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Onine Media Information www.sciencedirect.com The vita daiy source for 16 miion researchers and scientists around the gobe 70 miion pageviews each month Broad advertising product portfoio

SciVerse ScienceDirect: soving the search and discovery needs of the goba scientific research community Created to hep scientists quicky find the most reevant content for their research by offering search, reference and discovery toos, SciVerse ScienceDirect has become vita to the daiy activities of researchers across the gobe. Over the ast ten years SciVerse ScienceDirect has provided scientists and researchers with authoritative and trusted peer reviewed content and efficiency toos heping them ocate the specific knowedge needed within the rapidy growing poo of content. SciVerse ScienceDirect and Esevier: reiabe partners Esevier is recognized by the goba research community as the foremost pubisher of scientific, technica and medica fu text iterature, pubishing over 2,500 journa tites and over 11,000 onine books. Esevier is part of the Reed Esevier group. Esevier s network of sites reaches over 16 miion professionas and scientists at corporate, academic, governmenta and heath organizations. We can hep you reach reevant, targeted audiences. You can choose from a wide range of journas and branded websites where you can connect with the communities that matter most to your business. ScienceDirect.com is one of the word s most advanced web deivery systems for scientific, technica and medica information. Onine advertising at SciVerse ScienceDirect: the reevant choice The SciVerse ScienceDirect onine patform provides you a unique opportunity to target your potentia customers in their professiona context. Esevier and ScienceDirect.com can offer a forms of media incuding onine marketing to compete the 360 degree communication experience you need to stay competitive, and keep visibe with your customers. SciVerse ScienceDirect has over 70 miion pageviews and 16 miion monthy users. This provides you the voume to broadcast your message to an unprecedented number of researchers wordwide. Targeting on journa eve and country specific targeting make it possibe to reach the niche audience of your interest. A unique opportunity to deiver your brand and product messages to your customers and create ead generation. Track, optimize and change campaigns in rea time.

16 miion researchers and 70 miion pageviews each month SciVerse ScienceDirect targets 24 subject areas, 240 sub categories and over 2,500+ journas Scientific Discipines Subject Areas Sub Categories No of Journas Unique Visitors per Subject Area** Pageviews (per month)*** Life Sciences Agricutura and Bioogica Sciences 11 230 960,000 7,500,000 Biochemistry, Genetics and Moecuar Bioogy 15 363 1,710,000 14,000,000 Physica Sciences and Engineering Socia Sciences and Humanities Environmenta Science 12 150 751,000 6,000,000 Immunoogy and Microbioogy 6 139 481,000 3,750,000 Neuroscience 9 161 742,000 5,800,000 Chemica Engineering 8 122 628,000 5,000,000 Chemistry 7 162 1,050,000 8,250,000 Computer Science 12 168 517,000 3,300,000 Earth and Panetary Sciences 13 145 520,000 4,100,000 Energy 5 78 414,000 3,250,000 Engineering 13 280 925,000 7,250,000 Materias Science 9 192 844,000 6,600,000 Mathematics 14 109 292,000 2,300,000 Physics and Astronomy 10 152 592,000 4,700,000 Arts and Humanities 4 47 134,000 1,060,000 Business, Management and Accounting 9 108 527,000 4,150,000 Decision Sciences 4 61 232,000 1,825,000 Economics, Econometrics and Finance 3 97 375,000 2,950,000 Psychoogy 7 219 736,000 5,800,000 Socia Sciences 13 257 922,000 7,250,000 Heath Sciences Medicine and Dentistry 33 1061 2,100,000 17,110,000 Nursing and Heath Professions 12 149 198,000 1,600,000 Pharmacoogy, Toxicoogy and Pharmaceutica Science 5 134 670,000 5,350,000 Veterinary Science and Veterinary Medicine 3 56 180,000 1,400,000 Grand Tota 240 2,500+ 16,000,000 70,000,000 * Number of artices (End of 2009) based on interna ScienceDirect statistics. ** : Unique visitors monthy (End of 2009) as % of the tota unique visitors to ScienceDirect. Visitors visiting more than one Subcategory are ony counted once. ***: Tota pageviews per month per category (End of 2009). Pageviews reaized on journas that are part of more than one Subcategory are counted more than once.

