Quantitative Electroencephalograph and standardized Low Resolution Electromagnetic Tomography Evaluation with Neurofeedback Recommendations

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1 Nova Tech EEG, Inc 8503 E Keats Ave, Mesa, AZ web: info@novatecheeg.com telephone: Quantitative Electroencephalograph and standardized Low Resolution Electromagnetic Tomography Evaluation with Neurofeedback Recommendations Client Demographics: Patient: Redacted Birth date: 18/06/2001, Sex: M. Diagnosis: post supplement. Investigation: EEG observation. Date: 30/09/2009, Time: 18:24:59. Recording and Analysis Procedures: The electroencephalograph (EEG) was digitally recorded utilizing 19 electrodes with the International 10/20 System of electrode placement. Electrode impedances were reduced to below 5Kohms. The EEG was recorded continuously in the awake state with eyes closed and eyes open and may have included additional tasks. The EEG has been visually inspected and artifact rejected. The absolute and normalized spectral analysis has computed for each task. When age appropriate the client's data has been compared to the Institute of the Human Brain database for age ranges 6-80 years old. The output is displayed in tables and topographical maps. Output of magnitude, power, ratio and coherence have been included. ERP and ERD analysis may have been computed. Standardized Low Resolution Electromagnetic Tomography has been computed and relevant images included. This analysis and report is generated using WinEEG and LORETA-Key software. Summary of findings along with interpretation and neurofeedback recommendations have been provided by Leslie Sherlin, PhD, QEEG-D, BCIA-EEG, BCIAC. Independent Component Analysis (ICA) is an optional analysis which may be included along with advanced neurofeedback recommendations. ICA analysis is computed using the ICoN software. Summary of Findings: The quantitative EEG spectral analysis indicates mildly atypical distribution of delta with a secondary focus at electrode site P4. The posterior dominant rhythm is in the 8-10 Hz range. The theta/beta power ratio at site CZ in the eyes closed condition is 7.0. The alpha/beta power ratio in the occipital cortex is Normative database comparison analysis indicates mild elevations of delta in the parietal site, mild elevations of theta and alpha in the occipital and right parietal sites. These findings are consistent across both the eyes open and eyes closed condition, however in the eyes open condition normative database comparison analysis illustrates elevations predominantly of elevated delta diffusely across the cortex, elevations of anterior theta and occipital alpha. There were no clinically significant asymmetries noted. 1

2 The results of this analysis should be considered together with other measures in assessing, diagnosing, and treating clients. Medications can modify EEG findings and ideally the EEG should be taken under as medication free conditions as possible. It is intended only as a guide in terms of providing the most appropriate location and frequency for neurofeedback interventions. However, there are no guarantees that neurofeedback by itself is going to lead to resolution of any underlying symptoms. Neurofeedback intervention should be carefully evaluated and constantly monitored. All decisions regarding implementing suggestions are the responsibility of the practitioner. Nova Tech EEG, Inc and its affiliates assume no responsibility whatsoever for the application of any neurofeedback interventions based on the information contained in this report. With the delivery and reading of this report the referral requesting this service agrees with the terms and conditions and assumes all responsibility for any clinical intervention. Leslie Sherlin, PhD, QEEG-D, BCIA-EEG, BCIAC 2

3 The recordings were visually artifacted with noted movement and EMG artifacts removed. A fragment of EEG recorded in Eyes Closed (EC) condition is presented below. Scale: Speed - 30mm/sec, low cut frequency filter Hz, high cut frequency filter - 30 Hz 3

4 Frequency band magnitude (uv) topographies of the EC condition are presented below. Maps of EEG power spectra for bandranges Fragment: Eyes closed 18:32:51, Offset: 0.00 s, Length: s, Number of epochs Frequency band normalized power (% uv2) topographies for the EC condition are presented below. Maps of EEG power spectra for bandranges Fragment: Eyes closed 18:32:51, Offset: 0.00 s, Length: s, Number of epochs

5 2 Hz frequency band normalized power (% uv2) topographies for the EC condition are presented below. Maps of EEG power spectra for bandranges Fragment: Eyes closed 18:32:51, Offset: 0.00 s, Length: s, Number of epochs

