monday, 6 July 205 8:30am 4:30pm Tuesday, 7 July 205 9:00am 3:00pm Wednesday, 8 July 205 9:00am 2:00pm Conference Banquet (Ticketed event) Date : Tuesday, 7 July 205 Time : 6:30pm 9:30pm Venue : NUS Kent Ridge Guild House Menu : Chinese menu (no pork, no lard) / Chinese Vegetarian Dress Code : Smart Casual Ticket price : S$60 per ticket Participants who have purchased tickets will receive their tickets in the conference kit issued to them onsite. Complimentary bus service from the conference venue to the banquet venue will be provided. Please check with the registration counter for bus pick up schedule. Limited tickets are available for sale onsite, on a first-come-first-served basis. Ticket sale closes at 2 pm on Monday, 6 July 205. (Note: Only cash payment will be accepted for onsite purchase). Badges & Security All participants will receive their badges upon registration. It is mandatory that participants wear their badges at all times when at the conference venue. Language The official language of the conference is English. No translation will be provided Liability The Organising Committee is not liable for personal accidents or loss/damage of private properties of registered participants during the conference. Disclaimer The Organising Committee reserves the right to make any necessary changes in the programme. Whilst every attempt is made to ensure that all aspects of the conference will be carried out as scheduled, the Organising Committee is not responsible for any personal expenses incurred or any loss suffered by any participant or his/her accompanying guest in connection with changes in the conference schedule. The conference programme and abstracts can be accessed via the Conference4Me App. Download the app to browse the complete programme directly from your phone or tablet and create your very own agenda on the fly. The app is available for Android, ios, Windows Phone and Kindle Fire devices. 8 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 9

7 Venue Floor Plan & Activity Locator Level, Town Plaza, U-Town Level 2, Town Plaza, U-Town Activity Location Opening Session Level, Auditorium Plenary / Keynote Lectures Level, Auditorium Parallel Sessions Level, Auditorium & (Invited and Oral Presentations) Level 2, Seminar Rooms 5&6; 7&8; 2 Poster Session Level 2, Foyer Closing Session Level, Auditorium Tea breaks Level 2, Balcony Registration Desk Level, Auditorium Foyer Secretariat Room Level 2, Seminar Room 4 0 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering

8 Programme Monday, 6 July 205 Welcome Address 9:30am 9:45am Auditorium Savio Woo Distinguished Lecture 9:45am - 0:45am Auditorium Session Chair: James Goh Bioengineering of Direct Cellular Reprogramming Kam Leong Columbia University, USA Morning Tea Break 0:45 am - :5am Plenary Lecture :5am - 2:00pm Auditorium Session Chair: Chwee Teck Lim A BioChip Platform for Point-of-Care Diagnostic Devices Hsueh-Chia Chang University of Notre Dame, USA Lunch & Poster Session 2:00pm - :30pm Keynote :30pm - 2:00pm Auditorium Session Chair: Zhiwei Huang Advances in Quantitative Phase Microscopy for Cell Mechanics Measurements Peter So Massachusetts Institute of Technology, USA Short Break 2:00 pm - 2:5pm Session A - Cell Mechanics & Biomimetics Monday, 06 July 205 2:5pm - 3:45pm Auditorium Session Chairs: Po-Yu Chen; Shyh-Hau Wang Underwater Adhesion of Aquatic Animals: Hierarchical Structure, Attachment Mechanisms and Biomimetics Yung-Chieh Chuang, Guan-Lin Liu,2, Po-Yu Chen National Tsing Hua University, Taiwan; 2 Institute of Nuclear Energy Research, Taiwan Cytotoxicity of Ag Nanoparticles to Cytoskeleton and Mechanical Behavior of Red Blood Cells Shou-Yi Chang, Ruei-Yi Tsai, Yen-Chung Chen, Yu-Ying Shie, Ying-Ting Wang National Chung Hsing University, Taiwan The Assessment of Toxicity of Hydroxyapatite (HAP) and Boron Nitride (BN) Nanoparticle using Atomic Forced Microscopy Mohammad Alim Iftekhar Rasel, Trung Dung Nguyen, Yuantong Gu Queensland University of Technology, Australia Effect of High Glucose on the Physical Properties of Cellular Membrane Da-Ming Huang, Shyh-Hau Wang National Cheng Kung University, Taiwan Role of Geometrical Cues on Cancer Cell Growth Parthiv Kant Chaudhuri, Boon C Low,2, Chwee Teck Lim,3 Mechanobiology Institute, ; 2 Cell Signaling and Developmental Biology Laboratory, Department of Biological Sciences, ; 3 Department of Biomedical Engineering, Session B - Biomedical Imaging I Monday, 06 July 205 2:5pm - 3:45pm Seminar Rm 2 Session Chairs: Kang-Ping Lin; Feminna Sheeba Structure Analysis of Tumor Vascular Images on Gene-Mice Kang-Ping Lin,3, Wen-Chen Lin,3, Cheng-Lun Tsai 2,3 Department of Electrical Engineering, Chung Yuan Christian University, Taiwan; 2 Department of Biomedical Engineering, Chung Yuan Christian University, Taiwan; 3 Technology Translation Center for Medical Device, Chung Yuan Christian University, Taiwan RBX based Severity Classification of Rosacea Po-Han Huang, Chih-Yu Wang 2, Shu-Chen Chang 3 Aesthetics Center, Kaohsiung Chang Gung Memorial Hospital, Taiwan; 2 Department of Biomedical Engineering, I-Shou University, Taiwan; 3 Department of Hospitality Management, Tajen University, Taiwan 2 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 3

