UNIVERSITY OF MIAMI COLLEGE OF ENGINEERING

The Department of Biomedical Engineering UNIVERSITY OF MIAMI COLLEGE OF ENGINEERING

CHAIRMAN S MESSAGE On behalf of the Biomedical Engineering faculty and staff, thank you for your interest in discovering the educational opportunities available in our department. Biomedical Engineering is a dynamic discipline in great demand thanks to significant strides in research, medicine, and technology. The field of biomedical engineering provides a wide spectrum of opportunities for work and study. Since its inception in 1967, our department has grown to a vibrant and diverse academic community, with a renowned research program. With a low student to faculty ratio and a focus on providing every student with the opportunity to conduct hands-on research, our Accreditation Board of Engineering and Technology (ABET) accredited program provides an unparalleled educational experience. Housed within the University of Miami, a top 50 ranked institution by the US News & World Report since 2008 and the highest ranked school in the State of Florida, we provide a diverse and dynamic environment for research and education. Our strong collaborations with Institutes and Centers within the Miller School of Medicine, a top ranked medical school, illustrate the strong interdisciplinary and translational focus of our faculty and students within the field of biomedical engineering. Our faculty has procured research funding from a diverse range of sources, including the National Institutes of Health, the National Science Foundation, the Department of Defense, Defense Advanced Research Projects Agency; foundations, such as American Federation for Aging Research, the Diabetes Research Institute Foundation; and industrial partners, such as Alcon, Carl- Zeiss Meditech, Lockheed Martin Aculight, Intelligent Hearing Systems, Advanced Brain Monitoring and Medtronic. We have leveraged this enriching environment to grow in strength both in new faculty recruitment and student enrollment. Within the last five years, six new faculty were recruited and student enrollment increased 23% and 38% for undergraduates and graduates, respectively. I anticipate we will continue this trend of unprecedented growth and evolution. It has been a privilege and an honor to guide this dynamic department for more than a decade and I look forward to the further contributions our graduating scholars will make in the near future. UM BME Snapshot Faculty - 15 Primary - 30 Secondary Student Enrollment - 250 Undergraduates - 80 Graduate Undergraduate Concentrations - Electrical - Mechanical - Biomaterials and Tissue - Premedical Sincerely, Ozcan Ozdamar, Ph.D. Professor and Chair Cover Page Clockwise from top left: Direct neural control of a Touch Bionics ilimb dexterous prosthetic hand; Periodontal ligament-derived stem cells loaded with super-paramagnetic iron oxide particles (red) and stained for filamentous actin (F-actin) cytoskeleton (green); fabrication of PDMS macro-porous scaffolds; Auditory evoked potential cartography mapped on a 3-D human head; Demonstration of laser beam delivery using mirrors and beam splitters.

WHY THE? Located in beautiful and historic Coral Gables, a suburb of Miami, the University of Miami is an ideal location for students to both learn and engage in the challenges of their new student lives. The University of Miami, like the city of Miami, represents a mosaic of cultures and dynamic ideas from around the world. Miami offers some of the most exciting cultural events in the country including the Miami Book Fair, Art Basil, and many events at the Adrienne Arsht Center. The University of Miami offers a world of activities for the students to participate both on our beautiful University of Miami campus, as well as popular spots like South Beach, the Florida Keys, and Everglades National Park. Students have plenty of opportunities for watersports, hiking, and riding bicycles. Downtown Miami, also near to the school, is a thriving sports and cultural center. On campus, more than 1,500 students are involved in approximately 30 fraternities and sororities. Students can also choose from more than 270 clubs and organizations to join. Residential colleges, modeled after housing at England s Oxford and Cambridge universities, combine living and learning with group meals, poetry readings, sports, and more. University of Miami Division I Hurricanes compete in the Coastal Division of the Atlantic Coast Conference. Annual campus events include the Canes Film Festival, which showcases student-produced movies, and Sportsfest, three days of competition between residence hall teams. Undergraduates are also known for upholding school spirit with traditions like the Boat Burning Ceremony held on Lake Osceola, Homecoming, and Freshman Walk, in which first-year students circle the football field during a home game. The University of Miami classes are structured with an emphasis on the individual, enabling the student to build personal relationships with his or her professors and mentors. The University s Toppel Career Center matches students and alumni with job prospects through career expos, individual advising, and on-line resources. The Launch Pad also helps aspiring entrepreneurs develop their ideas with coaching events, workshops and a broad network of experienced entrepreneurs. Fast Facts about the U Founded in 1925 Total undergraduate enrollment: 10,509 Campus size of 239 acres 9 undergraduate schools and colleges Faculty to student ratio of 1:11 Ranked #44 Best Colleges and National Universities * Highest ranked school in the state of Florida Ranked 60th of all universities in expenditures of federal funds for R&D *2012

