University of Pennsylvania School of Medicine Curriculum Vitae Jennifer F. Culhane, Ph.D., MPH Home Address: Office Address: 4636 Larchwood Avenue Philadelphia, PA 19143 3535 Market Street 8 th Floor Suite 880 Department of Adolescent Medicine Children s Hospital of Philadelphia Philadelphia, PA 19104-4399 Email: culhanej@email.chop.edu Date: March, 2011 Education: 1981-1985 B.A. Mount Holyoke College (Biochemistry) 1991-1993 MPH Temple University (Public Health) 1998 Ph.D. Temple University (Public Health) Faculty Appointments: 2001-2004 Assistant Professor, Department of Obstetrics/Gynecology Thomas Jefferson University, Jefferson Medical College 2002 2008 Associate Professor, Department of Obstetrics/Gynecology Drexel University College of Medicine 2001 Present Research Associate, Population Study Center, Department of Sociology, University of Pennsylvania, Philadelphia, PA 3/2008-Present Adjunct Associate Professor, University of North Carolina at Chapel Hill, Department of Maternal and Fetal Medicine, Chapel Hill, NC 3/2008-11/2009 Senior Investigator, Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, PA 12/2009-Present Associate Professor, Department of Pediatrics, University of Pennsylvania School of Medicine Awards Honors and Memberships in Honorary Societies: 2002 Society for Maternal-Fetal Medicine, Award of Research Excellence, poster presentation: Racial/Ethnic Differences in BV in Pregnancy: The Role of Individual and Contextual-level Maternal Stress, Culhane, JF, Rauh VA, Hogan V, McCollum K, Wadhwa PD. 2005 Committee on Understanding Premature Birth and Assuring Healthy Outcomes, Institute of Medicine. 2006 Drexel University School of Public Health, Certification of recognition for service as Preceptor: Community-Based Master s Project Program, 2005-2006. 1
2006 Drexel University Eighth Annual Research Day, Certificate of recognition for best poster presentation. 2006 American Dietetic Association, Food and Nutrition Conference and Expo, Award of Research Excellence, poster presentation: Postpartum Weight Change Among Urban Minorities and the Efficacy of Nutrition Intervention, Huff D, Mathew L, Culhane JF, McKinney S. 2007 ACOG 55 th Annual Clinical Meeting, Blue Ribbon Abstract Award, poster presentation: Preterm Birth in Philadelphia: An Analysis of Women Enrolled in The Preterm Prevention Project. 2007 Department Faculty Teaching Award, Drexel University College of Medicine, Department of Obstetrics and Gynecology, Division of Perinatal Research. 2007 Award for outstanding contribution to the manuscript review process, American Journal of Obstetrics & Gynecology. 2008 Accepted as a Fellow in the 2008-2009 Class of the Hedwig van Ameringen Executive Leadership in Academic Medicine (ELAM) Program for Women. 2008 Outstanding reviewer recognition for Pharmacoepidemiology and Drug Safety Journal. Memberships in Professional and Scientific Societies Local Societies: Southeastern Pennsylvania Chapter of the March of Dimes National Scientific Committees: National Children s Study Steering Committee 2005 Present. Member, Centers for Disease Control and Prevention, Preconception Health and Health Care Initiative Workgroup, 2005 Present. National Children s Study Human Subjects Working Group, 2007 2008 Local Scientific Committees: Southeastern Pennsylvania Chapter of the March of Dimes Program Services Committee, Co-Chair 2004 Present. Southeastern Pennsylvania Chapter of the March of Dimes Community Grants Program Committee, member 2000-2008; Co-Chair 2000-2005. March of Dimes Pennsylvania Chapter First Advantage Executive Advisory, 2010. 2
Editorial Positions 2007 Grant Reviewer, Health Research Board Centers of Excellence Grants Dublin, Ireland 2000 - Current Reviewer, American Journal of Epidemiology The American Journal of Obstetrics and Gynecology Annals of Internal Medicine Archives of Pediatric and Adolescent Medicine Journal of the American Board of Family Medicine The Journal of the American Dental Association Obstetrics and Gynecology Paediatric and Perinatal Epidemiology Pharmacoepidemiology and Drug Safety Women s Health Issues 2008 Member of the Special Emphasis Panel: Eliminations of Health Disparities through Translation Research, Department of Health and Human Services 2010 Associate Editor, Pharmacoepidemiology and Drug Safety Academic Committees: Major Teaching and Clinical Responsibilities: 2005-2008 Member, Institute for Women s Health and Leadership Research Advisory Committee, Drexel University College of Medicine 2007-2008 Chair, Search Committee Director of Women s Health Research, Drexel University College of Medicine 2007-2008 Member, Department of Obstetrics and Gynecology Research Taskforce, Drexel University College of Medicine 6/2009-Present National Children s Study Executive Steering Committee Doctoral and Master of Public Health Students 2004 Committee Member, Doctoral Dissertation Department of Sociology, University of Pennsylvania Helen Lee The Multiple Contexts of Everyday Infant Care Practices of Inner-City Mothers 2005 Community Preceptor, Master of Public Health Department of Community Health Education, East Stroudsburg University Sarah Ritsko Development of a Self-report Instrument for Assessing Sexually Transmitted Infections 2005 Community Preceptor, Master of Public Health Department of Epidemiology and Biostatistics, Drexel University School of Public Health Ephrem Micaih Perceived Paternal Involvement During Pregnancy 3
