How To Treat Bovine Plague

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Diseases and Parasites of Beef Cattle Steven M. Jones Associate Professor - Livestock The University of Arkansas does not endorse any products or services named or pictured in this slide show. University of Arkansas, United States Department of Agriculture and County Governments Cooperating. The Arkansas Cooperative Extension Service offers its programs to all eligible persons regardless of race, color, national origin, religion, gender, age, disability, marital or veteran status, or any other legally protected status, and is an Affirmative Action/Equal Opportunity Employer.

Herd Health Plan Needed to maintain the overall health of the herd Key to success of the plan is the prevention of problems before they start

Vital Signs of Beef Cattle Temp. 100.4-102.8 avg. 101.5 Pulse 60-70 BPM Respiration 10-30 breaths per minute

HEALTHY COWS ARE HAPPY COWS

Diseases

Bovine Spongiform Encephalopathy (BSE): MAD COW DISEASE Chronic, degenerative disease Affects the central nervous system 1 of several brain disease called Transmissible Spongiform Encephalopathy's (TSE s) Some affect animals and some affect humans Other TSE s Chronic Wasting Disease in deer and elk Feline Spongiform Encephalopathy Transmissible Mink Encephalopathy Creutzfeldt-Jakob Disease (CJD- ID in the 1920 s) New variant CJD (nvcjd ID in 1995) Gertsmann-Straussler-Scheinker Syndrome Kuru

BSE in the United States and the World Rare 3 cases in the United States First diagnosed in Great Britain in 1986 The US has not imported any beef from Great Britain since 1985 USDA and the APHIS maintain constant surveillance and enforce import restrictions.

BSE: Symptoms Nervousness or aggression Muscle twitching Abnormal posture Loss of body weight Decrease in milk production Difficulty in rising after lying down Eventual death

So what causes BSE? Not fully known Available evidence indicates that it is not viral or bacterial Related to a prion A prion is a microscopic protein particle that is similar to a virus but lacks nucleic acid BSE may be contracted by ingesting protein in feed that came from an animal source that was contaminated by the agent that causes the disease While no direct link has been made there is suspicion that feeding cattle rendered protein from scrapie infected sheep was involved in spreading the disease In 1997 the FDA banned using ANY mammal derived protein in cattle feed in the United States

Incubation of and Testing for BSE Ranges from 2-8 years Death occurs within 2 weeks to 6 months after clinical symptoms appear No test to determine if live cattle are infected Only a postmortem microscopic examination of the brain can determine if the animal had BSE Brain tissue in infected animals has a spongy appearance when examined under a microscope There is no treatment for BSE

So Can BSE Be Transmitted to Humans? No evidence that it can be transmitted by direct contact or consumption of meat or dairy products No evidence that eating meat of BSE infected animals can cause CJD In 1995 nvcjd was found to be caused by the same agent as BSE but it too was not found in milk or milk only in the brain tissue, spinal cord, corneal tissue and some other central nervous system tissues

BSE

Bovine Virus Diarrhea (BVD) Common throughout the United States May appear in mild, acute & chronic forms Spreads by contact

Mild BVD Often no symptoms If they are present: Fever Coughing Discharge from the nose Slow gains Rapid breathing Mild diarrhea Animals that have had the mild form of the disease are immune to further infection.

Acute BVD Fever Difficult breathing Discharges from the nose and mouth Possible lameness Dehydration Weight loss Diarrhea after 3-7 days Pregnant animals may abort if the disease is contracted with in the first 2 months of pregnancy Fetus s may mummify if contracted from the 90-120 th day of pregnancy Fetus may suffer in later stages of pregnancy Brain damage Hairlessness Underdeveloped lungs

Chronic BVD All the same symptoms as the acute plus Slow gains Rough hair coat Lameness

Preventing BVD Modified live virus vaccine used Calves are vaccinated between 1 day of age and 3 weeks before weaning May be vaccinated when upon arrival in the feedlot They should not be vaccinated at the feedlot if they were vaccinated as calves Pregnant cattle should not be vaccinated Adult cattle should only be vaccinated After calving At least 3 weeks before breeding 1 vaccination will give immunity for the productive life of the animal Replacement heifers should be vaccinated between 9 & 12 months of age but not during the last 3 weeks before breeding There is no cure for BVD

Brucellosis Caused by microorganisms Causes heavy economic losses Less common than it once was due to state and federal eradication programs SD still has brucellosis due to Ted Turner s buffalo near Pierre Dangerous to humans the germs that cause brucellosis cause undulant (Malta) fever

Brucellosis: Symptoms Cattle abort during the last ½ of pregnancy Infected cows retain the afterbirth (placenta) Sterility in cows and bulls Reduced milk flow in cows Enlarged testicles in bulls Calves born to infected cows may be weak

How Brucellosis Spreads Bringing infected cattle into the herd Fence line contact with infected animals Aborted fetus s that carry the Brucella organism being carried to other farms by dogs and other carnivorous animals Calves being infected by their mothers Cattle coming in contact with feed or water where the organism is present Sniffing or licking an aborted fetus or calf from a cow that has the disease

Prevention and Cure No cure Prevention is accomplished by good herd management

Blackleg Caused by bacteria that grow only in the absence of oxygen Most serious when the bacteria lodge in deep wounds When exposed to air the bacteria form a spore and may live in the soil for many years Spores enter the animal through the mouth or wounds Young animals are more commonly affected Malignant Edema has the same symptoms.

