Plant Biotechnology Pipeline

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1 Corn 4 th -Generation Below- Ground Insect Protection 4 th -Generation Above- Ground Insect Protection New Modes of Action Coleopteran III 3 rd -Generation Herbicide Tolerance 4 th -Generation Herbicide Tolerance Enlist : 2,4-D & FOP New Modes of Action Lepidopteran III (Syngenta) Next-Generation CRW (Syngenta) Next-Generation Above-Ground Insect Control Traits (Syngenta) Fungal Resistance (BASF) 3 rd -Generation Above- Ground Insect Protection SmartStax PRO (Monsanto, Dow AgroSciences) Optimum Leptra Nitrogen Use Efficiency Lepidopteran/Coleopteran DP 4114 Drought Tolerance II Yield & Stress Corn II Yield & Stress Corn III DroughtGard Platform Expansion Novel Yield & Stress Traits (Syngenta) CRW = Corn Rootworm Enlist = Dow AgroSciences herbicide trait providing tolerance to 2,4-D and FOP herbicides

2 Soybean 4 th -Generation Herbicide Tolerance Roundup Ready 2 Xtend 3 rd -Generation Insect Protection 3 rd -Generation Herbicide Tolerance: Roundup Ready Xtend Crop System + 3 rd Mode of Action Hemipteran Multiple Mode Lepidopteran HPPDi + Glufosinate (Syngenta, Bayer CropScience) Nematode Resistance SCN (Syngenta) Nematode Resistance SCN (Bayer CropScience) Nematode Resistance 2 nd -Generation SCN Resistance (BASF, Monsanto) Disease Resistance ASR Disease Resistance (Syngenta) Enlist : 2,4-D + Glufosinate Enlist E3 : 2,4-D + Glyphosate + Glufosinate (Dow AgroSciences, M.S. Technologies) Balance GT/LL: Glyphosate + HPPDi + Glufosinate (Bayer CropScience, M.S.Technologies) Balance GT: Glyphosate + HPPDi (Bayer CropScience, M.S.Technologies) Cultivance: Imidazolinone (BASF, Embrapa/Brazil) Fungal Resistance (BASF) / Enlist E3 + Conkesta : 2,4-D + Glyphosate + Glufosinate + 2 Bt Traits Next-Generation Higher Yielding 2 nd -Generation Insect Protection Increased Soybean Oil & Improved Meal Value SCN = Soybean Cyst Nematode Bt = Bacillus thuringiensis ASR = Asian Soybean Rust RR = Roundup Ready LL = LibertyLink, tolerant to glufosinate herbicides HPPDi = Hydroxyphenylpyruvate deoxygenase inhibitor, family of herbicides Enlist = Dow AgroSciences herbicide trait providing tolerance to glyphosate, 2,4-D, glufosinate SDA Omega-3 Vistive Gold Low Saturated, Zero Trans-Fat Oil

3 Cotton Next-Generation Herbicide Tolerance (Bayer CropScience) Enlist 4 th -Generation Herbicide Tolerance / GlyTol TwinLink Plus: Glufosinate + Glyphosate + Expanded Insect Resistance (Bayer CropScience) 4 th -Generation Bollgard Bollgard III GlyTol = Glyphosate Tolerant, tolerant to glyphosate herbicides Enlist = Dow AgroSciences herbicide trait providing tolerance to 2,4-D and glufosinate Lygus Control Contact individual trait developers for timelines and estimated

4 Rice Dual Mode of Action Lepidopteran Protection Golden Rice 1 Beta-carotene Content (IRRI/Philippines) (BASF) Golden Rice 2 Beta-carotene Content (IRRI/Philippines) Increased Yield Hybrid Rice Technology II

5 Canola (Oilseed Rape) Dicamba Tolerance TruFlex Roundup Ready Healthy Fatty Acids (BASF, Cargill) Optimum GLY Oil Quality (Bayer CropScience) LL RR = Roundup Ready LL = LibertyLink, tolerant to glufosinate herbicides Increased Protein, Higher Nutrient Density for Feed Optimum GLY + LL LL (Monsanto, Bayer CropScience) RR + LL (Bayer CropScience) TruFlex RR DEKALB + LL (Bayer CropScience, Monsanto) ProPound Advanced Canola Meal

6 Other Crops Alfalfa Bean Eggplant Potatoes Sugarbeet 2 nd -Generation Herbicide Tolerance (Monsanto, Forage Genetics International) (Monsanto, Forage Genetics International) Reduced Lignin Virus Resistance Virus Resistance HarvXtra (Monsanto, Forage Genetics International) Geminivirus (Embrapa/Brazil) Bt Brinjal (Maharashtra Hybrid Seeds Company) Potato Virus Y (Tecnoplant/Argentina) Sugarcane / / Sunflower Wheat I II Increased Yield Yield & Stress (BASF, KWS) Insect-Protected + Roundup Ready 2 nd -Generation Herbicide Tolerance + Insect-Protected (BASF, CTC) Hybrid Wheat Technology Reduced Saturate Omega-9 Sunflower RR = Roundup Ready Bt = Bacillus thuringiensis discovery and proof of concept phases, as well as early development and have an expected launch date within the next five to seven years, subject to regulatory approvals. Contact individual trait developers for timelines and estimated

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