General Response Rates

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1 General Response Rates 42 Responses 28 Programs stated that they had a PharmD/PhD program and typically responded to questions about PharmD/PhD Training 16 Programs stated that they had a Clinical Pharmaceutical Scientist (or similarly named) Program and responded to questions about CPS programs.

2 Do you currently offer or plan to offer a graduate program in the Clinical Pharmaceutical Sciences? Yes No 45.2% 54.8%

3 Which of the following describes your School s/university s programmatic offerings for a PhD training in the Clinical Pharmaceutical Sciences? 30.4% (7) Formalized Program Informal Program Planning a Program 56.5% (13) 13.0% (3)

4 Which of the following describes the status of a combined or joint PharmD/PhD Program at your institution? 30.0% (12) Currently Offer a PharmD/PhD Planning on Offering a PharmD/PhD No Current Plans 55.0% (22) 15.0% (6)

5 What is the primary background of admitted students entering your program? Internal domestic applicants 27.6% (17) External domestic applicants International applicants 58.6% (17) 13.8% (4)

6 Which best describes the educational prerequisites for students entering your clinical pharmaceutical scientist graduate program? 43.8% (7) 37.5% (6) Requires a PharmD Requires a health sciences doctorate/masters Accepts students with related BS or graduate degrees 18.8% (3)

7 Which best describes the admission requirements for your program? 0.0% 38.9% (7) 33.3% (6) 27.8% (5) Active professional license in our state Health professional background independent of licensure status Domestic or international students with a health professional degree Any qualified domestic or international students

8 Which of the following best describes the primary advisor structure? 18.8% (3) 25.0% (4) Single individual as their primary mentor Either a single individual or coadvisors as their primary mentor(s) At least two individuals as their primary mentors (i.e. co advisors) 56.3% (9)

9 Describe your Qual or Comp Exam (17 responses) Preliminary exam Students must complete a detailed written research proposal and make an oral presentation of the proposal. Written exam, NIH mini grant proposal, oral defense The examination for PhD candidacy has both a written and oral component. The written component is a research proposal, written in standard NIH format, of their dissertation project. This is provided to the committee 2 4 weeks in advance of the oral qualifying exam and the committee members must approve of the written proposal before the student can move to the oral qualifying examination. The oral examination focuses on the student's comprehensive knowledge base in the graduate program, and while typically focused to some degree around their dissertation proposal can and does include questions from all their required graduate courses and other courses taken. Our qualifying exam consists of the student preparing a 10 page NIH style written grant proposal followed by an oral defense of that proposal in front of their graduate committee. Student in the clinical scientist training program must have a aim of that proposal consisting of a human study. For the Doctor of Philosophy program one preliminary written examination is required. With successful completion of the written examination an oral examination is then required. These examinations may be taken by the student when a majority of the plan of study has been completed. Further, these examinations must precede presentation of the dissertation defense at least by two semesters. students must have acceptable GRE scores We do not have a clinical pharmaceutical science graduate program. However, the general exam in our traditional graduate program is typically open book in which the students are required to address a number of topics over a few days. We require the candidate to pass both a written exam and oral presentation. Students prepare a grant proposal for the written examination. The oral examination covers the proposal and other areas at the discretion of the committee. WE don't currently have this program which is why I have skipped most of these questions Evaluation of completed didactic coursework N/A The development of the individual as an independent research scientist is a critical component of the Ph.D. degree. The potential for such development is assessed on the basis of both mastery of subject matter and research competency as judged in the context of written and oral examinations administered at the level of the department. Students are admitted to candidacy on the basis of completing required coursework and examinations as required and the recommendation of the Faculty Advisor, Student Advisory Committee and Graduate Program Director. Advancement to candidacy should preferably take place prior to initiating the third academic year in the program. Written Comprehensive Exam In Medicinal Chemistry, cumulative examinations will be given whereas in the Departments of Pharmaceutics and Pharmacy a written comprehensive examination will be given. The written examination(s) generally focus(es) on the subject matter deemed critical as a foundation in the particular program. The written examination is largely based on material covered in required course work and its application to theoretical and practical problems. Individual department guidelines should be consulted for greater detail. The written examination is administered by the student's department. In the event of failure of the written comprehensive examination, the student, with the approval of the Director of the Pharmaceutical Sciences Graduate Program, may be permitted to repeat the written examination. The Director of the Pharmaceutical Sciences Graduate Program should be notified in writing of the outcome of the written exam by the student s Program Director. Students prepare a research proposal, take a written examination, and complete an oral examination. Exam questions may, but do not have to, have direct relevance to the student's research project. Oral and Written qualifying exam knowledge of clinical subject and of research methods by written proposal for dissertation. Students prepare a written proposal for a research study. Oral questioning is based upon the written proposal. The qualifying exam is given after two years of didactic course work in core areas. Exam questions are designed to integrate core subject areas (PK/PD, Drug Metabolism, Pharmacogenomics, Experimental Design/Data Analysis, Pharmaceutical Analysis, Evidence Based Medicine). The content emphasized in the qualifying exam is centered on material covered in course work. However, the exam is not be fact based but instead integrates the skills and knowledge acquired from course work, research rotations and clinical experiences to all students to demonstrate creative thinking and problem solving ability in addition to breadth and depth of core knowledge. Competency in translational research is demonstrated by the ability to propose hypotheses, identify specific aims, and design experiments from the evaluation of scientific literature and the interpretation of in vivo and in vitro data. Students must pass the qualifying exam before proceeding with the preliminary oral exam and dissertation prospectus,

