Study Guide 2009/2010

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1 PDEng Programme BioProduct Design Study Guide 2009/2010 Faculty of Applied Sciences

2 Disclaimer Every effort has been made by the faculty in putting together this guide. However, further details about a number of subjects will only be available after the guide has been printed. For that reason, the information published by the faculty in this handbook is subject to change. Amendments, further details, and a more extensive description of the subjects can be found on Blackboard: and in the digital study guide BioProduct Design

3 Personal Data name address postal code/city or town date of birth home phone work phone mobile work fax student number giro account no. passport no. driving licence bank account no. valid through valid through social-fiscal no. family doctor medications allergic to medications blood type RH factor donor card: yes/no IN EMERGENCIES PLEASE CONTACT name address postal code/city or town home phone mobile If found, please return this student guide or contact the owner. Study Guide 2009/2010

4 Preface Dear Designer, Welcome to the Faculty of Applied Sciences at Delft University of Technology, and a special welcome to the PDEng-programme in BioProduct Design. The programme recently started, in September 2007, and it is the first to combine Life Sciences and Technology with Design Methodology. Through this innovative combination of different fields you learn to design new products for the Food, Pharma and Fine Chemicals industry. Your course programme is to a certain extent tailor-made, which means that when choosing your profile you have the freedom to select courses depending on your interest and objectives. Please use this Handbook and the different websites to deliberately draw up your programme. Furthermore, you will find details about the programme, research groups, faculty members, practicalities and other useful information. During the year, two other important source of information are the university Blackboard site (blackboard.tudelft.nl) and the Electronic Studyguide (studyguide.tudelft.nl), which provide you with the most up-to-date information on courses offered by Delft University of Technology. The latest news about the university can be found on If anything is unclear or if you have other questions, do not hesitate to ask the Course Coordination Team, another faculty member or an advanced Designer. I m looking forward to your contribution in BioProduct Design and I wish you an interesting, fruitful and enjoyable time in Delft. Prof. Dr. Han de Winde Programme Director BioProduct Design

5 Contents Personal Data 3 Preface 4 1 University Profile Education & Student Affairs Service Desk BLACKBOARD - Virtual learning environment The TU Delft Library Self-study spaces Student & Career Support Facilities for handicapped students Sports & Cultural Centre Student ombudsman Health & Safety, University Emergency Services Accommodation Medical Care MoTiv Public Lecture Series Delta 19 2 Information about the PDEng-praogramme in BioProduct Design People responsible for the programme/important addresses Research Groups in the Department of Biotechnology Faculty Building Addresses (see map) Courses: Registration and Grading The building Other Important Information Useful (web) Addresses 33 Study Guide 2009/2010

6 3 Designer Programme Programme structure of BioProduct Design First year Second year Timetables 40 4 Course descriptons 41 5 Map of TU Delft Campus Year planner Lecture hours 122 7Diary 123 BioProduct Design

7 1. University Profile

8 University Profile TU Delft aims to be a preferred partner in education for students worldwide by offering intrinsically challenging and didactically inspiring courses. Intrinsically challenging because of the direct connection with urgent societal themes, particularly in the area of sustainability. Didactically inspiring through the use of active educational methods to give our students own creativity as much freedom as possible. TU Delft sees its students as its future alumni, alumni who can be flexibly deployed and can take up a prominent position on the international labour market. The programme leading to the qualification of Delft engineer is an A-brand worldwide. To maintain this quality guarantee, TU Delft is constantly developing its curriculum, both intrinsically and didactically. The university also collaborates closely with national and international universities, research institutes and partners in industry. These ties are a means for our students to gain valuable and relevant knowledge and experience, providing them with the building blocks for a successful future career. TU Delft (Delft University of Technology) Visitor address Mekelweg CC Delft Postal address Postbus AA Delft Tel.: +31 (0) (switchboard) Fax: +31 (0) info@tudelft.nl (enquiries) Web site: BioProduct Design

9 University Profile 1.1 Education & Student Affairs The Education & Student Affairs department provides educational activity support: administration, student guidance, support for foreign students, sports, culture and international projects. Jaffalaan 9A (visitor entrance on Mekelweg) 2628 BX Delft Tel.: +31 (0) Fax: +31 (0) Web site: Service Desk Every faculty has a service desk. This is the contact point for students (and staff) for all questions concerning educational and student affairs, ICT and facility services, such as: Prospectuses Transcripts Turning in mark sheets Certificates for students (such as for completion of programme components, marks or study credits for purposes of switching to another programme or credit-related/achievement-related grant) Degree audit application Questions on the TAS examination registration system. More information, including opening times, can be found on The Servicedesk of the faculty of Applied Sciences is located in the TN- Building, Lorentzweg 1. Study Guide 2009/2010

