UW Center for Genomics & Public Health

Transcription

1 UW Center for Genomics & Public Health Karen L. Edwards, PhD Director Department of Epidemiology and Institute for Public Health Genetics School of Public Health and Community Medicine University of Washington

2 Centers for Genomics Three Centers & Public Health University of Michigan University of North Carolina University of Washington Funding Three year cooperative agreement with ASPH/CDC/ATSDR

3 Current Partners National Centers for Disease Control and Prevention Office of Genomics and Disease Prevention Regional Center for Ecogenetics & Environmental Health ELSI Core Northwest Cancer Genetics Network Northwest Center for Public Health Practice Washington State Department of Health Office of Community Wellness and Prevention Genetic Services Section

4 Mission To integrate advances in genetic technology into public health practice and offer research & educational opportunities for public health students and professionals.

5 Center Goals Knowledge Base Development Evaluate & contribute to the knowledge base on genomics & public health. Technical Assistance Provide technical assistance to local, state, & regional public health organizations. Training Develop & provide training for current & future public health work force.

6 UW Working Groups Asthma Led by Wylie Burke Diabetes, type 1 & type 2 Led by Karen Edwards Familial Hypercholesterolemia (FH) Led by Melissa Austin

7 Knowledge Base Asthma Burke W, Fesinmeyer M, Reed K, et al. Family history as a predictor of asthma AJPM 2003;24: Burke W. Family history as a potential tool in asthma prevention. (presentation) Reed EK, Burke W, Edwards KL. Genetic polymorphisms of the IgE-dependent inflammatory pathway and atopic asthma. (HuGE review, in progress) Asthma & Genomics: Implications for Public Health. (in progress)

8 Knowledge Base (cont.) Diabetes Harrison TA, Hindorff LA, Kim H, et al. Family history of diabetes as a potential public health tool AJPM 2003;24: Edwards KL. Can family history of type 2 diabetes be used as a tool for public health? (presentation) Wines RCM, Edwards K, Burns-McGrath B. Hepatocyte nuclear factor I-Alpha and maturity onset diabetes of the young type 3. (HuGE Review, in progress) Cross J, Kang A, Sieh W, et al. An analytic framework for evaluating newborn screening for type 1 diabetes. (in progress)

9 Knowledge Base (cont.) Familial Hypercholesterolemia Austin MA, Zimmern RL, Humphries SE. High "population attributable fraction" for coronary heart disease mortality among relatives in monogenic familial hypercholesterolemia Genet Med 2002;4: Austin MA, Hutter C, Zimmern RL, Humphries SE. Genetic causes of monogenic heterozygous familial hypercholesterolemia: a HuGE prevalence review. (HuGE review, submitted) Austin MA, Hutter C, Zimmern RL, Humphries. Familial hypercholesterolemia and coronary heart disease: a HuGE association review. (HuGE review, submitted) Hutter C, Austin MA, Humphries S. Familial hypercholesterolemia, peripheral arterial disease and stroke: a HuGE mini-review. (HuGE review, submitted)

10 Technical Assistance Assisting DOH with grant preparation Diabetes Genomics Steps to a HealthierUS Further technical assistance will be provided, as needed Comprehensive Cancer Control Planning Washington State Collaborative Cardiovascular Disease Prevention State Plan

11 Training Contributed to the development of Six Weeks to Genomics Awareness Assessment and planning for training needs are in progress in collaboration with: Centers for Disease Control & Prevention Northwest Center for Public Health Practice UW Practice Coordinator

12 Center Staff and Faculty Center Staff and Faculty Director Karen Edwards, PhD Faculty Melissa Austin, PhD Kathryn Battuello, JD MPH Deborah Bowen, PhD Wylie Burke, MD PhD Barbara Burns McGrath, PhD Dave Eaton, PhD Kelly Fryer-Edwards, PhD Helen Kim, PhD Stephanie Monks, PhD Weiva Sieh, PhD Staff Tabitha Harrison, MPH Sarah Raup, MPH Candi Wines, MPH

13 DOH Collaborators DOH Collaborators Mary Frost Director, Chronic Disease Prevention & Risk Reduction Unit Washington State Department of Health Jim Krieger, MD MPH Chief of Epidemiology Planning & Evaluation Public Health Seattle & King County Karen Krueger, RN MN MBA Public Health Nurse Consultant, Chronic Disease Unit Washington State Department of Health Deb Lochner-Doyle, MS CGC State Coordinator, Genetic Services Section Washington State Department of Health Steve MacDonald, PhD MPH Epidemiologist, Office of Epidemiology Washington State Department of Health Jan Norman, RD CDE Program Manager, Diabetes Control Program Washington State Department of Health

14 Contact Us! Center for Genomics & Public Health University of Washington Box Roosevelt Way, NE Seattle, WA Phone: Fax: