CURRICULUM VITAE. Douglas A. Fantz

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1 CURRICULUM VITAE Douglas A. Fantz Date and place of birth: Personal: Address: August 10, 1971; Chicago, Illinois Married, three children Agnes Scott College Department of Chemistry 141 E. College Ave. Decatur, GA Telephone: (404) FAX: (404) Educational Background: University of South Carolina (Columbia, SC) Ph.D. June 1998, Biochemistry Department of Chemistry and Biochemistry Faculty Advisor: Dr. Steve Kistler Furman University (Greenville, SC) Bachelor of Science, Biochemistry Faculty Advisor: Dr. John Wheeler Research Experience: 2010-present Associate Professor. Caenorhabditis elegans development. Biochemical and genetic investigations of the Ras-signaling pathway during C. elegans vulval development. Involvement of Rab proteins during Ras-mediated signaling and investigations of the function and regulation of transcription factor effectors. Department of Chemistry, Agnes Scott College, Decatur, GA Assistant Professor. Caenorhabditis elegans development. Department of Chemistry, Agnes Scott College, Decatur, GA Assistant Professor. Caenorhabditis elegans development. Department of Biology, Wake Forest University, Winston-Salem, NC Postdoctoral Fellow. Caenorhabditis elegans development. Genetic and biochemical investigations of the Ras-signaling pathway during C. elegans vulval development. Dr. Kerry Kornfeld. Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, MO Doctoral Student. Gene Expression. Characterization of the Promoter Region of the Rat Testis-Specific Histone H1t Gene. Dr. Steve Kistler.

2 Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC Undergraduate research and thesis. Analytical Chemistry. Separation of biomolecules using capillary electrophoresis. Dr. John Wheeler. Department of Chemistry, Furman University, Greenville, SC. Academic Positions: Fall 2014-present 2010-present President of the Faculty Executive Committee, Agnes Scott College, Decatur, GA Associate Professor and Chair, Agnes Scott College, Decatur, GA., Department of Chemistry Assistant Professor, Agnes Scott College, Decatur, GA., Department of Chemistry Assistant Professor, Wake Forest University, Winston-Salem, NC., Department of Biology Faculty, Washington University, University College, St. Louis, MO., Department of Biology Supervising Instructor, University College, St. Louis, MO., Department of Biology, Advanced Topics in Genetics Teaching Assistant Supervisor, University of South Carolina, Columbia, SC., Department of Chemistry, General Chemistry Teaching Assistant, University of South Carolina, Columbia, SC., Department of Chemistry, General Chemistry Laboratory Assistant, University of South Carolina, Columbia, SC., Department of Chemistry, Organic Chemistry Teaching Assistant, University of South Carolina, Columbia, SC., Department of Chemistry, Honors General Chemistry Informal teaching activities: Washington University School of Medicine, St. Louis, MO., Department of Molecular Biology and Pharmacology. Supervised undergraduate thesis project Guest lecturer, University of South Carolina, Columbia, SC., Biochemistry lectures for Honors General Chemistry class.

3 Awards and Fellowships: Previous: 12/15/09 12/14/12 NSF MRI-R2: Acquisition of quantitative instrumentation for research in molecular biology and biochemistry. Agnes Scott College, co-pi Dr. Timothy Finco, Amount of award $127,172. 9/1/07 8/31/11 NIH Academic Research Enhancement Award (R15), Characterization of a novel substrate of ERK MAP kinase that functions during vulval development in Caenorhabditis elegans." Agnes Scott College, Amount of award $199, Goizueta Foundation Collaborative Research Grant, Determination of the transactivation potential of the T08D10.1 transcription factor. Agnes Scott College, Amount of award $ Julia Gary Summer Collaborative Research Grant, Characterization of Excretory Cell Development in rab-8 mutants. Agnes Scott College, Amount of award $ Goizueta Foundation Collaborative Research Grant, Investigation of the MAP kinase docking site domains in the C. elegans protein, Mks- 1. Agnes Scott College, Amount of award $ Goizueta K-12 Outreach Grant, Proposal to Fund an Undergraduate Coordinator of Chemical Demonstrations. Agnes Scott College, Amount of award $ Julia Gary Summer Collaborative Research Grant, Purification and characterization of the C. elegans gene, mks-1. Agnes Scott College, Amount of award $5, Cross Campus Cancer Research Grant, Identification of Downstream Targets of the Caenorhabditis elegans lin-1 Gene Using Microarray Analysis. Wake Forest School of Medicine. Amount of award $10, Cross Campus Collaborative Research Fund, Genetic Screen for Regulators of Hypoxia Tolerance. Co-PI with Costas Koumenis, Wake Forest School of Medicine. Amount of award, $14, Science Research Fund, Genetic Characterization of the C. elegans gene, T08D10.1. Wake Forest University. Amount of award, $9, NIH Postdoctoral Fellowship Training Grant, Individual National Research Service Award, Investigations of the ETS Protein, LIN-1. Washington University School of Medicine. Amount of award, $87,604

