List of Ingredient Groups under Active Review by CIR July 1, 2010



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1 List of Ingredient Groups under Active Review by CIR July 1, 2010 Ingredient Group List of Ingredients Status Scheduled for August 2010 Panel Meeting Dicarboxylic Acids Sebacic Acid, Disodium Sebacate Diethyl Sebacate Dibutyl Sebacate Dicapryl/Capryl Sebacate Isostearyl Sebacate Diisopropyl Sebacate Diethylhexyl Sebacate Diisooctyl Sebacate Dihexyldecyl Sebacate Dioctyldodecyl Sebacate Malonic Acid, Diethyl Malonate, Succinic Acid, Sodium Succinate, Disodium Succinate, Dimethyl Succinate, Diethyl Succinate, Diethylhexyl Succinate, Decyl Succinate, Dicapryl Succinate, Dicetearyl Succinate, Glutaric Acid, Dimethyl Glutarate, Diisostearyl Glutarate, Adipic Acid, Dimethyl Adipate, Diethyl Adipate, Diethylhexyl Adipate, Dipropyl Adipate, Dibutyl Adipate, Di-C12-15 Alkyl Adipate, Dicapryl Adipate, Dicetyl Adipate, Diheptylundecyl Adipate, Dihexyl Adipate, Dihexyldecyl Adipate, Diisobutyl Adipate, Diisocetyl Adipate, Diisodecyl Adipate, Tabled by Panel 12/09

2 Methyl Acetate and Simple Alkyl Esters and Related Alcohols Stearyl Heptanoate Trimoniums Diisononyl Adipate, Diisooctyl Adipate, Diisopropyl Adipate, Diisostearyl Adipate, Dioctyldodecyl Adipate Ditridecyl Adipate, Azelaic Acid, Dipotassium Azelate, Disodium Azelate Dodecanedioic Acid Dioctyldodecyl Dodecandioate Diisocetyl Dodecanedioate methyl acetate, propyl acetate, isopropyl acetate, t-butyl acetate, isobutyl acetate, butoxyethyl acetate, nonyl acetate, myristyl acetate, cetyl acetate, stearyl acetate, isostearyl acetate, acetic acid, sodium acetate, potassium acetate, magnesium acetate, calcium acetate, zinc acetate, propyl alcohol, isopropyl alcohol. Stearyl Heptanoate Stearyl Caprylate Stearyl Palmitate Stearyl Stearate Stearyl Behenate Stearyl Olivate Acetyl carnitine Acetyl carnitine HCl Acrylamide/ethyltrimonium chloride acrylate/ethalkonium chloride acrylate copolymer Acrylamidopropyltrimonium chloride/acrylamide copolymer Acrylamidoroyltrimonium chloride/acrylates copolymer Behentrimonium chloride June 2010 Panel; TR issued 7/1/10 June 2010 Panel; TR 7/1/2010 June 2010 Panel; TR 7/1/2010.

Behentrimonium methosulfate Carnitine Carnitine HCl Carnitine hydroxycitrate Carnitine PCA Ceteartrimonium chloride Cetrimonium chloride Cetrimonium bromide. Cetrimonium methosulfate Choline Chloride Cocotrimonium chloride Cocotrimonium methosulfate Cocoylcholine Methosulfate Dodecylhexadecyltrimonium chloride Hydrogenated palmtrimonium chloride Hydrogenated tallowtrimonium chloride Lauroyl ethyltrimonium methosulfate Laurtrimonium bromide Laurtrimonium chloride Myristoyl ethyltrimonium methosulfate Myrtrimonium bromide Octacosatrimonium chloride Octyldodecyltrimonium chloride Palmitoyl ethyltrimonium methosulfate Palmitoyl carnitine Polyquaternium-14 Polyquaternium-28 Polyquaternium-32 Polyquaternium-33 Polyquaternium-37 Polyquaternium-35 Polyquaternium-36 Polyquaternium-45 Polyquaternium-47 Polyquaternium-48 Polyquaternium-53 Polyquaternium-63 Polyquaternium-73 Polyquaternium-91 Soytrimonium chloride Stearoxypropyltrimonium chloride Stearoyl ethyltrimonium methosulfate Steartrimonium bromide Steartrimonium chloride Steartrimonium methosulfate 3

