BIOSYNTM BIOSYN TM SUTURE SUTURE

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BIOSYN BIOSYN SUTURE SUTURE

BIOSYN SUTURE Description Characteristics Indications Contraindications Actions Tensile Strength Absorption Sterilization Packaging BIOSYN synthetic absorbable sutures are prepared from a synthetic polyester, GLYCOER 631, composed of glycolide (60%), dioxanone (14%) and trimethylene carbonate (26%). The adanced extrusion process of the molecule of GYLCOER 631 gies the suture: Excellent initial strength Excellent in-io strength oer the critical wound healing period Excellent knot security inimal memory for handling ease BIOSYN synthetic absorbable sutures are indicated for use in general soft tissue approximation and/or ligation including use in ophthalmic surgery, but not for use in cardioascular or neurological surgery. This suture, being absorbable, should not be used where extended approximation of tissue is required. BIOSYN synthetic absorbable sutures elicit a minimal acute inflammatory reaction in tissues, followed by gradual encapsulation of the suture by fibrous connectie tissue. Progressie loss of tensile strength and eentual absorption of BIOSYN synthetic absorbable sutures occurs by means of hydrolysis, where the suture is broken down to glycolic acid, dioxanoic acid, propane diol and carbon dioxide which are subsequently absorbed and metabolized by the body. Subcutaneous tissue implantation studies in rats indicate tensile strength for BIOSYN synthetic absorbable sutures is approximately 75% of and EP minimum knot strength at two weeks and approximately 40% at three weeks post-implant. Absorption begins as a loss of tensile strength without appreciable loss of mass. Absorption of BIOSYN synthetic absorbable sutures is essentially complete between 90 and 110 days. Ethylene oxide BIOSYN synthetic absorbable sutures are aailable in and EP sizes 1 (4 metric) through 6-0 (0.7 metric). They are aailable undyed (natural) or dyed (iolet). The sutures are supplied sterile, in pre-cut lengths or ligating reels; non-needled or affixed to arious needle types, using both permanent and remoable needle attachment techniques; in one, two or three dozen boxes. www.coidien.com/syneture

NON-NEEDLE PRODUCTS PRE-CUT 3x18 Violet 36-72 -74-75 6x18 Undyed 24-23 6x18 Violet 24-31 -32-33 REVERSE CUTTING 19mm 30 Undyed 36 S-690 S-691 S-822 30 Undyed 12 S-691-G S-822-G 30 Violet 36 S-791 S-922 C-13 24mm 30 Undyed 36 S-693 S-823 30 Undyed 12 S-693-G S-823-G 30 Violet 36 S-923 C-14 24mm 5x18 Violet 12 S-83-5x18 Undyed 12 S-93-30 Violet 36 S-633 S-632 C-23 D DERAX NEEDLE SURGALLOY NEEDLE REOVABLE NEEDLES www.coidien.com/syneture SA-1

REVERSE CUTTING 26mm 30 Violet 36 C-879 GS-10 30 Undyed 36 C-543 C-544 30 Violet 36 C-816 C-817 GS-11 36 Violet 36 C-222 GS-13 30 Violet 36 C-528 HOS-11 SA-2 D DERAX NEEDLE SURGALLOY NEEDLE REOVABLE NEEDLES www.coidien.com/syneture

REVERSE CUTTING 40mm 5x18 Violet 12 C-81- HOS-12 PREIU REVERSE CUTTING 11mm 18 Undyed 12 S-3625 S-3626 P-10 13mm 18 Undyed 12 S-5688 S-5687 S-5690 P-13 19mm 18 Undyed 12 S-5624 S-5627 S-5628 30 Undyed 12 S-5637 S-5638 P-12 D DERAX NEEDLE SURGALLOY NEEDLE REOVABLE NEEDLES www.coidien.com/syneture SA-3

PREIU REVERSE CUTTING 24mm 18 Undyed 24 S-5679 30 Undyed 36 S-5678 30 Undyed 12 S-5679-G P-14 PREIU X-CUTTING 13mm D 18 Undyed 12 X-834 DX-13 16mm D 18 Undyed 12 X-845 DX-16 19mm D D 18 Undyed 12 X-822 X-823 DX-19 CONVENTIONAL CUTTING 11mm 18 Undyed 24 C-401 C-400 PC-13 CUTTING Straight 60mm 30 Undyed 36 S-644 S-643 SC-2 SA-4 D DERAX NEEDLE SURGALLOY NEEDLE REOVABLE NEEDLES www.coidien.com/syneture

TAPER POINT 13mm 30 Violet 36 C-126 CV-11 13mm 30 Violet 36 U-986 G-875 30 Undyed 36 U-886 CV-22 17mm 30 Violet 36 U-403 CUTTING 17mm CV-23 30 Violet 36 U-201 U-202 U-203 U-204 30 Undyed 36 U-213 U-214 U-215 CV-23 D DERAX NEEDLE SURGALLOY NEEDLE REOVABLE NEEDLES www.coidien.com/syneture SA-5