10 University Profile 1.3 BLACKBOARD - Virtual learning environment Blackboard is TU Delft s virtual learning environment. All TU Delft students registered in the student enrolment system ISIS, all teaching staff and other personnel registered in Peoplesoft, as well as alumni, have access to Blackboard and can make use of the virtual learning environment. Almost all communication between students, instructors and staff goes through Blackboard. After logging in, you will find the relevant information on studying and working at TU Delft. Tel.:+31 (0) Web site: Support: The TU Delft Library Your virtual reference desk! All relevant technical and scientific information The TU Delft Library is the largest technical and scientific library in the Netherlands. The library selects, administers, processes and supplies information relevant to your study collected from the Netherlands and abroad. Much of this information is in electronic form. All the relevant science and technology information you need The TU Delft Library is the largest technical and scientific library in the Netherlands. The library selects, administers, processes and supplies information relevant to your studies from in and outside the Netherlands. Much of the information is digital. Stop searching, start finding! During your course, you will find that the Virtual Knowledge Centre (VKC) of your programme will come in very useful. The VKC is the ideal place to start when looking for information in your field, as it provides virtually all knowledge in your field. Learn about your VKC at BioProduct Design

11 University Profile The digital window At you will find not just information on specific subjects, but also practical information about the Library, the online catalogue, databases, works of reference, internet sources, instructions and maps. There are also articles, PhD theses, reports, graduation dissertations, lecture notes, patents and other TU Delft publications at If you are looking for specific information, or if you have a question, request, complaint or comment about the services provided by the Library, go to the digital window of the Library. For maps, go to Get your questions answered immediately You can communicate with the Library Customer Services via Ask Your Library at a time, place and manner of your own choosing. Many of your questions will be answered immediately. During office hours you can chat to a Library employee, who can also browse along with you. The employee is then able to help you find specific sources by pointing out information with the cursor. The answers to some questions can be found in the Frequently Asked Questions, but you can also telephone us (+31 (0) ), mail us (library@tudelft.nl), or visit one of our branches. You can find them on Easy If you use a computer that is connected to the TU Delft campus network, you can use, digitally, virtually every service provided by the Library. The Central Branch on Prometheusplein 1, behind the Aula Congress Centre, is open during the daytime, evening, and at weekends, for browsing through the books, studying with or without a computer, meeting, and making copies. The opening times of the Library are extended yet further during examination periods. The Central Branch is also where you will find the Trésor, the treasure house with unique, fragile and valuable items. The Trésor can be visited by appointment ( Central Library Prometheusplein ZC Delft Tel.: +31 (0) library@tudelft.nl 1 Study Guide 2009/2010

12 University Profile 1.5 Self-study spaces Specially set up self-study spaces are available to you in the faculties and library for independent study. You will find these self-study spaces in separate spaces and in the foyers of the buildings. Many self-study spaces are equipped with laptop connections. 1.6 Student & Career Support Student & Career Support is there to help you when you encounter issues that impede good studying. Both individuals and groups can consult Student & Career Support for support and advice. Consult the student counsellors, student psychologists and/or the information centre for assistance with: legal issues, scholarships/grants and financial support, psychosocial support, help with studies and career orientation on the labour market. At the desk in the Education & Student Affairs building at Jaffalaan 9a (Mekelweg entrance), you can make an appointment with a student counsellor or student psychologist, or obtain more information about the information centre. The student psychologists also have an open consultation hour on Tuesday and Thursday mornings from , during which you can see a student psychologist without an appointment. Please report to the desk when you come to attend the open consultation. Additionally, Student & Career Support will also appreciate a phone call or to let the office know that you are coming. At Student & Career Support you can also attend workshops and trainings such as Constructive Thinking, Relaxing, Mind Mapping, Applications, Studying with Dyslexia, and Personal Effectiveness. For more information, see On the ground floor at the Education & Student Affairs desk, you will also find the Information Centre (open from 9.00 to 17.00), where you can go for information about your academic or future professional career. The Information Centre can provide information on subjects such as university and higher professional education programmes, study and career choices, studies abroad, exchange programmes, summer courses, financial aid/ 1 BioProduct Design

13 University Profile grants and language courses. Most of the day, the desk will be staffed with someone to help you. Opening hours: Monday through Friday from 9.00 to Jaffalaan 9A (visitors entrance on Mekelweg) BX Delft Tel.: +31 (0) Web site: Facilities for handicapped students The university will ensure that the education is also accessible to students with a disability. This means that there must be appropriate facilities for disabled students or students with a chronic illness, whether financially or by providing special educational facilities. If you have special needs, contact your academic counsellor. Please give notice of any needs you may have as early as possible, as some facilities may take some time to organise. 1.8 Sports & Cultural Centre The Sports & Cultural Centre offers nearly every kind of indoor and outdoor sport. Most fields and pitches are lit for evening play. You can also take part in a variety of cultural activities: Courses, including videography, photography, painting, drawing, sculpting, ceramics, instrument building, classical music, light & popular music, computer-assisted sound processing, modern and oriental dance, capoeira, philosophy and writing. Vocal and instrumental musical groups. Use of musical instruments, including pianos, drum sets, saxophones and guitars. TU Delft Sports Centre Mekelweg CD Delft Tel.: +31 (0) sportcentrum@tudelft.nl Web site: 1 Study Guide 2009/2010

