Using Autosomal DNA to Explore Your Ancestry. Blaine T. Bettinger November 16, 2013
|
|
|
- Valerie Simon
- 7 years ago
- Views:
Transcription
1 Using Autosomal DNA to Explore Your Ancestry Blaine T. Bettinger November 16, 2013
2 Using Autosomal DNA to Explore Your Ancestry - Blaine T. Bettinger Provided only to members of the Western New York Genealogical Society (WNYGS) - Please do not share, modify, or distribute without permission from the author. For more information: - The Genetic Genealogist - 23andMe - Family Tree DNA - AncestryDNA - Trace Your Roots with DNA: Using Genetic Tests to Explore Your Family Tree by Megan Smolenyak Smolenyak and Ann Turner
3 Autosomal DNA and My Great- Grandmother s Mystery Helen Marley Johnson - b. 3 March 1889 in Mexico, NY - d. 26 Feb in Watertown, NY - Parents?
4 Autosomal DNA and My Great- Grandmother s Mystery
5 Blueprint for life DNA 23 pairs of chromosomes: o 22 pair of autosomal DNA o 1 pair of sex chromosomes Mitochondrial DNA mtdna
6 Types of Genetic Genealogy Y-DNA (the Y-chromosome) mtdna (the mitochondrial genome) Autosomal DNA (the non-sex chromosomes) X-DNA (the X-chromosome)
7 Y-DNA and mtdna tests ignore 95% of the DNA in the cell: mtdna
8 Autosomal DNA
9 The surname follows the Y-DNA! Inheritance of Y-DNA
10 Inheritance of mtdna The mtdna travels down the maternal line!
11 Me
12 Your Genetic Family Tree You have BOTH a genealogical family tree and a genetic family tree: Genealogical Tree - contains all of your ancestors Genetic Tree - contains a tiny fraction of your ancestors (only those ancestors that randomly contributed to your DNA)
13 128 ancestors at 7 generations
14 <<<128 ancestors at 7 generations
15 Graham Coop, Ph.D.
16 Your Genetic Family Tree Genetic Tree: - At 7-9 generations, genealogical ancestors fall off the Genetic Tree - Only about 475 of 1024 ancestors (or 46%) at 10 generations! - The majority of your ancestors did NOT contribute to your DNA! (Thank you to Luke Jostins and Graham Coop)
17
18 Your Autosomal DNA Genetic Tree: - Since your genetic tree is randomly inherited from your parents, even siblings will have different genetic trees! - (except identical twins)
19 Significant contributions to Genealogical Tree can be missing from your Genetic Tree:
20 Significant contributions to Genealogical Tree can be missing from your Genetic Tree: Graham Coop, Ph.D.
21 Why Test?
22 Why Test? Reason #1: Biogeographical Estimates
23 Biogeographical Estimates» Aka Ethnicity» Proprietary algorithms match segments of your DNA to reference populations from all around the world» Results are reported as percentages of DNA that aligns with each of the reference populations
24 Biogeographical Estimates 10% 10% 90% Result = AA 90%
25
26
27 Companies Differ!
28 Estimates Change!
29 Estimates Change!
30
31
32 Biogeographical Estimates The Bottom Line: - Companies use different methods to derive estimates so estimates differ - Companies refine the methods used to derive estimates so estimates change - Don t take your estimate to the bank
33 Why Test? Reason #2: Finding Genetic Cousins
34 Yes, You Share DNA With Your Family
35 Finding Genetic Cousins Company compares your DNA to the DNA of all other test-takers in the database Predicted cousins are identified Relationship Range is provided based on factors such as:» Total % of DNA shared» Size of segments shared
36 Good News!
37
38
39
40
41
42
43 Finding Genetic Cousins How reliable are relationship predictions or ranges? VERY reliable through 3 rd or 4 th cousins Difficult to predict a 5 th cousin versus a 10 th cousin (since both will share so little DNA)
44 What is the probability that my relative and I share enough DNA to be detected by DNA Testing?
45 I have a match, now what? Step 1 review the match s profile for surnames and other information Step 2 contact the match and ask if willing to share a family tree or have one online Step 3 compare family trees (names, dates, locations, etc) Step 4 identify potential common ancestors
46 Why Test? Reason #3: Health Information
47 Risks and Inherited Conditions
48 Decreased Risks
49 Traits and Drug Response
50 Health Information Can be very small risks Not deterministic (not GATTACA) The science is always changing with new research and developments GINA
51 Why Test? Reason #4: To Solve Genealogical Mysteries
52 Autosomal DNA and My Great- Grandmother s Mystery Helen Marley Johnson - b. 3 March 1889 in Mexico, NY - d. 26 Feb in Watertown, NY - Parents?
