Human Experimental Laboratory

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1 Human Experimental Laboratory Sahlgrenska academy Department of neuroscience and physiology Section of psychiatry and neurochemistry Addiction Biology Unit Anna Söderpalm Gordh, Docent/Associate Professor

2 The laboratory environment: -a sofa with pillows -chairs -a table -lamps -magazines -boardgames -a TV -bookshelf -a rug -curtains in window

3 Alcohol challenges: Acute doses Consumption

4 Social conditions: Social drinking Isolated drinking

5 Subjective mood test: Biphasic Alcohol Effect Sale (BAES) Addiction Research Center Inventory (ARCI) Visual Analague Scale (VAS) Profil Of Mood Scale (POMS) Drug Effects Questionnaire (DEQ)

6 Objective measures: Blood pressure Alcometer Voice Film Motor activity

7 Variables Family history of alcoholism Gender differences Age differences Stress

8 Current collaborations -Alcohol and episodic memory -Alcohol intoxicated eye witnesses to intimate partner violence tillsammans med Claudia Fahlke and Per Anders Granhag, Göteborg University. -Longitudinal Epidemiological Intervention Study of Alcohol Drinking and Stress in Young Adults tillsammans med Mats Berglund och Claes Andersson, Malmö Högskola. -Gen-miljöinteraktion: Studier av psykosociala riskfaktorer, alkohol och monoaminerga mekanismer tillsammans med Lars Oreland och Kent Nilsson, Uppsala Universitet -The Biphasic Alcohol Effects in humans: an fmri study tillsammans med Associate Professor Tara White och Professor Robert Swift, Center for Alcohol and Addiction Studies, Brown University -Voice recorded stimulant-like effects of alcohol promotes drinking behaviour in humans tillsammans med Anders Erikson och Dr. Åsa Abelin vid Lingvistiska institutionen

9 My articles connected to the subjective effects of drugs in humans Hagsand, A., Roos af Hjelmsäter, E., Granhag, P.A., Fahlke, C., & Söderpalm- Gordh, A. (2012). Do perform sober alcohol eyewitnesses better than intoxicated in a lineup? The European Journal of Psychology Applied to Legal Context, 2013, 5(1): Hagsand, A., Roos af Hjelmsäter, E., Granhag, P.A., Fahlke, C., & Söderpalm- Gordh, A. (2012). Bottled memories. On how alcohol affects eyewitness recall. Scandinavian journal of psychology, accepted Söderpalm Gordh AHV, Brkic S, Söderpalm B (2011) Stress increases consumption of alcohol in humans with a Type 1 Family History of alcoholism in an experimental laboratory setting Pharmacology Biochemistry and Behavior, 99: Söderpalm Gordh, AHV, Söderpalm B (2011) Healthy subjects with a family history of alcoholism show increased stimulative subjective effects of alcohol. Alcoholism: Clinical and Experimental Research, 35: Andersson, C., Söderpalm Gordh, A.H.V., Berglund, M (2007) Use of real-time interactive voice response (IVR) in a study of stress and alcohol consumption. Alcoholism: Clinical and Experimental Research 31: Söderpalm, A.H.V., Lindsey, S., Purdy, R.H., Hauger, R., de Wit, H (2004) Administration of progesterone produces sedative-like effects in men and women. Psychoneuroendocrinology 29: de Wit, H., Söderpalm, A.H.V., Nikolayev, L., Young, E. (2003) Acute stress increases alcohol consumption in social drinkers. Alcoholism: Clinical and Experimental Research: 48(8) Söderpalm, A.H.V., Nikolayev, L., de Wit, H (2003) Acute stress suppresses subjective responses to methamphetamine in humans. Psychopharmacology: 170(2) Söderpalm, A.H.V. & de Wit, H (2002) Effects of stress and alcohol on subjective state in humans. Alcoholism: Clinical and Experimental Research. 26 (6): Söderpalm, A.H.V., Schuster, A., & de Wit, H. (2001) Antiemetic efficacy of smoked marijuana: subjective effects on nausea induced by syrup of ipecac. Pharmacology Biochemistry and Behavior, 69: Submitted and soon to be submitted Söderpalm Gordh and Söderpalm B, Stress and the Subjective effects of Alcohol in Humans with a Type 1 Family History of Alcoholism Söderpalm Gordh and Söderpalm B, Alcohol consumption in healthy subjects with a Type 1 family history of alcoholism. Malin Hildebrand Karlén, Emma Roos af Hjelmsäter, Claudia Fahlke, Pär Anders Granhag and Anna Söderpalm-Gordh.. Alcohol intoxicated eye witnesses to intimate partner violence Linda Zachringe, Bo Söderpalm, Anna Söderpalm Gordh. Social versus isolated alcohol drinking in humans: a placebo controlled study Sejla Brkic, Bo Söderpalm, Anna Söderpalm Gordh. Stress and the subjective response to alcohol: a dose response study Sejla Brkic, Bo Söderpalm, Anna Söderpalm Gordh. Does age effect the responses to alcohol?

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