Symptoms of Blackleg First sign is one or more animals suddenly die Before death symptoms are: Lameness Swollen muscles Severe depression High fever (in early stages) Animal may be unable to stand

Preventing Blackleg Vaccination Calves are vaccinated when young (typically in the spring at branding or shortly after calving) and again at weaning (fall) Dead animals should be burned or buried

Treating Blackleg Massive doses of antibiotics Treatment is only effective if diagnosed early Prevention is more effective and less costly. Malignant Edema is controlled and treated the same way.

Calf Enteritis (Scours) Disease complex (group of diseases) Most common in fall, winter and spring Afflicts young calves-calves over 2 months of age are seldom affected

Symptoms of Scours Vary Acute form Calf is in a state of shock Nose, ears and legs are cold Diarrhea Sudden death Chronic form Symptoms for several days Weight loss Death after several days if not treated

Preventing Scours Sanitation is the most important factor! Clean barns Clean buckets for bucket calves Calves need the first milk (colostrums) Supplement the cows diet with Vitamin A before calving Most common types of scours can be controlled by vaccines The dam is vaccinated at least 30 days before calving and passes the antibodies on to her calf

Treating Scours Antibiotics Sulfa drugs

Foot Rot Caused by a variety of bacteria, fungi and other organisms found in feedlots They enter the body when the skin of the foot is broken Typically by sharp objects such as stones, nails, or wire Muddy, manure filled feedlots only increase the problem

Symptoms of Foot Rot First noticeable sign is lameness Other symptoms Loss of appetite Fever Depression Animals may not want to stand or move around Death may eventually result

Prevention No vaccine Sanitation and paved lots work best Good drainage and mounds in the feedlot also help in eliminating conditions that encourage the disease. Spreading line and 5% blue vitriol around water tanks and feed bunks help in control.

Treatment Penicillin Wide spectrum antibiotics Sulfa drugs

Pinkeye (Infectious Keratitis, Keratoconjunctivitis) Carried by insects Affects the eye of the animal A viral form of pink eye is associated with IBR

Mild Pinkeye Eyeball develops a pinkish color Cornea becomes slightly clouded

Acute Pinkeye Flowing of tears Cloudiness of cornea As the infection progresses the cloudy condition becomes worse and ulcers may develop on the eye The eye may become so damaged that blindness results The condition may last 3-4 weeks and if not treated will spread to the whole heard

Pinkeye White faced cattle and those with pink skin pigment around the eye are more likely to be infected Pinkeye occurs year round but is most common during periods of maximum sunlight.

How Pinkeye Spreads Insects Direct Contact with infected animals Dust Tail switching

Controlling Pinkeye Control flies and insects to prevent pinkeye Vaccinations are available to control Moraxella bovis, the bacteria that is considered to be the main cause of pinkeye

Treating Pinkeye Animals should be isolated in a dark place Antibiotics and sulfa drugs are applied to the eye Medicine should be applied 2 X s/day Why??? A cloth patch can be used on the affected eye

Shipping Fever (PI3 Pasteurella, Bovine Respiratory Disease) A disease complex that affects the respiratory tract Most common in young cattle at times of stress

Stresses Moving cattle from range to the feedlot Extremes of heat or cold Exhaust fumes Hunger Fright Rough handling All these things allow bacteria and organisms already present to attack the respiratory tract

Symptoms Vary from mild to acute Early symptom is fever Animal appears depressed with it s head down and eyes closed Drooping ears Discharge from the nose Watery eyes Loss of appetite Diarrhea Weight loss Difficult breathing Coughing Pneumonia Possibly death If the animal recovers it will be slow to gain

Preventing Shipping Fever Vaccination may be used. Vaccination should occur after 4 mo. of age The best time to vaccinate is 3-4 weeks before the animal is exposed to the conditions that lead to the disease Reducing stress and exposure also help in prevention Good feedlot management and careful handling of new cattle helps reduce shipping fever.

Treatment of Shipping Fever Antibiotics Sulfa drugs Treatment must begin as soon as symptoms are noticed Treatment after an animal has developed pneumonia is of little value.

Trichomoniasis A venereal disease caused by a protozoan, Trichomona fetus The organism infects the genital tract of the bull and is transmitted to the cow during breeding Clean bulls can also be infected by breeding dirty cows The disease can also be transmitted through infected semen, even when artificial insemination is used.

