THERALASE COLD LASER THERAPY



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Healing at the Speed of Light PAIN TREAT HEAL PROFIT THERALASE COLD LASER THERAPY For Humans

THERALASE Founded in 1994, Theralase builds the finest therapeutic medical lasers in the world Theralase designs, develops and manufactures patented, superpulsed laser technology utilized in biostimulative applications. The technology is safe and effective in the treatment of pain, inflammation, neuromuscular skeletal conditions and wound care for the human, equine and companion animal markets. Founded in 1994, Theralase is committed to provide cutting-edge preclinical and clinical research to remain the most clinically and scientifically supported therapeutic medical laser on the market. The highly trained Theralase team continuously brings our valued customers the most advanced technology on the market, superior customer service, the latest interactive training and the most up to date clinical protocols to accelerate the success of their practice. Used by thousands of medical practitioners worldwide and improving the lives of human patients for over 17 years, the award winning Theralase TLC-1000 laser technology is now being offered to all healthcare practitioners as a modern way to treat pain and inflammation safely and effectively. Pg.2

NEUROMUSCULAR SKELETAL CONDITIONS Eliminating PAIN AND INFLAMMATION Neuromuscular skeletal conditions are common in all of us. We can all experience sprains, strains and pain that just won t go away resulting from repetitive strains in our work place or from trauma in our everyday lives. Pain and inflammation are things we ve grown to accept as something we probably will just have to live with. Medical practitioners across North America have discovered a modern medical technology that heals injuries safely and effectively on a cellular level. This medical technology is the Theralase line of therapeutic medical laser systems. The Theralase superpulsed laser system can penetrate up to 4 inches into tissue, to promote cellular regeneration at the source of injury. Laser energy helps to repair damaged cells by accelerating the body s natural healing mechanisms. Depending on the severity of the injury, your patient can return to an active lifestyle pain-free within a few weeks versus months or years of life altering pain. Pg.3

THE SCIENCE BEHIND THE PRODUCT Superpulsed 905 nm technology penetrates up to 4 into tissue Safe and Effective Theralase s superpulsed 905 nanometer (nm) near infrared and 660 nanometer (nm) visible red laser technology accelerates healing by reducing pain and inflammation while staying below the Maximal Permissible Exposure (MPE) tolerance for tissue. Theralase s dual wavelength technology 905 nm LED 905 nm CW Laser 905 nm Superpulsed Laser 660 nm Continuous Wave Laser 5mW CONTINUOUS WAVE 100mW CONTINUOUS WAVE 50,000mW SUPER PULSED (INSTANTANEOUS) 25mW CONTINUOUS WAVE TISSUE SURFACE 1 2 Penetration Depth 1 Penetration Depth 5 mw Cm 2 1.8 mw / cm 2 0.7 mw / cm 2 100 mw/cm 2 37 mw / cm 2 14 mw / cm 2 50,000 mw / Cm 2 18,450 mw / cm 2 6,810 mw / cm 2 25 mw Cm 2 3.4 mw / cm 2 0.5 mw / cm 2 Pulsing at 50,000 mw up to 10,000 times per second, the Theralase 905 nm super pulsed laser is able to deliver an exact dose of light energy up to 4 into tissue. 4 Penetration Depth 0 mw / cm 2 0 mw / cm 2 2,5 mw / cm 2 0 mw / cm 2 Dual wavelength TECHNOLOGY Theralase combines 660 nm visible red and 905 nm near infrared superpulsed lasers to allow superficial and deep penetration of laser energy of up to 4 into tissue activating all three known cellular pathways. True Laser Diodes Versus LEDs True lasers are highly directional delivering 100% of the photons to the affected area versus only 5 to 6% with a LED; hence, much better treatment outcomes occur with true lasers versus LEDs. Laser - 100% of light energy in the forward direction LED - 5 to 6 % of light energy in the forward direction Theralase Laser LED 100 mw x 100%= 100 mw 15 mw x 6%= 0.9 mw Shorter Treatment Times The Theralase Multiple Probe utilizes 9 Lasers and is able to treat an area of 20cm 2 thus reducing treatment times by 90% in comparison to a single laser probe. Pg.4

