International HIV workshop XI Academia Belgica, Rome September 21 st -22 nd, 2012 Organized with support of Belgian Federal Science Policy Office and Ghent University
Friday, September 21 st 2012 9:15-9:25 Opening of the meeting (Bruno Verhasselt) Discovery of HIV host protein interactions (chair Elisabetta Affabris) 9:25-9:50 Identification of HIV host cellular cofactors by RNAi in primary T lymphocytes. Veronica Iannucci (Ghent University) 9:50-10:15 Host factors implicated in CD4 downregulation and HIV infection. Alessia Landi (Ghent University) 10:15-10:45 Coffee break Nef function and cellular consequences (chair Margherita Doria) 10:45-11:10 HIV-1 Nef interferes with T lymphocyte circulation through confined environments in vivo. Andrea Imle (Hygiene Institut des Universitätsklinikums Heidelberg) 11:10-11:35 HIV-1 Nef hijacks the F-actin cytoskeleton of macrophages to trigger the 3D-invasive mesenchymal migration of infected macrophages. Christel Vérollet (IPBS-CNRS Toulouse) 11:35-12:00 Effects of heterologous membrane targeting on Nef function. Miriam Geist (Hygiene Institut des Universitätsklinikums Heidelberg) 12:00-12:25 Mechanism of deregulated T cell development and differentiation by Nef. Pieter Meuwissen (Ghent University) 12:25-12:50 Functional roles of Nef beyond HIV. Massimo Pizzato (University of Trento) 14:30-15:45 Siesta: short visit to nearby Musea (Galleria Nazionale D Arte Moderna, Borghese Gallery and Museum and park or relax in the garden 15:45-16:15 Coffee break Mechanisms in HIV infection and analogies in pathology (chair Matthias Geyer) 16:15-16:40 Human endogenous retroviruses of the HERV-W family in neurological diseases. Ninella Dolei (University of Sassari) 16:40-17:05 Mechanisms of NK cells detuning during HIV-1 infection. Margherita Doria (Bambino Gesù Children's Hospital) 17:05-17:30 The adult penile urethra is a novel entry site for HIV-1 that preferentially targets resident urethral macrophages. Morgane Bomsel (Institut Cochin, Université Paris Descartes) 17:30-17:55 Interactions between macrophages infected by HIV-1 and invasive strains of Salmonella. Chantal Deschamps (INSERM U 567, CNRS UMR 8104, Université Paris Descartes) 17:55-18:20 Molecular mechanisms of HIV genomic RNA translation. Bruno Sargueil (Université Paris Descartes) 18:20-18:45 Mechanism of exosome release in HIV and cancer. Andreas Baur (University of Erlangen)
Saturday, September 22nd, 2012 SAMHD1 in HIV infection (Chair Florence Niedergang) 9:15-9:40 SAMHD1 restricts HIV-1 infection in resting CD4+ T Cells. Oliver Keppler (University of Heidelberg, Uniklinikum Frankfurt) 9:40-10:05 Role of SAMHD1 during cell-to-cell HIV-1 transmission. Isabel Puigdomenech (Institut Pasteur, Paris) 10:05-10:30 SAMHD1's Expression Profile in Humans and Its Potential Role as a Restriction Factor for HIV-1 in Plasmacytoid Dendritic Cells. Sarah Schmidt (University of Heidelberg) 10:30-11:00 Coffee break Nef in infectivity and as a target (Chair Oliver Fackler) 11:00-11:25 HIV Nef-responsiveness is determined by the ectodomain of Env. Heinrich Gottlinger (UMass Medical School) 11:25-11:50 Characterization of HIV-1 Nef in complex with the single-domain antibody 19. Sebastian Lülf (Max-planck-Institut für molekulare Physiologie Dortmund) 11:50-12:15 Small molecule inhibition of HIV-1 Nef. Mark Verow (University of Leeds) 12:15-12:45 Closure of the meeting (Bruno Verhasselt et al.)
