Antibody Cross-Reactivity Chart

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Page 1 of 6 CD2 RPA-2.10 Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Capuchin Monkey, Swine (Pig, Porcine) CD3 SK7 Human Chimpanzee CD3 UCHT1 Human Chimpanzee CD4 OKT4 Human Chimpanzee, Cynomolgus, Rhesus CD4 RPA-T4 Human Chimpanzee CD5 UCHT2 Human Chimpanzee, Capuchin Monkey, Common Marmoset CD8a HIT8a Human Chimpanzee, Rhesus CD8a RPA-T8 Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Sooty Mangabey CD8a SK1 Human African Green, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus, Sooty Mangabey CD9 HI9a Human Horse (Equine), Cattle (Bovine, Cow), Sheep (Ovine), Dog (Canine), Rabbit (Lapine) CD10 HI10a Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Capuchin Monkey Chimpanzee, Baboon, Cynomolgus, Rhesus, Capuchin Monkey, Horse (Equine), Cattle CD11a HI111 Human (Bovine, Cow), Sheep (Ovine), Dog (Canine), Rabbit (Lapine) CD11b M1/70 Mouse, Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Rabbit (Lapine) CD11b ICRF44 Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Common Marmoset, Swine (Pig, Porcine) CD11c 3.9 Human Chimpanzee, Baboon, African Green, Cynomolgus, Rhesus, Squirrel Monkey CD11c Bu15 Human Cynomolgus CD13 WM15 Human Chimpanzee, Baboon, Cotton-topped Tamarin CD14 M5E2 Human Chimpanzee, Cynomolgus, Rhesus, Pigtailed Macaque, Capuchin Monkey, Cotton-topped Tamarin, Common Marmoset, Squirrel Monkey, Cattle (Bovine, Cow), Sheep (Ovine), Swine (Pig, Porcine), Dog (Canine) CD15 HI98 Human Chimpanzee Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Capuchin Monkey, CD16 3G8 Human Squirrel Monkey, Sooty Mangabey, Cotton-topped Tamarin, Marmoset CD18 TS1/18 Human Swine (Pig, Porcine) CD19 HIB19 Human Chimpanzee Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Capuchin Monkey, CD20 2H7 Human Squirrel Monkey CD22 HIB22 Human Chimpanzee CD24 ML5 Human Chimpanzee, Baboon CD25 BC96 Human Baboon, Chimpanzee, Cynomolgus, Rhesus, Pigtailed Macaque CD27 O323 Human Baboon, Cynomolgus, Rhesus, Squirrel Monkey Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Squirrel Monkey, CD28 CD28.2 Human Capuchin Monkey, Sooty Mangabey CD29 TS2/16 Human Cattle (Bovine, Cow) CD31 WM59 Human African Green, Baboon, Cynomolgus, Rhesus CD33 HIM3-4 Human Chimpanzee CD33 WM53 Human Chimpanzee

Page 2 of 6 CD34 561 Human Cynomolgus, Rhesus CD34 581 Human Cynomolgus CD38 HIT2 Human Chimpanzee CD39 A1 Human Rhesus CD40 5C3 Human Baboon, Chimpanzee, Cynomolgus Monkey, Rhesus, Squirrel Monkey CD40 HB14 Human Rhesus CD41 HIP8 Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Capuchin Monkey CD42b HIP1 Human Chimpanzee Baboon, Chimpanzee, Cynomolgus, Rhesus, Squirrel Monkey, Horse (Equine), Cattle CD44 IM7 Mouse, Human (Bovine, Cow), Swine (Pig, Porcine), Dog (Canine), Cat (Feline) CD45 HI30 Human Chimpanzee CD45R RA3-6B2 Mouse, Human Cat (Feline) CD45RA HI100 Human Chimpanzee CD45RO UCHL1 Human Chimpanzee, Common Marmoset CD49b AK-7 Human Baboon, Capuchin, Chimpanzee, Cynomolgus, Rhesus Baboon, Chimpanzee, Common Marmoset, Cynomolgus, Rhesus, Squirrel Monkey, Horse CD49d 9F10 Human (Equine), Cattle (Bovine, Cow), Sheep (Ovine), Dog (Canine), Cat (Feline) CD49e NKI-SAM-1 Human Cynomolgus Macaque CD49f GoH3 Human, Mouse Baboon, Chimpanzee, Capuchin Monkey, Cynomolgus, Rhesus, Horse (Equine), Cattle (Bovine, Cow), Sheep (Ovine), Swine (Pig, Porcine), Dog (Canine), Cat (Feline), Rabbit (Lapine) CD51/61 23C6 Human Rabbit (Lapine), Chicken CD53 HI29 Human Chimpanzee CD54 HCD54 Human Chimpanzee CD54 MEM-111 Human Cynomolgus, Cattle (Bovine), Rat CD56 MEM-188 Human Cattle (Bovine, Cow), Swine (Pig, Porcine) CD59 p282 (H19) Human Chimpanzee, Baboon, Cynomolgus, Rhesus CD61 VI-PL2 Human Baboon, Rhesus, Cynomolgus CD62L DREG-56 Human Chimpanzee, Cattle (Bovine, Cow) CD62P AK4 Human Chimpanzee CD64 10.1 Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Capuchin Monkey, Squirrel Monkey CD66b G10F5 Human Chimpanzee CD69 FN50 Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque CD74 LN2 Human Baboon, Rhesus CD80 16-10A1 Mouse Dog (Canine) CD80 2D10 Human Rhesus

