H1N1 Vaccine Deployment and Vaccination update
Outline Donor Commitments Vaccine Prequalification Country Preparedness Vaccine Deliveries Vaccine utilization and coverage Some lessons learned 2 H1N1 Pandemic Vaccine Deployment and Vaccination update
Vaccine Deliveries, by Donor Norway, 1% Belgium, 2% CSL, 2% Switzerland, 2% GSK, 31% Italy, 3% UK, 4% Australia, 5% USA, 21% Sanofi Pasteur, 14% France, 15% 3 H1N1 Pandemic Vaccine Deployment and Vaccination update
Donor Commitments: Finances 70 60 50 USD, millions 40 30 20 10 0 Pledged Committed 4 H1N1 Pandemic Vaccine Deployment and Vaccination update
Donor Commitments: Vaccines 250 200 Millions of doses 150 100 50 0 Pledged Committed Note: Not all commi,ed vaccine became immediately available for delivery 5 H1N1 Pandemic Vaccine Deployment and Vaccination update
Vaccine Prequalification Pandemic Influenza A (H1N1) vaccines prequalified by WHO 01/10/2006 October 2010 31/08/2006 September 01/08/2006 2010 August 01/07/2006 2010 01/06/2006 July 2010 01/05/2006 June 2010 01/04/2006 May 2010 01/03/2006 April 2010 30/01/2006 March 2010 30/12/2005 February 2010 30/11/2005 January 2010 30/10/2005 December 30/09/2005 2009 November 2009 0 1 2 3 4 5 6 7 8 9 10 11 October 2009 Cumula&ve number of vaccines PrequalificaBon date Submission date 6 H1N1 Pandemic Vaccine Deployment and Vaccination update
Recipient Country Preparation: Summary 40 35 30 Number of countries fulfilling pre-supply requirements 07 Jan. 2010: First vaccine delivery 25 20 15 10 5 0 Letter of Intent Letter Agreement National Deployment Plan 7 H1N1 Pandemic Vaccine Deployment and Vaccination update
Vaccine Deliveries, monthly 25 20 15 April 2010: Icelandic volcano disrupts shipment 25,000,000 20,000,000 Number of deliveries 15 10 5 15,000,000 10,000,000 5,000,000 Vaccine doses 0 0 Deliveries 8 H1N1 Pandemic Vaccine Deployment and Vaccination update Volume delivered
9 H1N1 Pandemic Vaccine Deployment and Vaccination update
H1N1 Vaccine Utilization and Coverage by Region Region Vaccine Utilization by H1N1 target population* Vaccine Coverage by general population Range Average Range Average Range Average AFRO 2-100% 61% 4-110% 65% 0.4-11% 4% AMRO 10-100% 64% 1-115% 94% 0.1-48% 24% EMRO 0 82% 15% 0-47% 6% 0-8% 0.6% EURO** 0.2% - 95% 57% n/a n/a 0.01-19% 4% SEARO 25-77% 73% 25-74% 72% 3-7% 7% WPRO 6-100% 53% 39-100% 64% 0.4-87% 8% Overall vaccination coverage in entire population in countries received vaccine from WHO: 6% Overall vaccination coverage in entire population at global level (exclude data from EUR countries under VENICE survey): 12 % Planned target population group as defined by country which is not necessary represent actual target population in the country ** Only data from 6 WHO eligible countries 10 H1N1 Pandemic Vaccine Deployment and Vaccination update
% Vaccine Coverage by H1N1 target group population and entire population in African Region (n = 21) Togo Central African Liberia Guinea Gambia Niger Ethiopia Namibia Zimbabwe Kenya Sao Tome Principé Cameroon Congo Lesotho Seychelles Madagasgar South Africa Equatorial Guinea Sierra Leone Mauritania Mauritius Mean: coverage by H1N1 target population : 65% Mean: coverage by entire population : 4% Vaccination coverage rate per H1N1 target population Vaccination coverage rate per entire population 0 10 20 30 40 50 60 70 80 90 100 % Source: H1N1 Pandemic Vaccine Deployment and Vaccination survey and termination reports 11 H1N1 Pandemic Vaccine Deployment and Vaccination update
%Vaccine Coverage by H1N1 target group population and entire population in American Region (n = 30) El Salvador Guatemala Cuba Paraguay Bolivia Chile Honduras Guyana Nicaragua Suriname Argentina Colombia Ecaudor Brazil Mexico Costa Rica Panama Montserrat Uruguay Peru Turks Trinidad and Tobago USA Bermuda Barbados Bahamas Grenada Belize Mean: coverage by H1N1 target population= 94% Mean: coverage by entire population = 24% Vaccination coverage by H1N1 target group population Vaccination coverage rate per entire country population 0 10 20 30 40 50 60 70 80 90 100 % Source: H1N1 Pandemic Vaccine Deployment and Vaccination survey and regional report 12 H1N1 Pandemic Vaccine Deployment and Vaccination update
