Cutting-edge science means everything to the family it helps.

Transcription

1 Cutting-edge science means everything to the family it helps. We re seeing stem cells introduce new medical options to families. In fact, newborn stem cells saved with CBR are now being accessed by a new family for current and experimental treatments averaging every week. And as the science develops, so do the possibilities. Are we there yet for some conditions? Yes. Are we going even further? Yes. The future starts with each family. More families, more uses & research Reasons to keep your baby s stem c e l ls

2 REGENERATIVE MEDICINE Clinical Trials REGENERATIVE MEDICINE Stem cells have demonstrated the potential to help conditions that have no cure today by regenerating damaged tissue and restoring lost function after an injury or illness. CLINICAL TRIALS CBR-PARTNERED CLINICAL TRIALS CBR is advancing potential stem cell uses by partnering with leading research institutions to establish FDA-regulated clinical trials in regenerative medicine. These ground-breaking trials only use cord blood stem cells processed by Cord Blood Registry as a way of ensuring consistent quality. These trials are currently underway, and results are not yet published. CLINICAL TRIALS FDA-regulated clinical trials determine the safety and efficacy of a new therapy. These must be completed prior to being approved for widespread use for treatment. Type1 Diabetes clinical trial has concluded. RELEASE MEDICAL CONDITION RELATIONSHIP AGE GENDER STORAGE TI ME 2014 Acquired Hearing Loss Self <1 F 8 CBR-Partnered Florida Hospital for Children - Orlando, FL 2014 Autism Self 4 M 50 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2014 Autism Self 5 F 70 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2014 Autism Self 3 M 45 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2014 Autism Self 5 M 64 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2014 Autism Self 5 M 65 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2014 Acquired Hearing Loss Self 6 F 84 CBR-Partnered Florida Hospital for Children - Orlando, FL 2013 Cerebral Palsy Self 3 M 44 CBR-Partnered Georgia Regents University - Augusta, GA 2013 Autism Self 3 M 45 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Acquired Hearing Loss Self 1 F 13 CBR-Partnered Florida Hospital for Children - Orlando, FL 2013 Autism Self 5 M 66 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Autism Self 3 M 38 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Acquired Hearing Loss Self 5 F 68 CBR-Partnered Florida Hospital for Children - Orlando, FL 2013 Autism Self 3 M 40 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Cerebral Palsy Self 1 F 17 CBR-Partnered Georgia Regents University - Augusta, GA 2013 Autism Self 6 M 78 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Cerebral Palsy Self 1 M 19 Clinical Trial Duke University - Durham, NC 2013 Autism Self 3 M 37 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Cerebral Palsy Self 2 M 35 Clinical Trial Duke University - Durham, NC 2013 Autism Self 5 M 65 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Cerebral Palsy Self 1 M 15 Clinical Trial Duke University - Durham, NC 2013 Autism Self 3 M 45 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Autism Self 5 F 69 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Autism Self 6 M 74 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Cerebral Palsy Self 5 M 63 Clinical