14 University Profile TU Delft Cultural Centre Mekelweg CD Delft Tel: +31 (0) Web site: Student ombudsman If you, as a student, have a complaint about TU Delft, the faculty or staff, you should first try to resolve the situation with your faculty s academic counsellor. If that doesn t work, visit the student ombudsman. The student ombudsman can help you to solve problems and make proposals aimed at preventing others from encountering similar circumstances. The ombudsman for TU Delft is W.J.M. Knippenberg. Aula TU Delft Mekelweg CC Delft Tel.: +31 (0) ombudsman@tudelft.nl Contact the ombudsman by first Health & Safety, University Emergency Services Like the staff of TU Delft, students are entitled to a safe and healthy workplace/study space. This also entails the obligation to act in the interests of your own safety and that of others. The Netherlands has working conditions legislation ( ARBO legislation ) in place governing safety standards and rules of conduct. TU Delft also has specific environmental, health & safety rules. Basic rules Students may not enter technical areas. Performance of actions and experiments involving an element of risk are only permitted on the instruction of and with permission of the supervisor. Anyone who suspects that he or she may be exposed to risk in the performance of an assignment may refuse 1 BioProduct Design

15 University Profile that assignment and contact the Health & Safety Adviser concerning the matter. Undesirable behaviour Aggression, sexual intimidation, threats, pestering and discrimination are considered undesirable behaviour and are not tolerated. Undesirable behaviour can be reported to the Executive Board. You can also contact your faculty s confidential advisor, who can handle complaints discretely. Smoking prohibited TU Delft is a non-smoking institution. Smoking is not permitted anywhere except in the smoking areas and locations where smoking is temporarily permitted. Violation of the non-smoking rule is considered undesirable behaviour. Anyone who is being disturbed by smoking can report it to the Health & Safety Adviser or the confidential adviser. Computer work Intensive computer work can lead to neck and upper body problems. These conditions are commonly referred to as RSI. The chance of RSI is increased when working under pressure, in situations such as completing a thesis. Advanced RSI is very difficult to cure and should be avoided at all costs. Make sure your working posture is always correct and take short work breaks at regular intervals. One useful tool to help you do this is the Workpace programme. The Health & Safety Adviser can help you and evaluate your workspace. Emergencies and University Emergency Services TU Delft has a University Emergency Services organisation. The members of the University Emergency Services organisation are known to the staff. They perform first aid and act in the event of an emergency Any time you are injured, always seek treatment. Always report any accidents or nearaccidents to University Emergency Services. In the event of fire, a work-related accident or a dangerous situation, follow these rules: A slow whoop siren over the public address system indicates that an alarm has been sounded. Follow the instructions immediately. Get yourself to safety and warn others. In the event of fire, activate a fire alarm. In the event of an emergency, dial the emergency number (112) on a land line and answer the questions. 1 Study Guide 2009/2010

16 University Profile Follow the instructions of University Emergency Services personnel. For more information, see and follow the links to Staff, A-Z index Accommodation In principle, you have to arrange your own accommodation. The consent system is fairly widely in effect in Delft student residences. This means that you will have to interview with the residents of the house. Finding housing in Delft is difficult, and finding cheap housing is even harder, so start looking as early as possible! DUWO TU Delft has a contract with accommodation organisation DUWO for the housing of foreign students and guests. The contracts with the students/ guests or foreign students are fixed-term contracts with the option of extension. Applications for housing will be granted on a first come first served basis. Visitors address Stichting DUWO Kanaalweg EB Delft Postal address Postbus AB Delft Tel.: +31 (0) info@duwo.nl Web site: Medical Care The student healthcare organisation Stichting Studentengezondheidszorg (SGZ) provides both medical and psychotherapeutic healthcare for students. Because the SGZ principally provides preventative help, we recommend you have your own GP who can visit you if you are ill. This can be one of the SGZ s own GPs. 1 BioProduct Design

17 University Profile SGZ Beukenlaan 4G 2612 VC Delft Web site: General Practitioners: To make an appointment, call : +31(0) , Monday to Friday 8:30-12:30 hrs and 13:30-16:30 hrs. (Closed Friday afternoon) studentenartsen@sgz.nl Vaccinations: Tel.: +31 (0) vaccinatie@sgz.nl Psychologists: Tel.: +31 (0) psychologie@sgz.nl MoTiv MoTiv is a church organisation at TU Delft. Its aim is to engender motivation, inspiration and passion in those who choose a profession in technology. Participants in the MoTiv programmes explore their inner strength and commitment. MoTiv s activities are designed to augment personal skills and social support and to make a contribution to the technical/cultural debate in society. MoTiv has pastors with whom you can make an appointment for individual pastoral coaching. For those seeking reflection, there is an Ecumenical church service every Sunday at at Noordeinde 4. Voorstraat JS Delft Tel.: +31 (0) info@motiv.tudelft.nl Web site: 1 Study Guide 2009/2010

18 University Profile 1.14 Public Lecture Series Studium Generale, the TU Delft Public Lecture Series, helps you stay on top of the oldest and newest developments in science, art, culture and society. Studium Generale offers you the opportunity to expand your horizons and learn about disciplines other than your own area of study. Twice per year, Studium Generale issues its programme listings announcing all activities. The programme listings are distributed in all TU buildings and can also be obtained individually. To be sure you are always informed of the programme s offerings, you might want to sign up for the weekly electronic newsletter. You ll never miss a thing! To register, send an to studiumgenerale@tbm.tudelft.nl. The latest programme can also be found on Studium Generale Faculteit TBM Room a Jaffalaan BX Delft Tel.: +31(0) studiumgenerale@tbm.tudelft.nl Web site: Secretariat opening hours: Monday through Thursday, 9.00 uur to BioProduct Design