4 1997 Durig Travel Award, American Society for Cellular Biology Department of Education Graduate Fellowship 1992 Furman Advantage Undergraduate Research Fellowship Publications: Leight, E.R., Murphy, J.T., Fantz, D.A., Pepin, D., Schneider, D.L., Ratliff, T.M., Mohammad, D.H., Herman, M., and Kornfeld, K. (2015) Conversion of the LIN-1 ETS Protein of Caenorhabditis elegans from a Sumoylated Transcriptional Repressor to a Phosphorylated Transcriptional Activator. Genetics. Jan 7. pii: genetics [Epub ahead of print] Smith, D.R., Stokes, M., Aklilu, S., Zobel, C., Kornfeld, K., Fantz, D.A. Identification of Caenorhabditis elegans rab-8 as an essential gene involved in vulval development. In preparation. Miley, G.R., Fantz, D.A., Glossip, D., Lu, X., Saito, R.M., Palmer, R.E., Inoue, T., van den Heuvel, S., Sternberg, P.W., and Kornfeld, K. (2004) Identification of Residues of the Caenorhabditis elegans LIN-1 ETS Domain That Are Necessary for DNA Binding and Regulation of Vulval Cell Fates. Genetics 167: Fantz, D.A., Jacobs, D., Glossip, D., and Kornfeld, K. (2001) Docking sites on substrate proteins direct extracellular signal-regulated kinase (ERK) to phosphorylate specific residues. J. Biol. Chem. 276, Fantz, D.A., Hatfield, W.R., Horvath, G., Kistler, M.K., and Kistler, W.S. (2001) Mice with a targeted disruption of the H1t gene are fertile and undergo normal changes in structural chomosomal proteins during spermiogenesis. Biol. Reprod. 64, Bartell, J.G., Fantz, D.A., Davis, T., Dewey, M.J., Kistler, M.K., and Kistler, W.S. (2000) Elimination of male germ cells in transgenic mice by the diptheria toxin A chain gene directed by the histone H1t promoter. Biol. Reprod. 63, Fantz, D.A. (1998) Characterization of the Promoter Region of the Rat Testis-Specific Histone H1t Gene. Ph.D. Dissertation. Clare, S.E., Fantz, D.A., Kistler, W.S., and Kistler, M.K. (1997) The Testis-Specific Histone H1t Gene Is Strongly Repressed by a G/C-rich Region just Downstream of the TATA Box. J. Biol. Chem. 272, Clare, S.E., Hatfield, W.R., Fantz, D.A., Kistler, W.S., and Kistler, M.K. (1997) Characterization of the promoter for the spermatocyte-specific histone H1t gene. Biol. Reprod. 56, Selected Abstracts (national and international meetings): Stokes, M., Aklilu, S., Edwards, S., Fantz, D.A. (2009) T08D10.1, a novel mediator of Ras signaling during vulval development. 17 th International C. elegans Meeting. Los Angeles, CA.

5 Fantz, D.A., Frempong, A., Hanks, A., Edwards, S., Powers, C. (2007) Tag-295/T08D10.1 acts as a substrate of ERK MAP kinase tosuppress vulval development. 16 th International C. elegans Meeting. Los Angeles, CA. Frempong, A.F., Powers, C., Edwards, S., and Fantz, D.A. (2006) Analysis of the C. elegans protein, Mks-1: A suppressor of Ras signaling. 231 st National Meeting of the American Chemical Society, Atlanta, GA. Fantz, D.A. and Smith R. (2005) Identification of downstream targets of the gene C. elegans lin- 1 using microarray analysis. 15 th International Worm Meeting. Los Angeles, CA. Fantz, D.A., Smith, R., Zobel, C., Glossip, D., and Kornfeld, K. (2003) Identification of C. elegans rab-8 as an essential gene involved in vulval development. 14 th International Worm Meeting. Los Angeles, CA. Fantz, D.A., Zobel, C., and Kornfeld, K. (2002) Identification of C. elegans rab-8 as an essential gene involved in vulval development. Midwest Worm Meeting. St. Louis, MO. Fantz, D.A., Jacobs, D., Glossip, D., and Kornfeld, K. (2001) Docking sites on substrate proteins direct extracellular signal-regulated kinase (ERK) to phosphorylate specific residues. 13 th International Worm Meeting. Los Angeles, CA. Fantz, D.A., Jacobs, D., and Kornfeld, K. (2000) ERK MAP Kinase recognition of substrates is mediated by a modular system of docking sites that directs phosphorylation at specific residues. Midwest Worm Meeting. Minneapolis, MN. Fantz, D.A. and Kornfeld, K. (1999) Biochemical and Genetic Studies of the ETS-Domain Protein, LIN th International C. elegans Meeting. Madison, WI. Fantz, D.A., Clare, S.E., Kistler, M.K., and Kistler, W.S. (1997) Identification of Binding Factors for the Inhibitory GC Box2 of the Rat H1t Promoter. ASBMB. Washington D.C. Student Researchers (past and present): Graduate Students : Ryan Smith graduate student at Wake Forest University: awarded master s degree in Biology (April 2006). Thesis title: Identification of Dowstream Targets of the Caenorhabditis elegans LIN-1 Transcription Factor using Microarray Analysis. Agnes Scott College Undergraduate Researchers : Pamela Guinn, Chinenyenwa Okoye, and Myat Win : Katherine Wilson and Yiyi Shen : Morghan Pendergrass : Segen Aklilu and Michelle Stokes : Soojin Yim, Segen Aklilu, Shannon Reisner : Sarah Edwards, Diane Smith, Christy Powers, Aly Spinner : Abena Frempong, Moutushi Rahman, Michelle Nguyen Wake Forest University Undergraduate Researchers : Julia Ham, Jennifer Bernet Summer : Weston Saunders, Jared Manse, Amanda Hanks