Professor Androulla Efstratiou

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1 Name: Professor Androulla Efstratiou Androulla Efstratiou is a Consultant Healthcare Scientist within Public Health England (formerly the Health Protection Agency) Microbiology Services Division and a Visiting Professor at Imperial College, Faculty of Medicine. Appointments also include WHO Adviser/Consultant on diphtheria and streptococcal infections, project leader for numerous national and international projects on group A and group B streptococcal infections, project leader for the European Diphtheria programmes, President of the XVIII Lancefield International Symposium on Streptococci and Streptococcal Diseases and the UK European Public Health Microbiology Programme Supervisor and Scientific Coordinator. Academic Title: Consultant Healthcare Scientist Microbiology Services Division (MSD): Colindale Public Health England 61 Colindale Avenue, London NW9 5HT, UK Tel: Fax: androulla.efstratiou@phe.gov.uk Academic Appointment: Visiting Professor, Imperial College, Faculty of Medicine, London, UK Present appointments 1998 Present Head, WHO Global Collaborating Centre for Reference and Research on Diphtheria and Streptococcal Infections, Public Health England (Formerly Health Protection Agency), Microbiology Services Division, Colindale, London, UK Head, Health Protection Agency, Streptococcus and Diphtheria Reference Unit, Respiratory and Systemic Infection Laboratory, HPA MSD, Colindale, London, UK 2010 Present European Public Health Microbiology (EUPHEM) HPA Supervisor, ECDC 1

2 2013 (April): UK Chief Scientific Coordinator for the European Public Health Microbiology Programme (European Centre for Disease Control, ECDC)) Academic Qualifications PhD in Microbiology awarded by University of London, October 1987 in collaboration with the PHLS Central Public Health Laboratory; PhD entitled 'The Pyogenic Streptococci of Lancefield Group C and Group G as Pathogens in Man' State Registered Clinical Scientist: Health Professionals Council Fellowship of the Institute of Biomedical Sciences: Specialist subject: Medical Bacteriology Current and relevant appointments held International Co-Chairperson EUPHEM Forum (ECDC): present Project Leader; ECDC programme on Coordination of a European laboratory network to strengthen laboratory diagnostics for diphtheria surveillance 2010-present Coordinator, WHO/European Laboratory Working Group on Diphtheria; 1993-present Microbiology UK Team Leader: EU FP7 Programme on European Studies on Tic Disorders in Children (EMTICs) WHO IVD Roster of Experts for Diphtheria Surveillance Scientific Secretary, International Society of Chemotherapy and Infection: Streptococcus Working Group UK Team Leader European Commission programme (EU FP7) Design of a vaccine to immunize neonates against GBS infections through a durable maternal immune response: DEVANI Consultant/Temporary Adviser to WHO on diphtheria and streptococcal infections (all WHO Regions) European Commission DG RTD Evaluator in infectious diseases 2

3 Health Technological Assessment (HTA) evaluator Specialist adviser to National Institutes of Health (Bethesda, Maryland, USA) in Streptococcal Infections Adviser/Consultant to Novartis Vaccines (group B streptococcal vaccines) Co-Chairperson, XVII Lancefield International Congress on Streptococci and Streptococcal Infections, Porto Heli, Greece, 2008 President XVIII Lancefield International Congress on Streptococci and Streptococcal Diseases, Palermo, Sicily, 2011 President International Lancefield Society, Consultant to Cyprus Ministry of Health, development of public health infrastructures ( ) Project Coordinator DIPNET; Diphtheria Surveillance Network (1 million Euros) Project Coordinator, European Commission programmes on diphtheria: : (Grants funded under the auspices of EU FP4 BioMed 2; INCO-Copernicus; INTAS; EU DGSANCO; ECDC: grant funding >2million Euros National and International Grants Reviewer: EU FP7, INCO, Wellcome, MRC, AMR, MRF, HTA National Chairperson, HPA Microbiology Services Division: Colindale, International Activities Group Member, HPA CFI Governance and Professional Affairs Committee ( ) Member HPA Group A Streptococcus Working Group Member, UK National Screening Committee Group B Streptococcus Coordinating Group Medical Adviser, Lee Spark Necrotising Fasciitis Foundation Deputy Chairperson, Health Protection Agency Group B Streptococcus Working Group

4 Currently producing strategy documents for the establishment of National Working Groups on Group A and Group B Streptococci. Current Key Grants (Project Leader/Coordinator) Coordination of a European laboratory network to strengthen laboratory diagnostics for diphtheria surveillance. ECDC present Molecular anatomy of invasive group A streptococcal isolates in England: HPA Strategic R&D fund In liaison with Imperial College, London and Sanger Centre, Cambridge Serosurvey for polio, measles, rubella, diphtheria and tetanus in Tajikistan; with WHO Regional Office for Europe and CDC Atlanta, USA: Molecular genomics and diversity of Corynebacterium diphtheriae and Corynebacterium ulcerans with Sanger Centre Cambridge European multicentre Tics in children studies (EMTICS). EU FP7 Health Programme UK Team Leader. Numerous laboratory diagnostic workshops and seminars on diphtheria held across the globe (European Region, SEARO Region, ECDC and USA, CDC Atlanta) under the auspices of EU, WHO, PATH and HPA. From 1995 to present. Commissioned by WHO SEARO to undertake laboratory training workshops and assessment of capabilities in diphtheria within Surabaya City, Indonesia (July 2011 and October 2012). Global Health Programme on Diphtheria in Indonesia ( ) PhD Supervisor and Examiner Supervisor for: T. Lamagni : Dynamics and epidemiology of group A streptococcal invasive disease in Europe (HPA) A. De Zoysa Transcontinental epidemiology of Corynebacterium diphtheriae and C.ulcerans (HPA) 4

5 A.Jasir , Group A streptococci: epidemiology and genetics of antibiotic resistance; University of Lund, Sweden; External Supervisor PhD examiner: Imperial College, University of London Medical School. (Honorary academic contract with Imperial since 2012) University of Lisbon, Faculty of Medicine, Portugal. EUPHEM Supervisor and ECDC EUPHEM Facilitator HPA/UK Microbiology Supervisor for the ECDC European Public Health Microbiology Programme (Dr K Zakikhany ; currently Amy Mikhail ). ECDC Facilitator for EUPHEM and EPIET programmes and modules Co-Chairperson EUPHEM Advisory Forum Educational Supervisor for London Medical Deanery (since 2012) Mentor for the American Society for Microbiology Mentoring program (since 2011) Major Fields of Interest Microbiology and epidemiology of diphtheria; Genomics, genetics and virulence characteristics of Corynebacterium diphtheriae; novel methods for the laboratory diagnosis of diphtheria; the use of database technology for microbiological surveillance of Gram Positive organisms; quality assurance/accreditation for Reference Laboratories; coordination of European Reference Centres on Diphtheria; public health infrastructure development in the enlarged EU. Microbiological diagnosis and epidemiology of streptococcal infections (notably Lancefield groups A, B, C and G streptococci) and pneumococcal diseases; new methodologies for the characterisation of pathogenic streptococci; molecular anatomy 5

6 of streptococci (Next-Gen sequencing technologies); the taxonomy of streptococci and other related general; sequenced based methods for speciation; virulence characteristics of streptococci; Bibliography: More than 200 publications in peer review journals and books (to be provided if needed); more than 300 abstract presentations at international conferences. Author of the WHO Manuals for Laboratory Diagnosis of Diphtheria and Control and Management (currently in press). 6