19 University Profile 1.15 Delta Delta is TU Delft s information and opinion journal, published by a journalistically independent editorial board. Delta Editorial Board University Library, room Prometheusplein ZC Delft Postal address: Postbus AC Delft Tel.: +31 (0) delta@tudelft.nl Web site: The electronic version of this study guide can also be found on the faculty s campus web site. 1 Study Guide 2009/2010

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21 2. Information about the PDEngprogramme in BioProduct Design

22 Information about the PDEng-programme in BioProduct Design 2.1 People responsible for the programme/important addresses Department of Biotechnology Delft University of Technology Julianalaan BC Delft Tel: +31 (0) Fax: +31 (0) Programme Director Prof.dr. Han de Winde Secretariat: Ms. Jennifer Achterhof Tel: +31 (0) The Programme Director is chairman to the Selection, Programme and Exam Committee, responsible for the content of the programme and the selection of candidates. Course Coordination Team Drs. Florien de Brouwer Tel: +31 (0) Drs. Janine Kiers, M. Biotech Tel: +31 (0) The Course Coordination Team is responsible for the organisation of the programme, dealing with public relations, selection, appointment and monitoring of PDEng trainees, quality assurance of the programme. 2 BioProduct Design

23 Information about the PDEng-programme in BioProduct Design Research on BioProduct Design and supervision of projects Prof. dr. ir. Klaas van t Riet k.vantriet@tudelft.nl Drs. Janine Kiers j.a.kiers@tudelft.nl The research group assures the scientific quality of design projects and provides education in BioProduct Design. The research group analyses the bioproduct design process. It supervises design projects and assures their quality. The group provides education in BioProduct Design. Institute BSDL Department of Biotechnology Coordinator: dr.ir. Lies van der Meer-Lerk Office Manager: ms. Ger Aggenbach Tel: +31 (0) Secretary: ms. Ginie Klumpers Tel: +31 (0) Research Groups in the Department of Biotechnology Analytical Biotechnology (ABT) prof.dr. Peter D.E.M. Verhaert prof.dr.ir. Gijs W.K. van Dedem (emeritus) Web site: Biocatalysis and Organic Chemistry (BOC) prof.dr. Isabel W.C.E. Arends prof.dr. Roger A. Sheldon (emeritus) Web site: Bioprocess Technology (BPT) prof.dr.ir. Sef Heijnen Web site: Bioseparation Technology (BST) Prof. dr.ir. Luuk A.M. van der Wielen Web site: 2 Study Guide 2009/2010

24 Information about the PDEng-programme in BioProduct Design Environmental Biotechnology (EBT) prof.dr.ir. Mark C.M. van Loosdrecht prof.dr.ir. Mike S.M. Jetten (part-time) prof.dr. J. Gijs Kuenen (emeritus) Web site: Enzymology (ENZ) prof.dr. Wilfred R. Hagen prof.dr. Simon de Vries Web site: Industrial Microbiology (IMB) prof.dr. Jack T. Pronk prof.dr. Han de Winde prof.dr. Hans van Dijken (part-time) prof.dr. Paul Hooykaas (part-time) Web site: Complex Fluids Theory Prof.dr. T. Odijk Web site: Biotechnology and Society (BTS) prof.dr. Julian Kinderlerer Web site: 2 BioProduct Design

25 Information about the PDEng-programme in BioProduct Design 2.3 Faculty Building Addresses (see map) Faculty of Applied Sciences Visiting address: Lorentzweg CJ Delft The Netherlands (building 22 on map) Postal address: PO Box GA Delft The Netherlands Tel: +31 (0) Fax: +31 (0) info@tnw.tudelft.nl Web site: Department of Biotechnology / Biochemical Engineering Director Prof. J.H. (Han) de Winde Visiting address: Julianalaan BC Delft The Netherlands (building 5 on map) Postal address: Julianalaan BC Delft The Netherlands Tel: +31 (0) Fax: +31 (0) s.j.goede@tudelft.nl Web site: 2 Study Guide 2009/2010

26 Information about the PDEng-programme in BioProduct Design Department of Chemical Technology / DelftChemTech Director Prof. E.J.R. (Ernst) Sudholter Visiting address: Julianalaan BL Delft The Netherlands (building 12 on map) Postal address: PO Box GA Delft The Netherlands Tel: +31 (0) Fax: +31 (0) dct-secretariaat@tnw.tudelft.nl Web site: Imaging Science and Technology Laboratory of Applied Physics Address: See Faculty of Applied Sciences Tel: +31 (0) Fax: +31 (0) ist@tnw.tudelft.nl Web site: Kavli Institute of Nanoscience Lorentzweg CJ Delft nanoscience@tnw.tudelft.nl Department of Multi-Scale Physics Director: Prof. H.E.A. (Harry) van den Akker Laboratory of Applied Physics Address: See Faculty of Applied Sciences and Kramers Laboratorium voor Fysische Technologie Prins Bernhardlaan BW Delft (building 15 on map) Tel: +31 (0) Fax: +31 (0) msp@tnw.tudelft.nl Web site: 2 BioProduct Design

