Early Detection Increases Survival Rate For Cancer Patients
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2 Werner von Siemens ( ) Voor de winst op de korte termijn verkoop ik de toekomst niet
3 Innovations keep us strong Milestones across the centuries
4 Spin-ins and spin-outs Siemens Technology Accelerator (STA) Munich Technology-to-Business Center (TTB) Berkeley, Shanghai Siemens Venture Capital 1) Munich, USA, Israel, China, India Seed phase (ideas, patents) Start-up phase Market entry/ expansion Exit (floating/selling) Siemens Venture Capital (SVC) M&A Siemens Technology Accelerator (STA) Siemens Technology-to-Business Center (TTB) Tasks and objectives Driving innovative ideas/technologies for new markets to strengthen the company s power to innovate with an adequate return Generating new business by turning innovative ideas to practical account: Spin-ins and spin-outs: embedded in existing Siemens structures or in the form of a start-up foundation (STA and TTB) Direct participation in external start-up companies and VC funds (SVC) Support and growth through financing and coaching Coupling technology orientation with business orientation Establishing a new culture of innovation and entrepreneurship 1) Siemens Venture Capital has up to now invested in over 150 technology companies and 40 venture capital funds.
5 Networks are the breeding grounds for innovation Universities Research Institutes Key Customers Other Industries Competitors Governmental partners ''Think Tanks'' Start-up / VCs
6 conducts R&D at some 150 locations worldwide Some of the major R&D locations Gothenburg Oslo Pandrup Berlin Brussels Hoffmann Estates Roke Manor Issaquah Auburn Hills Paris Sacramento Chatham Concord Danvers Toulouse Berkeley Princeton Madrid Knoxville Lisbon San José Orlando Zaragoza San Diego Arlington Zurich Austin Guadalajara Milan Vienna Bogotá São Paulo Curitiba Buenos Aires Erlangen Nuremberg Regensburg Munich Helsinki St. Petersburg Moscow Prague Budapest Istanbul Netanya Athens Tel Aviv New Delhi Mumbai Goa Bangalore Pretoria Penang Singapore Asia/Pacific 10% (~3,200) America 24% (~7,300) Europe 25% (~7,600) Changchun Seoul Tokyo Beijing Tianjin Shanghai Taipei Hong Kong Xian Chengdu Nanjing Melbourne Sidney Africa, Near and Middle East, GUS 0.5% (~50) Germany 41% (12,700) 30,800 R&D Employees 1) (FJ 2009) 1) Including 17,000 Software engineers
7 Cooperations with leading research institutions Berkeley Princeton Romsey Germany Moscow Peking Tokyo Shanghai Major strategic cooperations agreements: USA MIT, Boston UC Berkeley Bangalore Further examples of important cooperation partners: Singapore Europe RWTH Aachen TU Berlin TU Munich TU Bergakademie Freiberg University Greifswald DTU Copenhagen China Tongji University, Shanghai Tsinghua University, Beijing University of Calgary Carnegie Mellon University, Pittsburgh Centre de Recherche Informatique de Montreal TU Twente, Groningen, Unimaas, Erasmus Eidgenössische Technische Hochschule Zürich TU Kaiserslautern FAU Erlangen-Nuremberg Fraunhofer Gesellschaft TU Dresden Johannes Kepler University Linz Budapest University of Technology and Economics St. Petersburg University Indian Institute of Technology Bombay GIST Singapore CT locations CT cooperations Graphic: Examples of Siemens CT s research cooperation arrangements. Siemens CT accounts for around 50 percent of Siemens research cooperation arrangements, the others are initiated directly by Siemens Sectors. Over 1,000 new such arrangements are launched each year.
8 Siemens Dutch innovations Top research ontwikkelingen ism met Nederlandse Ziekenhuizen op het gebied van beeldvorming 1988 eerste spiraal CT wereldwijd in Rotterdam (Somatom plus spiraalscanner) 1989 Cum Laude RSNA award voor wetenschappelijk werk aan spiraal CT 1991 Eerste tafel-geintegreerde bediening angiokamer 1993 Siemens introductie Evolution EBT 1994 X-ray tube technologie met extra beam filtering 1995 Siemens introductie High Power Gradient MR Imaging 1999 eerste MDCT in Rotterdam eerste 3 Tesla Mri voor centrum cognitieve Neuro imaging 2002/ MDCT & 64-MDCT 2005 Dedicated 3 Tesla brain Mri 2007 Dual Source Computed Tomography 2010 eerste automated breast volume scanner in s Hertogenbosch
9 Source: Siemens Medical Solutions Disease progression example cancer
10 Early detection has clear financial and clinical benefits Example: Breast cancer Early detection increases survival rate and reduces treatment cost % alive 15 years after diagnosis Treatment cost ($000) 80% % 60% 50% 40% 30% 20% % 20 0% No cancer Stage 0 Stage I Stage II Stage III Stage IV 0 Survival by stage of diagnosis; American Cancer Society, 2008
11 Medical imaging evolutions 80s Mainstream 90s Mainstream 00s Mainstream Next Mainstream X-Ray-based Anatomical Imaging: XR, CT, Ultrasound CT, MR, US Anatomical Imaging Digital XR Anatomical Correlation of Functional Imaging: PET CT, SPECT CT, PET/MR Molecular Diagnostics + Molecular Imaging + Molecular Therapeutics Emerging Emerging Emerging Emerging MR Anatomical Imaging (Soft-Tissue Visualization) Functional Imaging MR, PET MR Spectroscopy (Characterization) Anatomical Registration of Molecular Imaging Molecular Therapeutics & Diagnostics Image-guided Gene Therapy
12 What got us there? Innovation is in our genes. 12 Siemens Healthcare Molecular Imaging
13 Efficient medicine is based on knowledge Understand the patient's disease Diagnosis of a disorder (e.g. infection, cancer, ) Localization of disease (e.g. stenosis, tumor, ) Reveal multi-morbidities Understand the patient s biology Genetic pre-disposition Patient metabolism / immune reactions Molecular specificities of the disease Stratification for treatment Access state-of-the-art data bases Assessment of similar cases Structured outcome analysis Decision support systems Standards of Care Imaging, Diagnostics Molecular applications Healthcare IT
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