Trial Duke University - Durham, NC 2013 Autism Self 4 M 58 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Cerebral Palsy Self 1 F 13 Clinical Trial Duke University - Durham, NC 2013 Cerebral Palsy Self 7 F 93 CBR-Partnered Georgia Regents University - Augusta, GA 2013 Autism Self 5 M 64 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Cerebral Palsy Self 3 M 43 Clinical Trial Duke University - Durham, NC 2013 Autism Self 4 M 49 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Autism Self 3 M 47 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Autism Self 4 M 51 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Autism Self 4 M 57 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Cerebral Palsy Identical Twin 2 F 25 Clinical Trial Duke University - Durham, NC 2013 Autism Self 2 M 31 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Cerebral Palsy Self 2 M 29 Clinical Trial Duke University - Durham, NC 2013 Cerebral Palsy Self 4 F 38 CBR-Partnered/NPP Georgia Regents University - Augusta, GA 2013 Cerebral Palsy Self 2 F 27 CBR-Partnered Duke University - Durham, NC 2013 Cerebral Palsy Self 11 M 143 CBR-Partnered Georgia Regents University - Augusta, GA 2013 Autism Self 3 M 45 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2013 Autism Self 3 M 36 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2012 Autism Self 4 F 59 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2012 Autism Self 4 M 54 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2012 Autism Self 4 M 56 CBR-Partnered Sutter Memorial Hospital - Sacramento, CA 2012 Cerebral Palsy Self 2 M 30 CBR-Partnered/NPP Georgia Regents University - Augusta, GA 2012 Cerebral Palsy Self 1 M 22 CBR-Partnered Georgia Regents University - Augusta, GA 2012 Cerebral Palsy Self 2 M 24 CBR-Partnered/NPP Georgia Regents University - Augusta, GA 2012 Cerebral Palsy Self 1 F 23 Clinical Trial Duke University - Durham, NC 2012 Cerebral Palsy Self 1 M 22 Clinical Trial Duke University - Durham, NC 2012 Cerebral Palsy Self 1 M 19 Clinical Trial Duke University - Durham, NC 2012 Cerebral Palsy Self 5 F 64 CBR-Partnered Georgia Regents University - Augusta, GA 2012 Acquired Hearing Loss Self 1 F 19 CBR-Partnered Memorial Hermann Texas - Houston, TX

3 REGENERATIVE MEDICINE Clinical Trials RELEASE MEDICAL CONDITION RELATIONSHIP AGE GENDER STORAGE TI ME 2011 Cerebral Palsy Self 2 F 25 Clinical Trial/NPP Duke University - Durham, NC 2011 Cerebral Palsy Self 1 M 13 Clinical Trial Duke University - Durham, NC 2011 Cerebral Palsy Self 1 M 17 Clinical Trial Duke University - Durham, NC 2011 Cerebral Palsy Self 2 M 34 Clinical Trial Duke University - Durham, NC 2011 Cerebral Palsy Self 1 M 14 Clinical Trial Duke University - Durham, NC 2011 Cerebral Palsy Self 2 F 32 CBR-Partnered Georgia Regents University - Augusta, GA 2011 Cerebral Palsy Self 3 F 46 Clinical Trial Duke University - Durham, NC 2011 Cerebral Palsy Self 1 M 21 CBR-Partnered Georgia Regents University - Augusta, GA 2011 Cerebral Palsy Self 5 M 65 CBR-Partnered Georgia Regents University - Augusta, GA 2011 Cerebral Palsy Self 1 M 18 Clinical Trial Duke University - Durham, NC 2011 Cerebral Palsy Self 3 M 45 Clinical Trial Duke University - Durham, NC 2011 Cerebral Palsy Self 2 F 25 CBR-Partnered Georgia Regents University - Augusta, GA 2010 Type I Diabetes Self 2 M 27 Clinical Trial Shands Hospital, University of Florida - Gainesville, FL 2010 Cerebral Palsy Self 1 M 17 Clinical