Resident and Fellow Mentorship 2006 Community Preceptor, Master of Public Health Department of Community Health Education, East Stroudsburg University Tifanie Hudgin Using the REALM to Assess Literacy in a Population of Low-income Urban Women 2006 Community Preceptor, Master of Public Health Department of Community Health Education, East Stroudsburg University Ben Takyi Exploring the Role of Nativity in the Black/White Gap in Preterm Birth 2006 Committee Member, Master of Science Department of Bioscience and Biotechnology, Drexel University Danielle Huff "Nutrition and Weight Status in the Postpartum Period among Women with a Preterm Birth" 2007 Community Preceptor, Master of Public Health Department of Community Health Education, East Stroudsburg University Leah Muriuki Predictors of Breastfeeding Incidence and Duration Rates among African- Americans Participating in the Preterm Prevention Project in Philadelphia 2008 Community Preceptor, Master of Public Health Department of Community Health Education, East Stroudsburg University Aarthi Moorthy Perceived Barriers to Seeking Dental Care by Women in the Preterm Prevention Project 2008 Committee Member, Doctoral Dissertation Department of Maternal and Child Health University of North Carolina, Chapel Hill Dara Mendez The Effects of Institutional Racism, Perceived Discrimination and Maternal Stress on Preterm Birth 2005-2007 Mentor, publications and research project Resident, Department of Obstetrics and Gynecology, Drexel University College of Medicine. Thaddeus Waters, MD 2006- Present Mentor, publications and research project Resident, Department of Obstetrics and Gynecology, Drexel University College of Medicine. Jeffery Denney, MD 4
2007 Present Mentor, publications and research project Fellow, Department of Neonatology, Children s Hospital of Philadelphia Erika Fitzpatrick Dennis, MD Faculty Mentorship 2000 Present Mentor, publications (see publications) and grant submissions Assistant Professor, University of Pennsylvania School of Medicine, Department of Family Medicine Ian Bennett, PhD, MD Submitted grants: 2005 1R03MH074750-01 (funded) Obstacles to Maternal Depression Care Among Women with Low Literacy, Co-PI (Jennifer Culhane) 2007 1 K23 (funded) Literacy and maternal health; Defining Obstacles to Care, Primary Mentor (Jennifer Culhane) 2004 Present Mentor, publications (see publications) and grant submissions Associate Professor of Pediatrics, Department of Pediatrics, Jefferson Medical College of Thomas Jefferson University Esther K. Chung, MD, MPH Submitted Grants: 2004 RO1 NIH grant, submitted but not funded: Antenatal Factors, Neonatal Cytokines and Pediatric Atopy; Co- I (Jennifer Culhane) 2005 R0-3 NIH grant submitted but not funded: Maternal Cytokine Profiles and the Development of Atopic Disease in Early Childhood; Co-I (Jennifer Culhane) 2004- Present Mentor, publications (see publications) and grant submissions Assistant Professor, Drexel University College of Nursing and Health Sciences Joan Rosen Bloch, PhD, CRNP Submitted Grants: 2009 1 K23 NRR010747-01 (funded) Perinatal Health Disparities Between Foreign-born and US-Born Black Women, Primary Mentor (Jennifer Culhane) Courses Taught 2005- Present Mentor, publications (see publications) and grant submission Associate Professor, Department of Psychology, Drexel University Pamela Geller, PhD Submitted grants: 2005 1R01 submitted but not funded, Antenatal Depression and Anxiety: Effects on Offspring Neurodevelopment, Co-PI (Jennifer Culhane) 2007 Understanding and using Medical Statistics, Columbia University College of Medicine, Department of Obstetrics and Gynecology, Fellows. 2010-2011 SOC 264-401 Poverty, Race and Health, University of Pennsylvania School of Medicine 5
Lectures by Invitation: April 28, 2003 February 26, 2004 April 2, 2004 September 23, 2004 April 13, 2005 May 16, 2005 October 11, 2005 February 17, 2006 June 20, 2006 National Low Income Housing Coalition Housing Policy Conference, Washington, DC. The Role of Housing in Child Health and Well-Being. 2 nd Annual Prematurity Symposium March of Dimes Arizona Chapter, Scottsdale, Arizona. Neighborhood and Personal Stress: Contributors to Preterm Birth? Population Association of America, Boston, Massachusetts. Child Health in Developed Countries: New Methods and Findings. The Alarming Rise in Preterm Births in America: New Biologic and Neighborhood Explanations and Interventions. 2004 Maternal-Child Health Update Conference. West Chester University, West Chester PA. The Social Production of Perinatal Risk: Studying Physiology in Social Context. Public Health Forum, Boston University School of Public Health. The Alarming Rise in Preterm Births in America: New Biologic and Neighborhood Explanations and Interventions. Making Change Happen: Translating Research Into MCH Public Health Practice, Eighteenth Annual National Maternal and Child Health Leadership Conference, University of Illinois at Chicago. Prematurity Prevention; Which Interventions Work/Don t Work to Reduce Racial and Ethnic Disparities. The Joint Conference on Health, Keynote address, Yakima, Washington. Preterm Birth and Neighborhood Stress. 14 th Annual Western Perinatal Research Meeting, The Banff Centre. Population Based Efforts to Prevent Preterm Birth. Maternal and Infant Health in Delaware: Bringing Together the Community, Dover Delaware. Race/Ethnic Disparity in Reproductive Outcomes: Does Neighborhood Context Play a Role. October 19 21, 2006 39 th African Heritage Studies Association National Conference (AHSA), Tampa, Florida. Understanding Health and Well-Being in Africa and its Diasporas. November 4, 2006 January 26-27, 2007 Clinical Research Education Day, University of the Sciences in Philadelphia, PA. Aware for All: The Role Of Women As Clinical Research Participants. 10 th Annual Symposium A Day with the Newborn, Philadelphia, PA. Pathway from Stress to Preterm Birth. 6