6 The Theta/Beta power ratio topography for the EC condition is displayed below. Maps of relation of EEG power spectra Fragment: Eyes closed 18:32:51, Offset: 0.00 s, Length: s, Number of epochs V = P([Theta Hz]) / P([Beta Hz]) The Alpha/Beta power ratio for the EC condition is displayed below. Maps of relation of EEG power spectra Fragment: Eyes closed 18:32:51, Offset: 0.00 s, Length: s, Number of epochs V = P([Alpha Hz]) / P([Beta Hz]+[Beta Hz]) 6

7 The results of normative comparisons in the EC condition are displayed below. Name: Redacted-Grand Average File Date of observation: 01/10/2009 Total epoch number: 1, 20 Comparison power spectra (uv^2) 7

8 Comparison of normalized power spectra (%), Normalization frequency band Hz 8

9 Comparison of asymmetry of power spectra (%) 9

10 The results of normative comparisons of coherence values in the EC condition are displayed below. The first set of images is of left to right electrode pairs, the second set of images is of the anterior to posterior electrode pairs and the third set of images is of homologous electrode pairs. Diagram of EEG coherence Fragment: Eyes closed 18:32:51, Offset: 0.00 s, Length: s, Number of epochs

11 Eyes Open The recordings were visually artifacted with noted movement and EMG artifacts removed. A fragment of EEG recorded in Eyes Open (EO) condition is presented below. 11

12 Frequency band magnitude (uv) topographies of the EO condition are presented below. Maps of EEG power spectra for bandranges Fragment: Eyes opened 18:40:43, Offset: 0.00 s, Length: s, Number of epochs Frequency band normalized power (% uv2) topographies for the EO condition are presented below. Maps of EEG power spectra for bandranges Fragment: Eyes opened 18:40:43, Offset: 0.00 s, Length: s, Number of epochs

13 2 Hz frequency band normalized power (% uv2) topographies for the EO condition are presented below. Maps of EEG power spectra for bandranges Fragment: Eyes opened 18:40:43, Offset: 0.00 s, Length: s, Number of epochs

14 The Theta/Beta power ratio topography for the EO condition is displayed below. Maps of relation of EEG power spectra Fragment: Eyes opened 18:40:43, Offset: 0.00 s, Length: s, Number of epochs V = P([Theta Hz]) / P([Beta Hz]) The Alpha/Beta power ratio for the EO condition is displayed below. Maps of relation of EEG power spectra Fragment: Eyes opened 18:40:43, Offset: 0.00 s, Length: s, Number of epochs V = P([Alpha Hz]) / P([Beta Hz]+[Beta Hz]) 14

15 The results of normative comparisons in the EO condition are displayed below. Name: Redacted-Grand Average File Date of observation: 01/10/2009 Total epoch number: 1, 23 Comparison power spectra (uv^2) 15

16 Comparison of normalized power spectra (%), Normalization frequency band Hz 16

17 Comparison of asymmetry of power spectra (%) 17

18 The results of normative comparisons of coherence values in the EO condition are displayed below. The first set of images is of left to right electrode pairs, the second set of images is of the anterior to posterior electrode pairs and the third set of images is of homologous electrode pairs. Diagram of EEG coherence Fragment: Eyes opened 18:40:43, Offset: 0.00 s, Length: s, Number of epochs

19 Images of neuronal electric activity computed with s LORETA. The images display the neuronal generators of the EEG during condition. Three orthogonal brain views in Talairach space are shown, sliced through the region of the maximum activity. Structural anatomy is shown in black outline. Left slice: axial, seen from above, nose up; center slice: saggital, seen from the left; right slice: coronal, seen from the rear. Talairach coordinates: X from left (L) to right (R); Y from posterior (P) to anterior (A); Z from inferior to superior. The location of maximum activity is given as (X,Y,Z) coordinates in Talairach space, and is graphically indicated by black triangles on the coordinate axes. For further explanation regarding sloreta you may consult (1.) Pascual-Marqui RD. Standardized low resolution electromagnetic tomography: technical details. Methods and Findings. Experimental and Clinical Pharmocology. 2002, 24D:5-12. Eyes Open Theta 19

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