27 Information about the PDEng-programme in BioProduct Design NanoScience Laboratory of Applied Physics Address: See Faculty of Applied Sciences Tel: +31 (0) Fax: +31 (0) Web site: Radiation, Radionuclides & Reactors Reactor Institute Delft Mekelweg JB Delft The Netherlands Tel: +31 (0) Fax: +31 (0) Web site: The various Applied Sciences buildings have their own cafes, where people gather regularly for a chat and a drink. These are: The TPKV, in the D-wing basement of the Applied Physics building at Lorentzweg 1, open on Fridays from Ecast, in the basement of the ChemTech building at Julianalaan 136, open Thursdays from t Keldertje, room in the attic of the Department of Biotechnology, Julianalaan 67, open Fridays from Courses: Registration and Grading Course registration You are responsible for registering for all courses in your programme. You can register as soon as your programme is approved or when a course is approved individually. For Advanced Courses you are advised to sign in as soon as possible and well in advance as places usually fill up quickly. As "PDEng trainee" always try to sign in for the reduced PhD-student fee. Examinations and exams Please note: Examinations are usually called tentamens in Dutch. Formally an examen in Dutch is the degree audit taking place at the end of a programme phase such as a Propaedeuse (end of first year), a Bachelor or 2 Study Guide 2009/2010

28 Information about the PDEng-programme in BioProduct Design a Master phase. These examens are formalities in the Dutch university system. There are no end-of-year examinations! Study progress administration You are responsible to keep track of your study results in your Excel Study File. You will discuss your study progress in regular meetings with the Course Coordinators. You need to check regularly that your file is up-todate and, when approaching the finalisation of your programme, that it is complete. Course results administration may differ: 1 For regular Master courses at TU Delft, just provide the lecturer with your name and study number and it should work out fine. If an assignment is part of the course, you have to work together with another PDEng-trainee, as your work is usually evaluated differently from the work of Master students. Sometimes also the coursecode is therefore different, you and the lecturer are responsible for the correct administration of this. 2 For special PDEng assignments etcetera: The teacher should complete a TU Delft grade sheet and send it to the coordinator. 3 For Advanced Courses the coordinator need a copy of the course certificate. For AC s with assignment we also need a grade sheet. 4 For all courses you take outside TU Delft: the coordinator needs an official letter of the lecturer stating the name of the course, your name, grade, study number and the amount of ECTS points. NB: Please note that you are responsible for providing the coordinators with all your grades in time for the diploma. Examination registration In order to take an exam, you need to register in advance. Since the registration may differ from one course to another, you need to check with the lecturer on how to register. TAS In TAS (Tentamen aanmeld system) you can find where and when an exam will take place. PDEng. trainees need to log in as demo, password demo, go to overview, mark the box limit selection to and enter course code. Credits, marking scheme and grades The weight of all modules at TU Delft is expressed in European Credit Transfer System (ECTS) points. One year of study comprises 60 credit points or 1680 hours of study in an academic year. This includes lecture hours, homework, projects, practical work etc. 2 BioProduct Design

29 Information about the PDEng-programme in BioProduct Design This means that there is no strict relation between lecture hours and credit points, but a general rule is that each module, which takes one lecture hour per week for the duration of one semester, earns you about 1 credit point. The scale used for grading is 1-10, i.e. each examination awards a maximum grade of 10. The passing mark is a 6 and a 5 or lower is considered a fail. In some instances you are not awarded a numerical grade, but you either pass ( voldoende ) or fail ( onvoldoende ).This system is quite common for practical work. A table converting the Dutch grading system into the European one has been proposed, but this has not yet been adopted at TU Delft. The table below shows an unofficial translation from Dutch grades into ECTS grades. Dutch Distribution ECTS Grading system percentage grade 8 <grade < 10 best 10 % A 7.5<grade < 8 next 25 % B 7 <grade <7.5 next 30 % C 6 <grade <7 next 25% D 5.5<grade <6 next 10% E grade < 5.5 Fail F or FX Graduation Ceremony The great day has arrived! You have fulfilled all obligations of your Designer Programme and you can participate in the graduation ceremony. You should make sure that your grades are available at least two weeks in advance. This means that you should plan your Final Presentation of your Design Project at least two weeks in advance of the ceremony. A check will be performed to ensure that you are entitled to graduate. The Graduation Ceremony is, in intself, merely a formality, but it marks an important milestone in your career and provides the opportunity for you to publicly congratulated by family, friends and academic staff - much deserved accolades after an intensive period of study! 2 Study Guide 2009/2010

