Nancy N. Huang Research Interests Education Harvard University College of William and Mary Thomas Jefferson High School for Science and Technology

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1 Curriculum Vitae Nancy N. Huang Assistant Professor The Colorado College Biology Department 14 E. Cache La Poudre Street Colorado Springs, CO Research Interests I am a developmental biologist who uses techniques in genetics, molecular biology, and cell biology to study early embryonic development in the nematode worm C. elegans. I am currently studying how RNA binding proteins act in combination to control when and where maternally provided mrnas are translated into protein. Education Harvard University Dept of Molecular and Cellular Biology in Cambridge, MA ( ) Ph.D in Biology Advisor: Dr. Craig P. Hunter Dissertation Title: Pattern to Polarity in the C. elegans Embryo National Science Foundation Predoctoral Fellow College of William and Mary in Williamsburg, VA ( ) B.S. magna cum laude Phi Beta Kappa Major in Biology with highest honors. Minor in Chemistry Thomas Jefferson High School for Science and Technology in Alexandria, VA ( ) Professional Experience Assistant Professor at The Colorado College Department of Biology (Fall 2008-present) Involve undergraduates in research using genetics, molecular biology, and cell biology to study early embryonic development in the nematode worm C. elegans. Teach six courses a year, including Cell Biology w/lab, Genetics w/lab, Developmental Biology w/lab, Evolution, and mentored research. Instructor at Harvard Extension School ( ) Taught Introduction to Genomics with computer lab Fall 2007 Taught Graduate Research Methods and Scholarly Writing in the Biological Sciences o Topic: Cell-cell communication Spring 2005 and Fall 2005 o Topic: RNA interference (RNAi) Fall 2006 and Fall 2007 Preceptor at Harvard University ( ) Course in Genetics, Genomics and Evolution with lab o Designed and supervised the laboratory and discussion section components of a new course with ~400 students, 4 lecturers, and ~25 teaching fellows a year. Postdoctoral Fellow at Harvard University Dept. of Molecular & Cellular Biology ( ) Advisor: Dr. Craig P. Hunter Project: Distinct protein domains regulate stability and patterning of MEX-3 in the C. elegans embryo. 1

2 CV Nancy N. Huang Teaching Fellow at Harvard University (6 semesters from ) Nominated for Levenson Memorial Teaching Prize (2004) External Grants and Fellowships National Science Foundation Major Research Instrumentation ( ) $59,487 for Acquisition of a Fluorescence Stereomicroscope to Enhance Undergraduate Research at Colorado College (# ) PIs: Darrell J. Killian and Nancy N. Huang Grant from the Medical Education and Research Institute of Colorado (MERIC) (2009) $26,836 for microscope equipment. Merck/AAAS Undergraduate Science Research Program ( ) $60,000 over three years for summer stipends for students conducting interdisciplinary research. Collaboration among six (6) faculty members in chemistry and biology. National Science Foundation Predoctoral Fellowship ( ) Internal Funding and Support Taber Fund $1,160 (Fall 2010) for two thesis students to travel and present posters at 2011 American Society for Cell Biology meeting in Denver, CO.$4,477 (Fall 2008) Dean s Colorado College Natural Science Division Research Grants $4, (Fall 2011) $4,500 (Fall 2010) $4,720 (Fall 2009) $3,200 (Spring 2009) $4,477 (Fall 2008) Dean s Summer Research Grant $4,000 (Summer 2010) Faculty Development Block 1 month release time (awarded for , but cancelled due to budget constraints) Publications Huang, N. N. and Hunter, C.P. (in preparation for Development). Distinct protein domains regulate stability and patterning of Huang, N. N., Mootz, D. E., Walhout, A. J. M., Vidal, M., and Hunter, C. P. (2002). MEX-3 interacting proteins link cell polarity to asymmetric gene expression in Caenorhabditis elegans. Development 129, Presentations American Society for Cell Biology Meeting, International C. elegans Meeting,