Page 3 of 6 CD81 5A6 Human Chimpanzee CD83 HB15e Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque Baboon, Capuchin Monkey, Common Marmoset, Cotton-topped Tamarin, Chimpanzee, CD86 IT2.2 Human Cynomolgus, Rhesus CD89 A59 Human Cynomolgus Monkey CD90 5E10 Human Baboon, Cynomolgus, Rhesus, Pigtailed Macaque CD90.1 OX-7 Rat, Mouse (AKR/J and PL mouse strains) Rabbit (Lapine), Guinea Pig CD95 DX2 Human African Green, Baboon, Capuchin Monkey, Chimpanzee, Common Marmoset, Cottontopped Tamarin, Cynomolgus, Pigtailed Macaque, Rhesus, Sooty Mangabey CD100 A8 Human Cynomolgus CD103 Ber-ACT8 Human Cynomolgus CD107a H4A3 Human African Green, Baboon, Chimpanzee, Pigtailed Macaque, Rhesus CD117 104D2 Human Cynomolgus, Cattle (Bovine, Cow) CD132 TUGh4 Human Dog CD134 Ber-ACT35 (ACT35) Human Chimpanzee CD137 4B4-1 Human Chimpanzee, Baboon, Cynomolgus, Rhesus CD147 HIM6 Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Capuchin Monkey CD150 A12 (7D4) Human Baboon, Cynomolgus, Rhesus CD154 24-31 Human Cynomolgus, Rhesus CD161 HP-3G10 Human Baboon, Chimpanzee, Rhesus CD162 KPL-1 Human Cynomolgus CD163 GHI/61 Human Rhesus CD170 1A5 Human Chimpanzee, Bonobo, Gorilla CD177 MEM-166 Human Rhesus CD179b HSL11 Human Rhesus CD180 MHR73-11 Human Baboon, Cynomolgus, Rhesus CD183 G025H7 Human Cynomolgus, Rhesus CD184 12G5 Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Sooty Mangabey, African Green CD196 G034E3 Human Cynomolgus, Rhesus CD197 G043H7 Human Cynomolgus, Rhesus CD209 DCS-8C1 Human Macaque CD210 3F9 Human Cynomolgus, Rhesus CD222 MEM-238 Human Rhesus CD226 DX11 Human Chimpanzee, Baboon, Cynomolgus, Rhesus CD271 ME20.4 Human Monkey, Raccoon, Sheep, Cat, Dog, Pig, Rabbit

Page 4 of 6 CD274 29E.2A3 Human African Green, Chimpanzee, Common Marmoset, Squirrel Monkey CD278 C398.4A Human, Mouse, Rat Swine (Pig, Porcine) CD279 EH12.2H7 Human Chimpanzee, Common Marmoset, Cynomolgus, Rhesus, Squirrel Monkey CD284 HTA125 Human Guinea Pig, Rhesus CD290 3C10C5 Human Cynomolgus CD317 RS38E Human Pigtailed Macaque, Rhesus CD354 TREM-26 Human Dog (Canine) CD360 2G1-K12 Human Cynomolgus β-arrestin-1 25-G10 Human, Mouse, Rat Bovine β2-microglobulin 2M2 Human Swine (Pig, Porcine) Alix 3A9 Human, Mouse Frog ATIC F38P7H9 Human, Mouse, Rat Frog, Fruit fly Bax 6A7 Human, Mouse, Rat Monkey BCL-X S/L 2H12 Human, Mouse, Rat Porcine Bcl11b 25B6 Human, Mouse Zebrafish Biotin 1D4-C5 All species All species c-myc 9E10 All species All species cdc2 (p34) POH-1 Human Monkey, Cattle (Bovine) Cyclin A E23.1 Human, Mouse Bovine Cytochrome c 7H8.2C12 Most Species Most Species Cytokeratin (pan reactive) C-11 All species All species Cytokeratin 7/17 C-46 Human Bovine, Porcine FOXP3 150D Human, Mouse, Rat Cynomolgus, Rhesus, Baboon FOXP3 206D Human Baboon, Cynomolgus, Rhesus, Pigtailed Macaque FOXP3 259D Human Cynomolgus, Rhesus, Baboon, Chimpanzee GAPDH Poly6314 Human, Mouse, Rat Rabbit GFAP 2E1.E9 Human, Mouse, Rat Other species GM-CSF BVD2-21C11 Human Cynomolgus, Rhesus HLA-A,B,C W6/32 Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Cattle (Bovine, Cow), Cat (Feline) African Green, Baboon, Chimpanzee, Common Marmoset, Cotton-topped Tamarin, HLA-DR L243 Human Cynomolgus, Pigtailed Macaque, Rhesus, Squirrel Monkey, Dog (Canine) HLA-DR LN3 Human Rhesus hnrnpk F45P9C7 Human, Mouse, Rat Rabbit, Chicken IFN-γ 4S.B3 Human Chimpanzee, Baboon, Cynomolgus, Rhesus