9 Convex Hull Based Detection of Clumped Red Blood Cells in Peripheral Blood Smear Images Feminna Sheeba, Robinson Thamburaj, Joy John Mammen 2, Mohan Kumar S., Vansant Rangslang Madras Christian College, India; 2 Christian Medical College, India Morphology Based Detection of Abnormal Red Blood Cells in Peripheral Blood Smear Images Kulasekaran S., Feminna Sheeba 2, Joy John Mammen 2, Saivigneshu B. 2, Mohan Kumar S. 2 Healthcare Technology Innovation Centre, India; 2 Madras Christian College, India Novel Method for 3D Reconstruction of the Chick Embryo Cardiovascular Anatomy from Non-invasive Ultrasound Scans for Longitudinal Studies Germaine Xin Yi Tan, Muhammad Jamil, Nicole Gui Zhen Tee 2, Liang Zhong 2,3, Choon Hwai Yap Department of Biomedical Engineering, ; 2 National Heart Research Institute of Singapore, National Heart Centre Singapore, Singapore; 3 Duke-NUS Graduate Medical School, Monitoring Hemodynamic Changes in Brain Infarct Area of Rats Using Diffuse Optical Imaging Kang-Yu Chu, Chun-Wei Wu, Jia-Jin Jason Chen National Cheng Kung University, Taiwan Session C - Stem Cell & Tissue Engineering Monday, 06 July 205 2:5pm - 3:45pm Seminar Rm 5&6 Session Chaird: Barbara Chan; Yi-Chin Toh Approaches to Engineering Cartilage with Normal Structure and Function Eng Hin Lee Multiphoton-based Free Writing of 3D Protein Microstructures and Micropatterns with Sub-Micron Features A Platform for Stem Cell Niche Studies Barbara Chan, JN Ma, JY Xu, CW Li, MH Tong, N Huang The University of Hong Kong, Hong Kong S.A.R. (China) Modulation of Integrin and E-Cadherin-Mediated Adhesions to Spatially Control Heterogeneity in Human Pluripotent Stem Cell Differentiation Yi-Chin Toh Characterisation of the Interaction between Osteoarthritic Articular Cartilage and Implant Materials Niloofar Ajdari, Ulrich Hansen, Daniele Dini Imperial College London, UK The Promotion of Cardiomyogenic Differentiation of Porcine Bone Marrow-Derived Mesenchymal Stem Cells thru 5-Azacytidine and Ascorbic Acid Exposure Maria Christine Tankeh Asuncion, James Cho-Hong Goh,2, Siew-Lok Toh,3 Biomedical Engineering, ; 2 Orthopaedic Surgery, National University of Singapore, Singapore; 3 Mechanical Engineering, Induced Pluripotent Stem Cell Differentiation Under Constant Shear Stress Nur Khatijah Binti Mohd Zin, Katsuhisa Sakaguchi, Y. Haraguchi 2, T. Yagi, K. Matsuura 2, Tatsuya Shimizu 2, Mitsuo Umezu,2 Waseda University, Japan; 2 Tokyo Women Medical University, Japan Session D - Biomicrofluidics I Monday, 06 July 205 2:5pm - 3:45pm Seminar Rm 7&8 Session Chairs: Feng Xu; Bee Luan Khoo Engineering of 3D Cell Microenvironment and its Biomedical Applications Feng Xu,2 The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi an Jiaotong University, China; 2 Bioinspired Engineering and Biomechanics Center (BEBC), Xi an Jiaotong University, China Microfluidic Pipette Array for Cellular Mechanophenotyping and Mechanotransduction Allen Liu University of Michigan, USA Multiplexed Spiral Inertial Microfluidics for the High-Throughput and Label-Free Enrichment of Viable Circulating Tumor Cells Bee Luan Khoo, Majid Ebrahimi Warkiani 5, Han Jongyoon 2,4, Lim Chwee Teck,2,3 Mechanobiology Institute - NUS (NGS), Singapore; 2 BioSystems and Micromechanics (BioSyM) IRG, Singapore-MIT Alliance for Research and Technology (SMART) Centre, Singapore; 3 Department of Biomedical engineering, ; 4 Department of Electrical Engineering and Computer Science, Department of Biological Engineering, Massachusetts Institute of Technology, USA; 5 School of Mechanical and Manufacturing Engineering, Australian Centre for NanoMedicine, University of New South Wales, Australia Salmonella Detection on Microfluidic CD using Loop Mediated Isothermal Amplification Abkar Ahmed Sayad,2, fatimah Ibrahim,2, Mas S. Mohktar,2, Kwai Lin Thong 2,3 Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Malaysia; 2 Centre for Innovation in Medical Engineering (CIME), Faculty of Engineering, University of Malaya, Malaysia; 3 Microbiology Unit, Institute of Biological Sciences, Faculty of Science, University of Malaya, Malaysia Protease Assay for Single Cancer Cells through Jetting Droplet Microfluidics Tengyang Jing,2, Ramesh Ramji, Majid Ebrahimi Warkiani 2,3, Jongyoon Han,4, Chwee Teck Lim,2,5, Chia-Hung Chen,2,6 ; 2 Singapore-MIT Alliance for Research and Technology Centre, Singapore; 3 University of New South Wales, Australia; 4 Massachusetts Institute of Technology, USA; 5 Mechanobiology Institute, Singapore; 6 Singapore Institute for Neurotechnology, Singapore Afternoon Tea Break 3:45 pm - 4:5pm 4 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 5

10 Keynote 2 Monday, 06 July 205 4:5pm - 4:45pm Auditorium Session Chair: Haoyong Yu Frontiers of Neurotechnology Nitish Thakor SINAPSE, Short Break 4:45 pm - 5:00pm Session 2A - Tissue Mechanics Monday, 06 July 205 5:00pm - 6:30pm Auditorium Session Chair: Zong-Ming Li; Peter Vee Sin Lee Biomechanics of the Carpal Tunnel and Transverse Carpal Ligament Zong-Ming Li Cleveland Clinic, USA A Hierarchical Approach to Investigate Cartilage and Subchondral Bone Responses under Impact Load Peter Vee Sin Lee University of Melbourne, Australia Surface Wrinkling and Morphological Evolution of Soft Biological Tissues Xi-Qiao Feng Tsinghua University, China A Method of Measuring Corneal Young s Modulus Chun-Ju Huang National Taiwan University, Taiwan Mechanical Properties of Human Placenta in Normal Pregnancies and During Intrauterine Growth Restriction Jeanette Shifen Lau, Shier Nee Saw 2, Martin Lindsay Buist2, Choon Hwai Yap 2 Department of Mechanical Engineering, ; 2 Department of Biomedical Engineering, A Multi-scale Model of Gastrointestinal Electromechanics Nicholas Cheng, Alberto Corrias, Martin Buist Session 2B - Biomedical Imaging II Monday, 06 July 205 5:00pm - 6:30pm Seminar Rm 2 Session Chairs: Hanry Yu; Zhiwei Huang Spatial and Temporal Morphological Markers for Liver Regeneration and Chronic Liver Diseases Hanry Yu,2,3 ; 2 Institute of Bioengineering and Nanotechnology, A*STAR, Singapore; 3 Mechanobiology Institute, Singapore Detection of Overlapping Tuberculosis Bacilli in Sputum Smear Images Feminna Sheeba, Robinson Thamburaj, Joy John Mammen 2, Nitish R., Karthick S. Madras Christian College, India; 2 Christian Medical College, India Functional Mapping of Enamel Caries Using Hyperspectral Stimulated Raman Scattering Imaging Zi Wang, Wei Zheng, Chin-Ying {Stephen} Hsu, Zhiwei Huang Development of Low Cost Set Up Microscopic Skin Imaging using Structured Light Projection Naila Zahra, Suprijanto Suprijanto, Endang Juliastuti Institut Teknologi Bandung, Indonesia In-vivo 3D Strain Mapping of Optic Nerve Head Tissues in Humans Meghna Rakesh Beotra, Amanjeet Sandhu 3, Cheuk Wang Chung, Nicholas Strouthidis 3,2, Michael JA Girard,2 Department of Biomedical Engineering, ; 2 Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; 3 NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK Session 2C - Nanomedicine Monday, 06 July 205 5:00pm - 6:30pm Seminar Rm 5&6 Session Chairs: Jiashu Sun; Yih-Chih Hsu Phenotypic Personalized Medicine: Integrating Nanomedicine with Engineering Optimization Platforms to Transform Combination Therapy Dean Ho Department of Bioengineering, UCLA, USA Microfluidic Synthesis of Rigid Nanovesicles for Hydrophilic Reagents Delivery Jiashu Sun National Center for Nanoscience and Technology, China 6 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 7