3 3 CV Nancy N. Huang Santa Cruz Developmental Biology Meeting, International C. elegans Meeting, Society for Developmental Biology Meeting, Huang, N. N., Mootz, D., Walhout, A. J., Vidal, M., and Hunter, C. P. The Putative RNAbinding Proteins MEX-5, MEX-6, and SPN-4 Regulate MEX-3 Localization and Activity to Control PAL-1 Spatial Patterning. East Coast Worm Meeting, Huang, N. N., Mootz, D., Walhout, A. J., Vidal, M., and Hunter, C. P. The Putative RNAbinding Proteins MEX-5, MEX-6, and SPN-4 Regulate MEX-3 Localization and Activity to Control PAL-1 Spatial Patterning. Society for Developmental Biology Meeting, (Selected speaker) Huang, N. N., Mootz, D., Walhout, A. J., Vidal, M., and Hunter, C. P. MEX-3 Interacting Proteins Link Cell Polarity to Asymmetric Gene Expression in C. elegans. International C. elegans Meeting, (Selected speaker) Huang, N. N., Mootz, D., Walhout, A. J., Vidal, M., and Hunter, C. P. MEX-3 Interacting Proteins Link Cell Polarity to Asymmetric Gene Expression. Boston Area Worm Meeting, (Speaker) Huang, N. N. MEX-3 Interacting Proteins Link Cell Polarity to Asymmetric Gene Expression in C. elegans. Society for Developmental Biology Meeting, Huang, N. N., Mootz, D., Walhout, A. J., Vidal, M., and Hunter, C. P. MEX-3 Interacting Proteins Required to Regulate pal-1 Translation. International C. elegans Meeting, Huang, N. N., Mootz, D., Walhout, A. J., Vidal, M., and Hunter, C. P. Identification of proteins that may interact with MEX-3 to regulate pal-1 translation. Student Presentations American Society for Cell Biology Meeting, 2011 Amy Lin*, Kathryn Reichard*, Anjali R. Desai*, Kroger Schwartz*, Peter Heng*, and Nancy N. Huang. RNAi screen of predicted E3 ubiquitin ligases that may mark MEX-3 for degradation in the Caenorhabditis elegans embryo Midstates Consortium for Math and Science Undergraduate Research Symposium, 2011 Amy Lin* and Nancy N. Huang. RNAi screen of predicted E3 ubiquitin ligases that may mark MEX-3 for degradation Midstates Consortium for Math and Science Undergraduate Research Symposium, 2009 Jessica Olson* and Nancy N. Huang. Identification of genes required for cell differentiation and translational regulation in the Caenorhabditis elegans embryo

4 CV Nancy N. Huang Daniela Lopez-Morales* and Nancy N. Huang. Selective RNAi Screen of C. elegans for Embryonic Lethality and Characterization of Arrested Embryos * Denotes undergraduate Presenting authors are underlined Mentored Student Research Student (Research Experience) Major and Year Career Path Peter Heng (Summer, BY309) Biology '13 Plans to apply to medical school Amy Lin (Summer, BY409, BY499) Neuroscience '12 Plans to apply to Ph.D. programs. Kathryn Reichard Biology '12 Plans to apply to Ph.D. programs (Summer, BY409, BY499) Anjali Desai (Summer, BY409) Biochemistry '12 Plans to apply to medical school Nikhil Ranadive (BY309, BY409) Biology '11 Plans to apply to medical school Kroger Schwartz (Spring 2011) Biology '11 Undecided Chelsey B. Coles (BY309) Biology '11 Accepted into medical school for 2012 Alyssa R. Kallweit (BY309) Biology '11 Plans to apply to Ph.D. programs Akie Mochizuki (BY309) Biochemistry 11 Ph.D. program at Michigan State Univ. Daniela Lopez-Morales Biochemistry '10 Applying to nursing school (Summer, BY309) Jessica L. Olson Biology '10 Plans to apply to medical school (Summer, BY409, BY499) Somhrita Dutta (BY309) Neuroscience '10 Ph.D. program at Tulane University Brian D. Engle (BY309) Biochemistry '10 Applying to medical school Lauren E. Weber (BY309) Biology 10 Applying to medical school Han N. Yi (BY309) Biology '10 University of Denver Dental School College Service Health Professions Advisory (HPA) Committee at Colorado College (Summer 2009-present) Read CV, transcripts, test scores, personal statement, and 3-5 recommendation letters for all students applying to medical or dental school through Colorado College (30-40 students per year). In collaboration with three colleagues, write composite letters of evaluation so that medical and dental schools have a more complete and objective summary of the applicant. Committee chair in Spring and Summer 2011 Curriculum Revision Co-Coordinator for Biology Dept at Colorado College (Fall 2009-Fall 2010) Along with a colleague, was responsible for coordinating the biology department discussions on curriculum revision. Submitted a proposal for approval by the College faculty after three years of discussion. Changes include the addition of two new tracks within the major and revision of 27 courses, including substantial changes to the introductory courses. Screening Committee for Tenure Track Hire in Biology Dept at Colorado College (Fall 2010) Reviewed 90 applications and, along with five colleagues, chose 25 candidates for consideration by the entire Biology department. Biology Seminar Series Organizing Committee at Colorado College (Fall 2008-Spring 2011) Along with a colleague, arrange roughly 8 seminars per year. 4