Page 5 of 6 IFN-γ B27 Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, African Green, Sooty Mangabey IFN-γ MD-1 Human Chimpanzee, Baboon, Cynomolgus, Rhesus IgG Fc HP6017 Human Goat, Rabbit, Sheep, Horse IL-1α 364-3B3-14 Human Rhesus IL-1β JK1B-1 Human Baboon IL-2 MQ1-17H12 Human Chimpanzee, Baboon, Cynomolgus, Rhesus, Sooty Mangabey IL-2 Poly5111 Human Old World Monkey, Baboon IL-4 8D4-8 Human Chimpanzee, Baboon, Cynomolgus, Rhesus IL-4 MP4-25D2 Human Swine (Pig, Porcine), Rhesus IL-5 JES1-39D10 Human Cynomolgus, Rhesus IL-5 JES1-5A10 Human Cynomolgus, Rhesus IL-5 TRFK5 Mouse, Human Guinea Pig IL-10 JES3-9D7 Human Baboon, Rhesus, Cynomolgus IL-21 3A3-N2 Human Rhesus Integrin α9 β1 Y9A2 Human Guinea pig Integrin β7 FIB504 Human, Mouse Chimpanzee, Baboon, Cynomolgus, Rhesus MAP2ab MT-08 Human, Mouse Porcine MCP-1 5D3-F7 Human Cynomolgus, Rhesus Neurofilament heavy protein NF-01 All species All species Neurofilament medium protein NF-09 All species All species NGF JKhNGF-1 Human Cattle (Bovine, Cow), Viper NGF JKhNGF-2 Mouse, Human Cattle (Bovine, Cow), Viper p53 BP53-12 Human Non-human primates PCNA PC10 Human, Mouse, Rat Other species Perforin dg9 Human Bovine (Cow, Cattle) Phosphotyrosine PY20 All Species All Species TCP-1 beta F39P7F11 Human, Mouse, Rat Frog TCR α/β R73 Rat Cynomolgus, Rhesus TCR γ/δ B1 Human Baboon, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus TCR Vα24-Jα18 6B11 Human Rhesus, Pigtailed Macaque, Sooty Mangabey TCR Vβ5 MH3-2 Human Macaque TCR Vδ2 B6 Human Chimpanzee, Rhesus TCR Vγ9 B3 Human Chimpanzee, Cynomolgus

Page 6 of 6 TIMP-1 F31P2A5 Human Monkey TIMP-2 F27P3A4 Human, Mouse Rabbit, Chicken, Zebrafish, Pig Chimpanzee, Baboon, Cynomolgus, Rhesus, Pigtailed Macaque, Sooty Mangabey, Swine TNF-α MAb11 Human (Pig, Porcine) TNF-α TN3-19.12 Mouse, Rat Rabbit (Lapine) Tubulin-α 10D8 Human, Mouse, Rat All species Tubulin-α TU-01 All species All species Ubiquitin P4D1 All species All species References: 1. http://www99.mh-hannover.de/aktuelles/projekte/hlda7/animals/xreact.htm (7th International Workshop on Human Leukocyte Differentiation s CD s Section, Cross-Reactions Overview) 2. http://txbiomed.org/primate-research-center (Southwest National Primate Research Center) 3. http://nhpreagents.bidmc.harvard.edu/nhp/reagentlist.aspx Note: * The provided cross-reactivity of monoclonal antibodies to other species have been reported in the literature or website, but are not tested at BioLegend. ** The cellular distribution or specific reactivity may vary from different species or between individual animals.