TAPER POINT 22mm 30 Violet 36 G-281 36 Violet 36 G-291 G-282 CV-25 22mm 5x18 Violet 12 G-34-30 Violet 36 G-181 G-324 G-183 5x30 Violet 12 G-181- CV-25 12mm 18 Undyed 36 S-432 S-431 CVF-21 27mm 30 Violet 36 C-882 C-883 C-884 C-832 30 Undyed 36 C-830 C-831 GS-22 5x18 Violet 12 C-9- C-10- C-11-5x18 Undyed 12 C-14-30 Violet 36 C-810 C-811 C-812 C-813 30 Undyed 36 C-842 C-843 C-844 C-845 36 Violet 36 C-922 C-923 C-924 C-925 GS-21 36 Undyed 36 C-952 C-953 C-954 SA-6 D DERAX NEEDLE SURGALLOY NEEDLE REOVABLE NEEDLES www.coidien.com/syneture

TAPER POINT 40mm 60 30 Violet 12 C-965-L C-967-L GS-24 40mm 30 Violet 36 C-801 36 Violet 36 C-914 C-966 36 Undyed 36 C-964 GS-24 60 30 Violet 12 C-690-L C-976-L 60 30 Undyed 12 C-990-L GS-25 5x18 Violet 12 C-30- C-31-36 Violet 36 C-903 C-904 C-905 36 Undyed 36 C-974 C-975 GS-25 65mm 60 30 Violet 12 C-679-L 60 30 Undyed 12 C-979-L 96 48 Violet 12 C-680-L 96 48 Undyed 12 C-980-L GS-26 D DERAX NEEDLE SURGALLOY NEEDLE REOVABLE NEEDLES www.coidien.com/syneture SA-7

TAPER POINT 5/8 Circle 26mm 27mm 30 Violet 36 C-558 V-20 GU-46 26mm 5x18 Violet 12 G-64- G-63-5x18 Undyed 12 G-69-30 Undyed 36 G-321 G-322 G-323 30 Violet 36 G-121 G-122 G-123 5x30 Violet 12 G-67-36 Violet 36 G-125 V-20 26mm 30 Violet 36 G-421 36 Violet 36 G-432 G-332 V-20 30mm 30 Violet 36 G-222 G-223 36 Violet 36 G-326 G-327 V-30 SA-8 D DERAX NEEDLE SURGALLOY NEEDLE REOVABLE NEEDLES www.coidien.com/syneture

TAPER POINT 30 Undyed 36 G-226 G-227 V-26 5/8 Circle 27mm 30 Violet 36 U-808 U-879 U-878 U-877 30 Undyed 36 U-979 U-978 U-977 GU-46 5/8 Circle 30 Violet 36 U-243 GU-45 5/8 Circle 30 Violet 36 U-245 U-246 30 Undyed 36 U-345 U-346 GU-45 D DERAX NEEDLE SURGALLOY NEEDLE REOVABLE NEEDLES www.coidien.com/syneture SA-9

BLUNT POINT 5x18 Violet 12 C-740- C-741-36 Violet 36 C-957 BGS-21 40mm 36 Violet 36 C-951 BGS-24 60 30 Violet 12 C-989-L C-988-L BGS-25 5x18 Violet 12 C-949- BGS-25 POINT 26mm 1/2CIRCLE 26 mm BTV-20 BTV-20 30 Undyed 36 GT-226 BTV-20 BLUNT TAPER 1/2 26 mm BTV-20 BLUNT TAPER 1/2 26 mm BTV-20 Fungible Format POINT 1/2 26 mm ϒ 170 R. =.333" Wire Dia..028 3/5/04 Created V-20. from BTV-20.333" SA-10 D DERAX NEEDLE SURGALLOY NEEDLE REOVABLE NEEDLES www.coidien.com/syneture www.coidien.com/syneture 170ϒ

POINT 1/2CIRCLE 37 mm BTP-1 5x18 Violet 12 CT-740- CT-741- BTP-1 BTP-1 Fungible Format POINT 30 Violet 36 1/2 CT-811 37 mm ϒ 180 R. = CT-812.451" Wire Dia..039 3/5/04 Created from BGS- 36 Undyed 36 CT-952 CT-967 CT-845 1/2 37 mm BTP-1 1/2CIRCLE 48 mm 5x18 Violet 12 CT-950- CT-949-36 Undyed 36 Fungible Format POINT 1/2 48 mm ϒ 165 R. CT-974 =.630" Wire Dia..050 3/5/04 Created from BGS- 1/2 48 mm 60 30 Violet 36 CT-989-L 1/2 48 mm BGS-25 Fungible Format POINT 1/2 48 mm ϒ 165 R. =.630" Wire Dia..050 3/5/04 Created from BGS-25 65mm BGST-29 96 48 Undyed 12 CT-890-L 30" 75 cm LOOP 1/2 48 mm 1/2 48 mm BGS-25.NONE (FUN3) TAPERCUTTING 30" 75 30" cm 75 cm LOOP LOOP 60 30 Violet 24 C-940-L 1/2 48 mm KV-40 30" 75 cm LOOP D DERAX NEEDLE SURGALLOY NEEDLE REOVABLE NEEDLES 1/2 48 mm www.coidien.com/syneture SA-11