11 Controlled Release of 5-FU from PEG-based Nanoparticle Jen-Ming Yang Chang Gung University, Taiwan Combination Therapy of Nanoparticle Targeted Delivery of HIFa sirna and Photodynamic Therapy as a Potential Treatment Strategy for Oral Cancers Wei-Hua Chen, Rumwald Leo G. Lecaros 2, Yu-Cheng Tseng 3, Leaf Huang 3,4,5, Yih-Chih Hsu 4,5,6 Graduate Program of Nanotechnology, Chung Yuan Christian University, Taiwan; 2 Graduate Program of Bioscience Technology, Chung Yuan Christian University,Taiwan; 3 Division of Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, USA; 4 Department of Bioscience Technology, Chung Yuan Christian University, Taiwan; 5 Center of Biomedical Technology, Chung Yuan Christian University, Taiwan; 6 Center for Nanotechnology, Chung Yuan Christian University, Taiwan Immuno-Suppressive Agent found by Chip-Based Protein Immobilization Screening Method Hueih-Min Chen National Applied Research Laboratories, Taiwan Reduction of Amyloid Beta Plaques by Opening the Blood Brain Barrier using Focused Ultrasound and Delivering Antibodies in a Rabbit Model Fed with High Cholesterol Diet Christakis Damianou Cyprus University of Technology, Cyprus Session 2D - Neural & Rehabilitation Engineering Monday, 06 July 205 5:00pm - 6:30pm Seminar Rm 7&8 Session Chairs: Shing-Hong Liu; Zengyong Li Our Trial on Biomedical Engineering Research and Education System Related to Medical Regulatory Science Mitsuo Umezu Waseda University, Japan Analysis of Electroencephalogram for Element School Students with and without Dyslexia Shing-Hong Liu, Min-Ching Hsu, Hui-Chin Lin, Jia-Jung Wang 2 Chaoyang University of Technology, Taiwan; 2 I-Shou University, Taiwan Development of a Multi-Channel Electrocorticography Seizure Detection Method for Presurgical Evaluation Sheng-Fu Liang, Yu-Hsuan Shih, Yi-Lin Chen 2, Yue-Loong Hsin 3 National Cheng Kung University, Taiwan; 2 Biomedical Electronics Translational Research Center, Taiwan; 3 Chung Shan Medical University, Taiwan Altered Resting State Functional Connectivity in Elderly Subjects with Cerebral Infarction as Revealed By NIRS Method Qitao Tan, Yi Wang 2, Manyu Zhang, Qing Xin 3, Bitian Wang, Zengyong Li Shandong University, China; 2 Ji nan Central Hospital, China; 3 Hospital of Shandong University, China Application of Cortical Optogenetic Stimulation of Animal Model for Modulating Motor Plasticity Cho-Han Hsieh, Chun-Wei Wu, Jia-Jin Jason Chen National Cheng Kung University, Taiwan The Influence of Cutaneous Stimulation on EMG Activities of Lower Extremity Hsin-Hsuan Liu, Yuan-Chun Chiu, Chun-Yu Yeh, Hsiao-Yun Chang Chung Shan Medical University, Taiwan Welcome Reception 6:30pm - 8:30pm Programme Tuesday, 7 July 205 Plenary Lecture 2 Tuesday, 07 July 205 9:30am - 0:5am Auditorium Session Chair: Hanry Yu Rigidity Sensing Through Pinching Sarcomeres Michael Sheetz Mechanobiology Institute of Singapore, Morning Tea Break 0:5 am - 0:45am Keynote 3 Tuesday, 07 July 205 0:45am - :5am Auditorium Session Chair: Desmond Y.R. Chong Single Cell Fusion with Optical Tweezers Manipulation System Shuxun Chen, Ran Wang, C Li 2, Jinping Cheng 3, S. H. Cheng, R. A. Li 2, Kwan Man2, Dong Sun City University of Hong Kong; 2 The University of Hong Kong; 3 The Hong Kong University of Science and Technology, Hong Kong, China (S.A.R) Short Break :5 am - :30am 8 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 9

12 Session 3A - Gait Mechanics Tuesday, 07 July 205 :30am - :00pm Auditorium Session Chairs: Gangmin Ning; Yaohui, Kelvin Chua Adaptive Reaction Time Strategy in Obstacle Crossing Test Gangmin Ning, Guifeng Jia, Lingyan Gu, Shengyu Zhang, Xiaoqing Jin 2, Yidan Chen 2, Lijian Qiu Dept. of Biomedical Engineering, Zhejiang University, China; 2 Zhejiang Hospital, China Kinematic Investigation on the Mimicry Ability within Healthy Subjects with Video-Based Rehabilitation Fan-Zhe Low, Hong Kai Yap 2, Raye Chen-Hua Yeow,3 Department of Biomedical Engineering, ; 2 NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore; 3 Singapore Institute for Neurotechnology - Advanced Robotics Center (SINAPSE-ARC), An Investigation of Muscle Contributions in Crouch Gait Patients with Different Severities in Stance and Swing Phases Chow Khuen Chan, Chen Hua Yeow Profiling of Pedestrian Crossings across Five Singapore Districts YaoHui Kelvin Chua, Pui Wah Kong Physical Education and Sports Science Academic Group, National Institute of Education, Nanyang Technological University, Singapore A Biomechanical Study to Compare the Differences between Different Styles of School Bag Carrying Luis Carlos Hernandez Barraza, Yeow Chen-Hua,2 ; 2 SINAPSE-Advanced Robotic Center, Singapore A Wearable Sensors System for Racehorses Jin Huat Low, Vanessa Wei Lin Mak, Chen-Hua Yeow The Influence of Bilateral Sagittal Split Ramus Osteotomy on the Stress Distributions in Temporomandibular Joint Yuanli Zhang, Xianchao Xu, Yubo Fan 2, Zhan Liu Provincial Key Lab for Biomechanical Engineering, Sichuan University, China; 2 Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beihang University, China Session 3B - Biomedical Imaging III Tuesday, 07 July 205 :30am - :00pm Seminar Rm 2 Session Chairs: Hui Ma; Cheuk Wang Chung Polarization Microscopy for Diagnostic Applications Hui Ma Tsinghua University, China Retinal Vasculature Segmentation in Smartphone Ophthalmoscope Images Saranya Devi Subramaniam, Ramachandran K.I, Ashish Sharma 2 Amrita Vishwa Vidyapeetham, India; 2 Lotus Eye Care Hospital, Coimbatore,India 3D Laparoscopic Conversion Technology by using Tracking of Interest Points Min-Liang Wang Chang Bing Show Chwan Memorial Hospital, Taiwan Mean Flow Umbilical Doppler Indices Perform Better than Pulsatility Indices in Determining Small for Gestational Age Pregnancies Shier Nee Saw, Citra Nurfarah Zaini Mattar 2, Seow Heong Yeo 3, Shu-E Soh 4,5, Yap-Seng Chong 2,7, Peter David Gluckman 7,8, Keith Godfrey 9, Seang Mei Saw 5,6, Arijit Biswas 2, Choon Hwai Yap Department of Biomedical Engineering, ; 2 Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, National University Health Systems, Singapore; 3 Department of Maternal Fetal Medicine, KK Women s and Children s Hospital, Singapore; 4 Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; 5 Saw Swee Hock School of Public Health, National University of Singapore, Singapore; 6 Singapore Eye Research Institute, Singapore; 7 Singapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore; 8 Liggins Institute, University of Auckland, New Zealand; 9 MRC Lifecourse Epidemiology Unit, NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, UK Medical Image Encryption using Block-based Scrambling and Discrete Wavelet Transform Kulasekaran S., Feminna Sheeba 2, Saivigneshu B. 2, Dayalan C. 2, Cyril Rex P. 2 Healthcare Technology Innovation Centre, India; 2 Madras Christian College, India High-resolution Quantitative Mapping of Microstructural Organisation in Porcine Peripapillary Sclera and Lamina Cribrosa Cheuk Wang Chung, Zhi Yun Chin, Meghna Rakesh Beotra, Liang Zhang,2, Michael JA Girard,3 Department of Biomedical Engineering, ; 2 NUS Graduate School for Integrative Sciences and Engineering, ; 3 Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 20 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 2

