Adult Stem Cells A Challenge for the Future

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1 Università di Bologna Alma Mater Studiorum Facoltà di Medicina e Chirurgia Istituto di Ematologia e Oncologia Medica "L. e A. Seràgnoli" Azienda Ospedaliera di Bologna Policlinico S. Orsola Malpighi Adult Stem Cells A Challenge for the Future Presidents Michele Baccarani, Sante Tura Program Bologna, March 21-23, 2004

2 Adult Stem Cells A Challenge for the Future A MULTIDISCIPLINARY PROJECT OF THE UNIVERSITY OF BOLOGNA AND OF S.ORSOLA - MALPIGHI UNIVERSITY HOSPITAL. Departments of Cardiology and Hematology Internal Medicine and Hepatology Internal Medicine and Gastroenterology Clinical Medicine and Biotechnology and Cancer Research Center G.Prodi SCIENTIFIC SECRETARIAT Roberto M. Lemoli INSTITUTE OF HEMATOLOGY AND MEDICAL ONCOLOGY L e A. SERÀGNOLI - S.ORSOLA - MALPIGHI UNIVERSITY HOSPITAL VIA MASSARENTI, BOLOGNA, ITALY TEL FAX rmlemoli@med.unibo.it ORGANIZING SECRETARIAT Studio E. R. Congressi - Gruppo Triumph VIA MARCONI BOLOGNA. ITALY TEL FAX a.marchioni@gruppotriumph.it AUSPICES SIE (Società Italiana di Ematologia) SIES (Società Italiana di Ematologia Sperimentale) BOLOGNAIL (Associazione Italiana Leucemie - Linfomi) 2 supported by an unrestricted grant from Dompé-Biotec and Novartis Farma

3 Adult Stem Cells A Challenge for the Future Faculty Malcom R. Alison Sergio Amadori Piero Anversa Michele Baccarani Andrea Bacigalupo Yann Barrandon Agostino Baruzzi Mauro Bernardi Francesco Bertolini Francesco Bianchi Luigi Bolondi Edoardo Boncinelli Angelo Branzi Ranieri Cancedda Carmelo Carlo-Stella Lucio Cocco Roberto Corinaldesi Michele De Luca Sergio Dompé Giuliana Ferrari Sergio Ferrari Walter Grigioni Martin Korbling Diane Krause Maria Paola Landini Tsvee Lapidot Roberto M. Lemoli Gianvito Martino Fulvio Mavilio Maurizio Muraca Vittorio Rizzoli Enrico Roda Saul Sharkis Girolamo Sirchia Christof Stamm Sergio Stefoni Sante Tura London, England Roma, Italy New York, USA Genova, Italy Lausanne, Switzerland Milano, Italy Trieste, Italy Genova, Italy Milano, Italy Venezia, Italy Milano, Italy Milano, Italy Modena, Italy Houston, USA New Haven, USA Rehovot, Israel Milano, Italy Modena, Italy Padova, Italy Parma, Italy Baltimore, USA Roma, Italy Rostock, Germany 3

4 Adult Stem Cells A Challenge for the Future March 21, p.m. University Main Hall, S.Lucia Welcome Lecture: Regenerative medicine: From cells novel therapeutic approaches and drugs S. Dompé Introduced by M.P. Landini Round Table Discussion: Adult and embryonic stem cells Chairmen M. Baccarani, G. Sirchia, S. Tura Discussants P. Anversa E. Boncinelli S. Dompé R.M. Lemoli 7.00 p.m. Cocktail 4

5 Adult Stem Cells A Challenge for the Future March 22, 2004 Royal Hotel Carlton Session I: Chairmen: Adult stem cell biology M. Bernardi, V. Rizzoli 8.30 a.m a.m. Biology and therapeutic use of mesenchimal stem cells (C. Carlo-Stella) 9.00 a.m a.m. Bone marrow stem cell biology via molecular profiling (S. Ferrari) 9.30 a.m a.m. Functional and kinetic characterization of hematopoietic stem cells (R.M. Lemoli) a.m a.m. Genetic modification of hematopoietic stem cells: a challenge for the present (F. Mavilio) a.m a.m. Coffee break Session II: Chairmen: Adult stem cell biology S. Amadori, R. Corinaldesi a.m a.m. Epithelial stem cells (Y. Barrandon) a.m a.m. Regeneration of vascular endothelium by adult stem cells (F. Bertolini) a.m a.m. Cardiac stem cells and the infarcted heart (P. Anversa) a.m p.m. Hematopoietic stem cell transplantation: A paradigma of stem cell plasticity (A. Bacigalupo) 1.00 p.m p.m Lunch break 2.00 p.m p.m. Selected Oral Communications Chairmen: F. Bianchi, S. Stefoni 5