53 Autosomal DNA and My Great- Grandmother s Mystery mtdna was not helpful Can I use autosomal DNA to identify Helen s parents?
54 Autosomal DNA and My Great- Grandmother s Mystery
55 First Cousins Any shared DNA will have come from Helen and her husband!
56 Testing Procedure Use the living to recreate a lost genome: Test my father s autosomal DNA (grandchild of Helen) Test Living Walton s DNA (grandchild of Helen) Find shared DNA
57 These shared stretches of DNA were shared by siblings Roy and Esther Bettinger (from their parents) and were passed down to the next generation
58 Autosomal DNA and My Great- Grandmother s Mystery I ve identified DNA from Helen and Frank, now what? Identify shared relatives Explore shared relatives genealogies Look for clues as to Helen s ancestry Johnson surname? Located in the Oswego Co, NY area?
59 Autosomal DNA and My Great- Grandmother s Mystery The In Common With Tool:
60 Autosomal DNA and My Great- It works! Grandmother s Mystery But
61 Autosomal DNA Summary Key Points: Everyone has a Genealogical Tree AND a Genetic Tree! Useful for: - Biogeographical estimates - Identifying genetic relatives - Attacking mysteries
62 Testing Companies $99 (Autosomal, Y-DNA and mtdna SNPs) (& medical!) $99 (Autosomal DNA) $99 for Ancestry.com subscribers (Autosomal DNA only) $ (Autosomal DNA) Free $100 Restaurant.com Gift Card (until 12/31/13?)
63 Quick and painless:
64 Issues to Consider A test will not return a complete family tree (yet!) Only examines a small percentage of your genealogy (1024 ancestors at 10 generations) DNA can reveal long-hidden secrets NPEs (adoption, infidelity, name change, etc)
65 Questions?
Some ancestors are difficult to trace. Adoptions illegitimacies, name changes and migrations can present brick walls in our research that seem
Some ancestors are difficult to trace. Adoptions illegitimacies, name changes and migrations can present brick walls in our research that seem impregnable. In other cases, documentation that would shed
The sample is taken with a simple mouth swab no blood is involved. There will be instructions included on how to take the sample.
DNA testing Thanks for your enquiry about DNA testing. I oversee the Scottish DNA Project on behalf of the University of Strathclyde, Glasgow and act as representative for Family Tree DNA who host our
I Have the Results of My Genetic Genealogy Test, Now What?
I Have the Results of My Genetic Genealogy Test, Now What? Version 2.1 1 I Have the Results of My Genetic Genealogy Test, Now What? Chapter 1: What Is (And Isn t) Genetic Genealogy? Chapter 2: How Do I
GENETIC GENEALOGY AND DNA TESTING
GENETIC GENEALOGY AND DNA TESTING by Ted Steele This publication may be ordered from: St. Louis Genealogical Society P. O. Box 432010 St. Louis, MO 63143 Copyright 2013 St. Louis Genealogical Society All
Written by Roberta Estes, www.dnaexplain.com, Copyright 2007-2012
Proving Your Native American Heritage Written by Roberta Estes, www.dnaexplain.com, Copyright 2007-2012 Many American families carry oral histories of Native American heritage. Most often, we think of
DNA Testing for Genealogy - What Can It Do For You??
DNA Testing for Genealogy - What Can It Do For You?? Paper courtesy of Roberta Estes, www.dnaexplain.com, e-mail Roberta at Roberta@dnaexplain.com. Graphics courtesy of Family Tree DNA, www.familytreedna.com.