13 Session 3C - Biomaterials I Tuesday, 07 July 205 :30am - :00pm Seminar Rm 5&6 Session Chairs: Min Wang; Hui-Fen Wu Bioceramics and Biomedical Nanocomposites for Tissue Replacement and Regeneration Min Wang Department of Mechanical Engineering and Medical Engineering Programme, The University of Hong Kong, Pokfulam Road, Hong Kong Fabrication of Peptide-Modified Zwitterionic Porous Hydrogels for Vascular Engineering Jiashing Yu, Chih-Yeh Lin Dept of Chemical Engineering, National Taiwan University, Taiwan Nanomaterial Techniques Applied on Pathogenic Bacteria Analysis Hui-Fen Wu National Sun Yat-Sen University, Taiwan In Vivo Osteogenesis of Gelatin/Thai Silk Fibroin and Gelatin/ Hydroxyapatite/Thai Silk Fibroin Scaffolds Tonporn Lamlerd, Kumpanart Soontornvipart 2, Sorada Kanokpanont 3, Sawang Kesdangsakonwut 4, Siriporn Damrongsakkul 3 Biomedical Engineering Program, Faculty of Engineering, Chulalongkorn University, Thailand; 2 Department of Surgery, Faculty of Veterinary Science, Chulalongkorn University, Thailand; 3 Department of Chemical Engineering, Faculty of Engineering, Chulalongkorn University, Thailand; 4 Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Thailand Viscoelastic Effects of Silicone Gels on Cellular Traction Force Measurements Kenry, Man Chun Leong, Mui Hoon Nai, Fook Chiong Cheong, Chwee Teck Lim Study on Mechanical Properties of EVA Blended with Graphene Yanbing Liang, Yuhui Cai, Haisheng Su, Gang Zhou, Lizhen Wang, Yubo Fan,2 Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China.; 2 National Research Center for Rehabilitation Technical Aids, Beijing, China Session 3D - Biomedical Robotics and Surgical Technology Tuesday, 07 July 205 :30am - :00pm Seminar Rm 7&8 Session Chairs: Pheng Ann Heng; Hongliang Ren Virtual Reality Based Surgical Simulation Pheng Ann Heng The Chinese University of Hong Kong, Hong Kong S.A.R. (China) Exoskeleton Hand Robotic Training Device Using Brainwave and Muscle Activities Raymond Kai-yu Tong,2, Evan A. Susanto,2, Newmen S.K. Ho 2, Peter M.K. Pang 2 The Chinese University of Hong Kong, Hong Kong S.A.R. (China); 2 The Polytechnic University of Hong Kong, Hong Kong S.A.R. (China) Indirect Distal End Force Sensing for a Tendon Driven Flexible Transoral Surgical Manipulator Wenjun Xu, Hongliang Ren Three Dimensional Panorama Visualization for Endoscopic Video Atul Kumar, Yen-Yu Wang,3, Kai-Che Liu, Wan-Chi Hung, Shih-Wei Huang, Wen-Nung Lie 2, Ching-Chun Huang 2 Chang Bing Show Chwan Memorial Hospital, Taiwan; 2 National Chung Cheng University, Taiwan; 3 National Changhua University of Education, Taiwan Finite Element Analysis and Design Optimization of Soft Pneumatic Actuators for Hand Robotic Rehabilitation Applications Hong Kai Yap,2, Jeong Hoon Lim 3, James Cho Hong Goh, Raye Chen-Hua Yeow,4 Department of Biomedical Engineering, National University of Singapore; 2 NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore; 3 Department of Medicine, National University Hospital, Yong Loo Lin School of Medicine, National University of Singapore; 4 Singapore Institute for Neurotechnology - Advanced Robotics Center (SINAPSE-ARC), Bioinspired Tactile Sensor and Spiking Trains for Light Touch Perception Zhengkun Yi, Yilei Zhang Nanyang Technological University, Singapore Lunch & Poster :00 pm - 2:30pm Keynote 4 Tuesday, 07 July 205 2:30pm - 3:00pm Auditorium Session Chair: Martin Buist Computational Methodology in Biomechanics Yubo Fan Beihang University, China Short Break 3:00pm - 3:5pm 22 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 23

14 Session 4A - Musculoskeletal Mechanics Tuesday, 07 July 205 3:5pm - 4:45pm Auditorium Session Chairs: Fong-Chin Su, Siew Lok Toh The Coordination of Digits Forces during Natural Five-Digit Precision Grasping Fong-Chin Su, Po-Tsun Chen, Chien-Ju Lin, Hsiao-Feng Chieh, Li-Chieh Kuo, I-Ming Jou National Cheng Kung University, Taiwan Computational Contact Biomechanics for Human Body Support Design Ming Zhang The Hong Kong Polytechnic University, Hong Kong S.A.R. (China) Crossing Cannulated Screws Fixation for Calcaneal Fracture Treatment. A Biomechanical Analysis and Preliminary Clinical Results Ming Ni, Jiong Mei, Wen-Xin Niu, Kun Li 2 Tongji Hospital of Tongji University, China; 2 Department of Orthopedics, Pudong New Area People s Hospital, China Development of Measurement System and Computation of Inverse Dynamics for Estimate the Trunk Muscle Force in Bicycle Pedaling Tomoki Kitawaki, Tatsushi Tokuyasu 2, Hisao Oka 3 Kansai Medical University, Japan; 2 Fukuoka Institute of Technology; 3 Okayama University, Japan The Study of the Contact Mechanics of the Patellofemoral Arthroplasty Jaryl CK Ng, Alex CT Choh,2, Andy KS Yew 3, Shi-Lu Chia 3, Desmond YR Chong,2 Department of Biomedical Engineering, ; 2 Engineering Design and Innovation Centre, ; 3 Department of Orthopaedic Surgery, Singapore General Hospital, Singapore Biomechanical Comparison of Ankle Arthrodesis and Ankle Arthroplasty Surgeries Yan Wang, Zengyong Li 2, Ming Zhang The Hong Kong Polytechnic University, Hong Kong S.A.R. (China); 2 Key Laboratory of High Efficiency and Clean Mechanical Manufacture, School of Mechanical Engineering, Shandong University, China Session 4B - Cellular Mechanobiology I Tuesday, 07 July 205 3:5pm - 4:45pm Seminar Rm 2 Session Chairs: Jianping Fu; Lisha Zheng Mechanobiology: A New Frontier for Human Pluripotent Stem Cells Jianping Fu University of Michigan, Ann Arbor, USA Mechanobiological Coupling of Hepatic Cells and Engineered Construction of 3D Liver Model Mian Long, Ning Li, Yan Zhang, Shouqin Lü, Chunfang Tong, Yu Du, Hao Yang Center of Biomechanics and Bioengineering and Key Laboratory of Microgravity (National Microgravity Laboratory), and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing, China Fluid Shear Stress Induced The Growth Factors Expression and Osteogenesis in Human Periodontal Ligament Cells Lisha Zheng, Yuchao Chen, Meijie Du, Jinpeng Gui, Luoping Chen, Yubo Fan Beihang University, China Quantitative Single-Cell Motility Analysis of Platelet-Rich Plasma-Treated Endothelial Cells in Vitro Tomoyuki Kawase, Takaaki Tanaka 2, Kazuhiro Okuda, Makoto Tsuchimochi3, Masafumi Oda 4, Toshiaki Hara 5 Institute of Medicine and Dentistry, Niigata University, Japan; 2 Department of Materials Science and Technology, Niigata University, Japan; 3 Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, Japan; 4 Institute of Research Collaboration and Promotion, Niigata University, Japan; 5 Niigata Institute of Technology, Japan Probing of Antigens on Malaria Infected Erythrocytes using Protein-Antibody Affinity Based Molecular Force Spectroscopy Himanshu Singh, Kripa Madnani 2, Jianshu Cao 3, Peter R. Preiser 2, Chwee Teck Lim ; 2 Nanyang Technological University, Singapore; 3 Massachusetts Institute of Technology, USA Session 4C - Biomicrofluidics II Tuesday, 07 July 205 3:5pm - 4:45pm Seminar Rm 5&6 Session Chairs: Tza-Huei (Jeff) Wang; Yilei Zhang Discerning Rare Disease Biomarkers by Nanoparticles and Droplets Tza-Huei (Jeff) Wang Johns Hopkins University, USA Single-Cell Proteomic Chip for Biomedical Research and Clinical Diagnostics Qihui Shi Shanghai Jiao Tong University, China Inhaled Vaccines via a Microfluidic Pulmonary Delivery System Leslie Yeo RMIT University, Australia Neuronal Culture on PDMS by Chemically Functionalized ECM Microenvironments Shreyas Kuddabbaya, Yilei Zhang Nanyang Technological University, Singapore 24 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 25

