3 rd Edition Preliminary Programme Call deadline December 9, 2014 for Abstract orkshop Scientific Coordinators Antonella d Arminio Monforte (Milan, I) Carlo Federico Perno (Rome, I) Massimo Puoti (Milan, I) Milan, Italy Palazzo delle Stelline January 26-27, 2015
orkshop Scientific Coordinators Antonella d Arminio Monforte San Paolo Hospital, Carlo Federico Perno University of Tor Vergata, Rome I Massimo Puoti Niguarda Ca Granda Hospital, Milan I Honorary President Mauro Moroni Professor Emeritus, Scientific Secretariat Francesca Ceccherini-Silberstein University of Tor Vergata, Rome I Giulia Marchetti San Paolo Hospital, Roberto Rossotti Niguarda Ca Granda Hospital, Milan I Milan, Italy January 26-27, 2015
Faculty Alessio Michele Aghemo Foundation IRCCS Maggiore Hospital, Massimo Andreoni University of Tor Vergata, Rome I Gioacchino Angarano University Hospital of Bari I Mario Angelico University of Tor Vergata, Rome I Andrea Antinori IRCCS - INMI Lazzaro Spallanzani, Rome I Stefano Bonora University of Turin I Raffaele Bruno University of Pavia I Savino Bruno Fatebenefratelli Hospital, University Milan Bicocca, Milan I Giampiero Carosi Professor Emeritus, University of Brescia I Antonella Castagna San Raffaele Scientific Institute, Milan I Dario Cattaneo San Paolo Hospital, Francesca Ceccherini-Silberstein University of Tor Vergata, Rome I Massimo Colombo Foundation IRCCS Maggiore Hospital, Andrea Cossarizza University Hospital of Modena and Reggio Emilia, Modena I Antonella d Arminio Monforte San Paolo Hospital, Gabriella d Ettorre University Hospital Umberto I, Rome I Andrea De Luca Siena University Hospital, Siena I Andrea De Maria University of Genoa, IRCCS AOU San Martino - IST Genoa I Giovanni Di Perri University of Turin I Daniel C. Douek Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda USA Carlo Ferrari University Hospital of Parma I Courtney V. Fletcher University of Nebraska Medical Center, College of Pharmacy, Omaha USA Charles W. Flexner Johns Hopkins University, Baltimore USA Giovanni Battista Gaeta Second University of Naples I Massimo Galli Luigi Sacco Hospital, Alessia Maria Giorgini San Paolo Hospital, Enrico Girardi IRCCS - INMI Lazzaro Spallanzani, Rome I Andrea Gori San Gerardo Hospital, Monza I Peter Hunt University of California, San Francisco USA Giuseppe Ippolito IRCCS - INMI Lazzaro Spallanzani, Rome I Paul Klenerman Nuffield Department of Medicine, University of Oxford UK Adriano Lazzarin University Vita-Salute San Raffaele, Milan I Michael M. Lederman Case Western Reserve University School of Medicine, University Hospitals/ Case Medical Center, Cleveland USA Massimo Levrero Sapienza University, Rome I Miriam Lichtner Sapienza University of Rome, Polo Pontino, Latina I Giulia Marchetti San Paolo Hospital, Fabio Marra University of Florence I Claudio Maria Mastroianni Sapienza University of Rome, Polo Pontino, Latina I Gabriele Missale University Hospital of Parma I Mauro Moroni Professor Emeritus, Carlo Federico Perno University of Tor Vergata, Rome I Massimo Pinzani Institute for Liver and Digestive Health, University College London, Royal Free Hospital, London UK Teresa Maria Pollicino G. Martino University Hospital, Messina I Massimo Puoti Niguarda Ca Granda Hospital, Milan I Giovanni Raimondo University Hospital of Messina I Giuliano Rizzardini Luigi Sacco Hospital, Teresa Antonia Santantonio University Hospital of Foggia I Annalisa Saracino University Hospital of Bari I Guido Silvestri Emory University School of Medicine, Yerkes National Primate Research Center, Atlanta USA Mario Strazzabosco University Milan Bicocca, Milan I Valentina Svicher University of Tor Vergata, Rome I Gloria Taliani Sapienza University, Rome I Camilla Tincati San Paolo Hospital, Erica Villa University of Modena and Reggio Emilia, Modena I Massimo Zuin San Paolo Hospital,