Matthew Kaplan and Taylor Edwards. University of Arizona Tucson, Arizona
Matthew Kaplan and Taylor Edwards University of Arizona Tucson, Arizona Unresolved paternity Consent for testing Ownership of Samples Uncovering genetic disorders SRY Reversal / Klinefelter s Syndrome
Family Tree FAMILY TREE GUIDE TEACHER S THE HISTORY CHANNEL PRESENTS: A two hour world premiere airing on September 17, 2001 at 9 pm ET/PT.
1 THE HISTORY CHANNEL CLASSROOM PRESENTS TEACHER S GUIDE THE HISTORY CHANNEL PRESENTS: Family Tree A two hour world premiere airing on September 17, 2001 at 9 pm ET/PT. Birth certificates. Death notices.
Marrying a relative. Is there an increased chance that a child will have genetic problems if its parents are related to each other?
Marrying a relative Is there an increased chance that a child will have genetic problems if its parents are related to each other? The simple answer to this question is Yes, there is an increased chance.
Autosomal DNA Testing. Successfully Using Autosomal Testing in Conjunction with Mitochondrial and Y-Line Testing to Address Genealogical Questions
Autosomal DNA Testing Successfully Using Autosomal Testing in Conjunction with Mitochondrial and Y-Line Testing to Address Genealogical Questions Written by Roberta Estes, www.dnaexplain.com, Copyright
Paternity Testing. Chapter 23
Paternity Testing Chapter 23 Kinship and Paternity DNA analysis can also be used for: Kinship testing determining whether individuals are related Paternity testing determining the father of a child Missing
Recovering the Romanovs
Recovering the Romanovs ACTIVITY 1 The Romanov Family: Screen #4 Inheritance of a Sex-linked Trait Key: H=normal allele; h=hemophilia allele; X=X chromosome; Y=Y chromosome 1. Use a Punnett square to show
This fact sheet describes how genes affect our health when they follow a well understood pattern of genetic inheritance known as autosomal recessive.
11111 This fact sheet describes how genes affect our health when they follow a well understood pattern of genetic inheritance known as autosomal recessive. In summary Genes contain the instructions for
Mutation and its consequences. Notes at: tcd.ie/biology_teaching_centre/local/ junior-freshman/ by1101local
Lecture 7 Mutation and its consequences CAMPBELL BIOLOGY Notes at: tcd.ie/biology_teaching_centre/local/ junior-freshman/ by1101local Natural variants and mutants 1. Genetic analysis would not be possible
DNA Testing and the Melungeons
DNA Testing and the Melungeons Roberta Estes, copyright 2006-2008, restes@comcast.net DNA testing has become an integral part of any genealogical endeavor, generally as part of a surname project. However,
Y Chromosome Markers
Y Chromosome Markers Lineage Markers Autosomal chromosomes recombine with each meiosis Y and Mitochondrial DNA does not This means that the Y and mtdna remains constant from generation to generation Except
Junior s Family Tree Inherited Traits of Animals
Junior s Family Tree Inherited Traits of Animals Objectives 1. Students will understand genetic make-up is received from both parents and is expressed by traits that can be predicted. 2. Students will
Mitochondrial DNA Analysis
Mitochondrial DNA Analysis Lineage Markers Lineage markers are passed down from generation to generation without changing Except for rare mutation events They can help determine the lineage (family tree)
MCB41: Second Midterm Spring 2009
MCB41: Second Midterm Spring 2009 Before you start, print your name and student identification number (S.I.D) at the top of each page. There are 7 pages including this page. You will have 50 minutes for
NORSE VIKING HERITAGE
NORSE VIKING HERITAGE My mother's maiden name is WILLIAMSON. Her ancestors in the paternal line came from the Shetland Islands. The Shetland Islands were settled by Norse Vikings beginning before 800 AD.
Fact Sheet 14 EPIGENETICS
This fact sheet describes epigenetics which refers to factors that can influence the way our genes are expressed in the cells of our body. In summary Epigenetics is a phenomenon that affects the way cells
Name Class Date. binomial nomenclature. MAIN IDEA: Linnaeus developed the scientific naming system still used today.