15 Towards A Micro Pneumatic Actuator with Large Bending Deformation For Medical Interventions Xinquan Liang,2, Chengkuo Lee 2, Hongliang Ren Biomedical Engineering, ; 2 Electrical&Computer Engineering, Isolation and Analysis of Extracellular Vesicles using Microfluidic Devices Zhiping Wang, Ruige Wu, Puttachat Khuntontong, Sai Kiang Lim 2, Soon Sim Tan 2, Ruenn Chai Lai 2 Singapore Institute of Manufacturing Technology, Singapore; 2 Institute of Medical Biology, Singapore Special Session - Low Power Electronics in Sport and Fitness Applications Tuesday, 07 July 205 3:5pm - 4:45pm Seminar Rm 7&8 Session Chair: Matthias Lochmann Basic Sensor Technologies and Latest Improvements for Low-Power Electronics in Sport and Fitness Applications Christian Hofmann, Nadine Lang, Matthias Lochmann 2, Matthias Struck Fraunhofer Institute for Integrated Circuits IIS, Germany; 2 Friedrich-Alexander-University Erlangen-Nuremberg, Germany Analysis of the Indoor Ball Tracking Precision of a Radio-based Real-time Locating System Thomas Seidl, Christoper Mutschler, Nicolas Witt, Matthias Völker, David Voll, Dino Poimann 2, Titus Czyz 2, Matthias Lochmann 2, Norbert Franke Fraunhofer Institute for Integrated Circuits IIS, Germany; 2 Friedrich-Alexander-University Erlangen-Nuremberg, Germany Technical and Sport-Scientific Validation of a Radio-Based Local Tracking System for Indoor Applications Thomas Seidl, Nicolas Witt, Matthias Völker, David Voll, Dino Poimann 2, Titus Czyz 2, Matthias Lochmann 2, Norbert Franke Fraunhofer Institute for Integrated Circuits IIS, Germany; 2 Friedrich-Alexander-University Erlangen-Nuremberg, Germany Evaluation of Passing Quality in Football by Means of a Radio-Based Local Tracking System Dino David Poimann, Titus Czyz, Thomas Seidl 2, Norbert Franke 2, Matthias Lochmann Friedrich Alexander University Erlangen-Nuremberg, Germany; 2 Fraunhofer Institute for Integrated Circuits, Germany Evaluation of Ball Handling in Football By Means of a Radio-Based Local Tracking System Dino David Poimann, Titus Czyz, Matthias Völker 2, Norbert Franke 2, Matthias Lochmann Institute of Sport Science and Sport, Friedrich-Alexander-University Erlangen-Nuremberg, Germany; 2 Fraunhofer Institute for Integrated Circuits, Germany Afternoon Tea Break 4:45pm - 5:5pm Session 5A - Spine & Bone Mechanics Tuesday, 07 July 205 5:5pm - 6:5pm Auditorium Session Chairs: Jaw-Lin Wang; Ching Chi Hsu Characteristics of Radiculomyelopathy Patients after Anterior Cervical Discectomy and Fusion: A Biopsychosocial Model Andy Chien, Dar-Ming Lai, Shwu-Fen Wang, Chih-Hsiu Cheng Cheng, Wei-Li Hsu, Jaw-Lin Wang National Taiwan University, Taiwan Micro & Nano structure and Mechanical Competence of Trabecular Bone in Knee Osteoarthritis William Lu The University of Hong Kong, Hong Kong S.A.R. (China) Numerical and Experimental Investigations of Spine-Pelvis-Femur Complex with Sacroiliac Joint Fractures Using Different Fixation Techniques Ching Chi Hsu, Chian Her Lee 2, Po Yuang Huang National Taiwan University of Science and Technology, Taiwan; 2 Taipei Medical University and Hospital, Taiwan Effect of the Different Degeneration Level on the Mechanical Response of a Lumbar L2-L3 Motion Segment- A Nonlinear Finite Element Analysis Xiao Zhitao, Wang Shaowu, Gong He 2 Dalian Medical University, China; 2 JiLin University, China Session 5B - Computational Biomechanics Tuesday, 07 July 205 5:5pm - 6:5pm Seminar Rm 2 Session Chair: Xiaobo Gong; Martin Buist A Numerical Study of Oxygen Transfer Efficiency in Capillaries Xiaobo Gong, Zhaoxin Gong, Huaxiong Huang 2 MOE Key Laboratory of Hydrodynamics, Department of Engineering Mechanics, Shanghai Jiao Tong University, China; 2 Department of Mathematics and Statistics, York University, USA A Coupled Mathematical Model of Glioblastoma Growth, Pre-Existing Vessel Co-Option, Angiogenesis and Blood Perfusion Yan Cai,2, Z.J. Zhou,2, Jie Wu 3, Zhiyong Li,2, Quan Long 4 State Key Laboratory of Bioelectronics, Southeast University, China; 2 School of Biological Science and Medical Engineering, Southeast University, China; 3 Shanghai Jiaotong University, China; 4 Brunel University, UK Quantitative Model of Colonic Smooth Muscle Relaxation Jing Wui Yeoh, Alberto Corrias, Martin Lindsay Buist 26 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 27