THE SCIENCE BEHIND THE PRODUCT theralase is the only laser on the market known to activate all three cellular pathways 660 nm - Adenosine Triphosphate (ATP) Pathway: Healing Theralase stimulates the mitochondria of the cell to produce more Adenosine Triphosphate (ATP or basic cell energy) to accelerate tissue repair. (Proceedings of the National Academy of Science 2003) Cells that lack energy are unable to participate in the healing process. Laser energy is delivered to injured cells, which are able to absorb the light and convert it into chemical energy, which is then used to accelerate tissue repair. Once cells are fully energized they are able to stimulate each other to rebuild and heal the injured area. 905 nm - Nitric Oxide (NO) Pathway: Inflammation Independent research proves that the proprietary Theralase 905nm superpulsed laser technology increases the production of NO by over 700%, increasing vasodilation and decreasing inflammation versus other competitive wavelengths. (Lasers in Surgery and Medicine, 2009). When tissue injury occurs, the inflammatory process is initiated to immobilize the area and prevent further damage to our body. This process is usually associated with pain caused by inflammation exerting pressure on nerve endings. In order to decrease inflammation in the particular region, the body produces Nitric Oxide (NO). Nitric Oxide has been proven to relax the vascular network, dilate the capillaries, improve vascular function, protect against cell injury and help rebalance the immune response. This process not only reduces inflammation but brings much needed oxygen and other metabolites to the injured tissue aiding in their natural healing. Cristae Matrix Inner Membrane Outer Membrane 905 nm - Lipid Absorption Pathway: Pain Theralase laser technology effectively removes the pain signal at source by rebalancing the sodium potassium pathway. (Harvard Medical School 2010) Neurons use electrical and chemical signals to transmit information. The transmission of pain is primarily due to an expulsion of sodium ions (Na+) and an influx of potassium (K+) ions into the nerve cell across the cellular membrane, altering the electrical potential difference of the nerve cell. The peak absorption of lipids occurs in the near infrared wavelength range of 905 nm to 910 nm. Since the cellular membrane is a bilipid membrane, laser light in the 905 nm range increases the porosity of the cellular membrane. This increased cellular membrane porosity allows the reabsorption of sodium ions and the expulsion of potassium ions across the membrane rebalancing the sodium-potassium pump and removing the pain signal at source. Extracellular fluid with high concentration of Na+ Cell membrane K+ Na+ Na+ K+ ATP ADP Na+ Na+ Na+ Intracellular fluid with low concentration of Na+ and high concentration of K+ Pg.5

TREATABLE CONDITIONS (partial list) OVER 70 CLINICALLY proven PRE-PROGRAMMED TREATMENTS Migraines Frozen Shoulder Herpes Simplex Tennis / Golfer s Elbow Bicipital Tendinitis Neck Pain Rotator Cuff Tears Psoriasis Low Back Pain Carpal Tunnel Syndrome Sciatica Knee Pain Iliotibial Band Syndrome Achilles Tendinitis Medial / Lateral Collateral Ligament Tears Pg.6

TREATMENT Efficacy rates of up to 90% with no side effects Decrease / eliminate pain Reduce inflammation Promote new blood vessels and tissue growth Promote nerve axon growth Faster wound healing and closure Non-Invasive / No side effects Extremely Safe / drug free Highly effective for patient (90% efficacy rates) Highly effective alternative to other treatments; such as Analgesics, NSAID s, COX-2 Inhibitors, TENS, Ultrasound, Inferential therapy Acute CONDITIONS 5 Treatment sessions* Sub-acute CONDITIONS 10 Treatment sessions* CHRONIC CONDITIONS 20 Treatment sessions* * Typical number of 8-10 minute sessions Pg.7

