International HIV workshop XI. Academia Belgica, Rome
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1 International HIV workshop XI Academia Belgica, Rome September 21 st -22 nd, 2012 Organized with support of Belgian Federal Science Policy Office and Ghent University
2 Friday, September 21 st :15-9:25 Opening of the meeting (Bruno Verhasselt) Discovery of HIV host protein interactions (chair Elisabetta Affabris) 9:25-9:50 Identification of HIV host cellular cofactors by RNAi in primary T lymphocytes. Veronica Iannucci (Ghent University) 9:50-10:15 Host factors implicated in CD4 downregulation and HIV infection. Alessia Landi (Ghent University) 10:15-10:45 Coffee break Nef function and cellular consequences (chair Margherita Doria) 10:45-11:10 HIV-1 Nef interferes with T lymphocyte circulation through confined environments in vivo. Andrea Imle (Hygiene Institut des Universitätsklinikums Heidelberg) 11:10-11:35 HIV-1 Nef hijacks the F-actin cytoskeleton of macrophages to trigger the 3D-invasive mesenchymal migration of infected macrophages. Christel Vérollet (IPBS-CNRS Toulouse) 11:35-12:00 Effects of heterologous membrane targeting on Nef function. Miriam Geist (Hygiene Institut des Universitätsklinikums Heidelberg) 12:00-12:25 Mechanism of deregulated T cell development and differentiation by Nef. Pieter Meuwissen (Ghent University) 12:25-12:50 Functional roles of Nef beyond HIV. Massimo Pizzato (University of Trento) 14:30-15:45 Siesta: short visit to nearby Musea (Galleria Nazionale D Arte Moderna, Borghese Gallery and Museum and park or relax in the garden 15:45-16:15 Coffee break Mechanisms in HIV infection and analogies in pathology (chair Matthias Geyer) 16:15-16:40 Human endogenous retroviruses of the HERV-W family in neurological diseases. Ninella Dolei (University of Sassari) 16:40-17:05 Mechanisms of NK cells detuning during HIV-1 infection. Margherita Doria (Bambino Gesù Children's Hospital) 17:05-17:30 The adult penile urethra is a novel entry site for HIV-1 that preferentially targets resident urethral macrophages. Morgane Bomsel (Institut Cochin, Université Paris Descartes) 17:30-17:55 Interactions between macrophages infected by HIV-1 and invasive strains of Salmonella. Chantal Deschamps (INSERM U 567, CNRS UMR 8104, Université Paris Descartes) 17:55-18:20 Molecular mechanisms of HIV genomic RNA translation. Bruno Sargueil (Université Paris Descartes) 18:20-18:45 Mechanism of exosome release in HIV and cancer. Andreas Baur (University of Erlangen)
3 Saturday, September 22nd, 2012 SAMHD1 in HIV infection (Chair Florence Niedergang) 9:15-9:40 SAMHD1 restricts HIV-1 infection in resting CD4+ T Cells. Oliver Keppler (University of Heidelberg, Uniklinikum Frankfurt) 9:40-10:05 Role of SAMHD1 during cell-to-cell HIV-1 transmission. Isabel Puigdomenech (Institut Pasteur, Paris) 10:05-10:30 SAMHD1's Expression Profile in Humans and Its Potential Role as a Restriction Factor for HIV-1 in Plasmacytoid Dendritic Cells. Sarah Schmidt (University of Heidelberg) 10:30-11:00 Coffee break Nef in infectivity and as a target (Chair Oliver Fackler) 11:00-11:25 HIV Nef-responsiveness is determined by the ectodomain of Env. Heinrich Gottlinger (UMass Medical School) 11:25-11:50 Characterization of HIV-1 Nef in complex with the single-domain antibody 19. Sebastian Lülf (Max-planck-Institut für molekulare Physiologie Dortmund) 11:50-12:15 Small molecule inhibition of HIV-1 Nef. Mark Verow (University of Leeds) 12:15-12:45 Closure of the meeting (Bruno Verhasselt et al.)