16 Session 5C - Biomedical Sensors & Wearables Tuesday, 07 July 205 5:5pm - 6:5pm Seminar Rm 5&6 Session Chairs: Haoyong Yu; Desmond Y.R. Chong Using Wearable Sensors to Detect Motion Symptoms for Parkinson Disease Dharamjeet Choudhary, Wann-Yun Shieh 2, Che-Kuan Lin 2 Department of Computer Science and Information Engineering, Chang Gung University, Taiwan; 2 Graduate Institute of Mechatronics, Chang Gung University, Taiwan Design of Unobtrusive Wearable Mental Stress Monitoring Device Using Physiological Sensor Thoriq Salafi, James Kah Chen Yong Development of a Wearable EEG Device for Anxiety Monitoring through Analysis of Occipital EEG Shruthi Suresh, Sharmila Jayakkumar, Yuchun Liu, Raye Chen-Hua Yeow National University Of Singapore, Singapore Development of Wireless Sensing and Optical Stimulation Module for Optogenetic Animal Study Meng-Chun Liu, Yu-Ting Li 2, Jia-Jin Jason Chen Institute of Biomedical Engineering, National Cheng-Kung University, Taiwan; 2 Instrument Technology Research Center, National Applied Research Laboratories,Taiwan Session 5D - Biomicrofluidics III Tuesday, 07 July 205 5:5pm - 6:5pm Seminar Rm 7&8 Session Chairs: Rong Fan; Guan-Yu Chen Single-Cell Highly Multiplexed Cytokine Analysis of Hematopoietic Malignancies Rong Fan Yale University, USA Low-Volume Multiplexed Proteolytic Activity Assay and Inhibitor Analysis through a Pico-Injector Array Ee Xien Ng, Miles A. Miller 2,3, Chia-Hung Chen,4 Department of Biomedical Engineering, ; 2 Center for Systems Biology, Massachusetts General Hospital, USA; 3 Department of Biological Engineering, Massachusetts Institute of Technology, USA; 4 Singapore Institute for Neurotechnology (SINAPSE), Singapore Pump Free 3D Microfluidic Cell Culture for Human Progenitor Liver Cell Differentiation Louis Ong Jun Ye,2, Edward Teng Yao Zhong, Jin Lin, Toh Yi-Chin,2 ; 2 SINAPSE, Singapore Institute of Neurotechnology, National University of Singapore, Singapore Graphene Oxide Nanosheets Modified with Single Domain Antibodies for Rapid and Efficient Capture of Cells Guan-Yu Chen, Zeyang Li 2, Christopher S. Theile 2, Hidde L. Ploegh 2 Institute of Biomedical Engineering, National Chiao Tung University, Taiwan; 2 Whitehead Institute for Biomedical Research, Cambridge, USA Congress Banquet Tickets for the congress banquet are not included in the registration fee and are to be purchased separately 6:30pm 9:30pm Programme Wednesday, 8 July 205 Plenary Lecture 3 Wednesday, 08 July 205 9:30am - 0:5am Auditorium Session Chair: James Goh Robotic Surgery Current State-of-the-Art and Emerging Trends Guang-Zhong Yang Imperial College, UK Morning Tea Break 0:5am - 0:45am Keynote 5 Wednesday, 08 July 205 0:45am - :5am Auditorium Session Chair: Siew Lok Toh High Frequency Ultrasound and its Biomedical Applications K. Kirk Shung University of Southern California, USA Short Break :5am - :30am Session 6A - Orthopaedics & Medical Devices Wednesday, 08 July 205 :30am - :00pm Auditorium Session Chairs: Alberto A. Suárez; Siew Lok Toh A Study of Frictional & Biomechanical Forces in a Trapezoidal Bracket Versus Rectangular Bracket and Periostin Activity Teresa Cobo, Alberto A. Suárez, Juan Cobo, Santiago Cal, Alvaro J Obaya University of Oviedo, Spain 28 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 29

17 The Study of Contact Pressure of a Customized Knee Spacer Using Finite Element Analysis Alex CT Choh,2, Jaryl CK Ng,2, Andy KS Yew 3, Shi-Lu Chia 3, Desmond YR Chong,2 Engineering Design and Innovation Centre, ; 2 Department of Biomedical Engineering, ; 3 Department of Orthopaedic Surgery, Singapore General Hospital, Singapore Patellofixator Design Specifications of a Device Assisting Medial Patello Femoral Ligament [MPFL] Reconstruction Sarthak Patnaik, Sudesh Sivarasu 2 Learning Trauma Med, Santander, Spain; 2 University of Cape Town, South Africa Study on Relationship of Pneumatization of Temporal Bone and Pulsatile Tinnitus Jiemeng Yang, Lizhen Wang, Shan Tian, Zhaohui Liu 2, Yubo Fan,3 School of Biological Science and Medical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, National Key Lab of Virtual Reality Technology, Beihang University, China; 2 Department of Radiology, Beijing Tongren Hospital, Capital Medical University, China; 3 National Research Center for Rehabilitation Technical Aids, China Effect of Head Down Tilt Traction Treatment on Degenerated Lumbar Spine Sicong Wang,2, Lizhen Wang,2, Yubo Fan,2,3 Beihang University, China; 2 School of Biological Science and Medical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, National Key Lab of Virtual Reality Technology, Beihang University, China; 3 National Research Center for Rehabilitation Technical Aids, China Session 6B - Cellular Mechanobiology II Wednesday, 08 July 205 :30am - :00pm Seminar Rm 2 Session Chairs: Xiaodong Chen; Yusuke Toyama Cell Damages under Mechanical and Oxidative Stresses Arthur FT Mak The Chinese University of Hong Kong, Hong Kong S.A.R. (China) Nanomechanical Mapping of Cellular Migration Xiaodong Chen Nanyang Technological University, Singapore Substrate Stiffness Regulates B-Cell Activation, Proliferation, Class Switch and T-Cell-Independent Antibody Responses In Vivo Chunyang Xiong Peking University, China Cell Spreading Size Regulates Size of Clathrin-Coated Pits through Tension Allen Liu University of Michigan, USA Regulation of Cell Adhesion and Tissue Tension during Apoptosis in Epithelium Xiang Teng,2, Roland Le Borgne 3,4, Yusuke Toyama,2,5 ; 2 Mechanobiology Institute, Singapore; 3 Institute of Genetics and Development of Rennes, France; 4 Université Rennes, UEB, France; 5 Temasek Life Sciences Laboratory, Singapore Session 6C - Biosignal Processing Wednesday, 08 July 205 :30am - :00pm Seminar Rm 5&6 Session Chairs: Cholid Badri; Sheng-Fu Liang Assessment Method for Bacterial Virulence Based on Ultraviolet and Visible (UV-Vis) Spectroscopy Analysis Cholid Badri, Budiman Bella 2, Anwar Soefi. Ibrahim, Sutarmo Setiadji University of Indonesia Graduate Program, Indonesia; 2 University of Indonesia, Faculty of Medicine, Indonesia Evaluating the Degree of Influence between Two Discrete-Time Fractional Gaussian Noises Yen-Ching Chang,2, Rou-An Shen, Sheng-Xuan Chou, Hsuan-Po Lin, Chan-Yin Huang, Fei-Yun Chang Chung Shan Medical University, Taiwan; 2 Chung Shan Medical University Hospital, Taiwan A Simplified Approach to Identify the Fetal ECG from abdecg and to Measure fhr H. Nair Ridhu, Rolant Gini J., Ramachandran Dr. K. I. Amrita Vishwa Vidyapeetham, India Effect of Different Occlusion Durations on the Assessment of Arterial Flow-Mediated Dilatation Jia-Jung Wang, Shing-Hong Liu 2, Chia-Chi Yang, Tsung-Lin Ho, Yong-Hong Pan, Wei-Kung Tseng 3 I-Shou University, Taiwan; 2 Chaoyang University of Technology, Taiwan; 3 E-Da Hospital, Taiwan Feasibility Analysis of Using EOG Signals to Perform Neural Feedback Training for Alpha Rhythms Enhancement Chih-En Kuo 2, Sheng-Fu Liang, Tsung-Hao Hsieh, Fu-Zen Shaw 2, Jen-Jui Hsueh 2, Yung-Hung Wang 3 Department of Computer Science and Information Engineering, National Cheng Kung University, Taiwan; 2 Department of Psychology, National Cheng Kung University; 3National Central University, Taiwan Human Heart Oscillatory Behavior during Atrial Fibrillation Based on Second Order System Nurul Ashikin Abdul-Kadir, Norlaili Mat Safri, Mohd Afzan Othman, Abdul Mutalib Embong 2 Universiti Teknologi Malaysia, Malaysia; 2 Universiti Teknologi Petronas, Malaysia Session 6D - Symposium on Bioengineering Related Thermo Fisher Scientific Wednesday, 08 July 205 :30am :00pm Seminar Rm 7&8 R&D in qpcr Analysis Jonathan Wang, San Francisco, CA R&D on Stem Cell Biology David Kuninger, Frederic, Maryland R&D on Synthetic Biology Jason Carte, Carlsbad, CA Lunch & Poster :00pm - 2:00pm 30 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 3