BUT DON T TAKE OUR WORD FOR IT... HERE S WHAT Healthcare Practitioners ARE SAYING ABOUT THERALASE JAMES ANDREWS, MD, Birmingham, Alabama Our rehab specialists have reported outstanding success when using the Theralase therapeutic laser system for rehabilitation of certain knee, shoulder, elbow and other neuromuscular skeletal conditions. The Theralase laser is now a standard of care treatment methodology within our rehab clinics and is a great tool in helping our athletes return to competition. LAURENCE ALTSHULER, MD, Oklahoma City, Oklahoma The most advanced laser I have used is the Theralase therapeutic laser system, which I have now utilized for over one year and with which I have treated over 1000 patients. The Theralase is my first choice of treatment for patients with arthritis of any joint as well as degenerative disc disease. I also recommend the Theralase for TMJ, carpal tunnel, tendonitis and foot problems such as plantar fasciitis. The results have been excellent. KEVIN WILK, DPT, Birmingham, Alabama I love the Theralase medical laser system and use it in our clinic at least 20 times per day. Theralase is great for healing soft tissue injuries, damaged articular cartilage, ligament, muscle and tendon lesions - pretty much any muscular skeletal condition that I see at Champion Sports Medicine. I had one of my physical therapists use it on their plantar wart excisions site that wasn t healing and Theralase healed it in just a few days! Remarkable! I really love the Theralase and my patients love it too. GEORGE POULIS AND DAVE ABRAHAM, ATS, Toronto, Ontario The Theralase laser is the most effective technology we have ever used. Our players (Toronto Blue Jays) now rely on Theralase to keep them healthy and playing at their peak. ALBERT SCALES, DC, St. Catherines, Ontario I first purchased a therapeutic unit 2 years ago. The Theralase laser system quickly doubled my referrals within a few weeks. Initially, I used it to complement my other treatment modalities including ultrasound and electrotherapy. I have recently upgraded to a more powerful system and now use it as a stand alone therapy that has replaced all other modalities. I m averaging 200 laser treatments per month. The cost of the upgrade was offset within 3 months. Pg.8

CLINICAL PROOF over 3,000 clinical studies worldwide have proven the effectiveness of laser therapy EFFICACY OF LOW-LEVEL LASER THERAPY IN THE MANAGEMENT OF NECK PAIN: a SYSTEMatIC REVIEW AND META-ANALYSIS OF RANDOMIZED PLACEBO OR ACTIVE TREATMENT CONTROLLED TRIALS Roberta Chow et al. The Lancet, November 2009 Sixteen randomized controlled clinical trials were identified for analysis totalling 820 patients. In acute neck pain, results of two trials showed a relative risk (RR) of 1.69 for pain improvement for LLLT versus placebo. Five trials of chronic neck pain showed a RR for pain improvement of 4.05 using LLLT. Eleven trials reported reductions in pain intensity when measured using the Visual Analog Scale. Seven trials provided follow up data for 1 to 22 weeks and saw short term pain relief persisting in the medium term using LLLT. Side effects from LLLT were mild and not different from those of placebo. Study Conclusion: LLLT reduces pain immediately after treatment in acute neck pain and for up to 22 weeks after completion of treatment in patients with chronic neck pain. Effects of 904 NM low-level laser therapy in the management of lateral epicondylitis: a randomized Controlled trial Lam and Chein. Photomedicine and Laser Surgery, April 2007 The study evaluated the effectiveness of 904 nm Low Level Laser Therapy (LLLT) in the management of lateral epicondylitis. Thirty-nine patients with lateral epicondylitis were examined and treated with pain levels determined by the Visual Analog Scale. The study revealed that LLLT in addition to exercise is effective in improving the grip strength and subjective rating of physical function of patients with lateral epicondylitis. Study Conclusion : LLLT is highly effective in treating lateral epicondylitis efficacy of 904 NM gallium arsenide low level laser therapy in the management of chronic myofascial pain in the neck: a double blind and randomized controlled trial Ali Gur, MD et al. Lasers in Surgery and Medicine, 2004 A prospective, double blind, randomized and controlled trial was conducted in patients with chronic myofascial pain syndrome (MPS) in the neck to evaluate the effects of infrared low level 904 nm Gallium Arsenide (GaAs) laser therapy (LLLT) on clinical and quality of life. Results showed that the laser group experienced a significant improvement in pain at all outcome measures (p<0.01) over the placebo group. Study Conclusion: LLLT is highly effective in treating Chronic Myofascial Pain Syndrome Pg.9