%Vaccine Coverage by H1N1 target group population and entire population in Eastern Mediterranean Region (n = 18) Coverage is 0.0% for Pakistan, Somalia and Sudan 13 H1N1 Pandemic Vaccine Deployment and Vaccination update
%Vaccine Utilization and Coverage by entire population in European Region (n = 6: only countries receiving vaccine from WHO) Armenia Moldova Tajikistan Azerbaijan Mean: Vaccine utilization = 57% Mean: coverage by entire population = 4% Georgia Kosovo Utilization rate: countries received WHO donated vaccine Vaccination coverage by entire population 0 10 20 30 40 50 60 70 80 90 100 % Source: H1N1 Pandemic Vaccine Deployment and Vaccination survey and regional report 14 H1N1 Pandemic Vaccine Deployment and Vaccination update
%Vaccine Coverage by H1N1 target group population and entire population in South East Asia Region (n = 7) Bangladesh DPRK Sri Lanka Timor Leste Mean: coverage by entire population = 6% Maldives Bhutan Thailand Vaccination coverage by H1N1 target group population Vaccination coverage by entire population 0 10 20 30 40 50 60 70 80 90 100 % Source: H1N1 Pandemic Vaccine Deployment and Vaccination survey, and regional vaccination report 15 H1N1 Pandemic Vaccine Deployment and Vaccination update
%Vaccine Coverage by H1N1 target group population and entire population in Western Pacific Region (n=26) Vanautu Kiribati Samoa Nauru Fiji Tokelau Cambodia Tonga Cook Islands Mongolia Solomon Islands Tuvalu Lao PDR Papau New Guinea Niue Philippines Republic Korea Marshall Islands Brunei Darussalum Japan Palau China Malaysia New Caledonia New Zealand Mean: coverage by H1N1 target population= 64% Mean: coverage by entire population = 8% Vaccination coverage by H1N1 target group population Vaccination coverage by entire population 0 10 20 30 40 50 60 70 80 90 100 Source: WPRO H1N1 Pandemic Vaccine Deployment and Vaccination Monthly Update: February 2011, Country H1N1 vaccination termination reports % 16 H1N1 Pandemic Vaccine Deployment and Vaccination update
% H1N1 Vaccination Uptake by H1N1 Target Group* Region Health care workers Pregnant women Persons with underlying Conditions Children Country % Uptake* Country %Uptake* Country %Uptake* Country % Uptake* AFRO 17/17 84% 17/17 48% 14/17 66% 11/17 96% AMRO 23/23 100% 23/23 67% 18/23 119% n/a n/a EMRO 6/6 52% 4/6 7% 5/6 21% 4/6 2% EURO** 6/6 62% 4/6 42% 3/6 67% 1/6 61% SEARO 6/6 95% 6/6 86% 6/6 73% 5/6 42% WPRO 9/9 86% 9/9 63% 8/9 85% 5/9 89% * Uptake = doses administered in each target group per planned H1N1 target group population which may not be actual target population **Data from countries receiving donated vaccine from WHO 17 H1N1 Pandemic Vaccine Deployment and Vaccination update
Main Operational Lessons Learned Country plans must be tailored to specific contextual issues. Maintaining global and country communication channels is critical. Countries suggested more emphasis on social mobilization and communication. Global operational readiness and training needed as well as country readiness. H1N1 vaccination public announcement in Tonga 18 H1N1 Pandemic Vaccine Deployment and Vaccination update
Main Operational Lessons Learned Legal framework of agreements should be maintained. A harmonized regulatory process across recipient countries could be useful. Cold chain capacity, global and country, may not be sufficient for future emergencies. Bundling of ancillary equipment remains crucial. H1N1 vaccination vaccine off load in Abuja, Nigeria 19 H1N1 Pandemic Vaccine Deployment and Vaccination update
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