UNDERGRADUATE PROGRAM The Department of Biomedical Engineering at the University of Miami offers an undergraduate program leading to the Bachelor of Science (B.S.) degree. The undergraduate BME program was the first of its kind in Florida and is accredited by the Accreditation Board for Engineering and Technology (ABET). Some special features of the program include the small class size and open-door policy of the faculty, which facilitates studentfaculty interaction. The Department has very strong ties with the University of Miami Miller School of Medicine. Undergraduate students have a wide range of research and internship opportunities in some of the leading research laboratories in their respective fields. The Department strongly encourages undergraduate student participation in research and professional activities. UNDERGRADUATE CURRICULUM The three educational objectives of the Biomedical Engineering program are achieved via the implementation of a curriculum with four parallel concentrations which include a common core and concentration-specific courses. The core curriculum is designed to provide a broad foundation in the basic sciences and in engineering. The four concentrations are Electrical (E), Mechanical (M), Biomaterials and Tissue (B), and Premedical (P). The Premed concentration satisfies the requirements for admission to medical school and provides depth in the area of biomaterials and tissue engineering. The curriculum is designed to provide all graduates with the analytical and design skills required to formulate and solve problems at the interface of engineering and life sciences. Outstanding students are well prepared for graduate studies or medical school DESIGN AND RESEARCH EXPERIENCE The biomedical engineering design experience is integrated in the curriculum throughout the four years of study, starting in the freshman year. Each semester includes classroom or laboratory courses which place a heavy emphasis on theoretical and practical biomedical engineering design concepts. The design experience culminates in the senior year with a year-long capstone Senior Design Project. The Senior Design Project is typically completed by teams of two students who build on their knowledge and previous design experience to solve one major design problem which integrates the various components of the curriculum. The senior project starts in the second semester of the junior year with a 1-credit course which covers the basic principles of biomedical engineering design. The curriculum includes a Technical Entrepreneurship course which can serve as an alternative to the Senior Design Project. The students form entrepreneurial teams of 4 to 6 members to design and develop new products, including a business or commercialization plan. This course was established with a grant from the National Collegiate Innovators and Inventors Alliance (NCIIA) in 1999 and is currently supported by additional grants from NCIIA. B.S. / M.S. COMBINED PROGRAM For highly motiviated undergraduates, a five-year Bachelor of Science and Master of Science BS/MS degree program is offered. This program is specifically designed for those students who want to pursue their graduate study as they are completing their undergraduate study. College of Engineering Undergraduate Student Snapshot* The mean SAT score of entering freshman class was 1327, up from 1315 just last Fall Underrepresented minorities for the total student population is currently 26% Hispanic, 10% Asian/Pacific Islander, and 6% African American 30% of our freshman students are women, significantly higher than the national average of 19% Over the past five years, the College of Engineering has experienced a 77% increase in undergraduate freshman applications, according to numbers released by the Office of Undergraduate Admissions *Fall 2011