18 Reattaching Tendon to Bone Guy M Genin Washington University in St. Louis, USA Keynote 6 Wednesday, 08 July 205 2:00pm - 2:30pm Auditorium Session Chair: Sierin Lim Short Break 2:30pm - 2:45pm Session 7A - Cardiovascualr Disease Biomechanics & Devices Wednesday, 08 July 205 2:45pm - 4:5pm Auditorium Session Chairs: Ming Dao; Muhammad Jamil Cell Biomechanics versus Human Diseases Ming Dao MIT, USA Mathematical Modelling of Blood Perfusion and Oxygen Transport in the Cerebral Microvasculature of Ischemic Stroke Zeji Zhou, Z. Liu, Yan Cai, Zhiyong Li Southeast University, China Finite Element Shape Optimization for Biodegradable Poly (lactic-co-glycolic acid) Stents Meng Guo,2, Zhaowei Chu,2, Yuanming Gao,2, Jie Yao,2, Yubo Fan,2,3 Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, International Research Center for Implantable and Interventional Medical Devices, Beihang University, China; 2 Beijing Key Laboratory for Optimal Design and Evaluation Technology of Implantable & Interventional Medical Devices, China; 3 National Research Center for Rehabilitation Technical Aids, Beijing, China Pre-surgical Simulation for Quantification of the Coronary Blood Flow Improvement after Coronary Artery Bypass Graft Surgery Jun-Mei Zhang,2, Tong Luo 3, Jia Lin Soon,2, Ning Kang, Kenny Yoong Kong Sin,2, Swee Yaw Tan,2, Victor Tar Toong Chao, Teing Ee Tan,2, Chong Hee Lim,2, Mathew Jose Chakaramakkil, Adrian Seng Wae Ooi, Aileen Mae Lomarda, Ru San Tan,2, Feiqiong Huang,2, Jia Ing Wong, Thu Thao Le, Fei Gao, Boyang Su, Liang Zhong,2 National Heart Center Singapore, Singapore; 2 Duke-NUS Graduate Medical School, Singapore; 3 Departments of Biomedical Engineering, Indiana University-Purdue University Indianapolis, USA Morphological and Hemodynamic Changes of the Carotid Siphon in the Moyamoya Disease Muhammad Jamil, Mehnaz Huq, Heidi Kang 2, Zhi Rui Lee 2, Phua Hwee Tang 3, Choon Hwai Yap Department of Biomedical Engineering, National University of Singapore; 2 Hwa Chong Institution, Singapore; 3 KK Women s and Children s Hospital, Singapore Hemodynamics Investigation of Stented Valves Implantation in the Vena Cava to treat Tricuspid Regurgitation Munirah Ismail, Yen Ngoc Nguyen, Foad Kabinejadian, Hwa Liang Leo Biofluid Mechanics Research Lab (NUS), Singapore Session 7B - Molecular Biomechanics & Mechanobiology Wednesday, 08 July 205 2:45pm - 4:5pm Seminar Rm 2 Session Chairs: Masahiro Sokabe, Pakorn Kanchanawong Molecular and Biophysical Mechanisms Underlying Force Dependent Dynamics of Actin Cytoskeletons Masahiro Sokabe,2 Nagoya University Graduate School of Medicine, Japan; 2 Mechanobiology Institute/ Natinal University of Singapore Mechanical Mechanism of the Biased Branching Direction of Actin Filaments Tong Li, YuanTong Gu Queensland University of Technology, Australia Mechanical Activation of Talin, α-catenin, and Vinculin Jie Yan BCH Domain Proteins as the P(L)Acemakers in Cancer- and Neuro-Signaling Boon Chuan Low Mechanobiology Institute and Nanoscale Imaging of Cadherin-Mediated Cell-Cell Junctions Pakorn Kanchanawong Nuclear Envelope Proteins Regulate Proliferation of Vascular Cells in Response to Mechanical Strain Ying-Xin Qi, Yue Han, Zong-Lai Jiang Institute of Mechanobiology and Medical Engineering, Shanghai Jiao Tong University, China 32 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 33

19 Session 7C - Biomaterials II Wednesday, 08 July 205 2:45pm - 4:5pm Seminar Rm 5&6 Session Chairs: Yuan Cheng; Kuofeng Chou Mechanical Properties of Bombyx mori Silk based on Molecular Dynamics Simulations Yuan Cheng, Yong-Wei Zhang, Dechang Li 2, Baohua Ji 2 Institute of High Performance Computing, A*STAR, Singapore; 2 Biomechanics and Biomaterials Laboratory, Dept of Applied Mechanics, Beijing Institute of Technology, Beijing, China Tissue Engineering Silk-doped PVA Hydrogels for Intervertebral Disc Replacements: From a Biomechanics Perspective Puay Yong Neo, Alex Sheng Ru Tay, Xiaojuan Chen, James Cho-Hong Goh, Siew Lok Toh Content of Titanium Dioxide and Applied Electric Field Effects on UV Screening Performance of Chitosan Based Dressing Kuofeng Chou, Liwen Wang Yuanpei University, Taiwan Editors: Session 7D - Meet the Editors Wednesday, 08 July 205 2:45pm 4:5pm Seminar Rm 7&8 Session Chair: Savio Woo Prof Nitish Thakor Editor-in-Chief, Medical & Biological Engineering & Computing Prof Kam Leong Editor-in-Chief, Biomaterials Prof Leslie Yeo Editor, Biomicrofluidics (American Institute of Physics) Closing Address 4:5pm - 4:45pm Auditorium Adipogenic Potential of Injectable BFGF-Loaded Decellularized Adipose Tissue Matrix Shipin Zhang, Qiqi Lu, Kai Xuan Collin Chong, Thulasi Thiruvallur Madanagopal, Wei Seong Toh,2 Faculty of Dentistry, ; 2 Tissue Engineering Program, Life Sciences Institute Fabrication of Cellulose-Gelatin Based Endothelialed Vascular Graft with SMCs/ADSCs Seeding in Bioreactor Ts-Ching Yu, Ming-Long Yeh 2 National Chen Kung University, Taiwan; 2 National Chen Kung University, Taiwan Construction of Tissue-Engineered Vascular Media Using Plastically Compressed Smooth Muscle Cell-Seeded Collagen Gels Ho-Yi Tuan-Mu, JIn-Jia Hu,2 Department of Biomedical Engineering, National Cheng Kung University, Taiwan; 2 Medical Device Innovation Center, National Cheng Kung University, Taiwan 34 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 35