6 Adult Stem Cells A Challenge for the Future March 22, 2004 Royal Hotel Carlton Session III: Chairmen Animal models of differentiation L. Bolondi, W. Grigioni 4.00 p.m p.m. Plasticity of a pure population of hematopoietic stem cells into multiple epithelial tissues (S. Sharkis) 4.30 p.m p.m. Bone marrow stem cells as progenitors of liver epithelium? (M.R. Alison) 5.00 p.m p.m. Migration and engraftment of hematopoietic stem cells into nonhematopoietic tissues is mediated by stress signals (T. Lapidot) 5.30 p.m p.m. The myogenic potential of hematopoietic cells (G. Ferrari) 6

7 Adult Stem Cells A Challenge for the Future March 23, 2004 Royal Hotel Carlton Session IV: Chairmen Therapeutic perspectives of adult stem cells A. Branzi, E. Roda 8.30 a.m a.m. Potential role of circulating adult stem cells (M. Korbling) 9.00 a.m a.m. Heart (C. Stamm) 9.30 a.m a.m. Liver (M. Muraca) a.m a.m. Coffee break Chairmen A. Baruzzi, L. Cocco a.m a.m. Central Nervous System (G. Martino) a.m a.m. Skin (M. De Luca) a.m a.m. Bone and cartilage (R. Cancedda) a.m a.m. Somatic stem cell plasticity? (D. Krause) a.m. Concluding remarks (M. Baccarani) 7

8 General Information General Information MEETING VENUES March 21, 2004 AULA MAGNA S.LUCIA Via Castiglione Bologna March 22-23, 2004 ROYAL HOTEL CARLTON Via Montebello, Bologna Tel Fax HOW TO GET TO AULA MAGNA S.LUCIA Walking from downtown or by taxi HOW TO GET TO ROYAL HOTEL CARLTON CAR From the motorway, turn into the ring road ( Tangenziale ) Exit 7 ( Fiera ) Towards the center of the city and the railway station TAXI From the airport (about 30 minutes) BUS Bus 91 or Aerobus from the airport to the railway station TRAIN From the railway station 10 minutes on foot OFFICIAL LANGUAGE March 21, Italian - March 22-23, English 8

9 General Information General Information ECM Application for ECM credits has been made. ATTENDANCE CERTIFICATE A certificate will be given to all participants at the end of the Meeting. ATTENDANCE AND REGISTRATION March 21 - University Main Hall, S.Lucia Attendance is free - Preregistration is required March Royal Hotel Carlton Attendance is free - Preregistration is required Please return the pre-registration Form to the Organizing Secretariat Studio E.R. Congressi - Gruppo Triumph Via Marconi, Phone Fax a.marchioni@gruppotriumph.it TRAVEL AGENCY Bononia Viaggi s.r.l. Piazza dei Martiri, Bologna Phone Fax

10 Technical Information Technical Information SPEAKERS CENTER Only Computer Videoprojection will be available (Power Point System). We kindly request you to prepare your presentation in PC format and provide us with either a CD, floppy disk or memory stick at least one hour before the beginning of the session. BADGE All preregistered participants and speakers will be given a badge which must be worn throughout the meeting. ORAL COMUNICATIONS A plenary session is devoted to oral communications. Eight communications will be selected among those received. All received abstracts will be published on a supplement of "Haematologica" journal. Abstracts should be submitted by to the secretariat Studio E.R. Congressi; a.marchioni@gruppotriumph.it within March 1st, 2004 The abstracts should be written in English and typed in Word program. CHANGES Parts of the program may be changed by the Scientific Committee or by the Organizing Secretariat if necessary for scientific or technical reasons. 10

