CDC s s Approach to Global Networking, Collaboration, and Data Exchange Stephen B. Blount, MD, MPH Director, Coordinating Office for Global Health US Centers for Disease Control and Prevention WWW.CDC.GOV
Why collaborate? 2
Shared problem 3
Shared responsibility International Health Regulations (2005) New expectations for all WHO member states Outbreak detection Field investigation Risk assessment Intervention 4
Shared solution Capacity building: Support for global public health governance Those with capacity must help those without (Article 44) Must build local, regional, and global public health infrastructure in resource-constrained countries 5
Shared network Network tested >120,000 stool samples in 2007 Specialized Reference Laboratory Regional Reference Laboratory National/ Sub-national Laboratory Global Polio Laboratory Network, 2008
CDC support for WHO Polio Lab Network $3.2 million for polio lab network (out of $27 million for polio in FY09) Funding includes 8 CDC employees, equipment, supplies, and support for operation of regional polio reference labs 7
CDC support for Global Disease Detection Mission Global public health security mitigate the consequences of a catastrophic public health event, whether the cause is an intentional act of terrorism or the natural emergence of a deadly infectious virus Congress, 2004 8
Global Disease Detection Mission Global coverage Accomplished through 3 overarching mechanisms: GDD Regional Centers (6 sites, 6 WHO regions) GDD Operations Center (based in Atlanta) Other CDC programs overseas 9
Global Disease Detection Countries with CDC staff GDD Regional Center GDD Operations Center 10
Global Disease Detection Mission Global coverage Global integration A connected network: WHO HQs and Regional Centers Global Outbreak Alert and Response Network (GOARN) Ministries of Health Partners: interagency, bi-lateral, multilateral, private 11
Global Disease Detection Mission Global coverage Global integration Global capacities Disease detection and response Training in field epidemiology and laboratory methods Pandemic influenza preparedness and response Zoonotic disease investigation and control Health communication and Information Technology Laboratory systems and biosafety 12
Global Disease Detection Mission Global coverage Global integration Global capacities Global impact Outbreak response: Responded to more than 231 outbreaks since 2006 Surveillance: Established local diagnostic capacity for more than 30 conditions through technology transfer Pathogen discovery: Discovered 16 pathogens Training: Trained 78 future global health leaders through Field Epidemiology Training Programs; more than 7,000 participants trained through short-term exercises Networking: Expanded key collaborations with international and regional partners 13
Global Disease Detection A Novel Arenavirus, October 2008 Mission Global coverage Global integration Global capacities Global impact 36-year old safari booking agent in Zambia Flu-like illness, eschar between toes, deterioration, death Similar disease in paramedic, nurse, janitor Onset to death in 9-12 days Samples tested in Johannesburg and Atlanta Negative for Ebola, Marburg, CCHF, Lassa, others Immunohistochemistry and PCR hints Novel Old World Arenavirus as cause 14
Collaboration with Institut Pasteur Influenza sentinel surveillance workshop for francophone Africa Conducting clinical, diagnostic studies of plague and evaluating rapid diagnostic tests with IP- Madagascar Training microbiologists and epidemiologists through WHO Global Salm-Surv to address foodborne and other infectious enteric diseases Characterizing new serovars of Salmonella Improving melioidosis control through better diagnostic capacity and assessing the genomic diversity of Burkholderia pseudomallei 15
Shared vision A global commitment to networking, collaboration, and data exchange means a safer, healthier world for all 16