10 Which of the following best describes the qual or comp exam requirements? 13.3% (2) 33.3% (5) Demonstrate their ability to design a research study in humans 53.3% (8) Demonstrate their ability to design research in humans, but this is not a requirement No requirements to demonstrate ability to design research in humans

11 Which of the following best describes the composition of graduate dissertation committees in your Clinical Pharmaceutical Scientist Program? 7.7% (1) Required to have individual with clinical practice expertise Students are not required, but frequently have individuals with clinical practice experience 46.2% (6) Students rarely have, and are not required to have, individuals with clinical practice expertise 46.2% (6)

12 Which of the following best describes the dissertation research requirements regarding human research in your CPS Program? 38.5% (5) 0.0% 15.4% (2) Required to have the majority of their thesis as prospective human clinical study Required to have a significant portion (e.g., a thesis chapter) as a prospective human clinical study 46.2% (6) Required to have a clinical component to their research which includes human cells or clinical retrospective data No requirement with respect to human based studies

13 Which of the following best describes the research rotation requirements your CPS Program? 7.1% (1) 7.1% (1) 28.6% (4) One rotation prior to selecting an advisor. Two or more rotations prior to selecting an advisor. No rotation requirments before selecting an advisor. Students select advisors prior to entry into the program. 57.1% (8)

14 Which of the following best describes the curricular offerings for students in your CPS Program as compared to traditional PhD offerings? 20.0% (3) 33.3% (5) Very different set of core courses Some separate core courses 26.7% (4) The same core courses but separate elective offerings The same core and elective offerings 20.0% (3)

15 Clinical Pharmaceutical Sciences 14. Please state if each of the following are required (R); elective (E); or Neither (N) <u>didactic elements</u> of your Clinical Pharmaceutical Scientist Graduate Program: Answer Options Required Elective Neither Response Count Biostatistics Advanced Statistical Methods Ethics of Clinical Research Pharmacokinetics Modeling and Simulation Pharmacogenetics Grant Writing Teaching Methods Pharmacoepidemiology Clinical Trial Design Method for Assessment of Health Outcomes Biomarker Validation Drug Metabolism / Transport Advanced Pharmacotherapy Question Totals answered question 16 skipped question 29

16 Which of the following describes the clinical experiential opportunities during the PhD training portion of your Clinical Pharmaceutical Scientist Program? 28.6% (4) 42.9% (6) All students are required to have clinical rotations 14.3% (2) 14.3% (2) The majority of students have clinical rotations/clinical practices experiences but they are not required Some students have clinical rotations/clinical practice experiences but they are not required Few to no students have clinical rotations/clinical practice experiences

17 Which of the following best describes the IRB submission requirements for CPS Students? 21.4% (3) 28.6% (4) Required to prepare an IRB submission 50.0% (7) The majority of the students prepare an IRB submission but not required Few students prepare an IRB submission

18 Which of the following best describes the publication requirements for CPS Students? 23.1% (3) 0.0% Required to have published at least one manuscript Required to have published at least two manuscripts 76.9% (10) There are no publication requirements

19 Clinical Pharmaceutical Sciences 18. Your Clinical Pharmaceutical Scientist Graduate Program currently <u>pays</u> for: Answer Options Response Average Response Total Response Count Stipend support (amount) In-state tuition (amount or percent) Out-of-state tuition (amount or percent) Fees (amount or percent) 24, , ,364.64* 26, ,011.10* 40, * 3, answered question 12 skipped question 33 * Mixed response because some are as percent and others are as total amount

20 Which of the following describes your programs position with respect to external health professional employment? 8.3% (1) Allowed Encouraged Discouraged Not allowed 33.3% (4) 58.3% (7) 0.0%

