Fall 2015 PHS 616 Online University of Waterloo. Week Module Activities and Assignments End / Due Date Weight (%) Assignment 2 (due)



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Course Schedule Important: ALL TIMES EASTERN - Please see the University Policies section of your Syllabus for details. Week Module Activities and Assignments End / Due Date Weight (%) Week 1 Module 1: Decision Introduce Yourself Ungraded Week 2 Making in Healthcare Assignment 1 (begin) Week 3 Module 2: Probability Theory Assignment 1 (due) Friday, October 2, 2015, at 12:05 PM 10% Assignment 2 (begin) Week 4 Week 5 Module 3: Statistical Inference and Decision Theory Assignment 2 (due) Assignment 3 (begin) Friday, October 16, 2015, at 12:05 PM 15% Week 6 Week 7 Week 8 Module 4: Machine Learning Assignment 3 (due) Friday, November 6, 2015, at 12:05 PM 25% Assignment 4 (begin) Week 9 Week 10 Module 5: Practical Decision Making in Health Informatics Assignment 4 (due) Friday, November 20, 2015, at 12:05 PM Discussions: Module 5, Week 10: Obesity Paradox Friday, November 20, 2015, at 12:05 PM 15% 5% Assignment 5 (begin) Week 11 Discussions: Module 5, Week 11: End-of-Life Decision Making in Intensive Care Units Friday, November 27, 2015, at 12:05 PM 5% Week 12 Discussions: Module 5, Week 12: Effective Cooperation Between Humans and Machines in Health Decision Making Friday, December 4, 2015, at 12:05 PM 5%

Week 13 Assignment 5 (due) Friday, December 11, 2015, at 12:05 PM Discussions: Questions and Answers about R (throughout the term) 20% 1-3% (Bonus) Offcial Grades and Course Access Official Grades and Academic Standings are available through Quest. Your access to this course will continue for the duration of the current term. You will not have access to this course once the next term begins.

Contact Information News Your instructor uses the News widget of the Course Home page to make announcements during the term to communicate new or changing information regarding due dates, instructor absence, etc., as needed to communicate with students. You are expected to read the News on a regular basis. To ensure you are viewing the complete list of news items, you may need to click Show All News Items. Discussions A General Discussion topic* has also been made available to allow students to communicate with peers in the course. Your instructor may drop in at this discussion topic. Help with R Software If you have any questions or comments regarding R software, please post them in the Questions and Answers about R discussion forum. Your instructor will monitor this forum. Contact Us Who and Why Instructor Course-related questions (e.g., course content, deadlines, assignments, etc.) Questions of a personal nature Contact Details Post your course-related questions to the Ask the Instructor discussion topic*. This allows other students to benefit from your question as well. Questions of a personal nature can be directed to your instructor or your TA. Instructor: Joon Lee joon.lee@uwaterloo.ca +1 519-888-4567 ext. 31567 Office hours: by appointment only (send an email to book an appointment) Your instructor checks email and the Ask the Instructor discussion topic* frequently and will make every effort to reply to your questions within 24 48 hours, Monday to Friday. Technical Support, Centre for Extended Learning Technical problems with Waterloo LEARN learnhelp@uwaterloo.ca Include your full name, WatIAM user ID, student number, and course name and number. Learner Support Services, Useful Information for Students in Online Courses

Centre for Extended Learning General inquiries WatCards (Student ID Cards) Examination information extendedlearning@uwaterloo.ca +1 519-888-4002 Include your full name, WatIAM user ID, student number, and course name and number. *For information on discussion topics graded for participation, go to Discussions: Module 5 Weekly Topics. Discussion topics can be accessed by clicking Connect and then Discussions on the course navigation bar above.

Course Description and Objectives Description This course focuses on the process by which decisions are made and how decision-making processes can be codified and machine supported. It will include topics such as reasoning and inference, techniques for managing uncertainty and information representation. The course is anchored in a systems thinking approach to problem solving. Course-level Learning Objectives Describe the current limitations of evidence-based decision making in health. Analyze how decision making in health can be supported by knowledge extracted from data. Apply probability theory, statistical inference, machine learning, and decision theory to optimal decision making under uncertainty. Adapt R programming to decision making applications in health. Acquire data manipulation and representation skills in R. Outline the pragmatic challenges with making optimal decisions in health. Propose how humans and computers can complement each other toward making optimal decisions in health. This online course was developed by Joon Lee, with instructional design and multimedia development support provided by the Centre for Extended Learning. Further media production was provided by Instructional Technologies and Multimedia Services.