Trial Duke University - Durham, NC 2010 Cerebral Palsy Self 1 M 21 Clinical Trial Duke University - Durham, NC 2010 Type I Diabetes Self 11 M 138 Clinical Trial Shands Hospital, University of Florida - Gainesville, FL 2010 Cerebral Palsy Self 2 F 25 CBR-Partnered Georgia Regents University - Augusta, GA 2010 Cerebral Palsy Self 3 M 38 CBR-Partnered Georgia Regents University - Augusta, GA 2010 Cerebral Palsy Self 2 F 28 CBR-Partnered Georgia Regents University - Augusta, GA 2010 Type I Diabetes Self 1 M 19 Clinical Trial Shands Hospital, University of Florida - Gainesville, FL 2008 Type I Diabetes Self 6 F 78 Clinical Trial Shands Hospital, University of Florida - Gainesville, FL 2008 Type I Diabetes Self 3 F 43 Clinical Trial Shands Hospital, University of Florida - Gainesville, FL 2008 Type I Diabetes Self 5 F 61 Clinical Trial Shands Hospital, University of Florida - Gainesville, FL 2008 Type I Diabetes Self 3 M 37 Clinical Trial Shands Hospital, University of Florida - Gainesville, FL 2008 Type I Diabetes Self 8 M 105 Clinical Trial Shands Hospital, University of Florida - Gainesville, FL 2007 Type I Diabetes Self 7 M 95 Clinical Trial Shands Hospital, University of Florida - Gainesville, FL 2007 Type I Diabetes Self 2 F 24 Clinical Trial Shands Hospital, University of Florida - Gainesville, FL 2007 Type I Diabetes Self 2 M 27 Clinical Trial Shands Hospital, University of Florida - Gainesville, FL REGENERATIVE MEDICINE Other Experimental Therapies OTHER EXPERIMENTAL THERAPIES OTHER EXPERIMENTAL THERAPIES Some cord blood stem cell uses are currently being performed outside of an FDA-regulated clinical trial. NEWBORN POSSI BI LITI ES (NPP) CBR s program identifies individuals who may benefit from newborn stem cells now or in the near future. The newborn s stem cells are stored free for 5 years for qualified families. RELEASE MEDICAL CONDITION RELATIONSHIP AGE GENDER STORAGE TI ME 2014 Hypoxic Ischemic Encephalopathy Self 5 F 60 Family Duke University - Durham, NC 2014 Cerebral Palsy Self 2 M 32 Family Duke University - Durham, NC 2014 Hypoxic Ischemic Encephalopathy Self <1 F <2 Family Duke University - Durham, NC 2014 Cerebral Palsy Self 5 F 67 Family Duke University - Durham, NC 2014 In Utero Stroke Self 1 M 19 Family Duke University - Durham, NC 2014 Cerebral Palsy Self 2 F 28 Family Duke University - Durham, NC 2014 Hypoxic Ischemic Encephalopathy Self 3 F 42 Family Duke University - Durham, NC 2014 Expressive Language Disorder Self 2 M 32 Family Duke University - Durham, NC 2014 Developmental Delay Self <1 M 6 Family Duke University - Durham, NC 2014 Hydrocephalus Self <1 M <2 Family Duke University - Durham, NC 2013 Hydrocephalus Self <1 F <2 Family Duke University - Durham, NC 2013 Apraxia Self 3 M 46 Family Duke University - Durham, NC 2013 Encephalopathy Self 3 F 38 Family Duke University - Durham, NC 2013 Developmental Delay Self 3 M 42 Family Duke University - Durham, NC 2013 Cerebral Palsy Self 4 M 59 Family Duke University - Durham, NC 2013 Acute Disseminated Encephalomyelitis Self 6 M 74 Family Duke University - Durham, NC 2013 Hypoxic Ischemic Encephalopathy Self <1 M <1 NPP Duke University - Durham, NC 2013 Mixed Tone Cerebral Palsy Self 15 M 187 Family Duke University - Durham, NC 2013 Global Developmental Delay Self 4 F 52 Family Duke University - Durham, NC 2013 Developmental Delay Self 1 F 13 Family Duke University - Durham, NC 2012 Anoxic Brain Injury Self 5 F 66 Family Duke University - Durham, NC 2012 Hydrocephalus Self <1 M 6 NPP Duke University - Durham, NC 2012 Periventricular Leukomalacia Self 1 M 18 Family Duke University - Durham, NC 2012 Developmental Delay Self 6 M 77 Family Duke University - Durham, NC 2012 Cerebral Palsy Self 1 M 15 Family Duke University - Durham, NC