GRADUATE PROGRAM The Department of Biomedical Engineering offers programs leading to the Master of Science (thesis or non-thesis option) and Doctor of Philosophy degrees. Under the guidance of an academic advisor from the Department, each student designs an individual program of study and research. MASTERS OF SCIENCE The Master of Science degree offers the graduate student an opportunity to obtain advanced training in selected areas of biomedical engineering and to begin independent research. The department admits four types of students to its MS program: a) Students with BS degrees in Biomedical Engineering or similar engineering fields; b) Students with BS degrees in Electrical, Computer, Mechanical, Chemical, or similar engineering fields; c) Students with BS degrees in Physics, Mathematics, Computer Science, Chemistry, Biology or similar fields; d) Students with MD or similar degrees. Both a 30-credit thesis option and a 30 credit non-thesis option are available. Qualified students enrolled in the undergraduate program can receive their MS degree in a unique combined (BS/MS) program as outlined in the Undergraduate section. DOCTOR OF PHILOSOPHY The program is designed to train students for advanced independent research and technical innovation in biomedical engineering. In general, the department admits three types of students to its PhD program: a) Students with MS degrees in Biomedical Engineering or related science and engineering fields; b) Students with MD degrees with undergraduate degrees in sciences or engineering; c) Highly qualified students with BS degrees in engineering or sciences (direct BS to PhD track). SCHOLARSHIPS AND FINANCIAL ASSISTANCE Financial support in the form of teaching and research assistantships (TAs, RAs) is available to outstanding doctoral students, depending on the availability of funds, the research needs of the Faculty and the teaching needs of the Department. Assistantships typically provide support (stipend, tuition waiver, and insurance subsidy) for up to 4 years and are 12 month appointments. Our website lists the current stipend and insurance support levels. BME Graduate Student Snapshot* The total number of current M.S. and Ph.D. students is 38 and 42, respectively The average G.P.A. and G.R.E. of incoming Ph.D. students was 3.63 and 1352, respectively Our graduate students represent a diverse and dynamic population, with 45 % women and 43 % international Ph.D. students Over 20% of our students are funded by their own individual competitive extramural fellowship awards, from agencies such as the National Institutes of Health and the Gates Foundation A strong majority, over 70%, of our graduates take positions in Academia One of our first Ph.D. graduates was recently inducted into the National Academy of Engineering *Fall 2012

RESEARCH AREAS The application of electromagnetic, acoustic, thermal, and other forms of energy plays a significant role in biomedical research, diagnostics and therapeutics. Novel approaches for non-invasive and minimally-invasive detection and treatment of diseases and characterization of anatomical structure and physiological function of tissues and organs are made possible by recent advances in imaging, optical, and laser technology. Research at our department focuses on the development of image-guided treatment modalities, including robotic surgery; the development of imaging modalities and processing algorithms for MRI, nuclear imaging, optical coherence tomography and atomic force microscopy; the development of laser and thermal energy delivery systems and optical stimulation; the characterization of tissue structure and physiological function of ear, eye and brain tissues. Active research is conducted in close collaborations with Neurology, Neurosurgery, Ophthalmology, Otolaryngology, Radiology, Radiation Oncology, and Urology. NEURAL ENGINEERING, BIOMEDICAL SIGNALS, AND INSTRUMENTATION The development of novel instrumentation and signal processing strategies to probe neural function has significantly improved our knowledge of the nervous system. With neural disorders afflicting millions of Americans and resulting in significant healthcare costs, new diagnostic and treatment modalities for these disorders can provide substantial benefits, with broad applicability to all medical conditions. Research at our department includes the development of vision, hearing and balance assessments, neural interfaces, neuroprosthetic devices, and new stimulation paradigms such as high rate and pulsed infrared neural stimulation. Researchers are utilizing neural imaging, brain-computer interfaces, and computational approaches to explain neural function and disorders. Instruments using computers and photonics are being developed for intraoperative monitoring, clinical evaluations and therapeutic interventions. Research is in close collaboration with Anesthesiology, Miami Project to Cure Paralysis, Neuroscience, Neurology, Otolaryngology, Ophthalmology, Radiology, Urology, and industry partners.

