Au front contre les maladies infectieuses et immunitaires

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1 Au front contre les maladies infectieuses et immunitaires Marc Ouellette, Ph.D., FRSC, FCAHS Chaire de Recherche du Canada sur la résistance antimicrobienne Centre Recherche en Infectiologie CHU- Québec et Université Laval Conférence- Des succès Inspirants Québec International- Université Laval 31 Janvier 2013

2 Marc Ouellette- CV DES, Collège St-Alexandre Limbour, DEC, Cegep de l Outaouais, B.Sc., Université d Ottawa, Ph.D., Université Laval, Stagiaire, Institut Pasteur, 2005 (6 mois) Post-doc, Netherlands Cancer Institute, Université Laval, CHUL, CHUQ, CHU-Québec, Directeur Scientifique, IMII-IRSC, 2010-

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4 Sequencing from man to machine

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13 Mentors and collaborators Ph.D. : Stage : Post-doc: Paul H. Roy Patrice Courvalin Piet Borst CIHR Group on Leishmania Barbara Papadopoulou, Michel J. Tremblay, Jacques Corbeil, Martin Olivier Alternative to Antimicrobials Diagnostics: Michel G. Bergeron; Bacteriocins : Ismael Fliss; Drug resistance in Leishmania USA, Canada India Colombie, Brésil France, Espagne Iran Phages: Sylvain Moineau; Microbiome Antibiotic resistance Canada

14 Research Associate Danielle Légaré Philippe Leprohon Post-docs Barbara Papadopoulou, Jingyu Wang, Christhop Kündig, Ajay K. Singh Denis Sereno Jolyne Drummelsmith Hafid Soualhine Benjamin Gourbal Aude Foucher Baptiste Vergnes Larbi Dridi Jean Michel Ubeda Jie Feng Angana Mukherjee Adriano Coelho Dewan Billal Jean-François Ritt Bédis Dridi Élodie Gazanion Isabel Vincent Rubens do Monte Neto Graduate students Danielle Légaré, Katherine Grondin, Anass Haimeur, Eric Leblanc, Christian Brochu, Chantal Guimond, Amal El Fadili, Dave Richard Paul-André Genest, François Ménard, Philippe Leprohon Karima El Fadili Dominic Gagnon Nathalie Marquis Amin Ahmed-Ouameur, Wilfried Moreira, Marie-Christine Brotherton Fereshteh Fani, Nuno Santarem, Andréanne Lupien Marie-Claude Laffitte Marie-Michelle Genois Renaud Pétry Jessica El Khoury 1st cycle : 20 7 of them did graduate work in the lab Research assistants Gaétan Roy Suzanne Avoine Marie Plourde Hélène Gingras Nadine Messier Vicky Brochu Isabel Girard Nathalie Trudel Guylaine Briand Maxime Laverdière Patrick Boucher Visiting scientists Dennis Doijes Iris Segura Javier Perez Victoria Ramtin Hadighi Angana Mukherjee Nuno Santarem Adriano Coelho Rubens Domonte Jolien Pingnet Valter Andrade Neto John Walker Chris Carter Madhubala Rentala Tom Seebeek Laurence Lachaud 19 pays différents

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17 CIHR investments in III related work

18 CIHR- reform III-Road map signature Initiatives III- Strategic Initiatives III- new strategic plan

19 III Strategic Priorities Emerging Infections and Microbial Resistance: Solutions from innovation in tools and technologies HIV/AIDS: From prevention and therapy to addressing global health challenges Immunotherapy: New approaches through systems biology Pandemic Influenza Preparedness: Prevention, therapy and public health challenges Vaccines of the 21st Century: Integrating innate and adaptive immunity and novel vaccine technologies

20 THE III STRATEGIC PLAN FOR Two overarching strategic directions Strengthening and coordinating infection and immunity research Ensuring Application and Impact of Research Two broad priority research areas Priority Research Area 1: Preparing for and responding to emerging threats emerging microbial pathogens antimicrobial resistance vaccine development improved diagnostics Priority Research Area 2: Integrating I&I knowledge in Prevention and Control of Chronic Disease inflammation human microbiome transplantation human immunology and immunotherapy environmental threats HIV/AIDS and Hepatitis C

21 Initiatives pilotées par l IMII Ongoing Initiatives Clinical Autoimmunity Novel Alternatives to Antibiotics Canada UK Partnership on Antibiotic Resistance Canadian Microbiome Initiative (RSI- intersect with ICDI) Network catalyst Meeting Planning and Dissemination (MPDs) Federal Initiatives under the leadership of III Pandemic Preparedness Strategic Research Initiative (PPSRI), PCIRN Hepatitis C Research Initiative HIV Initiatives Upcoming Initiatives Inflammation in Chronic Disease- RSI Transplantation RSI (lead) intersect with ICDI Personalized Medicine- RSI Cure HIV Pathways to Health Equity RSI Evidence Informed Health care- RSI Vaccines CHVI, ISTP-MOST Translational initiative on AMR

22 Institut des Maladies Infectieuses et Immunitaires OBIS HIV QBIS Judith Bray; assistant director Diane Christin; project officer Wendy Street; associate Jennifer Gunning; associate director Suzette Dos Santos, associate Jane Hutchinson, associate Simone Marcantonio, project officer Serge Desnoyers; assistant director Jennifer Raven, associate Mireille Perrault, executive assistant

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