Section 1: The Linnaean System of Classification 17.1 Reading Guide KEY CONCEPT Organisms can be classified based on physical similarities. VOCABULARY taxonomy taxon binomial nomenclature genus MAIN IDEA:
Worksheet - COMPARATIVE MAPPING 1
Worksheet - COMPARATIVE MAPPING 1 The arrangement of genes and other DNA markers is compared between species in Comparative genome mapping. As early as 1915, the geneticist J.B.S Haldane reported that
SNP Essentials The same SNP story
HOW SNPS HELP RESEARCHERS FIND THE GENETIC CAUSES OF DISEASE SNP Essentials One of the findings of the Human Genome Project is that the DNA of any two people, all 3.1 billion molecules of it, is more than
BioSci 2200 General Genetics Problem Set 1 Answer Key Introduction and Mitosis/ Meiosis
BioSci 2200 General Genetics Problem Set 1 Answer Key Introduction and Mitosis/ Meiosis Introduction - Fields of Genetics To answer the following question, review the three traditional subdivisions of
Genetic Variation and Human Evolution Lynn B. Jorde, Ph.D. Department of Human Genetics University of Utah School of Medicine.
Genetic Variation and Human Evolution Lynn B. Jorde, Ph.D. Department of Human Genetics University of Utah School of Medicine. The past two decades have witnessed an explosion of human genetic data. Innumerable
Array Comparative Genomic Hybridisation (CGH)
Array Comparative Genomic Hybridisation (CGH) Exceptional healthcare, personally delivered What is array CGH? Array CGH is a new test that is now offered to all patients referred with learning disability
Population Genetics and Multifactorial Inheritance 2002
Population Genetics and Multifactorial Inheritance 2002 Consanguinity Genetic drift Founder effect Selection Mutation rate Polymorphism Balanced polymorphism Hardy-Weinberg Equilibrium Hardy-Weinberg Equilibrium
What Do I Do With My DNA Results.in 10 Easy Steps By Roberta Estes (copyright 2008)
What Do I Do With My DNA Results.in 10 Easy Steps By Roberta Estes (copyright 2008) The most common question I receive from people whose DNA results are returned to them is what do I do now? I ve put together
Recovering the Romanovs
Recovering the Romanovs Description of activity Recovering the Romanovs is an excellent opening to any unit on human genetics. To complete the three parts of this module, approximately three 40-minute
Organizing Your Paper Files Using File Folders Guide
EASY Way to Organize Family History Papers Presented by Beth Powell Susquehanna Valley Family History Conference 14 April 2012 Overview of Principles of Organization Presentation of Mary E.V. Hill s Organizing
Influence of Sex on Genetics. Chapter Six
Influence of Sex on Genetics Chapter Six Humans 23 Autosomes Chromosomal abnormalities very severe Often fatal All have at least one X Deletion of X chromosome is fatal Males = heterogametic sex XY Females
Title: Genetics and Hearing Loss: Clinical and Molecular Characteristics
Session # : 46 Day/Time: Friday, May 1, 2015, 1:00 4:00 pm Title: Genetics and Hearing Loss: Clinical and Molecular Characteristics Presenter: Kathleen S. Arnos, PhD, Gallaudet University This presentation
About The Causes of Hearing Loss
About 1 in 500 infants is born with or develops hearing loss during early childhood. Hearing loss has many causes: some are genetic (that is, caused by a baby s genes) or non-genetic (such as certain infections
You need to visit the DNA Home Page before clicking the Full Scan button to get it to scan all of your tests.
How to use the Chrome Extension for Ancestry DNA Version as of 8/28/2014: The current version is 0.6.30. Older versions won t work because Ancestry.com keeps changing their website periodically. Also,
Summary. 16 1 Genes and Variation. 16 2 Evolution as Genetic Change. Name Class Date
Chapter 16 Summary Evolution of Populations 16 1 Genes and Variation Darwin s original ideas can now be understood in genetic terms. Beginning with variation, we now know that traits are controlled by
Mendelian and Non-Mendelian Heredity Grade Ten
Ohio Standards Connection: Life Sciences Benchmark C Explain the genetic mechanisms and molecular basis of inheritance. Indicator 6 Explain that a unit of hereditary information is called a gene, and genes
Okami Study Guide: Chapter 3 1
Okami Study Guide: Chapter 3 1 Chapter in Review 1. Heredity is the tendency of offspring to resemble their parents in various ways. Genes are units of heredity. They are functional strands of DNA grouped
Meiosis is a special form of cell division.