Symptoms Abortion in early gestation Low fertility Irregular heat periods Uterine infection Cows may have discharge from their genital tract Bulls may not show any symptoms of the disease but still be capable of transmitting it to the cow during breeding The organism is identified by microscopic examination of material from an aborted fetus, the prepuital cavity of the bull or vaginal discharge from the cow

Prevention No treatment or vaccination for trich Infected bulls should be slaughtered Use only clean bulls on clean cows Test bulls to ensure they are free of the disease Use semen from clean bulls

Campylobacteriosis (Vibriosis) Reproductive disease Both intestinal and venereal Leading cause of infertility and abortion in the cattle industry

Campylobacteriosis Intestinal form has little harmful effect Venereal form is more serious If the organism infects the uterus there will be some abortion in the herd Number of cows infected is usually small Cows do not become sterile and bulls are not affected.

Symptoms Infertility Abortion Irregular heat periods In newly affected herds conception rates may drop below 40% Calving season is longer More open cows in the fall In chronically infected herds Conception rate is lower than normal-about 60-70% Heifers or new additions will require repeat breeding or will abort

Prevention and Treatment Vaccinate animals 30 days prior to breeding Vaccination must be repeated every year The disease is spread from infected bulls to clean cows Bulls may be treated with antibiotics but the process is difficult Cows may settle easier if treated with antibiotics Skipping two heat cycles before attempting to breed the cow usually improves the conception rate of infected cows Cows with the disease eventually develop immunity and will breed again The use of AI helps in prevention because the semen used for AI is treated with antibiotics to eliminate disease organisms.

Ringworm A contagious skin disease that can be spread to other animals and humans Symptoms Round, scaly patches of skin that lack hair May appear on any part of the body The affected area clears up but moves to another part of the body Sanitation helps control ringworm Isolate infected animals Treat ringworm with iodine tincture or quaternary ammonium compounds

Ringworm

Nutritional Health Problems (X)

Bloat Occurs when rapid fermentation in the rumen causes to much gas to be produced The rumen swells and the animal can not get rid of the gas

Bloat The major cause of bloat is eating to much green legume too fast Ways to prevent bloat Prevent animals from eating to much legume Feed grain, dry roughage or silage before turning animals onto legume pastures Free access to water should be provided at all times

Bloat Treatments Stomach tubes Walking the animal on rough ground and forcing it to burp Forcing the animal to drink mineral oil or poloxalene (trade name Bloat Guard) Inserting a trocar and cannula into the rumen through the side This should only be considered after other methods have failed.

Enterotoxaemia (Overeating Disease) Usually affects cattle on high-concentrate rations Symptoms Lameness Bloody diarrhea Bloat The animal may die in 1-24 hours Vaccinating calves 2 weeks before putting them on high concentrate rations helps prevent overeating disease Treatments Removing concentrates from the diet Feeding roughage Vaccinating Animals may gradually be put back on the high concentrate ration after vaccination.

Founder A swelling of the tissue that attaches the hoof to the foot Occurs among cattle in the feedlot Caused by Overeating concentrates Sudden change in ration Drinking to much water Standing in a stall for long periods of time Signs Lameness Animal shifts its weight from one foot to another Difficulty in standing Treatment Taking the animal off it s high concentrate diet Putting wet cold packs on the affected parts Antihistamines are sometimes used

Grass Tetany Found most often in cattle during the lactation period It may also be found in cattle that are not lactating Occurs when cattle are grazing pastures that are deficient in magnesium

Symptoms Early signs Excitement Loss of coordination Loss of appetite Other signs Trembling muscles Convulsions Coma Inability to stand Death can occur quickly sometimes within 30 minutes Animals seldom recover if not treated within 8-12 hours

Prevention Feeding magnesium in the ration Especially in areas where there is a soil deficiency Including legumes in the pasture mix

Treatment Injecting a calcium and magnesium solution into the jugular vein Cattle with the disease MUST be handled carefully as stress will kill them. Call a vet when grass tetany is suspected. See fig 17-8 p. 351

Hardware Disease (Traumatic Gastritis) Cattle sometimes pick up sharp metal objects which collect in the reticulum When they are sharp they may puncture the wall of the reticulum causing infection or damage to surrounding organs such as the heart

Symptoms Loss of appetite Arched back Fever Stiffness in moving Less chewing of the cud Pain in defecating Pain in lying down and getting up Flabby brisket Bloat

Prevention and Treatment Prevention Ensuring metal objects do not accidentally become mixed in feed Keeping loose wire, nails, and other sharp objects cleaned up in areas where cattle are Magnets may be placed in the cows stomach to attract and hold the metal The disease is cured surgically.

Summary cont Insecticides are used to control insects flies, lice, mites and ticks are the most common. Sanitation is the most effective control for internal parasites. Roundworms, flatworms, coccidia, anaplasma are the most common. Stomach worms are the most serious. Good management and feeding programs help prevent nutritional health problems