30 2.5 The building Information about the PDEng-programme in BioProduct Design Designer Office The office for the Designers in the Department of Biotechnology is equipped with computing and internet facilities. The key to the PDEngroom requires a deposit of EUR25 and can be collected from Ms Ginie Klumpers. The deposit will be refunded to you upon return of the key. The location is: Department of Biotechnology Julianalaan BC Delft The Netherlands Room Tel: +31 (0) Regulations Department of Biotechnology The Course coordinator of BioProduct Design will provide you with the form to register for the Department of Biotechnology. You will also receive the Safety Guide. Everyone is obliged: to read the Safety Guide, to participate in the Fire drill, to register for the department of Biotechnology, to have their picture taken for the employees boards. Please observe the rules and regulations for working at the Department outside of office hours!! Access to the building Delft University of Technology has a university card system called Campus Card. The Campus Card has several functions: an ID function that, together with the Campus Card, allows you to participate in exams and working groups. an identification function that allows you to make use of the services of the TU Delft Library. a right of entry to some TU buildings, among them all buildings of the Faculty of Applied Sciences. This Campus Card is a valuable document and must be handled as such. You will receive a letter stating to collect your card. The Campus Card is 30 BioProduct Design

31 Information about the PDEng-programme in BioProduct Design comprised of a (digital) photo. New employees can have their picture taken at the OSA building (Jaffalaan 9a). You can have a passport photo taken every weekday from 09:30 to 16:30. If the Campus Card has been lost or damaged, you can request a duplicate Campus Card (price: EUR 3.00). When using the academic or exam facilities, the Campus Card must be shown. If you are unable to show your Campus Card, you will not be permitted to use the facilities. Hours registration Your name will be in the list down at the clock on the ground floor. You need to enter your arrival time and departure time in the list. If you take more than half an hour lunch break, you need to enter lunch leaving and return as well. In this list you register your WORKING HOURS - your nonworking presence in the building (e.g. 't Keldertje) should not be registered here Lunch Officially you have half an hour lunch time. If you take a longer lunch break, you have to register leaving time and return in the list down at the clock. TIM leave registration system If you want to take holidays, you need to enter them in TIM (hours.tudelft.nl). Please ask your PDEng colleagues how to handle it. Your request will be approved by L van der Meer. Call in sick What to do when you are ill and can not come to work? Call the secretary of Bioprocesstechnology (Jennifer or Maltie or Miranda) at before 9:00 am. Once you are fine again, let them know as well before 9:00 am on the day you return to work. If you have a serious illness (with absence longer than one week) please inform the coordinator as well. Beamer reservation A beamer can be booked and collected at the workshop at the ground floor. Room reservation A lecture or discussion room can be booked at secretary Ginie. 3 Study Guide 2009/2010

32 Information about the PDEng-programme in BioProduct Design Mail For internal mail you put mail in yellow envelopes (A3 format). For business mail sent outside the university you can use the white university envelopes. You do not have to put a stamp on it and leave it in the huismeester room. 2.6 Other Important Information Refund of books and travel The programme can refund your study books for 50% and traintickets for traveling. Drop off your completed C1 form (including remarks section: what is the purpose of your expense) in the mailbox of the coordinator. The DIM 1 and 2 codes of the BioProduct Design programme are TAT and T Dutch Language course for foreigners TU Delft offers a Dutch course, which is partly on your own expense. Healthcare system The Dutch healthcare system differs from most other countries. The General Practitioner plays an important role and is the first one with whom you should get into contact when you experience medical problems. For this reason it is advisable to register with a General Practitioner in your environment. How to find a general practitioner? Also for finding a dentist. Look at: When having complaint or problems which are related to your working environment then you can make an appointment with the company doctor, phone number: Health insurance Most of the staff of the TU Delft has their insurance at Ohra ( Ask one of the PDEng trainees about the insurance. Personnel Department The personnel department is situated in the building of the Department of Civil Engineering and Geosciences at the Stevinweg 1, 5th floor, in the centre of the university campus. Residence permit (if applicable) Normally you will receive a letter from IND 3 months prior to your ending data of residence permit reminding you to extend your residence permit. 3 BioProduct Design

33 Information about the PDEng-programme in BioProduct Design You are responsible for the extension and payment of your residence permit. 2.7 Useful (web) Addresses (general Information about Delft University, history, programmes, research, etc.) (information about all MSc and MSc programmes offered by Delft University of Technology, information about the requirements, how to apply, costs, funding, insurance, housing, medical and pastoral care, facilities for special needs students etc.) (TU Delft Sports & Cultural Centre) (information about the city of Delft) (for activities in the nearby city of Den Haag) (activities in Rotterdam) (activities, news, public transport in and around Amsterdam) 3 Study Guide 2009/2010

34 Information about the PDEng-programme in BioProduct Design Student Restaurants in Delft - University main cafeteria, Aula, Mekelweg 5 - SnC Café, Mekelweg 8 - Sint Jansbrug, Oude Delft Koornbeurs, Voldersgracht 1 - DSB, Oude Delft CSR, Oude Delft 9 - De Bolk, Buitenwatersloot Novum, Verwersdijk BioProduct Design

