Marcos Túlio Oliveira, Ph.D.

Transcription

1 CURRICULUM VITAE Marcos Túlio Oliveira, Ph.D. Contact Information Department of Technology - FCAV São Paulo State University (UNESP) Via de Acesso Prof. Paulo Donato Castellane s/n Jaboticabal, SP, Brazil Telephone: mtoliveira@fcav.unesp.br Institute of Biomedical Technology University of Tampere (UTA) Biokatu 6, FinnMedi 1 3 rd floor Tampere, Finland Telephone: marcos.oliveira@uta.fi Education : Ph.D. in Genetics, Michigan State University - East Lansing, MI, USA. Dissertation research: Roles of mtssb at the Mitochondrial DNA Replication Fork. Advisor: Laurie S. Kaguni, Ph.D : M.Sc. in Genetics and Molecular Biology with emphasis in Animal Genetics and Evolution, Universidade Estadual de Campinas - Campinas, SP, Brazil. Thesis research: [Structure and Evolution of the Mitochondrial Genome in the family Muscidae (Diptera: Calyptratae)]. Advisors: Ana Maria L. Azeredo-Espin, Ph.D., and Ana Cláudia Lessinger, Ph.D : B.S. in Biology with emphasis in Molecular Biology, Universidade Estadual de Campinas - Campinas, SP, Brazil Posts held Since 2013: Assistant Professor of Biochemistry and Molecular Biology, Departamento de Tecnologia, Universidade Estadual Paulista Jaboticabal, SP, Brazil : Post-Doctorate Fellow in Mitochondrial Biology, University of Tampere - Tampere, Finland. Project: Investigating the Roles of Respiratory Chain Alternative Enzymes in Animals. Supervisor: Howard T. Jacobs, Ph.D. Financial support: Marie Curie International Incoming Fellowship and Biocenter Finland. Activities Since October 2013: Member of the Associate Editorial Board, American Journal of Current Genetics. 1

2 September 2010-February 2011: Reviewer, scientific journal PLoS ONE. August 2010: Facilitator, orientation week for MSU International Teaching Assistants July 2010: Chair, Gordon Research Seminar on Mitochondria and Chloroplasts January-February 2010: Student representative, Admissions Committee of MSU Genetics Graduate Program August 2009: Facilitator, orientation week for MSU International Teaching Assistants April 2009: Judge, 2009 MSU Undergraduate Research and Arts Forum, poster competition on Biochemistry and Molecular Biology August 2008: Vice Chair, Gordon-Kenan Graduate Research Seminar on Mitochondria and Chloroplasts Research Interests Mitochondrial oxidative phosphorylation process. Respiratory chain alternative enzymes. Mitochondrial biology and medicine. Mechanism of mitochondrial DNA replication. Protein- DNA interactions. Protein-protein interactions at the mitochondrial DNA replication fork. Structure-function relationships in the mitochondrial replisome. Mitochondrial biogenesis: regulation of mitochondrial DNA replication and transcription. Mitochondrial genomics. Mitochondrial DNA diversity and evolution in animals. Use of mitochondrial DNA as molecular marker in genetics and evolutionary studies. Fellowships and Awards Marie Curie International Incoming Fellowship from the European Union, Postdoctoral Fellowship from Biocenter Finland, Outstanding Graduate Research Award from MSU Department of Biochemistry and Molecular Biology, April, Graduate Student Award from Sigma Xi Scientific Society Chapter MSU, November, Outstanding Graduate Student Award from MSU Genetics Graduate Program, October, Barnett Rosenberg Endowed Fellowship Award from MSU College of Natural Science, Travel Award from MSU College of Natural Science to participate in the Gordon Research Conference on Mitochondria and Chloroplasts, Biddeford, ME, USA, August 10-15, Summer Fellowship from MSU College of Natural Science, ASBMB Graduate/ Postdoctoral Travel Award to participate in the 2008 Annual Meeting of the American Society for Biochemistry and Molecular Biology, San Diego, CA, USA, April 5-9, Travel Award from MSU Genetics Graduate Program to participate in the 49 th Drosophila Research Conference, San Diego, CA, USA, April 2-6, Annual 2