4 Participants Name First name Affiliation Address ZIP City Country Affabris Elisabetta Roma Tre University,lab.cellular microbiology Viale G. Marconi, Roma Italy Baur Andreas University of Erlangen Hartmannstr. 14 D Erlangen Germany Andreas.Baur@uk erlangen.de Bomsel Morgane Institut Cochin, Université Paris Descartes, CNRS UMR 8104, INSERM U , rue Méchain Paris France [email protected] Cerboni Cristina University "La Sapienza" V.le Regina Elena Roma Italy [email protected] Chamond Nathalie Université Paris Descartes, CNRS UMR , Avenue de l'observatoire Paris France Deforges Jules Université Paris Descartes, CNRS UMR , Avenue de l'observatoire Paris France Deschamps Chantal INSERM U 567, CNRS UMR 8104, Université Paris Descartes 22, rue Mechain F Paris France [email protected] Dolei Ninella University of Sassari Viale San Pietro '43B 7100 Sassari Italy [email protected] Doria Margherita Bambino Gesù Children's Hospital Via Montpellier Roma Italy [email protected] Fackler Oliver Hygiene Institut des Universitätsklinikums Heidelberg Im Neuenheimer Feld 326 D Heidelberg Germany [email protected] heidelberg.de; Ferhi Cherifa INSERM U 567, CNRS UMR 8104, Université Paris Descartes 22, rue Mechain F Paris France Geist Miriam Hygiene Institut des Universitätsklinikums Heidelberg Im Neuenheimer Feld 326 D Heidelberg Germany Geyer Matthias Max planck Institut für molekulare Physiologie Otto Hahnstrasse Dortmund Germany matthias.geyer@mpi dortmund.mpg.de Giuliani Erica Bambino Gesù Children's Hospital Italy Gotlinger Heinrich UMass Medical School 364 Plantation Street MA Worcester USA [email protected] Guerrero Alonso Ana Queen Mary, University of London 4 Newark Street E1 2AT London U.K. [email protected] Hönig Dana Max planck Institut für molekulare Physiologie Otto Hahnstrasse Dortmund Germany Iannucci Veronica Ghent University De Pintelaan Gent Belgium [email protected] Imle Andrea Hygiene Institut des Universitätsklinikums Heidelberg Im Neuenheimer Feld 326 D Heidelberg Germany Keppler Oliver Hygiene Institut des Universitätsklinikums Heidelberg Im Neuenheimer Feld 324 D Heidelberg Germany [email protected] Landi Alessia Ghent University De Pintelaan Gent Belgium [email protected]; Lülf Sebastian Max planck Institut für molekulare Physiologie Otto Hahnstrasse Dortmund Germany sebastian.luelf@mpi dortmund.mpg.de Mangino Giorgio Roma Tre University,lab.cellular microbiology Viale G. Marconi, Roma Italy [email protected] Meuwissen Pieter Ghent University De Pintelaan Gent Belgium [email protected] Nierdergang Florence INSERM U 567, CNRS UMR 8104, Université Paris Descartes 22, rue Mechain F Paris France [email protected] Percario Zulema A. Roma Tre University,lab.cellular microbiology Viale G. Marconi, Roma Italy [email protected] Pizzato Massimo Centre for Integrative Biology, University of Trento Italy [email protected] Puigdomenech Isabel Institut Pasteur 28 Rue Dr Roux Paris Cedex16 France [email protected] Sargueil Bruno Université Paris Descartes, CNRS UMR , Avenue de l'observatoire Paris France [email protected] Schmidt Sarah Hygiene Institut des Universitätsklinikums Heidelberg Im Neuenheimer Feld 324 D Heidelberg Germany [email protected]
5 Vassena Lia Bambino Gesù Children's Hospital Italy Verhasselt Bruno Ghent University De Pintelaan Gent Belgium Vermeire Jolien Ghent University De Pintelaan Gent Belgium Institut de Pharmacologie et de Biologie Structurale CNRS Verollet Christelle UMR route de Narbonne Toulouse cedex 4 France [email protected] Name First name Affiliation Address ZIP City Country
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