35 3. Designer Programme

36 Designer Programme 3.1 Programme structure of BioProduct Design Credits and Duration of the programme The complete programme consists of 120 European Credits, EC, as defined in the European Credit Transfer System. The trainees take 60 EC per year which is a full time study load. The duration of the programme is 2 years. Preparing your individual programme Depending on your educational background and your envisaged development, you draw up your own programme together with the Course Director and one of the Course Coordinators. The programme is defined in discussion with the PDEng trainee, tailoring it to the trainee s background and interest, while controlling the balance between deepening and broadening coursework. The PDEng trainee makes a proposal after identifying interesting courses at and other websites (see paragraph 4.2). He or she needs to take into acount the scheduling of the courses (Blackboard.tudelft.nl) and the work balance (e.g. 30 ects per semester). Scheduling The academic year at Delft University of Technology is divided in 2 semesters, from September till January and from February till June. Each semester consists of 2 periods, in September starts period 1 and in February starts period 3. During these semesters courses are given. July and August are regarded as period 5, the period for re-sits, holidays and the Group Design Project. Please note that courses exclusively for PDEngtrainees or Advanced Courses may be scheduled in lecture-free weeks. 3.2 First year The first year consists of coursework and the Group Design Project. Advanced Coursework 43 EC The coursework is divided in three phases that are not necessarily separated in time. Due to its nature, phase 1 is in the first months of the programme: 3 BioProduct Design

37 Designer Programme Phase 1 Equalization This phase is to eliminate deficiencies. Depending on the PDEng trainee s background and intended Study Programme, 0 to 9 EC may be included to obtain a uniform trainee population. Phase 2 Deepening The PDEng trainee develops him/herself in the area of his/her background, but on a new level (post-msc) or with a different approach of the material. The courses are organized for PhD and PDEng students or professionals, or contain new, e.g. integrating, approaches. Phase 3 Broadening The PDEng trainee broadens his/her scope and learns more in disciplines that are new to him/her. These courses may be on MSc or BSc level, or are specifically organized for PDEng-trainees. The PDEng trainee defines his/her individual Study Programme in discussion with the Programme Coordinator. The trainee has a certain freedom to choose from the Deepening and Broadening courses. Care is taken that the courses form a balanced total, which means that a certain specialization is necessary, while at the same time the different disciplines are represented. Special attention is given to the integration of different disciplines. Level of the courses In the definition of a PDEng trainee s programme, care is taken to balance deepening and broadening courses. Deepening courses are of an advanced, post-msc level and are organized for PDEng and/or PhD students and professionals. Broadening courses may be of a post-graduate, but also of an MSc, or occasionally even of a BSc level. For MSc-courses, you attend the lectures with MSc students and in the content of the examination or the evaluation of the performance it may be taken into account that you are at a post-msc level. For group assigments, you work in principle together with your fellow PDEngtrainees. Core Courses & Projects The obligatory part concerns the Group Design Project and its theoretical preparation, several broadening disciplines, plus the course Industrial BioProduct Design. 3 Study Guide 2009/2010

38 Designer Programme Title Credits Design Theory and Methodology 3 Group Design Project 17 Project Management 2 Economic Evaluation 6 Turning Technology into Business 6 Industrial BioProduct Design 3 Total 37 EC Elective courses The trainee s specialization is determined by the choice of coursework in combination with the Individual Design Project. The following specializations are identified: Drug Design & Diagnostics Cell Factory Functional Genomics & Bio-informatics Molecular Design The 23 (maximum) EC can be chosen in different areas. At and in this studyguide (chapter 4) you find a non-exhaustive list of courses and their course codes for the PDEng programme in BioProduct Design. Please note that the list is not complete. You are encouraged to suggest suitable courses yourselves. Websites providing information on additional courses you can include in your programme: BODL Biotechnologie Opleidingen Delft Leiden / Biotechnology Studies Delft Leiden: LACDR Leiden Amsterdam Centre for Drug Research: LIC Leiden Institute of Chemistry: VLAG Graduate School Voeding, Levensmiddelentechnologie, Agrobiotechnologie en Gezondheid: 3 BioProduct Design

39 Designer Programme Leiden Lecture Series in the Master programme Bio-Pharmaceutical Sciences: LST Master programme Life Science & Technology: OSPT Dutch Graduate School on Process Technology: Group Design Project 17 EC In the Group Design Project, the trainees work in groups of 4 (range 3-6) students on a design project in collaboration with industry. The supervision is in the hands of a steering group consisting of an industrial principal, and academic representatives, with ample (industrial or academic) design experience. The team experiences working in an industrial context, dividing tasks within the team, interacting with different stakeholders and planning and control issues. At the same time, a detailed design has to be delivered, in which systematic and quantitative argumentation is provided for the choices made. The design team communicates regularly with the industrial principal and supervisors by intermediate reporting, which includes presentations and meetings. Code Course Title Credits ST6813 Group Design Project Second year The second year of the programme is devoted to the Individual Design Project (60 EC) in (or in collaboration with) industry. This project is performed in, or in collaboration with, the R&D department of an industry or as a developer in a smaller industry. It may be providing a solution for a specific problem, but it may also regard the whole design process, from idea to feasibility. As in the Group Design Project, a focus is on the delivery of the systematic and quantitative argumentation for the final design solution. The supervision of this project is handled by at least one academic supervisor and one industrial supervisor. 3 Study Guide 2009/2010