May 5 7, 2007 November 13, 2007 April 1 2, 2008 April 7, 2008 April 14-15, 2008 May 1 3, 2008 June 23, 2008 October 2, 2008 October 20, 2008 December 3, 2008 December 5, 2008 March 17, 2009 ACOG 55 th Annual Clinical Meeting. San Diego Convention Center, San Diego, CA. Preterm Birth in Philadelphia: An Analysis of Women Enrolled in The Preterm Prevention Project. March of Dimes Summit, Racial and Ethnic Disparities in Birth Outcomes, Philadelphia, PA. Stress at the Individual and Neighborhood Level and Disparities in Birth Outcomes. Iowa Public Health Conference, Scheman Conference Center, Ames, IA. Communities and Neighborhoods: What Are They Really, and How Can They Influence Health? and Incorporating a Community Perspective Into Your Public Health Consciousness. Lecture at Emory University, Atlanta, GA. Studying Preterm Birth in the Context of the National Children s Study. NICHD Preconception Care Research Workshop, Bethesda, MD. Preliminary Findings from The Interconceptional Care Preterm Prevention Project: Prevalence of Risk Factors and Intervention Participation Rates. 5 th World Vaginitis Conference, Istanbul, Turkey. Longitudinal Trajectory of Bacterial Vaginosis in Post-partum Cohort Implications for Pregnancy Complications. Brigham and Women s Hospital, Boston, MA. Newborn Medicine Grand Rounds. Pathway from Stress to Preterm Birth. Philadelphia Pediatric Dental Health Symposium, Temple University Health System, Philadelphia, PA. Maternal/Child Dental Health Research. Impact of Maternal Dental Disease on the Unborn, Dental Issues Starting in Infancy and the Role of WIC. The Center for Public Health Initiatives and VA CHERP, University of Pennsylvania, PA. Unnatural Causes Exploring Health Inequalities through the PBS Series - When the Bough Breaks Part 2 Special Commentary. Vanderbilt University Medical Center, Institute for Medicine and Public Health, Nashville, TN. National Children s Study. University of Pennsylvania, Minorities in Nursing Organization: 2 nd Annual Red and White Charity Ball, Philadelphia, PA. Keynote Speaker. The Role of Racial Discrimination in Adverse Birth Outcomes. University of North Carolina, Chapel Hill, Chapel Hill, NC. Course - Understanding and Addressing Health Inequities in the United States. Understanding and Addressing Health Disparities and Preterm Birth in theunited States. 7
September 26, 2009 October 9, 2009 February 1, 2010 April 22, 2010 May 20, 2010 May 25, 2010 August 5-6, 2010 September 21, 2010 Seattle Children s Research Institute, Seattle, WA. Seminar: Social Production of Preterm Birth. Children and Adults with Attention Deficit Hyperactivity Disorder (CHADD) Research Symposium, Cleveland, OH. Effects of Environmental Toxicants on Executive Function and Manifestation of AD/HD Symptoms. University of Pennsylvania School of Medicine, Philadelphia, PA. Frontiers Course in Environmental Health Sciences. National Children s Study. 5 th Annual Lancaster General Hospital (LGH) Perinatal Conference A Kalidescope of Perinatal Care, Lancaster, PA. Late Preterm Birth: Trends Causes, Consequences and Interventions for Prevention. XXVII Congreso Nacional De Obstetricia Y Ginecologia, Cali, Columbia, Interconception Care; Late Preterm Birth. Abington Memorial Hospital, Abington, PA Department of Pediatrics Grand Rounds. National Children s Study. The Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD. Disparities in Perinatal Medicine: Focus in Infant Mortality, Stillbirth and Preterm Birth. University of Pennsylvania School of Medicine, Philadelphia, PA. Course #MD301-600 Doctor Patient Relationship Introduction to Communication and Culture. Introduction to West Philadelphia; History, Demographics and Health Statistics. November 24-25, 2010 Clinica y Maternidad Suizo Argentina: Meeting of Obstetrics and Neonatology: A Perinatal Approach, Buenos Aires, Argentina. Epidemiology. December 2, 2010 March of Dimes, King of Prussia, PA. Webinar Racial and Ethnic Disparities in Birth Outcomes. December 15-17, 2010 16 th Annual Maternal and Child Health Epidemiology (MCH EPI) Conference, San Antonio, TX. Challenges to Evidence-Based Health Practice. January 26, 2011 March 3, 2011 National Children s Study Federal Advisory Committee Meeting, Bethesda, MD. Aspects of Provider Based Recruitment. Drexel University School of Medicine Family Planning Research Meeting, Philadelphia, PA. The Use of Birth Control in a Poor Urban Minority Population. 8