4 REGENERATIVE MEDICINE Other Experimental Therapies RELEASE MEDICAL CONDITION RELATIONSHIP AGE 2012 Fetal Brain Injury Self <1 F 1 Family Duke University - Durham, NC 2012 Near Drowning Self 7 F 90 Family Duke University - Durham, NC 2012 Cerebral Palsy Self 2 M 26 Family Duke University - Durham, NC 2012 Cerebral Palsy Self <1 M 7 Family Duke University - Durham, NC 2012 Cerebral Palsy Self 6 M 72 Family Duke University - Durham, NC 2012 Hydrocephalus Self <1 F 8 NPP Duke University - Durham, NC 2012 Hemiplegia Self 2 M 35 Family Duke University - Durham, NC 2012 Cerebral Palsy Self 2 F 30 Family Duke University - Durham, NC 2012 Developmental Delay Self 4 M 59 Family Duke University - Durham, NC 2012 Cerebral Palsy Self 4 M 56 Family Duke University - Durham, NC 2012 Apraxia Self 5 F 69 Family Duke University - Durham, NC 2011 Apraxia Self 3 F 39 Family Duke University - Durham, NC 2011 Traumatic Brain Injury Self 7 M 90 Family U.C. Davis Medical Center - Sacramento, CA 2011 Developmental Delay Self 1 F 23 Family Duke University - Durham, NC 2011 Cerebral Palsy Self 1 M 15 Family Duke University - Durham, NC 2011 Traumatic Brain Injury Self 5 F 60 Family Duke University - Durham, NC 2011 Periventricular Leukomalacia; Mild Cerebral Palsy GENDER STORAGE TI ME Self 3 F 36 Family Duke University - Durham, NC 2011 Apraxia Self 2 M 29 Family Duke University - Durham, NC 2011 Cerebral Palsy Self 3 F 46 Family Duke University - Durham, NC 2011 Hypoxic Ischemic Encephalopathy Self <1 M 9 Family Duke University - Durham, NC 2011 Cerebral Palsy Self 2 M 32 Family Duke University - Durham, NC 2011 Developmental Delay Self 4 M 53 Family Duke University - Durham, NC 2011 Developmental Delay Self 3 M 37 Family Duke University - Durham, NC 2011 Hydrocephalus Self <1 F 10 Family Duke University - Durham, NC 2011 Developmental Delay Self 2 F 25 Family Duke University - Durham, NC 2011 Hypotonia Self 6 M 75 Family Duke University - Durham, NC 2011 Cerebral Palsy Self 2 M 28 Family Duke University - Durham, NC 2010 Hydrocephalus Self 1 M 5 Family Duke University - Durham, NC 2010 Autologous Therapy Self 4 F 49 Family Hospital Angeles Tijuana - Tijuana, Mexico 2010 In Utero Stroke Self 1 F 14 Family Duke University - Durham, NC 2010 Developmental Delay Self 2 M 32 Family Duke University - Durham, NC 2010 Periventricular Leukomalacia Self 1 M 13 Family Duke University - Durham, NC 2010 Developmental Delay Self <1 F 10 Family Duke University - Durham, NC 2010 Cerebral Palsy Self 7 F 87 Family Duke University - Durham, NC 2010 Cerebral Palsy Self 1 M 19 Family Duke University - Durham, NC 2010 Hemiplegia Self 1 M 16 Family Duke University - Durham, NC 2010 Hypotonia Self 1 M 20 Family Duke University - Durham, NC 2010 Hypoxic-Ischemic Encephalopathy Self 1 M 13 NPP Duke University - Durham, NC 2010 Cerebral Palsy Self 1 M 19 Family Duke University - Durham, NC 2010 Spastic Diplegia Self 5 F 64 Family Duke University - Durham, NC 2010 Hemiparesis Self 1 M 18 Family Duke University - Durham, NC 2010 Apraxia Self 5 F 61 Family Duke University - Durham, NC 2010 Developmental Delay Self 5 M 63 Family Duke University - Durham, NC 2010 