Page 1 of 6 KEY CONCEPT Meiosis is a special form of cell division. BEFORE, you learned Mitosis produces two genetically identical cells In sexual reproduction, offspring inherit traits from both parents
Genetics 1. Defective enzyme that does not make melanin. Very pale skin and hair color (albino)
Genetics 1 We all know that children tend to resemble their parents. Parents and their children tend to have similar appearance because children inherit genes from their parents and these genes influence
The Human Genome Project
The Human Genome Project Brief History of the Human Genome Project Physical Chromosome Maps Genetic (or Linkage) Maps DNA Markers Sequencing and Annotating Genomic DNA What Have We learned from the HGP?
Elsevier Editorial System(tm) for Forensic Science International: Genetics Manuscript Draft
Elsevier Editorial System(tm) for Forensic Science International: Genetics Manuscript Draft Manuscript Number: Title: A comment on the Paper: A comparison of Y-chromosomal lineage dating using either resequencing
14.3 Studying the Human Genome
14.3 Studying the Human Genome Lesson Objectives Summarize the methods of DNA analysis. State the goals of the Human Genome Project and explain what we have learned so far. Lesson Summary Manipulating
Information leaflet. Centrum voor Medische Genetica. Version 1/20150504 Design by Ben Caljon, UZ Brussel. Universitair Ziekenhuis Brussel
Information on genome-wide genetic testing Array Comparative Genomic Hybridization (array CGH) Single Nucleotide Polymorphism array (SNP array) Massive Parallel Sequencing (MPS) Version 120150504 Design
The Human Genome. Genetics and Personality. The Human Genome. The Human Genome 2/19/2009. Chapter 6. Controversy About Genes and Personality
The Human Genome Chapter 6 Genetics and Personality Genome refers to the complete set of genes that an organism possesses Human genome contains 30,000 80,000 genes on 23 pairs of chromosomes The Human
Nevada Department of Education Standards
Blood-Typing Through an experiment with Kool-Aid, students follow the steps of the scientific method to learn about the experimental procedure of blood typing. Grade Level: 5th Objectives: Students will
Name: Class: Date: ID: A
Name: Class: _ Date: _ Meiosis Quiz 1. (1 point) A kidney cell is an example of which type of cell? a. sex cell b. germ cell c. somatic cell d. haploid cell 2. (1 point) How many chromosomes are in a human
Genetic modification for cell pedigree labels to aid disease treatment
Genetic modification for cell pedigree labels to aid disease treatment Ronald L. Rivest rivest@mit.edu March 10, 2014 Abstract We suggest modifying the human genome in order to aid in the treatment of
The Developing Person Through the Life Span 8e by Kathleen Stassen Berger
The Developing Person Through the Life Span 8e by Kathleen Stassen Berger Chapter 3 Heredity and Environment PowerPoint Slides developed by Martin Wolfger and Michael James Ivy Tech Community College-Bloomington
DNA as a Biometric. Biometric Consortium Conference 2011 Tampa, FL
DNA as a Biometric Biometric Consortium Conference 2011 Tampa, FL September 27, 2011 Dr. Peter M. Vallone Biochemical Science Division National Institute of Standards and Technology Gaithersburg, MD 20899
The correct answer is c A. Answer a is incorrect. The white-eye gene must be recessive since heterozygous females have red eyes.
1. Why is the white-eye phenotype always observed in males carrying the white-eye allele? a. Because the trait is dominant b. Because the trait is recessive c. Because the allele is located on the X chromosome
Tutorial on gplink. http://pngu.mgh.harvard.edu/~purcell/plink/gplink.shtml. PLINK tutorial, December 2006; Shaun Purcell, shaun@pngu.mgh.harvard.