3 Master Fellowship Award from the Coordenadoria de Aperfeiçoamento de Pessoal de Nível Superior (CAPES-Brazil), Prize for the poster presented at the VI Open Congress to Biology Students (CAEB), Campinas, SP, Brazil, October 6-10, Scientific Initiation Fellowship Award from the Conselho Nacional de Pesquisa e Desenvolvimento (CNPq-Brazil), Invited Talks [Mitochondria: from energy production to development of diseases]. Oliveira, MT. Presented at the 58 th National Congress of Genetics, Foz do Iguassu, PR, Brazil, September 11, [Functioning and evolution of the mitochondrial DNA replisome in metazoans]. Oliveira, MT. Presented at the Federal University of São Carlos, Sorocaba, SP, Brazil, September 21, Roles of the mitochondrial single-stranded DNA-binding protein in mitochondrial DNA replication. Oliveira, MT & Kaguni, LS. Presented at the University of Tampere BioMediTech Research Day, Tampere, Finland, December 15, Roles of the mitochondrial single-stranded DNA-binding protein in mitochondrial DNA replication. Oliveira, MT & Kaguni, LS. Presented at the Michigan State University Graduate Academic Conference, East Lansing, MI, USA, March 25, Molecular evolution and epigenetics, as part of the symposium Epigenetic Mechanisms and Cell Memory of Gene Expression Patterns. Oliveira, MT. Presented at the Annual Meeting of the Federation of Experimental Biology Societies (FeSBE), Águas de Lindóia, SP, Brazil, August 24-27, Publications McKinney, EA & Oliveira, MT (2013) Replicating animal mitochondrial DNA. Genetics and Molecular Biology, 36: Chen, S, Oliveira, MT, Sanz, A, Kemppainen, E, Fukuoh, A, Schlicht, B, Kaguni, LS & Jacobs, HT (2012) A cytoplasmic suppressor of a nuclear mutation affecting mitochondrial functions in Drosophila. Genetics, 192: Oliveira, MT & Kaguni, LS (2011) Reduced stimulation of recombinant pol γ and mitochondrial DNA (mtdna) helicase by variants of mitochondrial single-stranded DNAbinding protein (mtssb) correlates with defects in mtdna replication in animal cells. Journal of Biological Chemistry, 286: Oliveira, MT & Kaguni, LS (2010) Functional roles for the N- and C-terminal regions of the human mitochondrial single-stranded DNA-binding protein. PLoS ONE, 5(10): e doi: /journal.pone