Cerebral Palsy Self 6 M 83 Family Duke University - Durham, NC 2010 Cerebral Palsy Self 1 M 21 Family Duke University - Durham, NC 2010 Apraxia Self 3 F 42 Family Duke University - Durham, NC 2009 Static Encephalopathy Self 1 F 22 Family Duke University - Durham, NC 2009 Hypoxic-Ischemic Encephalopathy Self 1 M 1 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 3 M 47 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 4 M 50 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 3 M 45 Family Duke University - Durham, NC 2009 Periventricular Leukomalacia Self 1 M 16 Family Duke University - Durham, NC 2009 Stroke Self 1 F 19 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 9 M 113 Family Duke University - Durham, NC 2009 Periventricular Leukomalacia Self 1 F 1 Family Duke University - Durham, NC 2009 In-Utero Stroke Self 1 M 20 Family Duke University - Durham, NC 2009 Brain Injury Self 4 F 49 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 1 M 16 Family Duke University - Durham, NC

5 REGENERATIVE MEDICINE Other Experimental Therapies RELEASE MEDICAL CONDITION RELATIONSHIP AGE GENDER STORAGE TI ME 2009 Cerebral Palsy Self 2 M 32 Family Duke University - Durham, NC 2009 Periventricular Leukomalacia Self 1 F 12 Family Duke University - Durham, NC 2009 Cerebral Palsy Self <1 F 10 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 3 F 38 Family Duke University - Durham, NC 2009 Anoxic Brain Injury Self 2 F 33 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 1 F 20 Family Duke University - Durham, NC 2009 Autologous Therapy Self <1 M <1 Family University Medical Center - Tucson, AZ 2009 Cerebral Palsy Self 2 M 33 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 7 F 88 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 1 M 15 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 2 F 22 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 3 M 37 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 4 M 53 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 1 F 12 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 1 M 17 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 2 M 27 Family Duke University - Durham, NC 2009 Traumatic Brain Injury Self 5 F 67 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 4 M 56 Family Duke University - Durham, NC 2009 Cerebral Palsy Self 3 M 40 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 9 M 115 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 2 M 32 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 2 M 27 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 7 F 91 Family Duke University - Durham, NC 2008 Hydrocephalus Self <1 F 4 Family Duke University - Durham, NC 2008 Hydrocephalus Self <1 F 1 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 2 M 32 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 4 F 58 Family Duke University - Durham, NC 2008 Head Injury Self 3 F 41 Family Duke University - Durham, NC 2008 Birth Hypoxia Self <1 M 2 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 4 F 50 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 1 M 12 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 3 F 37 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 1 F 18 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 2 F 33 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 2 M 35 Family Duke University - Durham, NC 2008 Hypoxic-Ischemic Encephalopathy Self <1 F <1 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 