SciVerse ScienceDirect users are your potentia audience SciVerse ScienceDirect targets the research professionas you most need to infuence: Senior management who specify and seect vendors, infuence and authorize purchase processes and decisions. Geographica profie * Professiona profie * Institutiona profie * 38% Europe 47% Researchers 35% Corporate 35% Students 12% Asia Pacific 10% ROW 40% North America 14% Teachers 4% Librarians 6% Government 10% Hospitas 49% Academic SciVerse ScienceDirect offers you an active scientific audience onine Over 70 miion page views each month on ScienceDirect.com 6 miion subscribed users and 10 miion guest users each month Average of 2.7 fu text artice downoad per session Target your preferred audience Target 1 of the 2,500 journas Target 1 of the 240 sub categories Target 1 of the 24 subject areas Target 1 of the 4 scientific discipines Run of site * Esevier study January 2010.

Onine advertising: create brand awareness or eads From standardized onine advertising campaigns to targeted, specific and excusive webinars, we can offer onine advertising products which are taiored to your needs and marketing objectives. 6 Soutions to boost brand awareness Onine advertising on SciVerse ScienceDirect is an effective way of creating brand awareness and getting attention from your target audience for your products, brands or services. 3 High Impact Banner Sizes Large, high impact position giving you an opportunity to connect with users and deiver your brand message in a contextuay reevant environment. Banner formats Leaderboard: 728X90 pixes, ScienceDirect.com, Ce.com Skyscraper: 120X600 pixes, ScienceDirect.com, Scirus.com Large Rectange: 336X280 pixes, Sciencedirect.com and Ce.com Soutions are deveoped on effective onine principes Large, high impact, IAB standard positions ensure message is ceary communicated Never more than 2 ads per page increases ad effectiveness High quaity, non-fashy / non-cutter site presentation maintains ad integrity Roadbocks Achieve a 360 degree cohesive user experience by showing your ad at the same time on both positions on a page. With 100% ownership of the page dispay ad space, you create a ongstanding impression with users. Rich Media Harness the dynamic power of Rich Media by taking advantage of the most advanced media executions. Rich Media executions invove users in a fun, exciting and engaging way, that creates a ong asting imprint in the minds of users. SciCick SciCick offers you the opportunity to deiver your message next to the reevant artices by using semantic inking. The performance based pricing mode makes this product exceptiona good vaue. ContentConnect Create awareness and educate users about your activities on a co-branded custom patform. Podcasts Fu content sponsorship opportunity that deivers a dynamic audio and video experience on seect subjects by experts. A campaigns incude traffic and campaign management Campaign metrics that are avaiabe 24/7 and paced in the right context Constanty monitor your campaign and act to optimize performance Use of DART, the word s eading ad management system from DoubeCick For more ad specifications and onine advertising opportunities pease contact your saes representative or visit www.esevierpubishingsoutions.com

Lead generation programs: generate quaified eads If your objective is to get in contact with potentia customers, SciVerse ScienceDirect ead generation programs can generate quaified eads for you. Leads can be generated in broader fieds and aso in highy targeted niche areas of your choice. These programs not ony offer eads but they aso create brand awareness and can be used when your goa is to aunch new products and test new market opportunities. Webinars An Esevier webinar is a successfu way to get significant brand exposure and the confidence of co-branding with our high quaity journas. Webinars are offered as ive audio and ive video webinars. Work with our experienced team to get great speakers on a compeing must-have topic Position your company as a thought eader Set up an educationa, informative presentation Present a rea-word case study demonstrating the success of your services Virtua Conferences Esevier conferences wi host a virtua counterpart aowing sponsors to extend their marketing reach even beyond the physica deegate base and for months after the event. Seected presentations wi be captured in high-quaity format, incuding audio and synchronized sides The virtua conference aows an extended audience to hear the atest research deveopments from top internationa speakers Virtua conferences can be viewed on demand and free of charge White Papers Researchers using SciVerse ScienceDirect are interested in more than just scientific peer reviewed artices. In order to provide those researchers with more content, a patform has been buit on which white papers can be hosted. By hosting and promoting the white papers we offer you the chance to either create awareness or get in contact with those peope who are interested in your fied of expertise and therefore in your products and services. Recruitment A new and promising proposition: Jobs for professionas in Research, Science, Technoogy and Information. The uniqueness of this service is that your jobs can be targeted in the workfow for these professionas, next to the reevant content within Sciverse ScienceDirect. Pease visit www.esevierpubishingsoutions.com for more information about optimizing your advertising revenues or contact our saes managers for the atest data, prices and offerings in your chosen market. Contact USA Esevier 360 Park Avenue South New York, NY 10010 USA commerciasaes@esevier.com +1 212 633 3100 Europe & ROW Esevier Radarweg 29 1043 NX Amsterdam The Netherands commerciasaes@esevier.com +31 20 485 3039 UK Esevier The Bouevard, Langford Lane Kidington, Oxford OX5 1GB United Kingdom commerciasaes@esevier.com +44 1865 843 868