About the Course Author Course Author Joon Lee Educational Background Joon Lee received a BASc degree in electrical engineering from the Department of Electrical and Computer Engineering at the University of Waterloo. He received a PhD degree in biomedical engineering from the Department of Electrical and Computer Engineering at the University of Toronto. He completed a 3 year postdoctoral fellowship in medical informatics at the Harvard-MIT Division of Health Sciences and Technology. Currently, he is an Assistant Professor at the School of Public Health and Health Systems at the University of Waterloo. Current Research Joon s research areas include public health informatics, medical informatics, and health data analytics. His research agenda is highly applied, with a strong interest in betterment of various healthcare and public health systems via innovative informatics technologies. Hobbies/Interests/Sports Joon is a general sports fan and roots for all Toronto teams and the New England Patriots. He also enjoys reading non-fiction books, watching movies, and socializing over a beer or two.

Materials and Resources Required Textbook and Documentation Textbooks (Free and available online) 1. MacKay, D. J. (2003). Information theory, inference, and learning algorithms. Cambridge, UK: Cambridge University Press. [PDF] 2. Grinstead, C. M., and Snell, J. L. (1997). Introduction to probability (2nd rev. ed.). Providence, RI: American Mathematical Society. [PDF] R documentation (Free and available online) 3. Owen, W. J. (2010). The R Guide, Version 2.5. University of Richmond, VA, U.S. [PDF] 4. Venables, W. N. and Smith D. M. and the R Core Team. (2013). An Introduction to R. [PDF] Required Software R. (a free software environment for statistical computing and graphics) by the R Foundation for Statistical Computing, Institute for Statistics and Mathematics, Vienna Austria. R Studio. NOTE: Instructions for download and installation are given on the Module 1: Week 1 page. Required Datasets The datasets in the list below were taken from StatLib---Disease Data, 1991 Exposition, and provided by "Statistics in Public Health Surveillance," an exposition/poster session held at the August 1991 Joint Statistical Meetings in Atlanta, sponsored by the American Statistical Association (ASA) Section on Statistical Graphics. Datasets "mumps_ms" and "tb" were provided by the Centers for Disease Control; datasets "census_80" and "fips_80" were from the U. S. Bureau of the Census. For a description of these datasets, please see the National Notifiable Diseases Data. census_80.csv fips_80.csv mumps_ms.csv tb.csv Resources R Reference Card (PDF) Provides examples of R commands.

University of Waterloo Library (Services for Students Taking Online Courses)

Grade Breakdown Description The following represents the Grade Breakdown of this course. Activities and Assignments Weight (%) Assignments Assignment 1 10% Assignment 2 15% Assignment 3 25% Assignment 4 15% Assignment 5 20% Discussions Discussions: Module 5, Week 10 5% Discussions: Module 5, Week 11 5% Discussions: Module 5, Week 12 5% Discussions: Questions and Answers about R 1-3% (Bonus)

Course and Department Policies School of Public Health and Health Systems Course Assignments and Examinations For detailed information regarding late assignments, missed tests/examinations, and other department policies applicable to this course, please refer to the Practice Regarding Course Assignments and Examinations (PDF) document. For the assignment questions that involve R programming, you are allowed to work with your classmates but you must ensure that your submission is your own work. All submitted R scripts will be explicitly checked for possible unauthorized collaboration. Any alleged academic offence will be investigated in a serious manner. Please refer to the academic integrity code described in the University Policies section. Reassessment of Grades For information about reassessment of grades, please see the Faculty of Applied Health Sciences Grade Reassessment Policy. (PDF)

University Policies Submission Times Please be aware that the University of Waterloo is located in the Eastern Time Zone (GMT or UTC-5 during standard time and UTC-4 during daylight saving time) and, as such, the time that your activities and/or assignments are due is based on this zone. If you are outside the Eastern Time Zone and require assistance with converting your time, please try the Ontario, Canada Time Converter. Accommodation Due to Illness If your instructor has provided specific procedures for you to follow if you miss assignment due dates, term tests, or a final examination, adhere to those instructions. Otherwise: Missed Assignments/Tests/Quizzes Contact the instructor as soon as you realize there will be a problem, and preferably within 48 hours, but no more than 72 hours, have a medical practitioner complete a Verification of Illness Form. Email a scanned copy of the Verification of Illness Form to your instructor. In your email to the instructor, provide your name, student ID number, and exactly what course activity you missed. Further information regarding Management of Requests for Accommodation Due to Illness can be found on the Accommodation due to illness page. Missed Final Examinations If you are unable to write a final examination due to illness, seek medical treatment and have a medical practitioner complete a Verification of Illness Form. Email a scanned copy to the Centre for Extended Learning (CEL) at extendedlearning@uwaterloo.ca within 48 hours of your missed exam. Make sure you include your name, student ID number, and the exam(s) missed. You will be REQUIRED to hand in the original completed form before you write the make-up examination. After your completed Verification of Illness Form has been received and processed, you will be emailed your alternate exam date and time. This can take up to 2 business days. If you are within 150 km of Waterloo you should be prepared to write in Waterloo on the additional CEL exam dates. If you live outside the 150 km radius, CEL will work with you to make suitable arrangements. Further information about Examination Accommodation Due to Illness regulations is available in the Undergraduate Calendar. Academic Integrity In order to maintain a culture of academic integrity, members of the University of Waterloo community are expected to promote honesty, trust, fairness, respect, and responsibility. If you have not already completed the online tutorial regarding academic integrity you should do so as soon as possible. Undergraduate students should see the Academic Integrity Tutorial and graduate students should see the Graduate Students and Academic