3 F 45 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 3 M 42 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 2 F 24 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 2 M 24 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 5 F 61 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 8 F 98 Family Duke University - Durham, NC 2008 Encephalitis Self 2 M 24 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 3 M 39 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 1 M 20 Family Duke University - Durham, NC 2008 Non-specific Brain Injury Self 2 M 34 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 1 M 22 Family Duke University - Durham, NC 2008 Cerebral Palsy Self 4 F 51 Family Duke University - Durham, NC 2007 Cerebral Palsy Self 1 M 20 Family Duke University - Durham, NC 2007 Cerebral Palsy Self 2 F 32 Family Duke University - Durham, NC 2007 Cerebral Palsy Self 2 M 36 Family Duke University - Durham, NC 2007 Cerebral Palsy Self <1 M 7 Family Duke University - Durham, NC 2007 Cerebral Palsy Self 1 M 19 Family Duke University - Durham, NC 2007 Cerebral Palsy Self <1 F 10 Family Duke University - Durham, NC 2007 Rare Immune Disorder Self 5 M 70 Family Children s Memorial Hospital Chicago, IL 2006 Cerebral Palsy Self 3 F 43 Family Duke University - Durham, NC 2006 Cerebral Palsy Self 3 M 40 Family Duke University - Durham, NC 2005 Cerebral Palsy Self 2 M 35 Family Duke University - Durham, NC 2005 Traumatic Brain Injury Self 1 F 19 Family Duke University - Durham, NC 2005 Anoxic Brain Injury Self <1 F 5 Family Duke University - Durham, NC

6 TRANSPLANT MEDICINE TRANSPLANT MEDICINE Stem cells are being used to regenerate healthy blood and immune systems after being damaged by diseases like leukemia and sickle cell anemia. FAMILY CBR stores your child s unique stem cells for potential use by a member of your own family. NEWBORN POSSIBILITIES (NPP) This program is offered when a relative of the baby is diagnosed with a condition that is treatable with stem cells and is identified with an immediate need for a stem cell transplant. The newborn s stem cells are stored free for 5 years for qualified families. RELEASE MEDICAL CONDITION RELATIONSHIP AGE GENDER STORAGE TI ME 2013 Aplastic Anemia Self 9 F 118 Family Riley Hospital for Children - Indianapolis, IN 2013 Diamond Blackfan Anemia Sibling 4 F 16 NPP Memorial Sloan Kettering Cancer Center - New York, NY 2013 Beta Thalassemia Major Sibling 10 M 5 NPP Johns Hopkins Hospital - Baltimore, MD 2013 Acute Lymphocytic Leukemia Sibling 5 F 31 NPP Nebraska Medical Center - Omaha, NE 2013 Acute Lymphocytic Leukemia Sibling 7 M 43 NPP Texas Children s Hospital - Houston, TX 2012 Sickle Cell Disease Sibling 4 F 13 NPP Baylor University Medical Center - Dallas, TX 2012 Hemophagocytic Lymphohistiocytosis Sibling <1 F 55 NPP Children s Hospital at Montefiore - Bronx, NY 2012 Diamond Blackfan Anemia Sibling 6 M 32 NPP UCSF Medical Center - San Francisco, CA 2012 Aplastic Anemia Sibling 3 F 6 NPP Children s Healthcare Atlanta - Atlanta, GA 2012 Chronic Granulomotous Disease Sibling 6 F 40 Family Children s National Medical Center - Washington, DC 2012 Hurler Syndrome Sibling 1 F 66 Family Univ. of Minnesota Amplatz Children s Hospital - Minneapolis, MN 2011 Acute Promyelocytic Leukemia Sibling 5 F 5 NPP Children s Healthcare of Atlanta - Atlanta, GA 2011 Aplastic Anemia Self 3 M 41 Family Children s Hospital Los Angeles - Los