BIOMECHANICS, BIOMATERIALS AND TISSUE ENGINEERING The focus of this field of research is to harness the potential of the dynamic, living cell in order to understand cellular/tissues processes, predict cellular/tissue behavior, and engineer functional human tissues. Through the integrated use of cells, biomaterial scaffolds, and bioreactors, we can engineer tissue grafts for regenerative medicine, develop enabling technologies for stem cell research, design high-fidelity models for studies of tissue development, remodeling and disease, and guide the host response to support the transplant. In our department, researchers are harnessing the power of the cells and tissues to: characterize native tissue biomechanics and cell mechanobiology and predict pathological states; incorporate biomechanical signals to direct stem cell differentiation; develop novel, bioactive materials to instruct host responses, such as angiogenesis and immunoregulation; and engineer functional tissue implants to treat cardiovascular, orthopedic, ophthalmologic, and endocrinology diseases. Research is conducted in collaboration with Cardiology, Surgery, Orthopaedics, Ophthalmology, Medicine, the Diabetes Research Institute, the Stem Cell Institute, the VA Medical Center, and industrial partners. AFFILIATED CENTERS AND INSTITUTES at MEDICAL CAMPUS BASCOM PALMER EYE INSTITUTE DIABETES RESEARCH INSTITUTE EAR INSTITUTE INTERDISCIPLINARY STEM CELL INSTITUTE MIAMI PROJECT TO CURE PARALYSIS MIAMI TRANSPLANT INSTITUTE MIAMI VETERAN AFFAIRS MEDICAL CENTER

Ozcan Ozdamar Professor & Chairman oozdamar@miami.edu Secondary Appointment in Pediatrics and Otolaryngology Ph.D. in Biomedical Engineering, Northwestern University, 1976 Neurosensory instrumentation and engineering, neurophysiological signal processing, auditory / visual evoked responses, electrophysiological brain monitoring, electrocochleography and electroretinography Fotios Andreopoulos Associate Professor fandreopoulos@miami.edu Secondary Appointment in Surgery & Vascular Biology Institute Ph.D. in Chemical Engineering, University of Pittsburgh, 1999 Biomaterial development, drug delivery systems, therapeutic angiogenesis, tissue engineering scaffolds, cutaneous regeneration Jorge Bohorquez Assistant Professor of Professional Practice jbohorquez@miami.edu Ph.D. in Biomedical Engineering, INSA Institut National des Sciences Appliquées de Lyon, France, 1991 Engineering education, microcomputer-based bioinstrumentation, objective hearing assessment, monitoring retinal function Herman Cheung James L. Knight Professor hcheung@med.miami.edu Secondary Appointment in Medicine and Senior VA Medical Research Career Scientist Ph.D. in Molecular Biology, University of Southern California, 1974 Stem cell-based tissue engineering on cardiovascular, bone, cartilage and ocular tissues; mechanobiology; and smoking effects on stem cells

Edward A. Dauer Research Associate Professor edauer@miami.edu Secondary Appointment in Radiology and Family Medicine M.D. (1975) and MS (2001) in Biomedical Engineering, University of Miami Scanning Electron Microscopy, medical physics, and radiation biology C-Y Charles Huang Assistant Professor c.huang@miami.edu Ph.D. in Mechanical Engineering, Columbia University, 2001 Mechanobiology, mesenchymal stem cells, biomechanics, cartilage tissue engineering, and bioreactor development Alicia Jackson Assistant Professor a.jackson2@miami.edu Ph.D. in Biomedical Engineering, University of Miami, 2010 Transport and nutritional supply to cells/tissues, biomechanics of soft tissues, mechanobiology, finite element analysis, orthopaedic tissues Fabrice Manns Associate Professor & Graduate Program Director Secondary Appointment in Ophthalmology fmanns@miami.edu Ph.D. in Biomedical Engineering, University of Miami, 1996 Laser applications in medicine, ophthalmic imaging, optics of the eye and vision correction, and ophthalmic technologies