Research Publications, peer-reviewed Rosowsky A,Wright JE, Cucchi CA, Flatow JL, Trites DH, Teicher BA, Frie E. Collateral methotrexate resistance in cultured human head and neck carcinoma cells selected for resistance to cis-diamminedichoroplatinum (11). Cancer Research, 1987; 47(22): 5913-8. Wright JE, Rosowsky A, Waxman DJ, Trites DH, Teicher BA, Flatow JL, Frie E. Metabolism of methotrexate and gamma-tert-butyl methotrexate by human leukemic cells in culture and by hepatic aldehyde oxidase in vitro. Biochemical Pharmacology, 1987; 36(13): 2209-1. Teicher BA, Cucchi CA, Lee JB, Flatow JL, Rosowsky A, Frie E. Alkylating agents: In vitro studies of cross-resistance patterns in human cell line. Cancer Research, 1987; 46(9): 4378-9. Teicher BA, Crawford JM, Holden SA, Cathcart KN, Luchette CA, Flatow JL. Glutathione monoethylester can selectively protect liver from high dose BCNU or cyclophosphamide. Cancer, 1988; 62(7): 1275-8 1. Keystone EC, Rittershause C, Wood N, Snow KM, Flatow JL, Purvis JC, Poplonski L, Kung P. Evaluation of gamma delta T-cell subset in peripheral blood and synovial fluid of patients with rheumatoid arthritis. Clinical Experimental Immunology, 1991; 84(l): 78-82. Wright JE, Rosowsky A, Cucchi CA, Flatow JL, Frie E. Methotrexate and gamma-tert-butyl methotrexate transport in CEM and CEM/MTX human leukemic lymphoblasts. Biochemical Pharmacology, 1993; 46(5): 871-6. Culhane D, Culhane JF. The elderly's underutilization of partial hospitalization services and the history of Medicare reimbursement policies. Journal of Geriatric Psychology, 1993; 269(1): 95-112. Haignere C, Culhane JF, Balsley C, Legos P. Sexuality education: Teacher's receptiveness and comfort using non-traditional teaching strategies. Journal of School Health, 1996; 66(4): 125-53. Teicher BA, Holden SA, Cucchi CA, Cathcart KN, Korbut, TT, Flatow JL, Frie E. Combination of N,N,N -triethyenethiophsphomide and cyclophosphamide in vitro and in vivo. Cancer Research, 1998; 48(l): 94-100. Kornhauser MS, Baumgart S, Desi SA, Stanley CW, Culhane JF, Cullen JA, Wiswell-TE, Graziani LT, Spitzer AR. Adverse neurodevelopmental outcomes in infants with 8PD treated with ECMO. Journal of Pediatrics, 1998; 132(2): 307-11. Gibson E, Flemming N, Culhane, JF, Flemming D, Spitzer A. Changes in SIDS rate following the American Academy of Pediatrics sleep position recommendation. Medical Care, 1998; 36(6): 938-42. Gibson E, Culhane JF, Saunders T, Webb D, Greenspan J. Effect of non-viable infants on the infant mortality rate in Philadelphia, 1992. American Journal of Public Health, 1999; 90(8): 1303-6. Rauh VA, Culhane JF, Hogan VK. Bacterial vaginosis: A public health problem for women. JAMWA, 2000; W55(4): 220-4. 9
Webb D, Culhane JF, Snyder S. Pennsylvania's early discharge legislation: Impact on maternity length-of-stays and costs of hospitalization in Philadelphia. Health Services Research, 2001; 36(6pt1): 1073-83. Wadhwa PD, Culhane JF, Rauh, VA, Barve SS, Hogan VK, Sandman CA, Hobel CJ, Dunkel-Schetter C, Garite ZTJ, Glynn L. Stress, infection and preterm birth: A biobehavioral perspective. Pediatric and Perinatal Epidemiology, 2001; 15 suppl 2: 17-29. Wadhwa PD, Culhane JF, Rauh VA, Barve SS. Stress and Preterm. Birth: Neuroendocrine, immune-inflammatory and vascular mechanisms. Maternal and Child Health Journal, 2001; 5(2): 119-25. Culhane JF, Rauh VA, McCollum K, Hogan VK, Agnew K, Wadhwa P. Maternal stress is associated with bacterial vaginosis in human pregnancy. Maternal Child Health Journal, 2001 June; 5(2): 127-34. Culhane JF, Rauh VA, Elo, IT, McCollum KF, Hogan V. Exposure to chronic stress and ethnic differences in rates of bacterial vaginosis among pregnant women. American Journal of Obstetrics and Gynecology, 2002 Nov.; 187(5): 1272-76. Webb D, Culhane JF. Hospital variation in episiotomy use and the risk of severe perineal trauma during childbirth. Birth, 2002 June; 29(2): 132-6. Webb D, Culhane JF. Time of day variation in rates of obstetrical interventions to assist in vaginal deliveries. Journal of Epidemiology and Community Health, 2002; 56(8): 577-8. Culhane JF, Webb D, Grim S, Metraux S, Culhane DP. Prevalence of child welfare services involvement among homeless and low-income mothers: A five-year birth cohort study. Journal of Sociology and Social Welfare, 2003; 30(3): 79-96. Hobel C, Culhane JF. Role of psychosocial stress and nutritional stress on pregnancy outcome. The Journal of Nutrition, 2003; 133(5 Suppl 2): 1709s-17. Webb D, Culhane JF, Metraux S, Culhane DP. Prevalence of episodic homelessness among childbearing women in Philadelphia, PA. American Journal of Public Health, 2003; 93(11): 1895-6. Goldenberg R, Culhane JF. Infection as a cause of preterm birth. Clinics in Perinatology, 2003; 30 (4): 677-700. Chung EK, Culhane JF, Elo I, Rauh VA, Riley T, Farley McCollum K, Rubio M, Lee H. Maternal depressive symptoms and infant health practices among low-income women. Pediatrics, 2004; 113: e523-529. Goldenberg RL, Kirby R, Culhane JF. Stillbirth: A Review. The Journal of Maternal-Fetal & Neonatal Medicine, 2004; 16(2): 79-94. Goldenberg RL, Culhane JF. Prepregnancy health status and the risk of preterm delivery. Archives of Pediatric and Adolescent Medicine, 2005; 159: 89-90. Culhane JF, Davide De Santo, Robert L. Goldenberg, Kelly F. McCollum, Felicia King, Secondo Guaschino. Variation in Nugent Score and Leukocyte Count in Vaginal Fluid Collected from Different Sites. Obstetrics and Gynecology, 2005; 150: 120-123. 10