Angeles, CA 2011 Beta Thalassemia Major Sibling 7 M 26 NPP Memorial Sloan Kettering Cancer Center - New York, NY 2011 Sickle Cell Disease Sibling 7 F 27 NPP Cook Children s Medical Center - Fort Worth, TX 2011 Sickle Cell Disease Sibling 10 M 15 NPP Tulane University Hospital and Clinic - New Orleans, LA 2011 Acute Lymphocytic Leukemia Sibling 1 M 46 Family Westchester Medical Ctr, Maria Fareri Children s Hospital - Valhalla, NY 2011 Sickle Cell Disease Sibling 4 F 20 NPP All Children s Hospital - St. Petersburg, FL 2011 Acute Myelogenous Leukemia Sibling 14 F 7 Family Shanghai Daopei Hospital - Shanghai, China 2011 Acute Lymphocytic Leukemia Sibling 7 F 5 NPP UHCMC Rainbow Babies & Children Hospitals - Cleveland, OH 2010 Acute Lymphocytic Leukemia Sibling 9 M 26 Family Cook Children s Medical Center - Fort Worth, TX 2010 Sickle Cell Disease Sibling 5 M 8 NPP Hackensack University Medical Center - Hackensack, NJ 2010 Sickle Cell Disease Sibling 2 F 4 NPP Cook Children s Medical Center - Fort Worth, TX 2009 Beta Thalassemia Major Sibling 8 M 15 NPP Texas Children s Hospital - Houston, TX 2009 Beta Thalassemia Major Sibling 3 M 14 NPP Cook Children s Medical Center - Fort Worth, TX 2008 Wiskott-Aldrich Syndrome Sibling 2 M 34 Family Washington Hospital Center - Washington DC 2008 Sickle Cell Disease Sibling 7 F 62 NPP Methodist Children s Hospital - San Antonio, TX 2008 Acute Myelogenous Leukemia Sibling 4 M 1 NPP University Medical Center - Tucson AZ 2008 Acute Myelogenous Leukemia Sibling <1 F 35 Family UCSF Medical Center - San Francisco, CA 2008 Acute Lymphocytic Leukemia Sibling 6 F 1 NPP Children s Hospital of Wisconsin - Milwaukee, WI 2008 Acute Myelogenous Leukemia Sibling 3 F 15 Family All Children s Hospital - St. Petersburg, FL 2008 Acute Lymphocytic Leukemia Sibling 1 M 3 NPP University Medical Center - Tucson, AZ 2007 Acute Lymphocytic Leukemia Sibling 7 M 48 NPP Shands Hospital, University of Florida - Gainesville, FL 2007 Acute Myelogenous Leukemia Sibling 2 M 11 NPP Children s Hospital of Boston - Boston, MA 2007 Wolman Disease Sibling <1 F 27 Family Children s Hospital Los Angeles - Los Angeles, CA 2007 Acute Myelogenous Leukemia Sibling 2 M 1 NPP Westchester Medical Center - Valhalla, NY 2006 Diamond Blackfan Anemia Sibling 10 M 24 NPP Schneider Children s Hospital - New Hyde Park, NY 2006 Aplastic Anemia Self 9 F 115 Family City of Hope - Duarte, CA 2006 Acute Myelogenous Leukemia Sibling 1 M 3 NPP All Children s Hospital - St. Petersburg, FL 2006 Aplastic Anemia Self 4 F 58 Family City of Hope - Duarte, CA 2005 Aplastic Anemia Sibling 5 M 24 NPP Children s Hospital of Wisconsin - Milwaukee WI 2005 Beta Thalassemia Major Sibling <1 F 44 Family UCLA/Mattel Children s Hospital - Los Angeles, CA 2004 Aplastic Anemia Sibling 2 M 7 NPP UC Davis Medical Center - Sacramento, CA 2004 Aplastic Anemia Self 3 F 36 Family Children s Hospital Seattle - Seattle, WA 2004 Acute Lymphocytic Leukemia Sibling 3 M 18 NPP Shands Hospital, University of Florida - Gainesville, FL 2004 Fanconi Anemia Sibling 11 M 15 NPP Children s Hospital San Diego - San Diego CA 2004 Acute Lymphocytic Leukemia Sibling 8 F 27 NPP University Medical Center - Tucson AZ 2004 Acute Lymphocytic Leukemia Sibling 5 M 2 NPP Cook Children s Medical Center - Fort Worth, TX 2004 X-linked Hyper IGM Syndrome Sibling 3 M 7 NPP Children s Memorial Hospital - Chicago, IL 2003 Acute Lymphocytic Leukemia Sibling 5 F 5 NPP Hackensack University Medical Center - Hackensack, NJ 2003 Acute Lymphocytic Leukemia Sibling 6 F 35 NPP Vanderbilt Medical Center - Nashville, TN 2002 Beta Thalassemia Major Sibling 7 M 17 NPP University of Michigan - Ann Arbor, MI 2002 Acute Lymphocytic Leukemia Sibling 4 F 10 NPP Children s Hospital Los Angeles - Los Angeles, CA 2002 Acute Biphenotypic Leukemia Sibling 11 F 2 NPP UCLA / Mattel Children s Hospital - Los Angeles, CA