Leonard Pinchuk Distinguished Research Professor in Biomedical Engineering President and CEO Innovia LLC and its Affiliated Companies Member, National Academy of Engineering Ph.D. in Biomedical Engineering, University of Miami, 1984 D.Sc. (h.c) McGill University, 2005 Biomaterials, ophthalmic and cardiovascular implantable medical devices Suhrud M. Rajguru Assistant Professor Secondary Appointment in Otolaryngology s.rajguru@miami.edu Ph.D. in Bioengineering, University of Utah, 2006 Optical stimulation of excitable cells, infrared neural stimulation, neuroprosthetics, neural engineering, neurophysiology and biomechanics. Nelson Salas Research Assistant Professor nsalas@med.miami.edu Ph.D. in Biomedical Engineering, University of Miami, 2007 Energy-ablative treatments, laparoscopy instrumentation, laser-tissue interactions, biomedical optics, endoscopy and non-invasive imaging Justin Sanchez Associate Professor jcsanchez@miami.edu Secondary Appointment in Neuroscience & Miami Project to Cure Paralysis Ph.D. in Biomedical Engineering, University of Florida, 2004 Neuroprosthetics, brain-machine interfaces, brain-computer interfaces, neural engineering, neural coding, deep brain stimulation, motor system, and limbic system

Cherie Stabler Associate Professor cstabler@miami.edu Secondary Appointment in Surgery & Diabetes Research Institute Ph.D. in Biomedical Engineering, Georgia Institute of Technology & Emory University, 2004 Tissue engineering, bioartificial pancreas, bioactive biomaterials, controlled release biomaterials, immuno-modulatory materials Weizhao Zhao Associate Professor w.zhao1@miami.edu Secondary Appointment in Radiology and Neurology Ph.D. in Electrical & Computer Engineering, University of Miami, 1991 Medical image processing, radioisotope labeled imaging, medical imaging simulation, image-guided intervention Noel Ziebarth Assistant Professor nziebarth@miami.edu Ph.D. in Biomedical Engineering, University of Miami, 2008 Ocular biomechanics, cellular biomechanics, imaging, atomic force microscopy Secondary Faculty Noam Alperin, Radiology Shihab Asfour, Industrial Engineering Horst J. Baier, Medicine Norman L. Block, Urology Joseph A. Both, Radiation Oncology Adrien Eshragi, Otolaryngology Michalis Georgiou, Nuclear Medicine Weiyong Gu, Mechanical Engineering Joshua M. Hare, Cardiology Xiang Run Huang, Ophthalmology Barry E. Hurwitz, Psychology Lee Kaplan, Orthopedics Norma Sue Kenyon, Surgery Raymond J. Leveillee, Urology Na Li, Mechanical Engineering Philip M. McCabe, Psychology Richard McNeer, Anesthesiology Jean-Marie A. Parel, Ophthalmology Pradip Pattany, Radiology Brant D. Watson, Neurology Si Pham, Surgery Sonia H. Yoo, Ophthalmology Antonello Pileggi, Surgery Vittorio Porciatti, Ophthalmology Kenneth G. Proctor, Anesthesiology Camillo Ricordi, Surgery Neil Schneiderman, Psychology Fred Telischi, Otolaryngology Adam Wanner, Medicine

COLLEGE OF ENGINEERING MIAMI Mailing Address: P.O. Box 248294 Coral Gables, FL 33124-0621 Phone: (305)284-2445 Fax: (305)284-6494 Physical Address: 1251 Memorial Drive McArthur Engineering Annex (MEA) #219A Coral Gables, FL 33146 www.bme.miami.edu