11 Registration Form Registration Form Please, return this form to: STUDIO E.R. CONGRESSI - GRUPPO TRIUMPH Via Marconi, Bologna - Italy Phone Fax ercongressi@gruppotriumph.it Last Name First Name Position title Institution Address City State/Province Zip Country Telephone Fax 11

12 Adult Stem Cells A Challenge for the Future

13 Hotel Reservation Form Hotel Reservation Form BONONIA VIAGGI - BUSINESS, TRAVEL INCENTIVE Piazza dei Martiri, Bologna - Italy Phone Fax Last Name First Name Position title Institution Address City Zip Telephone State/Province Country Fax FOR THE INVOICE: Last Name First Name Address City Zip State/Province Country Vat Number ( P. IVA) Tax Payer s number (COD. FISCALE) Name of the accompanying person 13

14 Hotel Reservation Form Hotel Reservation Form HOTEL CATEGORIES AND PRICES Category Single Double Single Use 4 STARS 3 STARS MIN. Euro 115 Euro 98 MAX. Euro 132 Euro 110 MIN. Euro 130 Euro 130 MAX. Euro 160 Euro 150 Double MIN. Euro 145 Euro 145 MAX. Euro 190 Euro 170 These prices are per night and per room and include bed, breakfast and taxes. Reservation fee, Euro 15,00 per room. HOTEL RESERVATION 4 stars 3 stars Single Double Double Single Use DATE OF ARRIVAL In case of double room, indicate the name of your room-mate DATE OF DEPARTURE PAYMENT I enclose Eurocheque or Foreign Cheque of Euro Number Bank made out to Bononia Viaggi s.r.l. Bank transfer made out to Bononia Viaggi s.r.l. - Account n 9000/2 - CARISBO Filiale San Giuseppe - Via Saragozza 87 - Bologna, BO - Italy - ABI CAB Credit Card Number Owner Expiry date Date of birth Visa Mastercard Diners American Express Hotel Reservation can only be accepted and confirmed when the form and the confirmatory deposit the price of one night per room in the selected hotel category (plus Euro 15,00 for agency rights) have been received by Bononia Viaggi. Date Signature

15 Information on Law n. 675 Information on Law n. 675 a. Your personal data written in this form together with spoken data given later during the congresses organized or promoted by us will be employed by Studio E.R. Congressi S.r.l. for managing, accounting, statistical, commercial, marketing and/or promoting purposes and this by processing, comparing, divulging or employing these very data. b. To be registered in the congresses we organize, you are obliged to give your data. c. Your data can be given the organizers of the congress, the companies sponsoring the event as well as to other companies, authorities, consortia or associations that could divulge these data to their members, users and other related people within the limits of their institutional purposes. The only objective is to inform the person concerned about the existence of similar initiatives or to supply him with other information that could be deemed interesting. d. Furthermore, the above mentioned data can be given/divulged to companies, authorities, consortia or associations working in Italy or in the EC countries having the same objective as stated in the previous paragraph. e. Data will be processed by appropriate devices ensuring their security and confidentiality. Data could be also processed by automatic machines employed to process, store and transmit the very data. As to the above mentioned data processig, Studio E.R. Congressi S.r.l. must without delay: a. confirm to the person concerned the existence of his/her personal data, even if they have not been stored yet, purvey these data and their origin in a form which is readily comprehensible, specify the logic the data processing is based on. Unless for justified reasons, this request can be submitted again at least 90 days after the first submission; b. delete, render anonymous or stop the flowing of those data - all data related to the person concerned processed in violation of the law; c. update, rectify or, upon request of the person concerned, complete the integration of these data; d. certify that all companies, associations etc. provided with these data have been informed of what is specified in the paragraphs b) and c) - unless the means employed to inform them are disproportionate. The person concerned has the right to know - consulting the register specified in the art. 31, sub-section 18, letter a) of the law n. 675, Dec. 31, the existence of data processing; he/she can partially or entirely oppose, for legitimate reasons, the processing of his/her data, even if these data are relevant to the objective of data collection. Furthermore he can prevent his/her data from being used for commercial purposes, market surveys, advertisement for direct selling or interactive commercials.

16 ORGANIZING SECRETARIAT Studio ER Congressi - Gruppo Triumph Via Marconi 36, Bologna/Italy Tel Fax a.marchioni@gruppotriumph.it

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