21 Which of the following describes the primary mechanism for student stipend support in the early years within your graduate program? 6.3% (1) 18.8% (3) 50.0% (8) Supported by teaching assistantship Supported by research assistantship Supported by provision of clinical services Other 25.0% (4)

22 Clinical Pharmaceutical Sciences 21. How many years of support are provided by the institution (i.e. not by primary mentor grant support)? Answer Options Response Count 16 answered question 16 skipped question 29 Number Response Date Response Text 1 Aug 24, :38 PM 2 2 Aug 24, :08 PM 1 3 Aug 25, :37 PM 2 4 Aug 25, :20 PM 2 5 Aug 25, :37 PM varies; 2 or less considered optimal 6 Aug 26, :25 AM 4-5 years 7 Aug 26, :53 PM 5 8 Aug 26, :43 PM 0 9 Sep 1, :38 PM 4 10 Sep 1, :42 PM Usually 2 11 Sep 5, :46 PM 2 12 Sep 8, :22 PM variable 13 Sep 15, :09 AM Usually 3, some studnets come with complete funding (eg. government) 14 Sep 16, :15 PM 0 15 Sep 17, :33 PM 01/02/ Oct 6, :16 AM 1

23 Which of the following best describes the role of faculty from other schools of the health sciences in your Clinical graduate program? 23.1% (3) Fully Integrated Partially Integrated 38.5% (5) Committee Involvement Only 38.5% (5)

24 Do faculty members in your school serve as directors for CTSA supported core facilities? If yes, please describe what facilities (17 Responses) yes basic science/equipment core NMR/Mass spec facility yes Yes, Genotyping Core Laboratory, Comprehensive Drug Development Program Yes. Faculty members from the School of Pharmacy serve as the directors of the proteomics core and the small molecule biomarker core facilities. No Clinical Research Centers; Core Lab Facilities Yes. Chair of GCRC Advisory Committee No yes, translational technologies director No Yes. Experimental Pharmacology. No Analytical Core Facility Director yes, Clinical Trials Unit in Hospital Pharmacometrics

25 Do faculty members in your school serve as members of executive committees, curriculum committees, or integrated research committees associated with the CTSA? If yes, please describe the role of faculty in this capacity. (16 responses) yes Dean member of internal advisory committee; faculty on a number of committees including educational K30, informatics, clinical trials unit and regulatory Board of Governors, Faculty Governance Committee, Scientific Review Panel (pre IRB), IRB, KL2 Scholar Selection, graduate student advisory committees yes Yes, members from our school on all major CTSA committees Yes. Faculty members and the Dean serve on the exective committee. Faculty members from the School serve on the curriculum committee and chair the Core Curriculum committee. Several faculty members from the School have been appointments to the CTSI. No Fully integratged in all committees listed Two currently: Member of excecutive committee; member of MS in CTS advisory committee Yes, we have faculty serving on the curriculum committee and integrated research commitees Yes, members on steering committee and research education committee Yes, several members are on a pending CTSA application Membership on the Scientific Review Panel for the CTRC Yes, on IT committee and education committee no Yes, executive cmtes, research cmtes Executive and curriculum committees

26 Have faculty in your school contributed significantly to the preparation and submission of a CTSA grant proposal? If yes, please describe these contributions. yes, as above Yes. A number of faculty were involved in all levels of the preparation of the grant. It has not been funded as of this time. Yes, Chris Sorkness is Senior Associate Director of ICTR and was co PI on the CTSA yes Yes, key roles as Core Directors, Steering Committee members, Deans, etc in writing and review of the grant proposal Yes. Faculty from the school wrote significant portions of the original grant submission particularly related to the educational core. No Yes faculty involved in developing CTSA training programs Yes. A faculty member co authored one of the sections. Yes, we were highly involved with the CTSA proposal Yes, to specific sections Yes, one faculty member with a 5 year training grant in infectious diseases/ epidemiology Yes; served on steering committee and several subcommittees Yes Contributions to the Biostatistics, Epidemiology and Research Design program. yes, for the first CTSA one faculty member wrote the educaton proposal and one mostly wrote the IT proposal. The application was not funded, and netiher contributed substantially to the 2nd application Yes, faculty and administrators were very involved in the CTSA proposal yes, co chair Development of training programs

27 Do you believe that the school is an active and critical component to the function or planning of the CTSA grant at your institution? yes Yes Yes yes yes Yes. Yes Yes Yes. Yes In some aspects yes Yes Yes Yes. Not in any substantial way...unfortunately. Yes, but role could still be expanded yes Yes

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