: Ethidium Bromide Solution

Transcription

1 Date of issue: 08/03/2015 Revision date: 08/12/2015 Version: 2.1 SECTION 1: Identification 1.1. Identification Product form Product name. Product code : Mixtures : Ethidium Bromide Solution : R034, R041, 083E, 084E 1.2. Relevant identified uses of the substance or mixture and uses advised against 1.3. Details of the supplier of the safety data sheet Geno Technology, Inc./ G-Biosciences 9800 Page Avenue Saint Louis, United States T F technical@gbiosciences.com Emergency telephone number Emergency number SECTION 2: Hazard(s) identification 2.1. Classification of the substance or mixture Classification (GHS-US) Not classified 2.2. Label elements GHS-US labeling No labeling applicable 2.3. Other hazards 2.4. Unknown acute toxicity (GHS US) SECTION 3: Composition/information on ingredients 3.1. Substances 3.2. Mixtures : Chemtrec (USA/Canada), (Intl) Name Product identifier % Classification (GHS-US) ethidium bromide (CAS No) < 2 Acute Tox. 4 (Oral), H302 Full text of H-phrases: see section 16 SECTION 4: First aid measures 4.1. Description of first aid measures First-aid measures after inhalation First-aid measures after skin contact First-aid measures after eye contact First-aid measures after ingestion : Remove person to fresh air and keep comfortable for breathing. : Wash skin with plenty of water. : Rinse eyes with water as a precaution. : Call a poison center or a doctor if you feel unwell Most important symptoms and effects, both acute and delayed 4.3. Indication of any immediate medical attention and special treatment needed Treat symptomatically. SECTION 5: Firefighting measures 5.1. Extinguishing media suitable extinguishing media : Water spray. Dry powder. Foam. Carbon dioxide. 12/09/2015 EN (English US) Page 1

2 5.2. Special hazards arising from the substance or mixture Reactivity : The product is non-reactive under normal conditions of use, storage and transport Advice for firefighters Protection during firefighting : Do not attempt to take action without suitable protective equipment. Self-contained breathing apparatus. Complete protective clothing. SECTION 6: Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures For non-emergency personnel Emergency procedures For emergency responders Protective equipment : Ventilate spillage area. : Do not attempt to take action without suitable protective equipment. For further information refer to section 8 Exposure controls/personal protection" " Environmental precautions Avoid release to the environment Methods and material for containment and cleaning up Methods for cleaning up : Take up liquid spill into absorbent material. Other information : Dispose of materials or solid residues at an authorized site Reference to other sections For further information refer to section 8 : Exposure-controls/personal protection"". SECTION 7: Handling and storage 7.1. Precautions for safe handling Precautions for safe handling Hygiene measures : Ensure good ventilation of the work station. Wear personal protective equipment. : Do not eat, drink or smoke when using this product. Always wash hands after handling the product Conditions for safe storage, including any incompatibilities Storage conditions : Store in a well-ventilated place. Keep cool. Storage temperature : ambient temperature SECTION 8: Exposure controls/personal protection 8.1. Control parameters 8.2. Exposure controls Appropriate engineering controls Hand protection Eye protection Skin and body protection Respiratory protection Environmental exposure controls : Ensure good ventilation of the work station. : Protective gloves. : Safety glasses. : Wear suitable protective clothing. : In case of insufficient ventilation, wear suitable respiratory equipment. : Avoid release to the environment. SECTION 9: Physical and chemical properties 9.1. Information on basic physical and chemical properties Physical state Color Odor Odor threshold : Liquid : Mixture contains one or more component(s) which have the following colour(s): Dark red : There may be no odour warning properties, odour is subjective and inadequate to warn of overexposure. Mixture contains one or more component(s) which have the following odour(s): Almost odourless 12/09/2015 EN (English US) 2/5