Participants Name First name Affiliation Address ZIP City Country Affabris Elisabetta Roma Tre University,lab.cellular microbiology Viale G. Marconi, 446 00146 Roma Italy affabris@uniroma3.it Baur Andreas University of Erlangen Hartmannstr. 14 D 91052 Erlangen Germany Andreas.Baur@uk erlangen.de Bomsel Morgane Institut Cochin, Université Paris Descartes, CNRS UMR 8104, INSERM U1016 22, rue Méchain 75014 Paris France morgane.bomsel@inserm.fr Cerboni Cristina University "La Sapienza" V.le Regina Elena 291 00161 Roma Italy cristina.cerboni@uniroma1.it Chamond Nathalie Université Paris Descartes, CNRS UMR 8015 4, Avenue de l'observatoire 75270 Paris France Deforges Jules Université Paris Descartes, CNRS UMR 8015 4, Avenue de l'observatoire 75270 Paris France Deschamps Chantal INSERM U 567, CNRS UMR 8104, Université Paris Descartes 22, rue Mechain F 75014 Paris France chantal.deschamps@inserm.fr Dolei Ninella University of Sassari Viale San Pietro '43B 7100 Sassari Italy doleivir@uniss.it Doria Margherita Bambino Gesù Children's Hospital Via Montpellier 1 00133 Roma Italy doria@uniroma2.it Fackler Oliver Hygiene Institut des Universitätsklinikums Heidelberg Im Neuenheimer Feld 326 D 69122 Heidelberg Germany Oliver.Fackler@med.uni heidelberg.de; Ferhi Cherifa INSERM U 567, CNRS UMR 8104, Université Paris Descartes 22, rue Mechain F 75014 Paris France Geist Miriam Hygiene Institut des Universitätsklinikums Heidelberg Im Neuenheimer Feld 326 D 69122 Heidelberg Germany Geyer Matthias Max planck Institut für molekulare Physiologie Otto Hahnstrasse 11 44227 Dortmund Germany matthias.geyer@mpi dortmund.mpg.de Giuliani Erica Bambino Gesù Children's Hospital Italy Gotlinger Heinrich UMass Medical School 364 Plantation Street MA 01605 Worcester USA heinrich.gottlinger@umassmed.edu Guerrero Alonso Ana Queen Mary, University of London 4 Newark Street E1 2AT London U.K. a.guerreroalonso@qmul.ac.uk Hönig Dana Max planck Institut für molekulare Physiologie Otto Hahnstrasse 11 44227 Dortmund Germany Iannucci Veronica Ghent University De Pintelaan 185 9000 Gent Belgium veronica.iannucci@ugent.be Imle Andrea Hygiene Institut des Universitätsklinikums Heidelberg Im Neuenheimer Feld 326 D 69122 Heidelberg Germany Keppler Oliver Hygiene Institut des Universitätsklinikums Heidelberg Im Neuenheimer Feld 324 D 69120 Heidelberg Germany Oliver.Keppler@kgu.de Landi Alessia Ghent University De Pintelaan 185 9000 Gent Belgium alessia.landi@ugent.be; Lülf Sebastian Max planck Institut für molekulare Physiologie Otto Hahnstrasse 11 44227 Dortmund Germany sebastian.luelf@mpi dortmund.mpg.de Mangino Giorgio Roma Tre University,lab.cellular microbiology Viale G. Marconi, 446 00146 Roma Italy gmangino@uniroma3.it Meuwissen Pieter Ghent University De Pintelaan 185 9000 Gent Belgium Pieter.Meuwissen@UGent.be Nierdergang Florence INSERM U 567, CNRS UMR 8104, Université Paris Descartes 22, rue Mechain F 75014 Paris France florence.niedergang@inserm.fr Percario Zulema A. Roma Tre University,lab.cellular microbiology Viale G. Marconi, 446 00146 Roma Italy percario@uniroma3.it Pizzato Massimo Centre for Integrative Biology, University of Trento Italy massimo.pizzato@yahoo.com Puigdomenech Isabel Institut Pasteur 28 Rue Dr Roux 75015 Paris Cedex16 France isabel.puigdomenech@pasteur.fr Sargueil Bruno Université Paris Descartes, CNRS UMR 8015 4, Avenue de l'observatoire 75270 Paris France bruno.sargueil@parisdescartes.fr Schmidt Sarah Hygiene Institut des Universitätsklinikums Heidelberg Im Neuenheimer Feld 324 D 69120 Heidelberg Germany sa.schmidt82@gmx.de
Vassena Lia Bambino Gesù Children's Hospital Italy Verhasselt Bruno Ghent University De Pintelaan 185 9000 Gent Belgium bruno.verhasselt@ugent.be Vermeire Jolien Ghent University De Pintelaan 185 9000 Gent Belgium Jolien.Vermeire@UGent.be Institut de Pharmacologie et de Biologie Structurale CNRS Verollet Christelle UMR5089 205 route de Narbonne 31077 Toulouse cedex 4 France verollet@ipbs.fr Name First name Affiliation Address ZIP City Country