PARKINSON S DISEASE MULTIPLE DOMAINS



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PhD PROGRAM IN NEUROPHARMACOLOGY UNIVERSITY OF CATANIA SUMMER SCHOOL OF NEUROSCIENCE (5) Quinta scuola estiva di Neuroscienze (5) July 7-13, 2007 PARKINSON S DISEASE MULTIPLE DOMAINS Catania Parco degli Aragonesi Hotel Viale Kennedy, 2

Scientific Advisory Board Filippo Drago (Catania) (Chairman) Eugenio Aguglia (Trieste) Pier Luigi Canonico (Novara) Vincenzo Cuomo (Rome) Donatella Marazziti (Pisa) Giancarlo Pepeu (Florence) Giorgio Racagni (Milan) Maria Angela Sortino (Catania) Mario Zappia (Catania) Scientific Secretariat Filippo Caraci (Catania)

Saturday July 7 th, 2007 09.00-09.45 Registration 09.45-10.00 Opening remarks Filippo Drago (Catania) 10.00-11.00 Opening lecture (introduced by Filippo Drago) L-DOPA treatment: 40 years later Mario Zappia (Catania) 11.00-11.30 Welcome reception Parkinson s disease: general features Mario Zappia (Catania) 16.00-17.00 Epidemiology and risk factors in PD Alessandra Nicoletti (Catania) 17.00-18.00 Genetics of PD Giovanni Savettieri (Palermo) 18.30-19.30 Stem cells in Parkinson s disease Eldad Melamed (Tel Aviv)

Sunday July 8 th, 2007 Neurobiology and neurophysiology of basal ganglia Giancarlo Pepeu (Florence) 10.00-11.00 The neurobiology of dopaminergic signalling Pierfranco Spano (Brescia) 11.00-12.00 Functional aspects of basal ganglia Vincenzo Perciavalle (Catania) 12.30-13,30 Lecture (sponsored) Parkinson s disease: from neurobiology to clinics Vincenzo Perciavalle (Catania) 16.00-17.00 NMDA receptor in L-DOPA induced dyskinesia Monica Di Luca (Milan) 17.00-18.00 Premorbid personality and affective disorder in Parkinson s disease Letterio Morgante (Messina) 18.30-19.30 Special Lecture The diagnosis of PD Alberto Albanese (Milan)

Monday July 9 th, 2007 Parkinson s disease: neuropharmacology Pierfranco Spano (Brescia) 10.00-11.00 The cholinergic system in the basal ganglia and the muscarinic receptor antagonists Giancarlo Pepeu (Florence) 11.00-12.00 Adenosine receptors in Parkinson s disease Ana Sebastiao (Lisbon, Portugal) 12.30-13.30 Lecture (sponsored) Parkinson s disease: cognitive and motor function Renato Bernardini (Catania) 16.00-17.00 Cognitive function in Parkinson s disease Francesco Le Pira (Catania) 17.00-18.00 A comprehensive approach to Parkinson Disease patients Leandro Provinciali (Ancona) 18.30-19.30 Special lecture Lewy Body Dementia: basic and therapeutic strategies Alessandro Padovani (Brescia)

Tuesday July 10 th, 2007 Parkinson s disease: animal models Agata Copani (Catania) 10.00-11.00 PD and related disorders: animal models Fabio Blandini (Pavia) 11.00-12.00 α-synuclein and the proteosome system in PD and related disorders Francesco Fornai (Pisa) 12.30-13.30 Lecture (sponsored) Parkinson s disease: clinics and treatment Francesco Le Pira (Catania) 16.00-17.00 Postural stability in Parkinson s disease Giovanni Abbruzzese (Genova) 17.00-18.00 Responsivity to treatment and pharmacogenomics in PD Aldo Quattrone (Catanzaro) 18.30-19.30 Deep Brain Stimulation in PD Leonardo Lopiano (Torino) 19.30-19.40 Questionnaire

Wednesday July 11 th, 2007 Parkinson s disease: neuropharmacology and neuropathology Maria Angela Sortino (Catania) 10.00-11.00 The endocannabinoid system in basal ganglia: implications for the treatment of Parkinson s disease Walter Fratta (Cagliari) 11.00-12.00 Neuropathology of PD: activation of the unfolded protein response Jeroen Hoozemans (Amsterdam, The Netherlands) 12.30-13.30 Lecture (sponsored) Psychiatric comorbidity in PD Fabrizio Stocchi (Rome) 16.00-17.00 Psychosis in PD Eugenio Aguglia (Trieste) 17.00-18.00 Depression in PD Donatella Marazziti (Pisa) Special lecture 18.30-19.30 Dopaminergic modulation of cognitive function in Parkinson's disease Roshan Cools (Cambridge, UK)

Thursday July 12 th, 2007 Parkinson s disease: experimental models Pier Luigi Canonico (Novara) 10.00-11.00 Experimental models of PD and basic mechanisms of striatal synaptic plasticity Antonio Pisani (Rome) 11.00-12.00 Energy metabolism impairment and neuronal vulnerability in PD Nicola Biagio Mercuri (Rome) 12.30-13,30 Lecture (sponsored) Dopaminergic system in Parkinson s disease Nicola Biagio Mercuri (Rome) 16.00-17.00 Dopamine agonists in PD Ubaldo Bonuccelli (Pisa) 17.00-18.00 Dopamine dysregulation syndrome in Parkinson's disease Giovanni Fabbrini (Rome) 18.30-19.30 Inhibition of dopamine metabolism in the treatment of PD Fabrizio Stocchi (Rome) 21.00 Social Dinner

Friday July 13 th, 2007 Parkinson s disease:neurobiology and neuropharmacology Giovanni Fabbrini (Rome) 10.00-11.00 Pathogenetic mechanisms of inherited PD Enza Maria Valente (Rome) 11.00-12.00 Metabotropic glutamate receptors as new therapeutic targets for the treatment of PD Ferdinando Nicoletti (Rome) 12.30-12.45 Closing remarks Filippo Drago (Catania) 12:45-12:55 Questionnaire