4 Tallowtrimonium chloride C13-14 Isoparaffin C7-8 Isoparaffin, C8-9 Isoparaffin, C9-11 Isoparaffin, C9-12 Isoparaffin, C9-13 Isoparaffin, C9-14 Isoparaffin, C9-16 Isoparaffin, C10-11 Isoparaffin, C10-12 Isoparaffin, C10-13 Isoparaffin, C11-12 Isoparaffin, C11-13 Isoparaffin, C11-14 Isoparaffin, C12-14 Isoparaffin, C12-20 Isoparaffin, C13-14 Isoparaffin, C13-16 Isoparaffin, C18-70 Isoparaffin, C20-40 Isoparaffin, C15-35 Isoparaffin/Isoalkylcycloalkanes Isododecane, Isoeicosane, Isohexadecane, Isooctane SLR 6/23/2010 Triclosan Triclosan SLR 4/23/10 C12-15 Alkyl Benzoate C12-15 Alkyl Benzoate Amyl Benzoate Behenyl Benzoate Butyl Benzoate Butyloctyl Benzoate C16-17 Alkyl Benzoate Ethyl Benzoate Ethylhexyl Benzoate Hexyldecyl Benzoate Isobutyl Benzoate Isopropyl Benzoate Isostearyl Benzoate Lauryl/Myristyl Benzoate Methyl Benzoate Octyldodecyl Benzoate Propyl Benzoate Stearyl Benzoate SLR 6/23/2010

5 Oils (See Separate List) http://www.cir-safety.org/staff_files/oils070110.pdf SLR 4/23/10 Nut Oils (See Separate List) SLR 6/23/10 http://www.cir-safety.org/staff_files/nutoils070110.pdf CAPB almondamidopropyl betaine, apricotamidopropyl betaine, Tabled 4/2010 TAR avocadamidopropyl betaine, babassuamidopropyl betaine, behenamidopropyl betaine, capryl/capramidopropyl betaine, coco/oleamidopropyl betaine, coco/sunfloweramidopropyl betaine, isostearmidopropyl betaine, lauramidopropyl betaine, milkamidopropyl betaine, myristamidopropyl betaine, oatamidopropyl betaine, oleamidopropyl betaine, palmamidopropyl betaine, palmitamidopropyl betaine, palm kernelamiodpropyl betaine, ricinoleamidopropyl betaine, sesamidopropyl betaine, shea butteramidopropyl betaine, stearamidopropyl betaine, tallowamidopropyl betaine, undecyleneamidopropyl betaine, wheat germamidopropyl betaine. Disperse Blue 1 Disperse Blue 1 Panel Reopened 4/10 Caprylyl Glycol Arachidyl Glycol Tabled 6/2010 Pentylene Glycol Cetyl Glycol (1,2-glycols) Hexacosyl Glycol Lauryl Glycol Myristyl Glycol Octacosanyl Glycol Stearyl Glycol Caprylyl Glycol Decylene Glycol Pentylene Glycol 1,2-Butanediol 1,2-Hexanediol C14-18 Glycol C15-18 Glycol

6 Dimethiconol Under Active Review Alkyl PEG Ethers Re-Reviews in preparation C18-30 Glycol C20-30 Glycol dimethiconol arginine, dimethiconol beeswax, dimethiconol behenate, dimethiconol borageate, dimethiconol candelillate, dimethiconol carnaubate, dimethiconol cysteine, dimethiconol dhupa butterate, dimethiconol hydroxystearate, dimethiconol illipe butterate, dimethiconol isostearate, dimethiconol kokum butterate, dimethiconol lactate, dimethiconol meadowfoamate, dimethiconol methionine, dimethiconol mohwa butterate, dimethiconol panthenol, dimethiconol sal butterate, dimethiconol stearate, hydrolyzed collagen PG-propyl dimethiconol, dimethiconol/methylsilanol/silicate crosspolymer, dimethiconol/silica crosspolymer, dimethiconol/silsesquioxane copolymer, dimethiconol/stearyl methicone/phenyl trimethicone copolymer, isopolyglyceryl-3 dimethiconol, trimethylsiloxysilicate/dimethiconol crosspolymer, acrylates/dimethiconol acrylate copolymer, (See Separate List) http://www.cir-safety.org/staff_files/alkylpeg.pdf Tabled 6/2010 June 2010 Panel: TR issued TEA/DEA/MEA Not yet available Rereview; Active Benzoic Acid Sodium Benzoate Benzyl Alcohol Benzoic Acid Sodium Benzoate Benzyl Alcohol Calcium Benzoate Magnesium Benzoate Potassium Benzoate Benzyl Benzoate Scientific Literature Reviews in Preparation June 2010 Panel: Re-open

7 Acrylates/C10-30 Alkyl Acrylate Crosspolymer Silica Dimethyl Silate and Trimethylsiloxysilicate Not yet available Silica Dimethyl Silylate Trimethylsiloxysilicate Trifluoropropyldimethyl/trimethylsiloxysilicate Active Active Chamomile Not yet available Active Ingredient Groups Tabled Isethionates Tabled.