TURN-KEY SOLUTION product, support and Clinical Knowledge to grow your practice Product Description SINGLE PROBE NIR Laser diode : 1x905 nm (collimated): Average power: 100 mw Peak power: 50,000 mw Treatment area: 0.1 cm 2 *NIR= Near Infrared / *VR= Visible Red TRIPLE PROBE NIR Laser diode : 1x905 nm: Average power: 100 mw Peak power: 50,000 mw VR Laser diode: 2x660: Average power: 25 mw Treatment area size: 3 cm 2 *NIR= Near Infrared / *VR= Visible Red MULTIPLE PROBE NIR Laser diode: 5x905 nm: Average power: 100 mw Peak power: 50,000 mw VR Laser Diode: 4x660 nm: Average power: 25 mw Treatment area size: 20 cm 2 *NIR= Near Infrared / *VR= Visible Red Interactive Training Theralase provides operational and clinical protocol training through interactive training resources available online or via DVD. Simply watch our videos to see how to safely and effectively operate your Theralase laser for a variety of medical conditions. Clinical Support Theralase provides ongoing clinical support through monthly webinars on pertinent clinical topics and on-staff healthcare practitioners who are available to discuss patient treatment plans and protocols. Pg.10 Marketing Support Theralase offers a number of highly effective marketing support materials. An online library of professionally developed marketing materials is accessible 24/7 exclusively to Theralase customers. Technical support Theralase offers extended warranty and loaner programs, so you can keep working while your system is being professionally serviced. CONTROLLER Portable light weight design. Battery operated (rechargable). Real time beam detector measures the amount of actual output power emitted from the probe tip. Retains up to 256 patient protocols in memory. STAND Custom made to fit the Theralase system. Portable light weight design with wheels for easy transportation within the clinic. Adjustable boom arm that allows for hands free treatment with all laser probes C US LR2278288 0473 Health Canada

FINANCIAL BENEFITS INCREASED REVENUE FOR YOUR PRACTICE Everyone benefits from using the Theralase laser system; your patient gets better through safe and effective treatments, while your practice generates increased revenue. The graph below shows monthly revenues and return on investment calculations for a TLC-1007H system varying upon the number of treatments delivered per month and the cost per treatment. Revenue per month Monthly Treatments: 200 Cost per Treatment: $45 Payback period of 2 months, Monthly monthly revenue: Revenue: $9,000. $9,000 Annual (Typical ROI: Theralase 514% customer) Monthly Treatments: 300 Cost per Treatment: $65 Monthly Payback period Revenue: of less $19,500 Monthly Treatments: 250 than 1 month, Annual monthly ROI: revenue: 1230% $19,500 Cost per Treatment: $55 Payback Monthly period Revenue: of less $13,750 than 2 months, monthly Annual ROI: revenue: 838% $13,750 REVENUE ($) Payback Monthly period Treatments: of 14 months, 60 monthly Cost per revenue: Treatment: $1,250$25 Monthly Revenue: $1,500 Annual ROI: 2% Number of treatments per Month Payback Monthly perio Treatments: of 3 months, 125 monthly Cost per revenue: Treatment: $5,250 $35 Monthly Revenue: $4,375 Annual ROI: 198% $55 $65 $45 $35 $25 Cost per Treatment ($) Pg.11

CALL TODAY FOR A FREE DEMONSTRATION Experience the Benefits of Theralase TLC-1000 Therapeutic Laser Technology Today WANT MORE INFO? Shah Zarak Khan Managing Director Web: www.theralase.com E-Mail: qssmalaysia@yahoo.com T: (603) 6733 1516 Cell: (6019) 262 1626 F: (603) 6733 1517 Quick Stop Solution Sdn Bhd (895106-X) Unit 4-2, Jalan Desa 9/3, Bandar Country Homes, 48000 Rawang, Selangor Darul Ehsan, Malaysia