Integrity website. Proper citations are part of academic integrity. Citations in CEL course materials usually follow CEL style, which is based on APA style. Your course may follow a different style. If you are uncertain which style to use for an assignment, please confirm with your instructor or TA. For further information on academic integrity, please visit the Office of Academic Integrity. Discipline Fall 2015 PHS 616 Online University of Waterloo A student is expected to know what constitutes academic integrity to avoid committing an academic offence, and to take responsibility for his/her actions. A student who is unsure whether an action constitutes an offence, or who needs help in learning how to avoid offences (e.g., plagiarism, cheating) or about rules for group work/collaboration, should seek guidance from the course instructor, academic advisor, or the undergraduate Associate Dean. For information on categories of offences and types of penalties, students should refer to Policy 71 - Student Discipline. For typical penalties, check Guidelines for the Assessment of Penalties. Appeals A decision made or penalty imposed under Policy 70 - Student Petitions and Grievances, (other than a petition) or Policy 71 - Student Discipline, may be appealed if there is a ground. A student who believes he/she has a ground for an appeal should refer to Policy 72 - Student Appeals. Grievance A student who believes that a decision affecting some aspect of his/her university life has been unfair or unreasonable may have grounds for initiating a grievance. Read Policy 70 - Student Petitions and Grievances, Section 4. When in doubt please be certain to contact the department s administrative assistant who will provide further assistance. Final Grades In accordance with Policy 19 - Access To and Release of Student Information, the Centre for Extended Learning does not release final examination grades or final course grades to students. Students must go to Quest to see all final grades. Any grades posted in Waterloo LEARN are unofficial. AccessAbility Services AccessAbility Services, located in Needles Hall, collaborates with all academic departments to arrange appropriate accommodations for students with disabilities without compromising the academic integrity of the curriculum. If you require academic accommodation to lessen the impact of your disability, please register with AccessAbility Services at the beginning of each academic term and for each course. Accessibility Statement The Centre for Extended Learning strives to meet the needs of all our online learners. Our ongoing efforts to become aligned with the Accessibility for Ontarians with Disabilities Act (AODA) are guided by University of Waterloo

AccessAbility Services Policy and the World Wide Web Consortium's (W3C) Web Content Accessibility Guidelines (WCAG) 2.0. The majority of our online courses are currently delivered via the Desire2Learn Learning Environment. Learn more about Desire2Learn s Accessibility Standards Compliance. Use of Computing and Network Resources Please see the Guidelines on Use of Waterloo Computing and Network Resources. Copyright Information UWaterloo s Web Pages All rights, including copyright, images, slides, audio, and video components, of the content of this course are owned by the course author, unless otherwise stated. These web pages are owned or controlled by the University of Waterloo, Centre for Extended Learning. By accessing the web pages, you agree that you may only download the content for your own personal, non-commercial use. You are not permitted to copy, broadcast, download, store (in any medium), transmit, show or play in public, adapt, or change in any way the content of these web pages for any other purpose whatsoever without the prior written permission of the course author and the University of Waterloo, Centre for Extended Learning. Other Sources Respect the copyright of others and abide by all copyright notices and regulations when using the computing facilities provided for your course of study by the University of Waterloo. No material on the Internet or World Wide Web may be reproduced or distributed in any material form or in any medium, without permission from copyright holders or their assignees. To support your course of study, the University of Waterloo has provided hypertext links to relevant websites, resources, and services on the web. These resources must be used in accordance with any registration requirements or conditions which may be specified. You must be aware that in providing such hypertext links, the University of Waterloo has not authorized any acts (including reproduction or distribution) which, if undertaken without permission of copyright owners or their assignees, may be infringement of copyright. Permission for such acts can only be granted by copyright owners or their assignees. If there are any questions about this notice, please contact the University of Waterloo, Centre for Extended Learning, Waterloo, Ontario, Canada, N2L 3G1 or extendedlearning@uwaterloo.ca.