20 List of Posters ID: 74 / PO: FEM Modeling for Performance Evaluation of Microwave ablation Applicator When Using T Prong Monopole Antennas Montree Chaichanyut, Supan Tungjitkusolmun King Mongkut s Institute of Technology Ladkrabang, Thailand ID: 62 / PO: 2 Discrimination of Clinical Microorganism Using Raman Spectroscopy and Pattern Recognition Techniques Chi-Chang Lin, Cheng-Yao Lin Tunghai University, Taiwan ID: 88 / PO: 3 Effects of Low-Intensity Exercise Training on Tissue Oxygen Saturation of Lower-Extremity in Community-Dwelling Older Adults Jian Guo Bau, Yu Fang Chung 2, Hua Chien Lin Hungkuang University, Taiwan; 2 Tunghai University, Taiwan ID: 9 / PO: 4 Quantitative Segmentation and Analysis of Microtubule Network Based on Enhanced Fluorescence Microscopy Image Zhen Zhang, Pakorn Kanchanawong,2 Mechanobiology Institute, ; 2 Department of Biomedical Engineering, ID: 45 / PO: 5 Altered Somatosensory Processing in Patients with Paroxysmal Kinesigenic Dyskinesia: an MEG Study Fu-jung Hsiao, Wan-Yu Hsu, Yung-Yang Lin National YangMing Univ., Taiwan ID: 56 / PO: 6 Preliminary Study on Frequency Based Parameters of Myoelectric Signal Using Single Channel Myoelectric Module Ilham Priadythama, Susy Susmartini Laboratory of Product Planning and Design, Industrial Engineering Department, Universitas Sebelas Maret, Indonesia ID: 5 / PO: 7 Development of Long-Term Reusable Glucose Oxidase Enzyme Electrode and its Application in Blood Sugar Inspection Cheanyeh Cheng, Den-Ten Chung 2, You-Zu Lin Chung Yuan Christian University, Taiwan; 2 Ten-Chen General Hospital, Taiwan ID: 20 / PO: 8 A Bioinformatics Approach to Investigating Significant Genes of Hepatocellular Carcinoma from Microarray Expression Data Liang-Tsung Huang, Yun-Ting Lai Mingdao University, Taiwan ID: 7 / PO: 9 Wireless System for Monitoring Body Temperature David Tolar, Renata Bischofova, Ludek Hyncik, J. Gallo 2 University of West Bohemia, Czech Republic; 2 Palacky University Olomouc, Czech Republic ID: 08 / PO: 0 An Integrated Processing System for Temporal Neuron Analysis Han-Wei Dan, Chia-Yi Tseng, Cheng-An J. Lin, Yuh-Show Tsai Chung Yuan Christian University, Department of Biomedical Engineering, Taiwan ID: 57 / PO: Estimation of the Shell Elasticity of Lipid-Coated Microbubbles Based on the Linearized Marmottant Model Jenho Tsao National Taiwan University, Taiwan ID: 9 / PO: 2 Development of a Modular FPGA Based Digital Beamformer for PC Based Ultrasound Imaging System Pratondo Busono, Yaya Suryana, Arief Barkah, Rony Febryarto, Teguh Handoyo, Riyanto Riyanto, Ario Fitrianto Center for Information and Communication Technology, BPPT, Jakarta, Indonesia ID: 23 / PO: 3 The Development of Pancreatic Cancer CAD System for CT and US Images Jenn-Lung Su, Guan-Wen Chen, Yu-Chieh Hsu, Chia-Hung Pan, Ming-Hui Lin 2 Chung Yuan Christian University, Taiwan; 2 Taoyuan General Hospital, Taiwan ID: 229 / PO: 4 Wavelength Optimization Oo Spectral Near- Infrared Optical Tomography Using Available Laser Diodes Min-Chun Pan, Liang-Yu Chen, Chung-Chen Yan, Min-Cheng Pan 2 Graduate Institute of Biomedical Engineering, National Central University, Taiwan; 2 Department of Electronic Engineering, Tungnan University, Taiwan ID: 249 / PO: 5 Diagnostic Tool for PCOS Classification Balakrishnan Padmapriya, T. Kesavamurthy PSG College of Technology, Coimbatore, India ID: 6 / PO: 6 Vein Tracking Using 880nm Near Infrared and CMOS Sensor with Maximum Curvature Points Segmentation Anggunmeka Luhur Prasasti, Richard Mengko, Widyawardana Adiprawita Computer Engineering, School of Electrical Engineering, Telkom University, Indonesia ID: 24 / PO: 7 The Influence of Laminin-Modified Electrospun Silica Nanofibers on Neuronal Growth and Survival Wen Shuo Chen, Ling Yu Guo, Chia Chun Tang, Ting Yu Chin 2, Mong-Lin Yang 3, Yui Whei Chen-Yang Department of Chemistry, Center for Nanotechnology, Center for Biomedical Technology, Chung Yuan Christian University, Taiwan; 2 Department of Bioscience Technology, Chung Yuan Christian University, Taiwan; 3 Department of Science, Concordia University, USA ID: 63 / PO: 8 Mechanical Regulation of Cell Behaviors on Multi-Photon Photochemical-Crosslinking-Based Bovine Serum Albumin Only Micropillars with Extremely Low Stiffness Minghui Tong, BP Chan The University of Hong Kong, Hong Kong S.A.R. (China) ID: 98 / PO: 9 Hybrid Artificial Protein-Polymer Hydrogels As Well-Defined Cellular Matrices. Wilhelm W. Chen, Eileen Fong School of Materials Science and Engineering, Nanyang Technological University, Singapore ID: 20 / PO: 20 Chondrocyte Sheets Based on TGF-B Modified Small Intestinal Submucosa Membrane for Tendon-Bone Healing Hsia-Wei Liu, Chih-Hwa Chen 2 Fu Jen Catholic University, Taiwan; 2 Taipei Medical University, Taiwan ID: 46 / PO: 2 In Vivo Tissue-Engineering Vascular Graft by PRP Immersed Rolled PLA Ying-Chiang Ho, Ming-Long Yeh Institute of Biomedical Engineering, National Cheng Kung University, Taiwan ID: 204 / PO: 22 The Flexural Characteristic of Endodontic Post Materials Yao-Ning Lei, Sin-Yan Wu 2, Ting-Shen Lin 2 Department of dentistry, E-Da Hospital, Taiwan; 2 Department of Biomedical Engineering, I-Shou University, Taiwan; ID: 62 / PO: 23 Electrospun Scaffolds of Glycidyl Methacrylate Hyaluronic Acid for the Application of Adhesion Barrier Tai-Shune Chiang 2, Ming-Fa Hsieh, Chin-Ming Chu 2 Department of Biomedical Engineering, Chung Yuan Christian University, Taiwan; 2 Department of Chemical Engineering, National United University, Taiwan ID: 65 / PO: 24 Mineralization of Calcium Phosphate on Chitosan/PLA Composited Electro-Spun Nanofiber Mats Chi-Chang Lin, Yu-Rou Lee Tunghai University, Taiwan 36 7th WACBE World Congress on Bioengineering 7th WACBE World Congress on Bioengineering 37

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