3 ph Melting point Freezing point Boiling point Flash point Relative evaporation rate (butyl acetate=1) Flammability (solid, gas) Explosion limits Explosive properties Oxidizing properties Vapor pressure Relative density Relative vapor density at 20 C : Solubility : Water: Solubility in water of component(s) of the mixture : ethidium bromide: 5 g/100ml Log Pow Self ignition temperature Decomposition temperature Viscosity Viscosity, kinematic Viscosity, dynamic 9.2. Other information SECTION 10: Stability and reactivity Reactivity The product is non-reactive under normal conditions of use, storage and transport Chemical stability Stable under normal conditions Possibility of hazardous reactions No dangerous reactions known under normal conditions of use Conditions to avoid None under recommended storage and handling conditions (see section 7) Incompatible materials Hazardous decomposition products Hazardous decomposition products. SECTION 11: Toxicological information Information on toxicological effects Acute toxicity LD50 oral rat LC50 inhalation rat (mg/l) ATE US (oral) Skin corrosion/irritation Serious eye damage/irritation Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity 1503 mg/kg (Rat) < 0.1 mg/l/4h (Rat) mg/kg body weight 12/09/2015 EN (English US) 3/5

4 Reproductive toxicity Specific target organ toxicity (single exposure) Specific target organ toxicity (repeated exposure) Aspiration hazard SECTION 12: Ecological information Toxicity Ecology - general : The product is not considered harmful to aquatic organisms nor to cause long-term adverse effects in the environment Persistence and degradability Persistence and degradability Biodegradability in water: no data available Bioaccumulative potential Bioaccumulative potential No bioaccumulation data available Mobility in soil Other adverse effects Effect on the global warming : No known ecological damage caused by this product. SECTION 13: Disposal considerations Waste treatment methods Waste treatment methods : Waste treatment methods. SECTION 14: Transport information Department of Transportation (DOT) In accordance with DOT Transport document description : UN2810 Toxic, liquids, organic, n.o.s., 6.1, III UN-No.(DOT) : UN2810 DOT Proper Shipping Name : Toxic, liquids, organic, n.o.s. Class (DOT) : Class Poisonous materials 49 CFR Hazard labels (DOT) : Poison Packing group (DOT) : III - Minor Danger DOT Packaging Non Bulk (49 CFR 173.xxx) : 203 DOT Packaging Bulk (49 CFR 173.xxx) : 241 DOT Symbols : G - Identifies PSN requiring a technical name 12/09/2015 EN (English US) 4/5

5 DOT Special Provisions (49 CFR ) DOT Packaging Exceptions (49 CFR 173.xxx) : 153 DOT Quantity Limitations Passenger aircraft/rail (49 CFR ) DOT Quantity Limitations Cargo aircraft only (49 CFR ) DOT Vessel Stowage Location DOT Vessel Stowage Other Other information : IB3 - Authorized IBCs: Metal (31A, 31B and 31N); Rigid plastics (31H1 and 31H2); Composite (31HZ1 and 31HA2, 31HB2, 31HN2, 31HD2 and 31HH2). Additional Requirement: Only liquids with a vapor pressure less than or equal to 110 kpa at 50 C (1.1 bar at 122 F), or 130 kpa at 55 C (1.3 bar at 131 F) are authorized, except for UN2672 (also see Special Provision IP8 in Table 2 for UN2672) T (d)(2) Normal (d)(3) TP1 - The maximum degree of filling must not exceed the degree of filling determined by the following: Degree of filling = 97 / 1 + a (tr - tf) Where: tr is the maximum mean bulk temperature during transport, and tf is the temperature in degrees celsius of the liquid during filling TP28 - A portable tank having a minimum test pressure of 2.65 bar (265 kpa) may be used provided the calculated test pressure is 2.65 bar or less based on the MAWP of the hazardous material, as defined in of this subchapter, where the test pressure is 1.5 times the MAWP : 60 L : 220 L : A - The material may be stowed on deck or under deck on a cargo vessel and on a passenger vessel : 40 - Stow clear of living quarters : No supplementary information available. TDG Transport by sea Air transport SECTION 15: Regulatory information US Federal regulations Not listed on the United States TSCA (Toxic Substances Control Act) inventory International regulations CANADA EU-Regulations National regulations US State regulations SECTION 16: Other information Revision date : 08/12/2015 Full text of H-phrases:: H302 Harmful if swallowed SDS US (GHS HazCom 2012) This information is based on our current knowledge and is intended to describe the product for the purposes of health, safety and environmental requirements only. It should not therefore be construed as guaranteeing any specific property of the product 12/09/2015 EN (English US) 5/5