Tutorial on gplink http://pngu.mgh.harvard.edu/~purcell/plink/gplink.shtml Basic gplink analyses Data management Summary statistics Association analysis Population stratification IBD-based analysis gplink
Chapter 13: Meiosis and Sexual Life Cycles
Name Period Concept 13.1 Offspring acquire genes from parents by inheriting chromosomes 1. Let s begin with a review of several terms that you may already know. Define: gene locus gamete male gamete female
Self-reported race/ethnicity in the age of genomic research: its potential impact on understanding health disparities
Mersha and Abebe Human Genomics (2015) 9:1 DOI 10.1186/s40246-014-0023-x REVIEW Open Access Self-reported race/ethnicity in the age of genomic research: its potential impact on understanding health disparities
patient education Fact Sheet PFS007: BRCA1 and BRCA2 Mutations MARCH 2015
patient education Fact Sheet PFS007: BRCA1 and BRCA2 Mutations MARCH 2015 BRCA1 and BRCA2 Mutations Cancer is a complex disease thought to be caused by several different factors. A few types of cancer
Quick Start to Family Tree
Quick Start to Family Tree Family Tree is a new way to organize and record your genealogy online. It is free, is available to everyone, and provides an easy way to discover your place in history with free
UNIT 13 (OPTION) Genetic Abnormalities
Unit 13 Genetic Abnormailities 1 UNIT 13 (OPTION) Genetic Abnormalities Originally developed by: Hildur Helgedottir RN, MN Revised (2000) by: Marlene Reimer RN, PhD, CCN (C) Associate Professor Faculty
GAW 15 Problem 3: Simulated Rheumatoid Arthritis Data Full Model and Simulation Parameters
GAW 15 Problem 3: Simulated Rheumatoid Arthritis Data Full Model and Simulation Parameters Michael B Miller , Michael Li , Gregg Lind , Soon-Young
X Linked Inheritance
X Linked Inheritance Information for Patients and Families 2 X linked Inheritance The following will give you information about what X linked inheritance means and how X linked conditions are inherited.
Follow your family using census records
Census records are one of the best ways to discover details about your family and how that family changed every 10 years. You ll discover names, addresses, what people did for a living, even which ancestor
KEY TIPS FOR CENSUS SUCCESS
KEY TIPS FOR CENSUS SUCCESS We're going to begin with tips that apply whichever census you're searching, and whichever site you're using. * Always allow for mistakes - for example, it's rarely advisable
February 27, 2008. Welcome to the Family Tree Maker Users Group!
February 27, 2008 Welcome to the Family Tree Maker Users Group! Powerful genealogy information management, easy-to-use research tools, and creative output options make Family Tree Maker the most complete
List of United States Presidents by genealogical
List of United States Presidents by genealogical relationship From Wikipedia, the free encyclopedia This page discusses some of the genealogical relationships of, and among, Presidents of the United States.
Digging into Ancestral Roots
Algonquin College of Applied Arts & Technology Digging into Ancestral Roots Business Administration - Core Course Number: Co-Requisites: Pre-Requisites: GED5009 N/A N/A Applicable Program(s): AAL: Core/Elective:
The Genetic Connection
Vol. 11, Issue 1, Winter 2009 The Genetic Connection Cooling Program Application Brighter Tomorrow Grant Recipients 1-888-MSFOCUS (673-6287) www.msfocus.org Publishing Coordinator Terry Schenker Editorial
Section 3 Comparative Genomics and Phylogenetics
Section 3 Section 3 Comparative enomics and Phylogenetics At the end of this section you should be able to: Describe what is meant by DNA sequencing. Explain what is meant by Bioinformatics and Comparative
Patient Information. for Childhood
Patient Information Genetic Testing for Childhood Hearing Loss Introduction This document describes the most common genetic cause of childhood hearing loss and explains the role of genetic testing. Childhood
Human Blood Types: Codominance and Multiple Alleles. Codominance: both alleles in the heterozygous genotype express themselves fully
Human Blood Types: Codominance and Multiple Alleles Codominance: both alleles in the heterozygous genotype express themselves fully Multiple alleles: three or more alleles for a trait are found in the
PRACTICE PROBLEMS - PEDIGREES AND PROBABILITIES
PRACTICE PROBLEMS - PEDIGREES AND PROBABILITIES 1. Margaret has just learned that she has adult polycystic kidney disease. Her mother also has the disease, as did her maternal grandfather and his younger
Algorithms in Computational Biology (236522) spring 2007 Lecture #1
Algorithms in Computational Biology (236522) spring 2007 Lecture #1 Lecturer: Shlomo Moran, Taub 639, tel 4363 Office hours: Tuesday 11:00-12:00/by appointment TA: Ilan Gronau, Taub 700, tel 4894 Office
ARTICLE The Genetic Ancestry of African Americans, Latinos, and European Americans across the United States
ARTICLE The Genetic Ancestry of African Americans, Latinos, and European Americans across the United States Katarzyna Bryc, 1,2, * Eric Y. Durand, 2 J. Michael Macpherson, 3 David Reich, 1,4,5 and Joanna
SCHOOL OF MEDICAL RADIOGRAPHY GENERAL APPLICANT INSTRUCTIONS (13)
SCHOOL OF MEDICAL RADIOGRAPHY GENERAL APPLICANT INSTRUCTIONS (13) 1. Read all attached materials. Applications received by 10-30-12 will be considered for admission to the 2013 class. Applications received
Gene Therapy and Genetic Counseling. Chapter 20
Gene Therapy and Genetic Counseling Chapter 20 What is Gene Therapy? Treating a disease by replacing, manipulating or supplementing a gene The act of changing an individual s DNA sequence to fix a non-functional
Life Insurance. What you need to know about. Mucopolysaccharide and related diseases including Fabry disease
Society for Mucopolysaccharide Diseases MPS House, Repton Place White Lion Road, Amersham Buckinghamshire, HP7 9LP, UK 0345 389 9901 mps@mpssociety.org.uk www.mpssociety.org.uk Mucopolysaccharide and related
Heredity. Sarah crosses a homozygous white flower and a homozygous purple flower. The cross results in all purple flowers.
Heredity 1. Sarah is doing an experiment on pea plants. She is studying the color of the pea plants. Sarah has noticed that many pea plants have purple flowers and many have white flowers. Sarah crosses
Forensic DNA Testing Terminology
Forensic DNA Testing Terminology ABI 310 Genetic Analyzer a capillary electrophoresis instrument used by forensic DNA laboratories to separate short tandem repeat (STR) loci on the basis of their size.
Development of two Novel DNA Analysis methods to Improve Workflow Efficiency for Challenging Forensic Samples
Development of two Novel DNA Analysis methods to Improve Workflow Efficiency for Challenging Forensic Samples Sudhir K. Sinha, Ph.D.*, Anne H. Montgomery, M.S., Gina Pineda, M.S., and Hiromi Brown, Ph.D.
Chapter 13: Meiosis and Sexual Life Cycles
Name Period Chapter 13: Meiosis and Sexual Life Cycles Concept 13.1 Offspring acquire genes from parents by inheriting chromosomes 1. Let s begin with a review of several terms that you may already know.
A trait is a variation of a particular character (e.g. color, height). Traits are passed from parents to offspring through genes.
1 Biology Chapter 10 Study Guide Trait A trait is a variation of a particular character (e.g. color, height). Traits are passed from parents to offspring through genes. Genes Genes are located on chromosomes
Biology Behind the Crime Scene Week 4: Lab #4 Genetics Exercise (Meiosis) and RFLP Analysis of DNA
Page 1 of 5 Biology Behind the Crime Scene Week 4: Lab #4 Genetics Exercise (Meiosis) and RFLP Analysis of DNA Genetics Exercise: Understanding how meiosis affects genetic inheritance and DNA patterns
Terms: The following terms are presented in this lesson (shown in bold italics and on PowerPoint Slides 2 and 3):
Unit B: Understanding Animal Reproduction Lesson 4: Understanding Genetics Student Learning Objectives: Instruction in this lesson should result in students achieving the following objectives: 1. Explain
Investigating the genetic basis for intelligence
Investigating the genetic basis for intelligence Steve Hsu University of Oregon and BGI www.cog-genomics.org Outline: a multidisciplinary subject 1. What is intelligence? Psychometrics 2. g and GWAS: a
DRAGON GENETICS LAB -- Principles of Mendelian Genetics
DragonGeneticsProtocol Mendelian Genetics lab Student.doc DRAGON GENETICS LAB -- Principles of Mendelian Genetics Dr. Pamela Esprivalo Harrell, University of North Texas, developed an earlier version of
From Africa to Aotearoa Part 1: Out of Africa
From Africa to Aotearoa Part 1: Out of Africa The spread of modern humans out of Africa started around 65,000 years ago, and ended with the settlement of New Zealand 750 years ago. These PowerPoint presentations
SAP HANA Enabling Genome Analysis
SAP HANA Enabling Genome Analysis Joanna L. Kelley, PhD Postdoctoral Scholar, Stanford University Enakshi Singh, MSc HANA Product Management, SAP Labs LLC Outline Use cases Genomics review Challenges in
Genetics Review for USMLE (Part 2)
Single Gene Disorders Genetics Review for USMLE (Part 2) Some Definitions Alleles variants of a given DNA sequence at a particular location (locus) in the genome. Often used more narrowly to describe alternative
A Guide to Family Health History
1 Does it Run in the Family? A Guide to Family Health History genetic alliance Contents This toolkit will help you collect, organize, and understand your family health history. In Book 1: A Guide to Family
Two copies of each autosomal gene affect phenotype.
