Czech Biotech. Great past, present, promising future Overall description Association CzechBio CzechBio members
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2 Czech Biotech Great past, present, promising future Overall description Association CzechBio CzechBio members
3 Great past Czechoslovakia used to be extremely strong in traditional biotech Biotransformations: Crop and animal breeding Fermentation industry Famous brewery tradion Production of wine, ethanol, baker s yeast Aminoacid production, cyclosporine A, ergot alcaloids, vitamins, food additives Among pioneers of antibiotics production penicillin (October 1949) World famous school of continuous culture technology (at Institute of Microbiology of Czech Academy of Science)
4 Current shape of biotech in CZ Somewhat behind in cutting-edge biological research Limited cooperation between academia and private companies Limited interest of the venture capital Advance biotech intellectual property is limited So far Czech biotech companies didn t succeed in delivering original biotech product in field of human medicine to the market
5 Biotech industry in CZ All together more than 40 companies located mostly in the region of Central Bohemia and South Moravia Directly employed: employees Total yearly turnover: mil EUR Average year growth: % 30% 9% 38% Výroba Služby 23% Výzkum a vývoj Ostatní
6 Promising future Government starts to recognize the problem: Advanced biotechnology and molecular biology among strategic long-term research orientations More funds to competent teams and individuals Good culture, education, enough PhDs, qualified manpower National applied research support scheme Incentives for Academia collaboration with industry ERDF funds (4,5 bil. Euro ), for OP R&D fair portion going into biotech Number of projects BIOCEV, CEITEC, NBBC, CzechBio
7 Promising future 2001 : Center of Biological Technologies technological incubator incl. green tech in South Bohemia 2006: Water Treatment Alliance - development high tech tools and innovations (incl. biotech) in water treatment 2007: CEITEC Central European Institute of Technology (South Moravia) BIOCEV Biotech & Biomed Research Center of AS CR promotion of cutting edge biotech and biomed R&D in CZ, 2008 (January) Institute of Biotechnology established by AS CR 2008 (December) CzechBio association established
8 CzechBio z. s. p. o. A rapidly growing association of biotech companies, renowned research institutions and Universities operating in CZ Aiming at developing Czech biotech industry Represents the famous traditional Czech biotech R&D Founding members: Current members: 20 private biotech companies 29private biotech companies 3 R&D institutions + 1 university
9 CzechBio membership base Eco/Envir Pharm/Med Prod Diag/Assay Prod Diag/Testing Serv Mol Biol Other 9 R&D Services Production Other
10 Selected biotech companies - Prague Immunotech (Beckman Coulter) immunodiagnostics BIOPREPARÁTY biological plant protection GeneAge Technologies expression profiling Genomac International sequencing/genotyping LentiKat waste water treatment R&D Top-Bio molecular biol. kits producer SME (<5)
11 Sel. biotech companies Central Bohemia Apronex SME, recombinant proteins (4 p) Baxter Czech flu vaccine production site Biologicals SME, forensics, HCV-Y-Screen Dyntec veterinary products EXBIO Mab and reagent producer Lonza Biotec fermentation plant and R&D FDA-registered pharma enzymes Proteix SME, recombinant proteins (3 p) recoli SME, recombinant proteins VIDIA SME, clinical diagnostic kits BioTest drug and biologicals testing,r&d
12 Sel. biotech companies South Moravia BioVendor SME, recombinant proteins, diagnostics Bioveta veterinary vaccines R&D and production Enantis SME, recombinant dehalogenases contract research in protein engineering EPS SME, bioremediation, biogas Moravian-Biotechnology SME, custom antibody services TEST-LINE SME, human and veterinary diagnostics
13 Sel. biotech companies remaining regions GENERI BIOTECH SME, oligonucleotides, DNA genotyping services Contipro Group world leader in hyaluronic acid GMP recombinant defensins, wound healing R&D Protean SME, DNA diagnostics, recombinant proteins ENVISAN-GEM bioremediation GEN-TREND SME, diagnostics and proteins AgroBio agrochemicals and agrobiologicals Biocel pulp industry fodder yeast producer IVAX-Teva Pharmaceuticals, generics Ascoprot Biotech SME (5 p.) rec. proteins OlChemIm SME, phytohormones, antibodies (5 p)
14 Basic facts about largest member companies BTÚ AV ČR, v.v.i employees founded project BIOCEV LONZA Biotec, s.r.o, Kouřim Employees: 380 Bulk custom GMP biomanufacturing Sevapharma a.s. Employees 100 vaccines, imunomodulators, alergens Ann. Turnover : CZK1,5 bilion EUR 60 milion Turnover: CZK150 milion EUR 6,5 milion Biopharm a.s. Employees: 90 Veterinary vaccines and drugs Turnover: CZK 80 milion EUR 3,3 milion BioVendor Laboratorní medicína a.s. Employees: 150 Recombinant proteins and ELISA kits Turnover: CZK 1 bilion EUR 40 milion Bioveta a.s. Employees: 330 Turnover: CZK 500 milion EUR 20 milion Veterinary vaccines and immunopreparations
15 CzechBio offers: Guidance through the Czech biotech sector Partnership with academic institutions and biotech companies offering wide range of biotech services Comprehensive database of biotech companies to be approached Partnership in R&D activities Representation in number of expos & trade fairs Active participation on regular expert seminars and mingling sessions Use of our laboratory
16 Contact: Web: Address: Nad Safinou II/366, Jesenice u Prahy Tel: Contact person: Marek Polach marek.polach@czechbio.org
17 Thank you for your attention!
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Uses of 2D gel electrophoresis in recombinant protein production Kendrick Laboratories, Inc www.kendricklabs.com Recombinant proteins are biologics What is a Biologic? Biological products are those derived
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This page intentionally left blank Biotechnology Fifth edition Biotechnology is the major technology of the twenty-first century yet few people realise how much it impacts on many aspects of human society.