Online Pharmacology Graduate Programs: An experiment in Progress

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DISCOVERY through integrative research Online Pharmacology Graduate Programs: An experiment in Progress William F. Jackson, Ph.D. jacks783@msu.edu

For more information: hhttp://www.phmtox.msu.edu/education/online/index.html

The Need: Established need for training programs in Integrative Pharmacology 1994 - Jobe, et al. The essential role of integrative biomedical sciences in protecting and contributing to the health and well-being of our nation. The Physiologist 37, 79 86 (1994); reprinted in The Pharmacologist 40, 31 37 (1998). 2004 - NIH, NIGMS RFA Short Course: Integrative and Organ Systems Pharmacology. 2007 - IUPHAR Integrative and Organ Systems Pharmacology Initiative. Fewer opportunities for non-ph.d., post-baccalaureate training in Integrative Pharmacology, particularly for individuals already employed in industry, government and academic labs.

What s a Professional Science Master s Degree?

PSM Programs: http://www.sciencemasters.com/ Are two year, terminal, graduate degree programs. Combine: rigorous study of science or math with skills-based professional course-work in management, policy or law. Most emphasize: writing and communication skills. Generally require: a final project or team experience a real-world experience in a business or public sector enterprise. Are developed in concert with industry, usually through an Advisory Board.

PSM Programs: http://www.sciencemasters.com/ Started in 1997 14 grants from the Alfred P. Sloan foundation programs in the natural sciences and mathematics, and 12 for bioinformatics programs at research institutions. Extended to more institutions in 2001, when the Council of Graduate Studies (CGS) partnered with the Sloan foundation. Received further support in 2006 when the CGS assumed primary responsibility for supporting and expanding the Sloan PSM Initiative. Can be found at more than 130 Universities where there are more than 297 PSM programs.

Goals of MSU s PSM in Integrative Pharmacology: Train individuals in integrative pharmacology and use of animal models for careers in industry, government and academic labs. Design program such that individuals already employed could complete the program while remaining on the job. Generate an alternative revenue stream for Department. Maintain research-intensive focus of the Department

Initial Outline of MSU s PSM in Integrative Pharmacology: Two year program consisting of: On-line courses. Intensive, hands-on, Applied Integrative Pharmacology Lab on campus (Branding experience). On-the-job knowledge application. Final project and report.

Advisory Board: Steven Humphreys - PharmOptima LLC David G. Pegg, Ph.D., D.A.B.T. - formerly with Pfizer Lewis Kinter, Ph.D. - AstraZeneca Pharmaceuticals Bryan F. Cox, Ph.D. - Abbott Laboratories

Working Curriculum Fall 2006 Required courses PHM 819 - Principles of Drug-Tissue interactions PHM 830 - Experimental Design & Data Analysis PHM 832 - Applied Integrative Pharmacology Lab (sevenday on-campus experience) PHM 895 - Applied Project in Integrative Pharmacology Science electives (12 credits or more) PHM 350 - Introduction to Human Pharmacology PHM 450 - Introduction to Toxicology PHM 813 - Cardiovascular Pharmacology PHM 829 - Neuropharmacology PHM 831 - Endocrine Pharmacology PHM 833 - Gastrointestinal & Liver Pharmacology PHM 834 - Respiratory Pharmacology MT 830 - Concepts in Molecular Biology VM 812 - Food Safety Toxicology Professional electives (6 credits or more) PHM 851 - Intellectual Property & Patent Law PHM 854 - Leadership & Team-Building for Researchers PHM 857 - Introduction to Project Management PHM 858 - Project Management & Drug Development MT 842 - Managing Biomedical Laboratory Operations

Working Curriculum - Today Required courses PHM 819 - Principles of Drug-Tissue interactions PHM 830 - Experimental Design & Data Analysis PHM 832 - Applied Integrative Pharmacology Lab (5- day on-campus experience) PHM 895 - Applied Project in Integrative Pharmacology Science electives (12 credits or more) PHM 430 - Human Pharmacology PHM 450 - Introduction to Chemical Toxicology PHM 813 - Cardiovascular Pharmacology PHM 817 Neurotoxicology PHM 822 - Academic & Research Integrity PHM 828 - Concepts in Carcinogenesis PHM 829 - Neuropharmacology PHM 831 - Endocrine Pharmacology PHM 833 - Gastrointestinal & Liver Pharmacology PHM 834 - Respiratory Pharmacology PHM 835 Biopharmaceuticals PHM 837 - Autonomic Pharmacology PHM 840 Safety Pharmacology PHM 841 Cellular and Molecular Toxicology MT 830 - Concepts in Molecular Biology VM 812 - Food Safety Toxicology Professional electives (6 credits or more) PHM 659 Regulatory Affairs and Project Management in Clinical Research PHM 850 Communications for Biomed Res PHM 851 - Intellectual Property & Patent Law PHM 854 - Leadership & Team-Building for Researchers PHM 855 - Business of Biomed Res Orgs PHM 857 - Introduction to Project Management PHM 858 - Drug Development Process MT 842 - Managing Biomedical Laboratory Operations

Startup Challenges: Who would design, implement and teach the on-line courses? How would we fund the program? Marketing. Is there enough demand?

Who designed, implemented and teaches the on-line courses? Design and Teaching: Existing faculty (12 courses) Former students/postdocs (6 courses) Other part-time faculty ( 4 courses) Implementation: Educational Coordinator In-house producer University-supplied producers

How did we fund the program? Seed money from MSU for the first 3 years: Faculty line Educational Coordinator In-house producer Revenue sharing from: large undergraduate on-line pharmacology course new on-line courses NIGMS grant for Integrative Pharmacology Short Course: Provided funds to equip hand-on lab and gain experience with an Integrative Pharmacology lab. Student Fees Pay for supplies for lab course

Marketing: Word of Mouth. Web-presence. Web page Social Media Other Modes not yet used: Cross-listing with other Universities. Trade shows. Direct marketing - visit industries. Direct-mail marketing (expensive!)

Is there enough demand? We think so, based on: Input from Advisory Board and other colleagues in industry. Inquiries about the program. Student demand for offerings of on-line courses. Continuous stream of applications 4-8 per semester We re in the middle of the experiment, Time will tell!

Where are we today: Graduated 29 PSM students, 24 students currently enrolled. Spun off a new MS in Pharmacology and Toxicology in 2009 currently have 148 enrolled and graduated 33. Spun off a Graduate Certificate Program in Safety Pharmacology in late 2012 1 student Financially independent

Advantages of online Programs: Allows students to work full-time and still take classes. Student centered education promotes independent learning. Modular nature provides flexibility and ability to change courses to meet student demands, and for multi-use.

Challenges of Online Programs: Obtaining/maintaining faculty buy-in. Startup costs time and actual $$$. Designing interactivity into courses. Understanding what students don t understand. Incorporating interactivity. Managing part-time faculty. Maintaining the revenue stream in the face of University financial pressures. Assessment.

The future: Hybrid Courses The best of both worlds! Excellent use of faculty and student time. Biggest danger is trying to include too much in the online segment and to not integrate the online material with faceto-face.

For more information: http://www.phmtox.msu.edu/education/online/index.html

Characteristics of PSM programs: Two year interdisciplinary programs Close association with Industry > 50% of course work in Sciences. Inclusion of Professional Courses: Business fundamentals, Finance and Marketing, Project Management, Communications, Team building, etc. Internships or other hands-on experience Final applied project