Pereira L, Culhane JF, McCollum KF. Variation in microbiologic profiles among pregnant women with bacterial vaginosis. American Journal of Obstetrics and Gynecology, 2005; 193(3): 746-51. Culhane JF, Elo IT. Neighborhood context and reproductive health. American Journal of Obstetrics and Gynecology, 2005; (192) s22-9. Lee H, Rubio MR, Elo IT, McCollum KF, Chung E, Culhane, JF. Factors associated with intention to breastfeed among low-income, inner-city pregnant women. Maternal Child Health Journal, 2005; 9(3): 253-61. dupont NC, Wang K, Wadhwa P, Nelson E, Culhane JF. Validation and comparison of luminex multiplex cytokine analysis kits with ELISA: determination of a panel of nine cytokines in clinical sample culture supernatants. Journal of Reproductive Immunology, 2005; 66(2): 175-91. Culhane JF, Nyirjesy P, McCollum K, Goldenberg RL, Gelber SE, Cauci S. Variation in vaginal immune parameters and microbial hydrolytic enzymes in bacterial vaginosis positive pregnant women with and without mobiluncus species. American Journal of Obstetrics and Gynecology, 2006; 195(2): 516-21. Castrucci BC, Culhane JF, McCollum KF, Chung E, Bennett I. Smoking in pregnancy: Patient and provider risk reduction behavior. Journal of Public Health Management and Practice, 2006; 12(1): 68-76. Chung EK, McCollum KF, Elo IT, Culhane JF. Does prenatal care at community-based health centers result in infant primary care at these sites? Ambulatory Pediatrics, 2006; 6(1): 25-31. Bennett IM, Culhane JF, McCollum K. Unintended repeat pregnancy and low educational status: Any role for depression and contraception use? American Journal of Obstetrics and Gynecology, 2006; 194(3): 749-754. Lu MC, Kotelchuck M, Culhane JF, Hobel CJ, Klerman LV, Thorp JM Jr. Preconception care between pregnancies: The content of internatal care. Maternal Child Health J. 2006; Volume 10(5s): S107-22. Messer LC, Kaufman JS, Laraia, BA, Eyster J, Holzman C, Culhane JF, Elo I, Burke JG, O Campo P. The development of a standardized neighborhood deprivation index. Journal of Urban Health, 2006; 83(6): 1041-62. Nyirjesy P, Peyton C, Weitz V, Mathew L, Culhane JF. Causes of chronic vaginitis: Analysis of a prospective database of affected women. Obstetrics and Gynecology, 2006; 108(5) 1185-91. Goldenberg RL, Culhane JF. Preterm birth and periodontal disease. New England Journal of Medicine, 2006; 355(18): 1925-27. Culhane JF, Rauh VR, Goldenberg RL. Stress, bacterial vaginosis and the role of immune processes. Current Infectious Disease Reports, 2006; 8(6): 459-64. Cauci S, Culhane JF. Modulation of vaginal immune response among pregnant women with bacterial vaginosis by Trichomonas vaginalis, Chlamydia trachomatis, Nesisseria gonorrhea, and yeast. American Journal of Obstetrics and Gynecology, 2007; 196(2): 133.e 1-7. 11
Goldenberg RL, Culhane JF. Low birth weight in the United States. American Journal of Clinical Nutrition, 2007; 85(2): 584S-590S. Banda Y, Chapman V, Goldenberg RL, Stringer JSA, Culhane JF, Sinkala M, Vermund SH, Chi BH. Use of traditional medicine among pregnant women in Lusaka, Zambia. Journal of Alternative and Complementary Medicine, 2007; 13(1): 123-8. Chung EK, Miller RL, Wilson MT, McGeady SJ, Culhane JF. Antenatal risk factors, cytokines and the development of atopic disease in early childhood. Archives of Disease in Childhood Fetal and Neonatal Edition,2006; 92:f68-f73. Bennett IM, Culhane JF, McCollum KF, Mathew L, Elo IT. Literacy and depressive symptomatology in pregnancy among Latinas with limited English proficiency. American Journal of Orthopsychiatry, 2007; 77(2): 243-8. Hogan VK, Culhane JF, Hitti J, Rauh VA, McCollum KF, Agnew KJ. Relative performance of three methods for diagnosing bacterial vaginosis during pregnancy. Maternal and Child Health Journal, 2007; 11(6): 532-39. Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet, 2008; 371(9606): 75-84. O Campo P, Burke JG, Culhane JF, Elo IT, Eyster J, Holzman C, Messer LC, Kaufman JS, Laraia BA. Neighborhood deprivation and preterm birth among non-hispanic black and white women in eight geographic areas in the United States. American Journal of Epidemiology, 2008; 167: 155-63. Chung EK, Mathew L, Elo IT, Coyne JC, Culhane JF. Depressive symptoms in disadvantaged women receiving prenatal care: The influence of adverse and positive childhood experiences. Ambulatory Pediatrics, 2008; 8(2): 109-16. Chung EK, Mathew L, McCollum KF, Elo IT, Culhane JF. Continuous source of care among young underserved children: Associated characteristics and parenting practices. Ambulatory Pediatrics, 2008; 8(1): 36-42. Cauci S, Di Santolo M. Culhane JF, Stel G, Gonano F, Guaschino S. Effects of third-generation oral contraceptives on high-sensitivity C-reactive protein and homocysteine in young women. Obstetrics Gynecology, 2008; 111(4):857-64. Cauci S, Culhane JF, Di Santolo M, McCollum K. Among pregnant women with bacterial vaginosis the hydrolytic enzymes, sialidase and prolidase are positively associated with interleukin-1beta. American Journal of Obstetrics Gynecology, 2008; 198(1):132.e1-7. Iams JD, Romero R, Culhane JF, Goldenberg RL. Primary, secondary, and tertiary interventions to reduce the morbidity and mortality of preterm birth. Lancet, 2008; 371(9607): 164-75. Messer LC, Vinikoor L, Laraia BA, Kaufman JS, Eyster J, Holzman, Culhane JF, Elo I, Burke JG, O Campo P. Socioeconomic domains and associations with preterm birth. Social Science and Medicine, 2008; 67(8): 1247-57. Cauci S, Di Santolo M, Culhane JF, Stel G, Gonano F, Guaschino S. Effects of third-generation oral contraceptives on high-sensitivity C-reactive protein and homocysteine in young women. Obstetrics and Gynecology, 2008; 111(4): 857-64. 12
