Breast Cancer. Progress and Controversies. Hotel Royal Continental Via Partenope, 38 Napoli

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1 Breast Cancer Progress and June, Hotel Royal Continental Via Partenope, 38 Napoli

2 Introduction Presidents Giuseppe D'Aiuto Michele De Laurentiis Sabino De Placido Paolo Muto Honorary President Angelo Raffaele Bianco reast Cancer, the most frequent malignancy among women, is a complex and heterogeneous disease. During the last decades, knowledge development in the field has Bbeen astonishing and it has been driving a continuous progress in the clinical management of the disease. If on one hand the pace of such a progress is exciting, on the other hand, its rapidity forces oncologists to a constant debate in the attempt to address the many controversial issues that meanwhile arise. In this dynamic scenario, the first Breast Cancer: Progress and conference, aims at offering at the best Italian and international multidisciplinary experts in the field an opportunity to exchange opinions about major breast cancer topics, to create collaboration on new ideas and projects, to encourage breast cancer teams integration. At the same time, this will put the attendants in a position to receive a high scientific level overview of the state-of-the-art of breast cancer treatment and to deeply perceive the on-going debate on controversial matters. We are confident that you will appreciate this opportunity and we aim at periodically repeating this scientific initiative in the future. Università degli Studi di Napoli Federico II ISTITUTO NAZIONALE TUMORI IRCCS - Fondazione Pascale

3 09:15-09:45 Welcome and Opening Ceremony Chairs: Giuseppe D'Aiuto, Michele De Laurentiis, Sabino De Placido Authorities: Gennaro Ciliberto, Tonino Pedicini, Michele Schiano 09:45-11:00 Risk Factors and Prevention Chairs: Alberto Costa and Franco Salvatore, Italy Lecture: Obesity, insulin resistance and chemoprevention strategies. Annamaria Colao, Italy Endocrine Chemoprevention: ready for prime time? Paolo Marchetti Vitamins and natural compounds: mirage or reality? Andrea De Censi BRCA1 and BRCA2 mutations through Next Generation Sequencing (NGS). Valeria D'Argenio FRIDAY June 14 A. Colao, A. Costa, V. D Argenio, A. De Censi, P. Marchetti 11:00-11:15 Coffee Break 11:15-12:30 Detection and Imaging Chairs: Antonella Petrillo and Alfredo Siani Lecture: New technology and Future prospects for Breast Imaging. Antonella Petrillo Surveillance of High Risk Population Adriana Bonifacino Advances in Magnetic Resonance Imaging Roberta Fusco Nuclear Medicine: progress and controversies in Breast Cancer? Secondo Lastoria A. Bonifacino, R. Fusco, S. Lastoria, A. Petrillo, A. Siani 12:30-14:15 Lunch Break

4 FRIDAY June 14 14:15-15:30 NeoAdjuvant Therapy Chairs: Fortunato Ciardiello and Pierfranco Conte Lecture: Neoadjuvant treatment: The story so far. Gunther Von Minckwitz Endocrine Neoadjuvant Therapy Marco Angelo Colleoni Making the patient a living laboratory Giuseppe Frasci Predicting Outcome by Functional Genomics Valentina Guarneri F. Ciardiello, M.A. Colleoni, P. Conte, G. Frasci, V. Guarneri, G. Von Minkwitz 15:30-16:45 Adjuvant Therapy Chairs: Michele De Laurentiis and Sabino De Placido Lecture: From clinical trials results to personalized treatment. Paolo Pronzato Chemotherapy benefit in Luminal breast cancer Carmen Criscitiello Bone anti-resorptive agents in the adjuvant setting Fabio Puglisi Adjuvant Therapy of TNBC Giorgio Mustacchi C. Criscitiello, M. De Laurentiis, S. De Placido, G. Mustacchi, P. Pronzato, F. Puglisi 16:45-17:00 Coffee Break

5 17:00-18:15 Treatment of Endocrine-non-responsive Metastatic Disease Chairs: Sandro Barni and Francesco Cognetti Lecture: Targeting molecular pathways in Endocrine-non Responsive MBC. Pierfranco Conte Chemotherapy: How long is long enough? Alessandra Gennari Metronomic Chemotherapy: is there any supporting evidence? Saverio Cinieri TNBC: which chemotherapy? Which Targets? Giuseppe Curigliano Nab-paclitaxel and Eribulin: is it real progress? Alessandra Fabi FRIDAY June 14 F. Barni, F. Cinieri, F. Cognetti, P. Conte, G. Curigliano, A. Fabi, A. Gennari

6 SATURDAY June 15 09:15-10:30 Treatment of Endocrine-Responsive Metastatic Disease Chairs: Fortunato Ciardiello and Michele De Laurentiis Breast Unit Network Award Lecture: Endocrine therapies and targeted drugs: looking for the perfect match. Carlos Arteaga Estrogen Receptor Downregulators: their place in the current landscape Giuseppe Naso Targeting m-tor pathway Romano Danesi Treatment of HER2+/ER+ tumours Grazia Arpino G. Arpino, C. Arteaga, F. Ciardiello, R. Danesi, M. De Laurentiis, G. Naso 10:30-11:45 Perspectives in Management of Breast Cancer Chairs: Paolo Muto and Franco Perrone Lecture: Gene Signatures in the current management of Breast cancer. Fabrice Andrè Intraoperative and accelerated radiation therapy Roberto Orecchia New versus old Bone anti-resorptive treatments Francesco Nuzzo ECT: present evidence and future perspectives Riccardo Bussone Cardiac Toxicicity of Targeted Agents: need for Guidelines? Nicola Maurea F. Andrè, R. Bussone, N. Maurea, P. Muto, F. Nuzzo, R. Orecchia, F. Perrone

7 11:45-13:00 Breast Cancer in Young Patients Chairs: Giuseppe D'Aiuto and Nando Riccardi Lecture: Epidemiology of breast cancer in 'under-forty' women. Prisco Piscitelli Breast Cancer in young women: Clinical Management Massimiliano D'Aiuto Fertility Preservation in Breast Cancer pts Lucia Del Mastro Pregnancy in Breast Cancer Survivors Francesca Di Rella SATURDAY June 15 G. D'Aiuto, M. D Aiuto, M. Del Mastro, P. Piscitelli, F. Di Rella, N. Riccardi

8 Breast Cancer Progress and Segreteria Scientifica Massimiliano D'Aiuto, Francesca Di Rella, Adriano Gravina, Giovanni Iodice, Vincenzo Labonia, Gabriella Landi, Francesco Nuzzo, Carmen Pacilio, Roberta Caputo, Daniela Cianniello Institutional Project Managers Mirella Esposito, Michela Piezzo INFORMAZIONI GENERALI L Evento è stato accreditato presso il Ministero della Salute dal Provider Andromeda Srl N. 163 con N. 7 crediti ECM per i primi 270 iscritti appartenenti alle seguenti figure professionali: Medico Chirurgo (specialista in chirurgia generale, radiodiagnostica, ginecologia, cardiologia, oncologia) Farmacista Ospedaliero Biologo Tecnico Sanitario Biomedico Infermiere I crediti ECM verranno attribuiti a coloro che parteciperanno all'intera durata dell evento e che risponderanno esattamente al 75% del questionario ECM. segreteria organizzativa In copertina: Fabrizio Scala, Maschio napoletano con profilo di donna All rights reserved Galleria Vanvitelli NAPOLI Tel Fax

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