5th ANNUAL SEMINAR OF TISSUE ENGINEERING AND MEDICAL, DENTAL AND VETERINARY BIOMATERIAL RESEARCH GROUP (BRG) SESSION 1. TISSUE ENGINEERING AND HEALING

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1 1 5th ANNUAL SEMINAR OF TISSUE ENGINEERING AND MEDICAL, DENTAL AND VETERINARY BIOMATERIAL RESEARCH GROUP (BRG) Time: Tuesday, June 01, 2004 Location: Biomedicum, Helsinki, Finland 9:00-9:30 REGISTRATION AND COFFEE 9:30 Pertti Törmälä Opening of Seminar SESSION 1. TISSUE ENGINEERING AND HEALING Chairman of Session; Prof. Timothy Wright 9:40 PLENARY LECTURE Michael Silbermann The Sheep Sternum - A Model for in vivo Studies on Bone Healing 10:30 Katja Puumanen Guided bone regeneration of Experimental Maxillary Alveolar Cleft Defects in Growing Rabbits with a New Bioabsorbable Composite Membrane of Polyactive and Bioactive Glass n:o :45 Ville Ellä Material Technical Properties of Fibrous Scaffolds 11:00 Satu Länsman Scleral Buckling Bioabsorbable Poly-L/D-lactide Implants Can Provide Sufficient Indentation in Experimental Rabbit Model As Can Be Shown with CT

2 2 11:15 Heikki Penttilä Use of Prefabricated Microvascularied Perichondrial Flaps and Bioabsorbable Polylactide Nonwoven Scaffolds for Cartilage Tissue Engineering 11:30 Henna Niiranen In Vitro Hydrolysis of Osteoconductive Composite 11:45 Eerik Skyttä Clinical Experience with Bioreconstructive Joint Scaffolds 12:00 Yrjö Konttinen Guidelines of New Application for the Tissue Engineering Center of Excellence 12:15-13:00 LUNCH SESSION 2. BIOMECHANICS AND MODELLING Chairman of Session; Prof. Seppo Santavirta 13:00 Rami Korhonen Biomechanical Modelling of THR 13:15 Arto Koistinen Improvement of Human Bone Screws with AD Coatings 13:30 Mikko Selenius Five Most Commonly Used Hip Implants in Simulator Surface Characteristics and Particles 13:45 Joanna Sierpowska Impedance vs Mechanical Testing for Human Bone 14:00 Jari Leskinen Friction and Wear of Cartilage Against Coatings 14:15 Mirjami Kiuru Novel Coating Developments 14:30-14:45 BREAK WITH POSTERS

3 3 SESSION 3. CELLULAR MECHANISMS Chairman of Session: Prof. Michael Silbermann 14:45 Ville Waris Bone Morphogenetic Proteins 15:00 Jami Mandelin RANK-Ligand System in Bone 15:15 Guofeng Ma ADAMs in Cell Fusion 15:30 Arzu Beklen Activation of MMP-3, -8 and -9 in Peri-Implant and Periodontal Tissues 15:45 Mika Hukkanen Imaging in Implantology 16:00 COFFEE BREAK General Discussion 16:30 Seppo Santavirta End of the Seminar