Culhane JF, Nyirjesy P, McCollum K, Casabellata G, DiSantolo M, Cauci S. Evaluation of semen detection in vaginal secretions: Comparison of four methods. American Journal of Reproductive Immunology, 2008; 60(3): 274-81. Chong E, Greenspan J, Kirkby S, Culhane J, Dysart K. Changing use of surfactant over six years and its relationship to chronic lung disease. Pediatrics, 2008; 122(4): e917-21. Bennett IM, Pinder P, Szesniak R, Culhane JF. Take charge of your health: A collaborative health literacy intervention linking adult education and maternal-infant health care, Focus on Basics, 2008; 9(b): 14-20. Waters T, Denney J, Mathew L, Goldenberg R, Culhane J. Longitudinal trajectory of bacterial vaginosis during pregnancy, American Journal of Obstetrics and Gynecology, 2008; 199(4): 431.e1-5. Webb D, Bloch JR, Coyne J, Chung EK, Bennett IM, Culhane JF. Postpartum physical symptoms in new mothers: Their relationship to functional limitations and emotional well-being. Birth, 2008; 35(3): 179-187. Lee H, Elo IT, McCollum KF, Culhane JF. Racial/ethnic differences in breastfeeding initiation and duration among low-income, inner-city mothers. Social Science Quarterly, 2008; 169(1): 24-32. Denney JM, Culhane JF, Goldenberg RL. Prevention of preterm birth. Women s Health, 2008; 4(6): 625-38. Nawab US, Greenspan JS, Kirkby S, Culhane JF, Kornhauser M. Differences in short-term neonatal outcomes between discordant twins. Advances Neonatal Care, 2008; 8(6): 334-342. Agnew K, Aura J, Nunez, Lee Z, Lawler R, Richardson C, Culhane J, Hitti J. Effect of semen on vaginal fluid cytokines and secretory leukocyte protease inhibitor. Infectious Diseases in Obstetrics and Gynecology, 2008; epub ahead of print. Mora Pa, Bennett IM, Elo IT, Mathew L, Coyne JC, Culhane JF. Distinct trajectories of perinatal depressive symptomatology: Evidence from growth mixture modeling. American Journal of Epidemiology, 2009; 169(1): 24-32. Elo IT, Culhane JF, Kohler IV, O Campo P, Burke JGM, Messer LC, Kaufman JS, Laraia BA, Eyster J, Holzman C. Neighborhood deprivation and small-for-gestational-age term births in the United States. Paediatric and Perinatal Epidemiology, 2009; 23(1): 87-96. Denney JM, Culhane JF. Bacterial vagonosis: A problematic infection from both a perinatal and neonatal perspective. Seminars in Fetal & Neonatal Medicine, 2009; 14(4): 200-3. Brandon GD, Adeniyl-Jones S, Kirkby S, Webb D, Culhane J, Greenspan J. Are outcomes and care processes for preterm neonates influenced by health insurance? Pediatrics, 2009; 124(1): 122-7. Chung EK, Mathew L, Rothkopf AC, Elo IT, Coyne JC, Culhane JF. Parenting attitudes and infant spanking: The influence of childhood experiences. Pediatrics, 2009; 124(2): 278-286. Bloch JR, Webb D, Mathew L, Bennett I, Culhane J. Beyond Marital Status: The quality of the motherfather relationship and its influence on reproductive health behaviors and outcomes among unmarried low income pregnant women. Maternal and Child Health, epub ahead of print. 13
Wright JD, Shah M, Mathew L, Burke WM, Culhane J, Goldman N, Schiff PB, Herzog TJ. Fertility preservation in young women with epithelial ovarian cancer. Cancer, 2009; 115(18): 4118-26. Holzman C, Eyster J, Kleyn M, Messer L, Kaufman J, Laraia B, O Campo P, Burke J, Culhane J, Elo I. Maternal Weathering and Risk of Preterm Delivery. American Journal of Public Health, 2009; 99(10): 1864-71. Elo IT, Mykyta L, Margolis R, Culhane JF. Perceptions of neighborhood disorders: The role of individual and neighborhood characteristics. Social Science Quarterly, 2009; 90(5): 1298-1320. Nyirjesy P, Lev-Sagie A, Mathew L, Culhane J. Topical amitripyline-baclofen cream for the treatment of provoked vestibulodynia. Journal of Lower Genital Tract Disease, 2009; 139(4): 230-236. Bennett I, Culhane JF, Webb D, Coyne JC, Hogan V, Mathew L, Elo IT. Perceived discrimination and depressive symptoms, smoking and recent alcohol use in pregnancy. Birth: Issues in Perinatal Care, 2009; 37(2): 90-97. Webb D, Robbins JM, Culhane JF, Elo IT. Estimating prevalence of overweight and obesity at the neighborhood level: The value of maternal height and weight data available on birch certificate records. Population Health Metrics, 2010; 8(16): 1-6. Chung EK, Nurmohamed L, Mathew L, Elo IT, Coyne J, Culhane JF. Risky health behaviors among mothers-to-be: The impact of adverse childhood experiences. Academic Pediatrics 2010; 10:245-51. Webb DA, Coyne JC, Goldenberg RL, Hogan VK, Elo IT, Bloch JR, Mathew L, Bennett IM, Dennis EF, Culhane JF. Recruitment and retention of women in a large randomized control trial to reduce repeat preterm births: The Philadelphia Collaborative Preterm Project. BMC Medical Research Methodology, 2010; 10:88. Elo IT, Culhane JF. Variations in health and health behaviors by nativity among pregnant black women in Philadelphia. American Journal of Public Health, 2010; 100(11): 2185-2192.. Webb D, Culhane JF, Mathew L, Block JR, Goldenberg RL. Incident smoking during pregnancy and in the postpartum period in a low-income urban population. Public Health Reports, 2011; 126(1): 50-9. Research Publications, in press Cauci S, Culhane J. High sialidase levels increase preterm birth risk among bacterial vaginosis positive women in early gestation. American Journal of Obstetrics & Gynecology, in press. Culhane J, Goldenberg RL. Racial disparities in preterm birth. Seminars in Perinatology, in press. Research Publications, under review Dennis EF, Webb DA, Scott LA, Mathew L, Bloch JR, Culhane JF. Subjective social status and maternal health in a urban low income population. Maternal and Child Health, under review. 14