7 TRANSPLANT MEDICINE RELEASE MEDICAL CONDITION RELATIONSHIP AGE GENDER STORAGE TI ME 2002 Acute Lymphocytic Leukemia Sibling 8 F 4 NPP Children s Hospital San Diego - San Diego, CA 2002 Sickle Cell Disease Sibling 2 M 3 NPP Medical City Dallas - Dallas, TX 2002 Acute Lymphocytic Leukemia Sibling 4 F 5 NPP City of Hope - Duarte, CA 2002 Acute Lymphocytic Leukemia Sibling 5 F 9 NPP City of Hope - Duarte, CA 2002 Aplastic Anemia Self 2 M 33 Family University of Minnesota - Minneapolis, MN 2001 Sickle Cell Disease Sibling 9 M 29 Family University of Michigan - Ann Arbor, MI 2001 Acute Myelogenous Leukemia Sibling 2 M 1 NPP City of Hope - Duarte, CA 2001 Acute Lymphocytic Leukemia Sibling 18 M 24 Family Children s Hospital of Philadelphia - Philadelphia, PA 2001 Acute Lymphocytic Leukemia Sibling 3 M 12 NPP University Medical Center - Tucson, AZ 2001 Chronic Myelogenous Leukemia Mother 43 F 35 NPP MD Anderson Cancer Center - Houston, TX 2000 Hurler Syndrome Sibling 2 F 2 NPP Children s Medical Center of Dallas - Dallas, TX 2000 Acute Lymphocytic Leukemia Sibling 3 M 23 NPP Children s Hospital of Wisconsin - Milwaukee, WI 2000 Acute Lymphocytic Leukemia Sibling 16 F 48 Family Devos Children s Hospital - Grand Rapids, MI 2000 Fanconi Anemia Sibling 4 M 12 NPP University Medical Center - Tucson, AZ 1999 Beta Thalassemia Major Sibling 3 F 6 NPP University Medical Center - Tucson, AZ 1999 Acute Lymphocytic Leukemia Sibling 6 M 9 Family University Medical Center - Tucson, AZ 1998 Acute Myelogenous Leukemia Sibling 4 F 14 Family University of Michigan - Ann Arbor, MI 1998 Acute Myelogenous Leukemia Sibling 5 M 1 Family Lucile Packard Children s Hospital at Stanford - Palo Alto, CA 1998 Acute Lymphocytic Leukemia Sibling 5 M 30 Family Kaiser Hospital Los Angeles - Los Angeles, CA 1996 Acute Myelogenous Leukemia Sibling 3 M 6 Family Children s Hospital Los Angeles - Los Angeles, CA 1996 Acute Lymphocytic Leukemia Sibling 6 M 2 NPP University Medical Center - Tucson, AZ 1995 Myelodysplastic Syndrome Sibling 9 F 14 NPP University Medical Center - Tucson, AZ 1993 Chronic Myelogenous Leukemia Sibling 1 M 2 NPP University of Minnesota - Minneapolis, MN Regenerative applications make up 73% of the cord blood units released by CBR. 1 73% 27% Regenerative Medicine Transplant Medicine CORD BLOOD: THE PROGRESS IS REAL Find out more at cordblood.com LAST UPDATED:

8 1.888.CORD BLOOD cordblood.com 1. Data on file. Ultimate use of newborn stem cells will be determined by the treating physician who will consider if they are applicable for the condition and should come from the patient or a suitable donor(siblings of the same biological parents have a 25% chance of being a perfect match and a 50% chance of being a partial match; biological parents will always be a partial match). There is no guarantee that treatments being studied in the laboratory, clinical trials, or other experimental treatments (including regenerative medicine applications) will be available in the future Cbr Systems, Inc. All rights reserved CBR-MKT-FS