4 BRG 2004 Posters Ainola M, Mandelin J, Konttinen YT: Extracellular Matrix Proteinases in Pannus Invation in Rheumatoid Arthritis Ashammakhi N, Renier D, Arnaud E, Marchac M, Ninkovic M, Donaway D, Jones B, Serlo W, Laurikainen K, Törmälä P, Waris T: Multicenter Study on the Use of Biosorb Osteofixation Devices in 165 Cranial and Maxillofacial Cases: A Multicenter Report Knuutila K, Tiainen J, Veiranto M, Suokas E, Waris T, Törmälä P, Kaarela O, Ashammakhi N: Novel Multifunctional Tacks: Pull-Out Strength of Ciprofloxacin-Releasing Tacks Länsman S, Pääkkö P, Ryhänen J, Hirvelä H, Kellomäki M, Ellä V, Törmälä P, Waris T, Ashammakhi N: New Bioabsorbable Scleral Buckling Implants: Histological Evaluation in Rabbits Mandelin J, Hukkanen M, Li T-F, Liljeström M, Santavirta S, Konttinen YT: Cathepsin K Expression in Human Osteoblasts Oudina K, Potier E, Arnaud E, Ellä V, Kellomäki M, Ashammakhi N, Petite H: Bone Tissue Engineering Using Proliferation Mesenchymal Stem Cells Towards and PLDLA Scaffolds Penttilä H, Tuominen P, Waris T, Baer G, Rorarius M, Kalliovalkama J, Sand J, Ashammakhi N: Development of New Method to Follow-Up Tissue Flaps Using Surface Sensor Pulse Oximeter Stoop R, Sapei L, Gaissmaier C, Scharstuhl A, Kellomäki M, Ellä V, Ashammakhi N, Törmälä P, Hämmerle H: Cartilage Tissue Engineering Using Chondrocytes and Woven P(L/D)LA Scaffolds Johanna Tiainen, Sanna Leinonen, Jouko Ilomäki, Esa Suokas, Pertti Törmälä, Timo Waris, Nureddin Ashammakhi: Holding Power of Bioabsorbable Polylactide/Polyglycolide Screws (Biosorb and Lactosorb) and Tacks to Human Cadaver Parietal Bone Tiainen J, Soini Y, Törmälä P, Waris T, Ashammakhi N: Long-Term Histological Evaluation of Bioresorption of Self-Reinforced Polylactide- Polyglycolide 80/20 Screws to Resorb Completely in Rabbit Cranial Bone Tiainen J, Soini Y, Suokas E, Veiranto M, Törmälä P, Waris T, Ashammakhi N: Tissue Reactions to Multifunctional Bioabsorbable Ciprofloxacin-Releasing Polylactide- Polyglycolide 80/20 Screws in Rabbit Cranial Bone Tiainen J, Veiranto M, Koort J, Suokas E, Törmälä P, Waris T, Kaarela O, Ashammakhi N: Bone Tissue Concentrations of Ciprofloxacin Released from Polylactide-Polyglycolide 80/20 Screws Implanted in Rabbits Cranial Bone

5 Vaananen P, Koistinen A, Santavirta S, Korhonen RK, Lappalainen R: Simulator Study on the Effect of Abduction Angle on the Performance of Uhmwpe Acetabular Cup of Total Hip Replacement Vesala A-L, Kallioinen M, Törmälä P, Kellomäki M, Waris T, Ashammakhi N: Healing of Cranial Bone Defects with Guided Bone Regeneration Virtanen H, Tuppurainen J, Toropainen A, Lappalainen R: Interaction of Mobile Phones with Superficial Implants Waris E, Kelly CP, Andrus L, Waris T, Jackson IT, Ashammakhi N: Study on the Effect of Transphyseal Bioabsorbable Screws on Growth Retardation in Rabbit Femur Niemelä S-M, Ikäheimo I, Koskela M, Veiranto M, Suokas E, Törmälä P, Waris T, Ashammakhi N, Syrjälä H: Study of the Effect of Ciprofloxacin-Releasing Bioabsorbable Implant on Staphylococcus Epidermidis Attachment and Biofilm Formation in Vitro Dabernig W, Geley T, Richter E, Fritsch H, Piza H, Tukiainen M, Kellomäki M, Ashammakhi N, Ninkovic M: Study of New Bioactive Glass Fibre-Based Scaffolds Tissue Engineeering of Bone in Experimental Bone Defects Serlo W, Törmälä P, Waris T, Ashammakhi N: Correction of Trigonocephaly with Bioabsorbable Tacks and Plates