Mendez D, Hogan V, Culhane J. Institutional racism and health: using home mortgage disclosure act data to develop a new index for mortgage discrimination on the community level. Journal of Public Health Reports, under review. Mendez D, Hogan VK, Culhane JF. Preterm birth and role of residential redlining and the perception of stress, discrimination and neighborhood quality among black, white, and hispanic women. Social Science and Medicine, under review. Nyirjesy P, Robinson J, Mathew M, Lev-Sagie A, Reyes I, Culhane JF. Use of alternative therapies in women with chronic vaginitis: Analysis of a prospective database. Obstetrics and Gynecology, under review. Research Publications, peer-reviewed reviews Iams JD, Romero R, Culhane JF, Goldenberg RL. Primary, secondary, and tertiary interventions to reduce the morbidity and mortality of preterm birth. Lancet, 2008; 371(9607): 164-175. Goldenberg RL, Culhane JF, Johnson D. Maternal Infection and adverse fetal and neonatal outcomes. Clinical Perinatology, 2005; 32(2): 523-559. Goldenberg RL, Culhane JF, Iams J, Romero R. Epidemiology and causes of preterm birth. Lancet, 2008; 371: 75-84. Abstracts: Robinson J, Nyirjesy P, Mathew L, Lev-Sagie A, Reyes I, Culhane JF. Predictors for use of alternative therapies in women with chronic vaginal symptoms: Analysis of a prospective database of affected women. Annual Meeting of the Infectious Diseases Society for Obstetrics and Gynecology, Santa Fe, New Mexico. 2010 Poster presentation. Nyirjesy P, Leigh RD, Mathew L, Lev-Sagie A, Culhane JF. Chronic "vaginitis" in women over 50: Analysis of a proscpective database. International Society for the Study of Vulvovaginal Disease, XX World Congress, Edinburgh, Scotland. J Lower Gen Tract Dis, October, 2009, S1. Oral Presentation. Linhares IM, Lev-Sagie A, Nyirjesy P, Mathew L, Sezen D, Culhane J, Witkin SS. Gene Polymorhisms and Vulvovaginal Symptoms. 6 th European Conference of the European Society for Infectious Diseases in Obstetrics and Gynecology (ESIDOG), Leuven, Belgium. August, 2008. Oral Presentation Waters T, Denney J, Mathew L, Goldenberg R, Culhane J. Longitudinal Trajectory of Bacterial Vaginosis During Pregnancy. American Journal of Obstetrics and Gynecology, December, 2007. Poster Presentation. Waters T, Denney J, Mathew L, Goldenberg R, Culhane J. Longitudinal Neonatal Outcomes Among women with Mobiluncus Species on 1 st Trimester Gram Stain. American Journal of Obstetrics and Gynecology. December, 2007. Poster Presentation. 15
Denney J, Waters T, Nelson E, Mathew, Goldenberg R, Culhane J. Longitudinal Modulation of Immune System Cytokine Profile During Pregnancy. American Journal of Obstetrics and Gynecology, December 2007. Oral Presentation. Denney J, Waters T, Mathew L, Brenner M, Culhane J. Preterm Birth in Philadelphia: An Analysis of Women Enrolled in the Preterm Prevention Project. Obstetrics and Gynecology, April 2007; 109:4:95S. Oral Presentation. Chung E, Greenspan JS, Kirkby S, Culhane J, Dysart K. Changing Use of Surfactant Over 6 Years and its Relationship to Chronic Lung Disease, Society for Pediatric Research, 2007, San Francisco. McGovern A, Kirkby S, Greenspan JS, Culhane J, Webb D, Dysart K. The impact of the 5-minute Apgar Score on Infants < 1000 grams, Society for Pediatric Research, 2007, San Francisco. Dysart K, Kirkby S, Culhane J, Miller T, Greenspan JS. The Use of Systemic Corticosteroids in Infants <1000 grams, Society for Pediatric Research, 2007, San Francisco. Kirkby S, Turenne W, Culhane J, Webb D, Adeniyi-Jones S. Complication Rates for Moderate Preterm Infants Born Small for Gestational Age, Society for Pediatric Research, 2007, San Francisco. Adeniyi-Jones S, Webb D, Kirkby S, Culhane J, Greenspan JS. Does Health Insurance Status influence Discharge Care for Preterm Infants with Bronchopulmonary Dysplasia? Society for Pediatric Research, 2007, San Francisco. Waters T, Denney J, Mathew L, Brenner M, Culhane J. C-Reactive Protein and Periodontal Disease at one Month Post-Partum in Women with a Recent Pre-term Birth: Prospective Data from the Preterm Prevention Project. American Journal of Obstetrics and Gynecology, December 2006, Vol. 195 Number 6, 671. Oral Presentation. Denney J, Waters T, Mathew L, Brenner M, Culhane J. Variation in CRP at 1 Month Post-Partum By Etiology of Preterm Birth: Data from the Preterm Prevention Project. American Journal of Obstetrics and Gynecology; December 2006, Vol. 195, Number 6, 721. Oral Presentation. Culhane JF, Nyirjesy P, McCollum K, Casabellata G, Cauci S. Determination of Semen Contamination of Vaginal Secretions: Comparison of Four Different Methods. Poster presentation. Annual Meeting of the Infectious Diseases Society for Obstetrics and Gynecology, 2006, Monterey, Calfornia. Duncan GD, Adeniyi-Jones S, Kirkby S, Webb D, Culhane JF, Greenspan JS. Health Insurance Status and Neonatal Outcomes in Preterm Infants. Society for Pediatric Research, 2006, San Francisco. Duncan GD, Adeniyi-Jones S, Kirkby S, Webb D, Culhane JF, Greenspan JS. Are Care Processes for Preterm Neonates Influenced by Health Insurance Status? Society for Pediatric Research, 2006, San Francisco. McGovern AM, Shobhana D, Greenspan J, Culhane J, Webb D, Kirby S. Risk Profile During the Early Neonatal Period for Developing Severe Retinopathy of Prematurity (ROP) in the Very Low Birthweight Preterm Infant. Society for Pediatric Research, 2006, San Francisco. McGovern AM, Shobhana D, Greenspan JS, Culhane JF, Webb D, Kirby S. Impact of Ethnicity on Retinopathy of Prematurity (ROP). Society for Pediatric Research, 2006, San Francisco. 16
