What the Indiana CTSI HUB is Trying to Accomplish
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- Penelope Freeman
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1 What the Indiana CTSI HUB is Trying to Accomplish Bill Barnett Director, Information Infrastructures, Indiana CTSI IU School of Medicine and Indiana University Information Technology Services disclaimer: I don t care about Any Particular Technology
2 What is a CTSI? An Institutional NIH Clinical and Translational Science Award (CTSA) to improve human health by transforming the research and training environment to enhance the efficiency and quality of clinical and translational research (see AKA Bench to Bedside Currently 46 but eventually 60 centers in a national network 5 National Strategic Goals: (development, approval, activation, enrollment, and completion of Clinical Trials) (recruit, educate, train, and promote clinical and translational investigators) (facilitates researcher networking across national institutions and topic domains, creating a virtual community) (moving discoveries through first time in humans studies) (promote the translation of the results of research into practice and public policy) What is the Indiana CTSI? A Statewide Health Care research partnership (IUSM, IU, Purdue, Notre Dame) Mission: Increase translational research to improve the health (and economy) of the Indiana population to:
3 What are the Indiana CTSI Programs? I. Create Translational Research Acceleration Programs and Support Pilot Projects. Project Development Teams (PDTs) and Indiana CTSI Pilot Funding Opportunities II. Train a new cadre of Translational Researchers. Research, Education, Training, and Career Development Bioethics and Subject Advocacy Community Health Engagement Program (CHEP)
4 What are the Indiana CTSI Programs? (continued) Participant and Clinical Interaction Resources (PCIR integrate clinical facilities and patient recruitment), the Indiana Clinical Research Center (ICRC (previously GCRC) to support clinical trials) the Clinical Research Resource Center (CRRC outpatient clinical trials) Translational Technology Resources (TTR), in other words Cores Research Ethics, Education, and Policy (REEP) and Regulatory Knowledge Support (RKS) Partnerships with Clarian, Lilly, WellPoint, Cook, Fairbanks, and other non-profit and forprofit health care entities What Is the Indiana CTSI HUB? The Web Portal for Indiana CTSI translational activities A Repository of Indiana CTSI program information and datasets Integrated Tools that support translational programs
5 What is the HUB cyberinfrastructure? A research virtual organization customization of Joomla! Web 2.0 component-based CMS (3700 publicly available components) based on NanoHUB. Federated Identity Management: use your institutional login to partner statewide or nationally through InCommon/Shibboleth HUBzero Consortium (Purdue, Indiana U., Clemson, and Wisconsin) has formed to ensure a progressive software roadmap, sustainability, licensing, and support for HUB software Ontological Mapping of HUB content in partnership with the National Center for Biomedical Ontology What Goals does the HUB have? Be the central gateway for Indiana translational activities Ease of use and easily discoverable services Support Web Services based interoperability Support federated identities for inter-institutional collaboration * Ontologically-based content tagging to ease discovery * A sustainable business model for the software Part of our partnership with Purdue (frankly) * - cyberinfrastructure in development
6 Internal Grant Management System Customized from the Open Journal System software II. III. IV. Train a new Cadre of Translational Researchers. Foster Robust Community Engagement Build Facile and Comprehensive Research Resources and Technologies Integrated Search of HUB Content (Publications, Grants, PubMed, Clinical Trials, Cores, Contributions, Members) HUB Component
7 Ranked, Citable Content Submissions (Documents, Presentations, Animations, Simulations) HUB Component Interactive Translational Technologies and Resources (TTR) (Core Service Discovery, ultimately a Marketplace) Custom Component
8 In Progress: Community Health Engagement Program (CHEP) (Community Portal) Custom Component In Progress: Private Group Collaboration Tool (File Sharing, , Fine Grained Group Management, HIPAA data)
9 In Progress: Industry Partner Discovery Tool (Search Industry Tech Transfer Officers by sub-specialty) What is Next for the Indiana CTSI HUB? Surveys Private Discussion Forums (specifically in support of Grant Review) E-Forms Jobs or Job Candidate postings Shared Storage Newsletters and list support Knowledge Base RSS Feeds
10 What ELSE is Next for the Indiana CTSI HUB? Open Source release of HUBzero Software (LGPL license) Faculty profiles to support Research Networking VIVO (Cornell), Loki (Iowa), Profiles (Harvard), or Digital CV (Pittsburgh) Patient Recruitment possibly Vanderbilt s Research Match Adopt a Clinical Trials Management System Adopt Vanderbilt s REDCap Clinical Data Management system Promote HUB as Translational Resource for other CTSAs Develop Network Analysis and a Recommender system How are we doing so far? Statewide scope creates need for basic communication and discovery Grant Program went from 33 to 104 applications the first year using the online review tool HUB most heavily used by Grant or Program Administrators Simple but effective tools have proven most utilized
11 The Indiana CTSI HUB Team Bill Barnett (Lead): Lilith Reeves (Chief Scientist): Anurag Shankar (Technical Lead): Mike McLennan (HUB Architect): Bob Davis (Usability): Joe Hunt (Evaluation): Samantha Scahill (Content Management): Jere Odell (Education and Bioethics): Elaine Skopelja (Library Informatics): Beth Whipple (Library Informatics): Craig Sanders (Software Engineering): Jim Mullen (Software Engineering): Michael Grobe (Software Engineering): Steve Snyder (Systems Engineering):
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