SECTION 7.1 CHROMOSOMES AND PHENOTYPE Study Guide KEY CONCEPT The chromosomes on which genes are located can affect the expression of traits. VOCABULARY carrier sex-linked gene X chromosome inactivation
BOY SCOUTS OF AMERICA MERIT BADGE SERIES GENEALOGY
GENEALOGY BOY SCOUTS OF AMERICA MERIT BADGE SERIES GENEALOGY Enhancing our youths competitive edge through merit badges Requirements 1. Explain to your counselor what the words genealogy, ancestor, and
Family Tree Maker 2011 VERSION 16 UPGRADE GUIDE
Family Tree Maker 2011 VERSION 16 UPGRADE GUIDE Copyright 2011 Ancestry.com Inc. 360 West 4800 North Provo, Utah 84604 All rights reserved. Ancestry.com and Family Tree Maker are registered trademarks
302. Online Family Trees
302. Online Family Trees By Lesly Klippel The proliferation of web sites that enable you to upload your family history makes keeping your family tree on the Internet very popular, safe and convenient.
Known Donor Questionnaire
Known Donor Questionnaire Your donor s answers to these questions will provide you with a wealth of information about his health. You ll probably need assistance from a health care provider to interpret
PRINCIPLES OF POPULATION GENETICS
PRINCIPLES OF POPULATION GENETICS FOURTH EDITION Daniel L. Hartl Harvard University Andrew G. Clark Cornell University UniversitSts- und Landesbibliothek Darmstadt Bibliothek Biologie Sinauer Associates,
Cancer Genomics: What Does It Mean for You?
Cancer Genomics: What Does It Mean for You? The Connection Between Cancer and DNA One person dies from cancer each minute in the United States. That s 1,500 deaths each day. As the population ages, this
Got Lactase? The Co-evolution of Genes and Culture
The Making of the Fittest: Natural The Making Selection of the and Fittest: Adaptation Natural Selection and Adaptation OVERVIEW PEDIGREES AND THE INHERITANCE OF LACTOSE INTOLERANCE This activity serves
Chromosomal Basis of Inheritance. Ch. 3
Chromosomal Basis of Inheritance Ch. 3 THE CHROMOSOME THEORY OF INHERITANCE AND SEX CHROMOSOMES! The chromosome theory of inheritance describes how the transmission of chromosomes account for the Mendelian
somatic cell egg genotype gamete polar body phenotype homologous chromosome trait dominant autosome genetics recessive
CHAPTER 6 MEIOSIS AND MENDEL Vocabulary Practice somatic cell egg genotype gamete polar body phenotype homologous chromosome trait dominant autosome genetics recessive CHAPTER 6 Meiosis and Mendel sex
DNA paternity and relationship testing services
analytical quality measurement accuracy regulatory testing chemical measurement bioanalysis standards forensic testing DNA paternity and relationship testing services Contents 1 Why choose LGC to carry
Answer Key. Vocabulary Practice
Answer Key Vocabulary Practice Copyright by McDougal Littell, a division of Houghton Mifflin Company A. Categorize Words 1. organism, L; cell, L; species, L; transgenic, B; biotechnology, T; molecular
Chapter 9 Patterns of Inheritance
Bio 100 Patterns of Inheritance 1 Chapter 9 Patterns of Inheritance Modern genetics began with Gregor Mendel s quantitative experiments with pea plants History of Heredity Blending theory of heredity -