Collaborative Research in the Institut Pasteur International Network

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Collaborative Research in the Institut Pasteur International Network Institut Pasteur Center for Global Health Golbahar Pahlavan, Deputy Director Brussels, September 28 th 2016

Institut Pasteur & Institut Pasteur International Network The Institut Pasteur is a private, non-profit foundation focused on basic sciences for the benefit of public health since 1887. Mission: to help prevent and treat diseases, mainly those of infectious origin, through research, teaching, and public health initiatives. Louis Pasteur vision : to improve human health and welfare through scientific discovery Science has no native land, as knowledge is the heritage of humankind, the torch that lights up the world Science has no native land, as knowledge is the heritage of humankind, the torch that lights up the Louis world Pasteur Louis Pasteur

Institut Pasteur Center for Global Health Promote research using state-of-the-art technology to address the most significant public health challenges worldwide Educate and equip the next generation of global health scientists and practitioners Support local authorities in the management and response to infectious disease outbreaks and better understand emergence and transmission patterns in order to limit further spread in human populations

Institut Pasteur International Network (IPIN) 33 Pasteur institutes, 9500 researchers in 26 countries across 5 continents Strong bonds within the local health and education systems Active national and international scientific collaborations Cross sectoral partnerships to tackle global health challenges

Institut Pasteur Paris 130 Research Units 10 Nobel laureates (HIV) 11 Scientific Departments 2500 employees 14 National Reference centers & 8 WHO collaborating centers Microbiology Infectious diseases Immunology Neurosciences Stem cells Cancer 55 000 m 2 in the heart of Paris Industrial partnerships More than 60 nationalities 500 Master, PhD & Postdocs per year

Research areas linked to public health priorities Most important causes of lethality in children: encephalitis, respiratory infections, diarrhea Basic Science Translational Research Diagnostics Vaccines Pandemic diseases : HIV, Malaria, Tuberculosis, Influenza, Polio Emerging and new pathogens (vector-borne infections, coronavirus, ) Drug resistance (Antibiotics, Malaria, HIV, Tuberculosis, Leshmaniasis, ) Neglected diseases : Buruli ulcer, Rabies, Dengue NCDs Point of Care and access to diagnosis

Double-Pronged Collaborative Research Strategy Strengthening collaborations within IPIN Initiate New Subjects Maturing projects with strong applicative potential ACIP/PTR Transversal Programs Internal ValoExpress / PasteurInnov Partnerships Research foundations GPF Major Federating Programs calls For proposals AIC Targeted Incentive Actions Research centers Public authorities International Organizations Companies/industries Philanthropy Collaboration at interdisciplinary levels in strongly emerging fields Developing international consortia on public health issues or specific topics Donors

Global Health Security IHR Outbreak Surveillance, Preparedness & Response - Regional laboratory workshops - Post Ebola in West Africa - Zika Research projects and Consortia PRNDs, AMR, Malnutrition, Microbiome - TB consortium - Malaria consortium - Venoms and Toxins One Health Projects Emerging viruses, Zoonoses - Antibiotic resistance - Environmental impact - Emerging, re-emerging pathogens Transversal Projects and Actions Technology & incubation platforms - Biobanking - Bioinformatics - Technology transfer and IP

Training and education at IPIN Lab & field hands-on training 15 to 25 Regional courses each year

PanAfrican Coalition for Research and Public Health (PACT) 1/3 Anchored on the 10 African Institut Pasteur Historic links with local universities and health systems Scientific expertise Training and supervision experience and facilities National and international partnerships

PACT : A multi-country & multi-partner coalition 2/3 Objectives: Strengthen African universities by providing training through research programs based on local needs, Provide intra-african mobility grants from MSc to postdoc levels, Provide management and leadership skills in partnership with ongoing initiatives, Increase the access of women to leadership positions in research and public health, Bridge the linguistic barriers to productive academic and research collaborations throughout Africa, Improve the employability of young researchers by providing sustainable career tracks in partnership with local and regional stakeholders including the private sector.

PanAfrican Coalition for Research and Public Health (PACT) 3/3 Human genomics and genetics Tunisia Regional MSc Bioinformatics Senegal Malariology Ivory Coast Medical microbiology Cameroon Outbreak preparedness & response Guinea IP project coordinator Project members Potential project member (in progress) Potential transversal partners PhD track African host lab lab networks networks Post-doc exchanges Placement in the private sector Summer schools Research Research career career fair fair

Thank you!

A global Interface across the Institut Pasteur network Transversal Centers 11 scientific departments in Paris 33 Institut Pasteur International Network Multidisciplinary collaborations