40 Designer Programme Code ST6902pr ST6902th ST6902vc Title PDEng Individual Design Project - practice PDEng Individual Design Project - theory PDEng Individual Design Project - communication 3.4 Timetables You can find the timetables of your programme on the Blackboard website. 40 BioProduct Design

41 4. Course Descriptons

42 Course Descriptons BE3131TU Fermentation Technology ECTS: 3 Responsible Instructor Contact Hours / Week x/x/x/x Dr.ir. R.G.J.M. van der Lans (R.G.J.M.vanderLans@tudelft.nl), Prof.dr.ir. J.J. Heijnen (J.J.Heijnen@tudelft.nl) 2/2/0/0 Education Period 1, 2 Start Education 1 Exam Period 2 Course Language Expected prior knowledge Course Contents Study Goals Education Method Literature and Study Materials Assessment Permitted Materials during Tests Enrolment / Application Location English Basic biosciences (biochemistry and microbiology) and Engineering principles. Stoichiometry, thermodynamics, kinetics of growth and product formation, Metabolic networks, Modeling of batch, chemostat, fed batch fermentation, Role of mass transfer, mixing and heat transfer. Designing/evaluating industrial fermentation processes from technological and microbial fundamentals. Lectures, exercises. Lecture notes on Blackboard Recommended: Basic Bioreactor design, van 't Riet en Tramper, Dekker, New York 1991 Assignments and examination. PdEng trainees are subject to special requirements (code ST6532). Open book Via blackboard Delft BE3141TU Environmental Biotechnology ECTS: 3 Responsible Instructor Contact Hours / Week x/x/x/x Prof.dr.ir. M.C.M. van Loosdrecht (M.C.M.vanLoosdrecht@tudelft.nl) 0/0/4/0 Education Period 2, 3 Start Education 2 Exam Period 3 4 BioProduct Design

43 Course Descriptons Course Language English Course Contents - Stoichiometry and kinetics in environmental biotechnology processes; - reaction/diffusion in biofilm systems; - dynamic modelling of activated sludge processes; - anaerobic processes; - nutrient removal; - design of integrated purification processes. Study Goals - To get a general view on environmental biotechnological processes - To be able to design environmental biotechnological processes. Education Method Literature and Study Materials Prerequisites Assessment Remarks Lectures and assignments Lecture notes and handouts. General reactor engineering courses The final grade is determined from the results of the lecture assignments (60%) and an oral examination The course is oriented towards the design of environmental biotechnological processes. The specific aspects of using open mixed microbial cultures and undefined substrates will get particular attention. Topics: Stoichiometry and kinetics, mass transfer processes, biomass retention systems, dynamic modelling of mixed microbial cultures, process design.the case study is focussing on a global design of an industrial treatment. (ABET)Planning: 14 hours class, 46 hours assignments, 20 hours preparation of exam BE316 Microbial Physiology ECTS: 4 Responsible Instructor Contact Hours / Week x/x/x/x Dr.ir. A.J.A. van Maris (A.J.A.vanMaris@tudelft.nl) periode 3: 2 uur in de eerste week, 2 uur in week 3 en 2 uur in week 7 Education Period 3 Start Education 3 Exam Period 3 Course Language Course Contents Study Goals English Microbial metabolism under nutrient excess and nutrient limited conditions. Mixed substrate utilization, fermentation, aerobic- and anaerobic respiration and methanogenesis. Quantitative physiology. Selection and evolution. Microbial interactions with industry and our environment. The role of microorganisms in the geochemical elemental cycles. Basic knowledge on microbial physiology. Education Method Selfstudy combined with 3 Q&A sessions. 4 Study Guide 2009/2010

44 Course Descriptons Books Assessment Brock Biology of Microorganisms, Martinko, Madigan (12th ed). Oral/Written exam BE320 Analytical Biotechnology ECTS: 3 Responsible Instructor Contact Hours / Week x/x/x/x Prof.dr. P.D.E.M. Verhaert (P.D.E.M.Verhaert@tudelft.nl) 0/0/0/4 Education Period 4 Start Education 4 Exam Period 4 Course Language Course Contents English This course treats various aspects of Analytical Biotechnology, in particular those which comprise the current research topics of the Section at the TUDelft Biotechnology Department bearing that name. The goal is to make (bio)chemical engineers in spe familiar with modern Analytical Biotechnology. The following items are discussed: - Analytical miniaturization (towards single cell analysis on chip). - Peptidomics and its link to modern Biology research (from comparative neurobiology, over the discovery of novel drug candidates in amphibian skin, to microbiology). - Proteomics and its applications with particular focus on the pharmaceutical and biotechnology industry. - Mass spectrometry imaging. In this framework, special attention will go to the technology of protein/ peptide mass spectrometry and its many applications for qualitative as well as quantitative analyses. Papers related to other aspects of interest in the field of Analytical Biotechnology will be selected, presented and discussed by the course participants. Study Goals Education Method Literature and Study Materials Prerequisites Understanding of a selection of modern analytical techniques, applied in the field of biotechnology (and beyond). Primarily lectures, but also presentations by the course attendees themselves of selected papers on the topic. All course material, including lecture presentations as well as selected literature, is made available on blackboard. Basic biochemistry Assessment Written exam or term paper. 4 BioProduct Design

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