orkshop January 26, 2015 11.00-11.10 Welcome addresses A. d Arminio Monforte, C.F. Perno, M. Puoti 11.10-11.40 OPENING LECTURE 11.10-11.30 Innovation in medicine: where we are going? G. Ippolito 11.30-11.40 Discussion 11.40-12.10 LECTURE Conveners: M.M. Lederman, M. Moroni 11.40-11.50 Framing the problem M.M. Lederman 11.50-12.10 HIV pathogenesis G. Silvestri 12.10-13.50 SESSION 1 Mechanisms of viral persistence: what role for the virus and what for the host? Conveners: G. Di Perri, M. Strazzabosco 12.10-12.20 Framing the problem C.F. Perno 12.20-12.50 HIV What obstacles for the cure? The host vs the virus D.C. Douek 12.50-13.10 HCV Why the virus becomes chronic? P. Klenerman 13.10-13.30 HBV Why the virus becomes chronic? T.M. Pollicino 13.30-13.50 Discussion A.M. Aghemo, A. Cossarizza 13.50-14.30 Lunch 14.30-15.30 SESSION 2 Oral communications based on selected abstracts Conveners: S. Bruno, C.M. Mastroianni
Preliminary Programme January 26, 2015 15.30-17.20 SESSION 3 Beyond viral undetectability in plasma: which markers of therapy outcome Conveners: M. Colombo, G. Rizzardini 15.30-16.00 HIV Case presentation and open questions 15.30-15.50 HIV case presentation G. d Ettorre 15.50-16.00 Open questions P. Hunt 16.00-16.30 HCV Case presentation and open questions 16.00-16.20 HCV case presentation F. Ceccherini-Silberstein 16.20-16.30 Open questions M. Zuin 16.30-17.00 HBV Case presentation and open questions 16.30-16.50 HBV case presentation V. Svicher 16.50-17.00 Open questions G. Raimondo 17.00-17.20 Discussion A. Gori 17.20-19.10 SESSION 4 Eradication and functional cure: pharmacology Conveners: A. Antinori, G. Carosi 17.20-17.30 Framing the problem A. Antinori 17.30-17.50 Insight the HIV reservoirs C.V. Fletcher 17.50-18.10 Insight the HCV-related cirrhosis F. Marra 18.10-18.30 Long-Acting injectable ARVs: dream or reality? C.W. Flexner 18.30-18.50 Insight the HBV reservoirs M. Levrero 18.50-19.10 Discussion D. Cattaneo Milan, Italy January 26-27, 2015
orkshop January 27, 2015 08.30-09.00 LECTURE Conveners: G.B. Gaeta, A. Lazzarin 08.30-08.50 Impact of HIV & HCV viral burden at population level: what strategies to contain epidemics? E. Girardi 08.50-09.00 Discussion 09.00-09.30 LECTURE Conveners: G. Angarano, M. Galli 09.00-09.20 CCR5 and modulation of fibrosis progression in HIV/HCV coinfection R. Bruno 09.20-09.30 Discussion 09.30-11.00 SESSION 5 Difficult to treat patients: what therapeutic strategy? Conveners: M. Andreoni, G. Missale 09.30-09.40 Framing the problem M. Andreoni 09.40-10.10 High HIV viremia: case presentation and open questions 09.40-10.00 Does more aggressive anti HIV therapy work? C. Tincati 10.00-10.10 Open questions A. De Luca 10.10-10.40 HCV-related cirrhosis: case presentation and open questions 10.10-10.30 What treatment options for low HCV decay? A.M. Giorgini 10.30-10.40 Open questions M. Pinzani 10.40-11.00 Discussion M. Angelico
Preliminary Programme January 27, 2015 11.00-12.00 SESSION 6 Oral communications based on selected abstracts Conveners: A. De Maria, C. Ferrari, A. Saracino 12.00-13.50 SESSION 7 Infection and gender: any differences? Convener: T.A. Santantonio 12.00-12.10 Framing the problem A. d Arminio Monforte 12.10-12.30 Antiviral drug toxicity and pharmacokinetics S. Bonora 12.30-12.50 HIV: which biological differences according to gender? G. Marchetti 12.50-13.10 HCV: natural history of chronic liver disease E. Villa 13.10-13.30 The setting of HIV/HCV coinfection G. Taliani 13.30-13.50 Discussion A. Castagna, M. Lichtner 13.50-14.00 SESSION 8 Awards ceremony and closing remarks A. d Arminio Monforte, C.F. Perno, M. Puoti Milan, Italy January 26-27, 2015
orkshop Milan, Italy January 26-27, 2015 Workshop Venue Palazzo delle Stelline Corso Magenta, 61 20123 Milan, Italy www.stelline.it Abstract submission Abstract submission instructions and electronic abstract form available online at www.innovation2015.it Submission by e-mail not accepted Deadline December 9, 2014 Abstract submission deadline CME Provider and Organizing Secretariat Effetti srl Via Gallarate, 106-20151 Milan, Italy Phone +39 02 3343281 Fax +39 02 38002105 Mail: innovation2015@effetti.it www.innovation2015.it