4 Oliveira, MT, Garesse, R & Kaguni, LS (2010) Animal models of mitochondrial DNA transactions in disease and ageing. Experimental Gerontology, 45: Dallmann, HG, Tomer, G, Fackelmayer, OJ, Chen, J, Wiktor-Becker, A, Ferrara, T, Oliveira, MT, Burgers, PMJ., Kaguni, LS & McHenry, CS (2010) Parallel multiplicative target screening against diverse bacterial replicases: identification of specific inhibitors with broad spectrum potential. Biochemistry, 49: Oliveira, MT & Kaguni, LS (2009) Comparative purification strategies for Drosophila and human mitochondrial DNA replication proteins: DNA polymerase and mitochondrial singlestranded DNA-binding protein. Methods in Molecular Biology, 554: Oliveira, MT, Barau, JG, Junqueira, ACM, Feijão, PC, da Rosa, AC, Abreu, CF, Azeredo- Espin, AML & Lessinger, AC (2008) Structure and evolution of the mitochondrial genomes of Haematobia irritans and Stomoxys calcitrans: the Muscidae (Diptera: Calyptratae) perspective. Molecular Phylogenetics and Evolution, 48: Oliveira, MT, Azeredo-Espin, AML & Lessinger, AC (2007) The mitochondrial DNA control region of Muscidae flies: evolution and structural conservation in a Dipteran context. Journal of Molecular Evolution, 64: Oliveira, MT, da Rosa, AC, Azeredo-Espin, AML & Lessinger, AC (2006) Improving access to the control region and trna gene clusters of dipteran mitochondrial DNA. Journal of Medical Entomology, 43: Oliveira, MT, Azeredo-Espin, AML & Lessinger, AC (2005) Evolutionary and structural analysis of cytochrome c oxidase subunit I (COI) gene from Haematobia irritans, Stomoxys calcitrans and Musca domestica mitochondrial DNA. DNA Sequence, 16: Selected Poster Presentations Alternative oxidase and spermatogenesis in Drosophila melanogaster. Oliveira, MT, Saari, S & Jacobs, HT. Presented at the ScandoMIT, Oulu, Finland, September 18-20, Effects of the expression of the Ciona intestinalis alternative oxidase on Drosophila melanogaster. Oliveira, MT, Saari, S & Jacobs, HT. Presented at the University of Tampere BioMediTech Research Day, Tampere, Finland, December 18, Evolution of the minimal mitochondrial DNA replisome in animals. Haukka, J, Oliveira, MT & Kaguni, LS. Presented at the University of Tampere BioMediTech Research Day, Tampere, Finland, December 18, Evolution of the minimal mitochondrial DNA replisome in animals. Haukka, J, Kaguni, LS & Oliveira, MT. Presented at the 58 th National Congress of Genetics, Foz do Iguassu, PR, Brazil, September 11-14, Functional roles of the N- and C-terminal deletion mutants of the human mitochondrial singlestranded DNA-binding protein. Oliveira, MT & Kaguni, LS. Presented at the Gordon Research Conference on Mitochondria and Chloroplasts, Lucca, Italy, July 11-16,

5 Stimulation of the human mitochondrial replicase by deletion mutants of mitochondrial singlestranded DNA-binding protein. Oliveira, MT & Kaguni, LS. Presented at the Gordon Research Conference on Mitochondria and Chloroplasts, Biddeford, ME, USA, August 10-15, Stimulation of the mitochondrial replicase by deletion mutants of mitochondrial single-stranded DNA-binding protein. Oliveira, MT & Kaguni, LS. Presented at the 49 th Annual Drosophila Research Conference, San Diego, CA, USA, April 2-6, Stimulation of the human mitochondrial replicase by deletion mutants of mitochondrial singlestranded DNA-binding protein. Oliveira, MT & Kaguni, LS. Presented at the 2008 Annual Meeting of the American Society for Biochemistry and Molecular Biology, San Diego, CA, USA, April 5-9, Structure and evolution of the mitochondrial genome of the stable fly, Stomoxys calcitrans (Diptera: Muscidae). Oliveira, MT, Barau, JG, Feijão, PC, Azeredo-Espin, AML & Lessinger, AC. Presented at the 2005 Annual Meeting of Entomological Society of America, Fort Lauderdale, FL, USA, December 15-18, Teaching Experience Fall 2013: Professor - Protein Engineering (Undergraduate level), Universidade Estadual Paulista, campus Jaboticabal. Fall 2013: Professor - Applied Molecular Biology (Undergraduate level), Universidade Estadual Paulista, campus Jaboticabal. Fall 2012: Professor - BTK4300 Genes and Genomes (Graduate level), University of Tampere. Sep 2012: Visiting Professor - NG110A Advances in Mitochondrial Medicine and Biology (Graduate level), Universidade Estadual de Campinas. Fall 2007: Teaching Assistant - ZOL341 Fundamentals of Genetics (Undergraduate level), Michigan State University. Spring 2005: Teaching Assistant - BG380 Physiological and Molecular Genetics Spring 2004: Teaching Assistant - BG380 Physiological and Molecular Genetics Spring 2003: Teaching Assistant - BG380 Physiological and Molecular Genetics Fall 2001: Teaching Assistant - BB280 Basic Biochemistry (Undergraduate level), Universidade Estadual de Campinas. Memberships 2011-current: Sigma Xi Scientific Society 2009-current: American Association for the Advancement of Science 2002-current: Brazilian Society of Genetics : Entomological Society of America 5