5 Webmaster for Biology Dept at Colorado College (Fall 2009-present) Academic Advisor at Colorado College (Fall 2009-present) Advise students per year. CV Nancy N. Huang Pre-Health Advising Group at Colorado College (Fall 2009-present) Available to advise students interested in the health professions, regardless of their major. Bypass Exam Coordinator for BY210-Cell Biology (Fall 2009-Spring 2011) Neuroscience Program Advisor at Colorado College (Spring 2009-present) Phi Beta Kappa Society Faculty Member at Colorado College Participate in selection and induction of new members (Spring 2009-present) Helped organize several events for a Phi Beta Kappa visiting scholar (January 2009) Admissions Office Open House Participant at Colorado College (Fall 2008-present) Regularly participate in open house events by hosting perspective students in class and meeting with perspective students and parents for lunch or dinner. Fall Forum at Colorado College (Fall 2010) Led a session entitled The Mighty Worm on the use of the nematode C. elegans in biomedical research. ACM Conference on Women and The Academy at Coe College (September 2009) Represented Colorado College. Midstates Consortium for Math and Science Undergraduate Research Symposium for Biological Sciences and Psychology at Washington University in St. Louis (Fall 2009) Accompanied 7 students as the Colorado College faculty representative. Served on a faculty panel on careers at liberal arts colleges for graduate students and postdocs at Washington University. Board of Freshmen Advisors at Harvard University ( ) Science Advisory Committee at Harvard University ( ) Participated in discussions that led to substantial changes in the introductory courses in the life sciences. Professional Societies Genetics Society of America Society for Developmental Biology American Society for Cell Biology Council on Undergraduate Research American Association for the Advancement of Science Professional Activities Table Leader for Career Discussion and Mentoring Roundtable on Teaching and Research in Primarily Undergraduate Institutions 2010 American Society for Cell Biology meeting Judge for student posters on Mechanisms and Function of RNA interference and small RNAs 2009 International C. elegans meeting 5

6 Science Fair Project Advisor For a student at Palmer High School in Colorado Springs (Fall 2010) o First place at regional science fair for all senior high projects For a student at North Middle School in Colorado Springs (Spring 2009) CV Nancy N. Huang Textbook Reviewer Principles and Analysis of Genetics: An Integrated Approach by Sanders and Bowman. Pearson Education. (2010) Molecular Biology by Clark. AP Cell Press. (2010) Introduction to Genetic Principles by Hyde. W.H. Freeman Publishers. (2007) Curriculum Consultant and Teaching Assistant for Crimson Summer Academy at Harvard University ( ). Worked with high school teachers to develop lab activities for rising high school sophomores and juniors from disadvantaged backgrounds who take part in the 4 or 6 week program. Guest Speaker Davidson Institute for Talent Development, Boston gathering (June 2006) Newton North High School, Newton, MA (May 2003) American Junior Academy of Sciences, Boston convention (February 2002) Curriculum Consultant for HHMI-MCB Outreach Program at Harvard University (Fall 2002) Designed and led laboratory exercises for high school teachers for implementation into their classrooms. Prepared background materials, laboratory protocols and thought questions appropriate for advanced high school students. Volunteer Tutor at Cambridge Rindge and Latin High School in Cambridge, MA ( ) Adult Skills Program Volunteer in Williamsburg, VA ( ) 6