Bennett I, Culhane JF, McCollum KF. Unintended Repeat Pregnancy and Low Educational Status: Any Role for Depression and Contraception Use? Contraception, September 2005. Cook AG, Greenspan JS, Kirby S, Webb D, Culhane JF, Kornhauser M. The Interaction of the Timing of Oral Feed Initiation and the Development of Bronchopulmonary Dysplasia (BPD) in Preterm Infants, Society for Pediatric Research, 2005, San Francisco. Bennett I, Culhane JF. Maternal Depressive Symptomatology Among Non English-Speaking Latinas with Low Literacy in the U.S. Inner City. (poster), The Penn Summit on Global Issues in Women s Health, 2005, Philadelphia, PA. Nyirjesy P, Peyton C, Weitz MV, Culhane JF. Chronic Vaginitis: Initial Results from a Prospective Database. Oral presentation. Annual Meeting of the Infectious Disease Society for Obstetrics and Gynecology, 2005, Charleston, South Carolina. Elo, I.T., Mykyta L, and Culhane JF. Paternal Support and Father-Child Contact: Evidence from a Low- Income, Inner-City Population, Annual Meeting of the Population Association of America, 2005, Philadelphia, PA. Editorials, Reviews, Chapters, including participation in committee reports: Rauh VA Perera F, Culhane JF. In (David Bellinger, Ed) Human Developmental Neurotoxicology. Chapter 19, Incorporating the Social-Ecological Perspective into Studies of Neurodevelopmental Toxicity. Taylor and Francis Group, New York: 393-414, 2006. Behrman Richard E, Butler Stith Adrienne (Editors), Culhane JF (Committee Member). Preterm Birth Causes, Consequences and Prevention. The National Academies Press, Washington, DC, 2007. 17
PAST GRANT SUPPORT NAME Jennifer Culhane DEPARTMENT Pediatrics DATE July, 2009 ----------------------------------------------------------------------------------------------------------------------------- ---------------------------------------------------------- Name of Grant Period of Grant Role in Grant % Effort Funding Source Current Annual Additional Award Category Direct Cost Comments 1. The Philadelphia 6/1/04-5/30/08 (extended 3 mon.) FG PI 7.5% PA State Dept. $1,224,911 Collaborative of Hlth. Ctr. of Preterm Prevention Excellence for Research Project on Pregnancy Outcomes 2. Targeting Programs 9/30/02-9/30/07 FG PI 20% DHS/HRSA $100,000 for Reducing Racial Ethnic and Geographical Health Disparities 3. Reproductive Health 7/10/05-9/9/06 FG PI 15% ATPM/CDC $297,600 Earmarks from the Centers for Disease Control and Prevention 4. Evidence-based Program 9/1/02-8/31/03 R21 Co-PI 10% NICHD $198,125 For the Integration of Curricula 5. Preterm Birth Among 10/1/98-9/30/01 FG PI 25% (ATPM/CDC) $366,666 Inner City Women-BV: Stressors & Race 6. Rethinking Prenatal 10/1/04-9/30/05 PG PI 20% March of Dimes $25,000 Services: Implementing Group Care with an Emphasis on the Social Determinants of Health 18
Name of Grant Period of Grant Role in Grant % Effort Funding Source Current Annual Additional Award Category Direct Cost Comments 7. Biologic Pathways 9/1/00-8/3/05 FG PI 20% ATPM/CDC $323,019 Linking Stress, BVand Preterm Birth 8. Racial and 10/1/99-9/31/05 RO1 Co-PI 30% NICH/NICHD $488,923 Neighborhood Disparities in Infant Health 9. Preterm Birth and Race: 10/1/01-9/30/06 FG PI 10% ATPM//CDC $16,105 A Study of Individual and Spatial Effects 10. Microbial and Immune 10/1/01-9/30/05 FG PI 15% ATPM/CDC $313,365 Parameters Associated With Prematurity 11. Obstacles to Maternal 9/15/05-6/30/07 FG Co-PI 5% NIH/NIMH $50,000 Depression Care Among Women with Low Literacy 12. Eliminating Disparities in 1/1/07-1/31/08 FG PI 5% CDC/National $110,000 Interconceptional Care Healthy Start Assoc. Health Research Study *For Grant Category, use code in bold from the following menu: R01 NIH R01 CT Clinical Trials PP NIH Program Project, Center or Core Grants TG Training Grants FG Federal Grants - Other (including other individual NIH grants IG Industrial Grants (including pharmaceutical) and grants from VA, NSF, Dept. of Energy, etc.) PG Private Foundation Grants (including internal Penn grants) O Other ** For program projects, specify whether PI, co-leader or project leader. For center, core and training grants, similarly specify your role. *** Include any additional, brief information. For clinical trials, for example, specify if multicenter or single center and indicate role of Penn site. Explain any grants in Other category. 19
CURRENT GRANT SUPPORT NAME OF FACULTY MEMBER Jennifer F. Culhane DEPARTMENT Pediatrics DATE July, 2009 ---------------------------------------------------------------------------------------------------------------------------- ------------------------------------------------------------- Name of Grant Period of Grant Role in Grant % Effort Funding Source Annual Additional Award Category Direct Cost Comments 1. Early Autism 4/1/08-3/31/13 RO1 Co-I 4% NIMH $252,927 Risk Longitudinal Investigation (EARLI) Network Autism Centers of Excellence National Institute of Environmental Health Services _ 2. Detection and 4/1/08-3/31/13 RO1 Co-I 0% NIMH $244,000 Care for Depression in the Peripartum _ 3. The National 9/30/05-12/31/10 O-contract PI 35% NIH-NICHD $2,624,000 Children s Study: Montgomery County Vanguard Center _ 4. The National 9/30/07-12/31/12 O-contract PI 20% NIH-NICHD $1,517,205 Children s Study: CHOP Coordinating Center _ 5. Impact of Social 7/1/07-6/30/12 KO1 Advisory Cmte 0% NIH $100,000 Factors on the Effectiveness of a Preconceptional PTB Program _ 20